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Wyniki wyszukiwania dla: POLYCYSTIC OVARY SYNDROME (PCOS)
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DAB vs DAB+ Radio Broadcasting: a Subjective Comparative Study
PublikacjaIn the age of digital media, delivering high quality content to consumers is one of the most demanding tasks. There exist numerous broadcasting standards, with different pros and cons, and the DAB/DAB (Digital Audio Broadcasting) system is one of the most popular among them. From an engineer’s perspective, efficient resource management under limited bandwidth conditions has always been a challenge. In this paper a subjective quality...
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To meet or to connect? Face-to-face contacts vs ICT in cluster organisations
PublikacjaThe main purpose of the paper is to explore how cluster organisations (COs) take advantage of direct (F2F) and indirect (ICT) contacts in fulfilling their main roles. The paper addresses the research question: “How important are Information and Communication Technologies at each level of advancement of cluster cooperation?” The research was conducted in 2016 in four purposefully selected cluster organisations representing metal...
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Application of Diagnostic Ratios of PAHs to Characterize the Pollution Emission Sources
PublikacjaThe paper summarizes the potential of application of parent polycyclic aromatic hydrocarbons (PAHs) to identify their emission sources. Four parent PAHs diagnostic ratios are used for this purpose: anthracene/(anthracene + phenanthrene), fluoranthene/(fluoranthene + pyrene), benzo[a]pyrene/(benzo[a]pyrene + chryzene) and indeno[1,2,3-c,d]pyrene/(indeno[1,2,3-c,d]pyrene + benzo[g,h,i]perylene). The compounds of each ratio have the...
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Inhibiting activity of HIV-1: protease, reverse transcriptase and integrase all together by novel compounds using computational approaches (flexible and rigid docking)
PublikacjaAcquired immunodeficiency syndrome (AIDS), caused by human immunodeficiency virus type 1 (HIV-1) infection, is one of the most challenging diseases in recent decades. Nevertheless the shortcomings of chemical drugs such as toxicity, lack of curative effects, the search for more potent anti-HIV agents have been focused in our study. In current study, novel scaffold was designed having a benzyl and imidazole in it which are very...
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Long-distance quantum communication over noisy networks without long-time quantum memory
PublikacjaThe problem of sharing entanglement over large distances is crucial for implementations of quantum cryptography. A possible scheme for long-distance entanglement sharing and quantum communication exploits networks whose nodes share Einstein-Podolsky-Rosen (EPR) pairs. In Perseguers et al. [Phys. Rev. A 78, 062324 (2008)] the authors put forward an important isomorphism between storing quantum information in a dimension D and transmission...
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The role of rewards and demands in burnout among surgical nurses
PublikacjaObjective: Job rewards have both, an intrinsic and an extrinsic motivational potential, and lead to employees’ development as well as help them to achieve work goals. Rewards can balance job demands and protect from burnout. Due to changes on the labour market, new studies are needed. The aim of our study was to examine the role of demands and individual rewards (and their absence) in burnout among surgical nurses. Materials and...
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ENERGY ANALYSIS OF THE PROPULSION SHAFT FATIGUE PROCESS IN A ROTATING MECHANICAL SYSTEM PART II IDENTIFICATION STUDIES – DEVELOPING THE FATIGUE DURABILITY MODEL OF A DRIVE SHAFT
PublikacjaThe article presents a continuation of research carried out concerning identification of energy consequences of mechanical fatigue within a propeller shaft in a rotating mechanical system, while working under conditions of the loss of the required alignment of shaft lines. Experimental research was carried out on a physical model reflecting a full-sized real object: i.e., the propulsion system of the ship. It is proven, by means...
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Human Computer Interface for Tracking Eye Movements Improves Assessment and Diagnosis of Patients With Acquired Brain Injuries
PublikacjaOne of the first clinical signs differentiating the minimally conscious state from the vegetative state is the presence of smooth pursuit eye movements occurring in direct response to moving salient stimuli. Glasgow Coma Scale (GCS) is one of the most commonly used diagnostic tools for acute phase assessment of the level of consciousness, together with a neurological examination. These classic measures are limited to qualitative...
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Enhanced susceptibility of SARS-CoV-2 spike RBD protein assay targeted by cellular receptors ACE2 and CD147: Multivariate data analysis of multisine impedimetric response
PublikacjaSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters the cells through the binding of spike protein to the host cell surface-expressing angiotensin-converting enzyme 2 (ACE2) or by endocytosis mediated by extracellular matrix metalloproteinase inducer (CD147). We present extended statistical studies of the multisine dynamic electrochemical impedance spectroscopy (DEIS) revealing interactions between Spike RBD and...
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Limitations of Emotion Recognition in Software User Experience Evaluation Context
PublikacjaThis paper concerns how an affective-behavioural- cognitive approach applies to the evaluation of the software user experience. Although it may seem that affect recognition solutions are accurate in determining the user experience, there are several challenges in practice. This paper aims to explore the limitations of the automatic affect recognition applied in the usability context as well as...
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Historical records of organic pollutants in sediment cores
PublikacjaAnalyses of sediment core samples are primary sources of historical pollution trends in aquatic systems. Determining organic compounds, such as POPs, in the dated sediments enables the estimation of their temporal concentration changes and the identification of the contaminant origin in local regions. Wars, large-scale fires, economical transitions, and bans on certain chemicals are reflected in the sediment organic compound concentrations....
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Relation of the polymorphism of cyp51A sequence and the susceptibility of Aspergillus fumigatus isolates to triazoles determined by commercial gradient test (Etest) and by reference methods
PublikacjaThe aim of this study was to evaluate the accuracy of commercial gradient test (Etest) in the detection of triazole resistant Aspergillus fumigatus isolates using reference microdilution methods and the analysis of sequences of the cyp 51A gene. The study was performed on twenty clinical isolates which were identified as Aspergillus fumigatus based on the DNA sequences of the ITS1-2 fragment of ribosomal DNA and the β-tubulin gene,...
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Optimized photodegradation of palm oil agroindustry waste effluent using multivalent manganese–modified black titanium dioxide
PublikacjaThis article presents a methodological approach to use manganese (Mn3+Mn7+)-modified black titanium dioxide (Mn/BTiO2) as a photocatalyst to optimize and improve visible-light-driven photodegradation of treated agro-industrial effluent (TPOME). A modified wet chemical process was used to prepare BTiO2. The BTiO2 was then wet impregnated with Mn and calcined at 300 °C for 1 h to produce Mn/BTiO2. The activity of Mn/BTiO2 was investigated...
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Chemical composition of water from roof in Gdańsk, Poland
PublikacjaThis study deals with the assessment of roof runoff waters from the region of Gdansk collected during the winter season (2007/2008). The chemical analysis includes 16 chemical variables: major ions, PAHs and PCBs measured at 3 sampling sites for 6-14 rain events. Although the data set is of limited volume the statistical data treatment using self-organizing maps (SOM) reveals the main factors controlling roof runoff water quality...
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Hysteresis curves for some periodic and aperiodic perturbations in gases
PublikacjaEvolution of sound in a medium whose properties irreversibly vary in the course of wave propagation, is studied. For example, a gas that is a particular case of a Newtonian fluid is considered. Hysteresis curves, pictorial representations of irreversible attenuation of the sound energy, in the plane of thermodynamic states are plotted. The irreversible losses in internal energy are proportional to the total attenuation and depend...
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New Type of Small Broad-Band Internal Antenna for Third Generation Mobile Phone Handsets.
PublikacjaW pracy przedstawiono nową szerokopasmową antenę łatową przeznaczoną dla telefonów komórkowych trzeciej generacji. Proponowana struktura zawiera obwód (rezonator) w kształcie litery U i zaliczana jest do klasy PIFA (planar inverted-F antenna). W trakcie procesu projektowania przeprowadzono szereg symulacji elektromagnetycznych (metoda momentów), których wyniki zweryfikowano w oparciu o pomiary charakterystyk wykonanego prototypu....
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Determination of Chemical Diffusion Coefficient of Lithium Ions in Ceramics Derived from Pyrolysed Poly(1,2-dimethylsilazane) and Starch
PublikacjaThe apparent chemical diffusion coefficient Li+ (DappLI+) in pyrolysed poly(1,2-dimethylsilazane)/starch (PSN/S) (weight ratio: 30/70) ceramic anode composite is determined by galvanostatic intermittent titration technique (GITT). The electrode material composition is C6.00N0.14H0.47O0.12Si0.13. The calculated values of DappLI+, depend on the applied potential, vary from 10-14 to 10-9 [cm2/s]. The diffusion coefficient of lithium...
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A Simulative Comparison of Ship Domains and Their Polygonal Approximations
PublikacjaThe paper investigates the impact of a precise ship domain shape on the size of collision avoidance manoeuvres. The considered collision avoidance manoeuvres include both course and speed alterations. Various ship domains are compared with their polygonal approximations, which vary in the number of points of a domain contour and placement of these points. The best of all considered approximations is determined in the course of...
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Designing drainage systems – possible application of advanced calculations and hydrodynamical modeling
PublikacjaNowadays we can observe a faster development of drainage systems than ever. This gives us an opportunity to de- sign more efficient systems that can cope with the rapid growth of cities and, what comes with it, impervious surfaces. Here the question arises, whether traditional methods used in drainage system design are potent enough to cope with the emerging prob- lems and difficulties. In this paper we will make...
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Greening procedures and analytical parameters. The polychlorinated naphthalenes analysis in complex matrices as proof of concept
PublikacjaDue to the complexity of analytical procedures employed for the determination of wide spectrum of persistent organic pollutants (POPs), it is important to consider the green character of the applied protocols and propose the greenest solutions. In this review, the green aspects of several analytical procedures used for the determination of polychlorinated naphthalenes (PCNs) (as a representatives of POPs) in different types of...
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A New Coupler Concept for Contactless High-Speed Data Transmission Monitoring
PublikacjaThis paper presents a new concept of a couplerthat can be applied to high-speed data transmission contactlessmeasurements. The proposed approach is dedicated for differentialsignal transmission monitoring in microstrip coupled lineson printed circuit boards (PCBs). The coupler, produced on aseparate PCB, is overlayed on the transmission line with thedifferential signal and delivers decoupled differential signal tothe main measurement...
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Inhibitors of glucosamine-6-phosphate synthase as potential antimicrobials or antidiabetics – synthesis and properties
PublikacjaGlucosamine-6-phosphate synthase (GlcN-6-P synthase) is known as a promising target for antimicrobial agents and antidiabetics. Several compounds of natural or synthetic origin have been identified as inhibitors of this enzyme. This set comprises highly selective L-glutamine, amino sugar phosphate or transition state intermediate cis-enolamine analogues. Relatively low antimicrobial activity of these inhibitors, poorly penetrating...
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A universal standard for health-promoting places. Example of assessment -on the basis of a case study of Rahway River Park
PublikacjaThe purpose of this paper is to contribute to development of approaches to the evaluation of the design of public open green spaces (POS). This paper presents a universal standard for the design of health-promoting urban places. The standard is a conceptual framework which was developed after visiting over one hundred public parks and therapeutic gardens in Europe and the United States. The universal standard is a simple and...
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Structural, functional, and stability change predictions in human telomerase upon specific point mutations,
PublikacjaOverexpression of telomerase is one of the hallmarks of human cancer. Telomerase is important for maintaining the integrity of the ends of chromosomes, which are called telomeres. A growing number of human disease syndromes are associated with organ failure caused by mutations in telomerase (hTERT or hTR). Mutations in telomerase lead to telomere shortening by decreasing the stability of the telomerase complex, reducing its accumulation,...
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Interspecific and intraspecific variation in organochlorine pesticides and polychlorinated biphenyls using non-destructive samples from Pygoscelis penguins
PublikacjaAs humans are present in Antarctica only for scientific and tourism-related purposes, it is often described as a pristine region. However, studies have identified measurable levels of Persistent Organic Pollutants (POPs), such as organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs), in the Antarctic region. These are highly toxic anthropogenic compounds with tendency to travel long distances and reach remote environments, where...
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Modeling external carbon addition in combined N-P activated sludge systems with an extension of the IWA Activated Sludge Models
PublikacjaThe aim of this study was to expand the IWA Activated Sludge Model No. 2d (ASM2d) to account for a newly defined readily biodegradable substrate that can be consumed by polyphosphate accumulating organisms (PAOs) under anoxic and aerobic conditions, but not under anaerobic conditions. The model change was to add a new substrate component and process terms for its use by PAOs and other heterotrophic bacteria under anoxic and aerobic...
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Modeling external carbon addition in combined N-P activated sludge systems with an extension of the IWA Activated Sludge Models
PublikacjaThe aim of this study was to expand the IWA Activated Sludge Model No. 2d (ASM2d) to account for a newly defined readily biodegradable substrate that can be consumed by polyphosphate accumulating organisms (PAOs) under anoxic and aerobic conditions, but not under anaerobic conditions. The model change was to add a new substrate component and process terms for its use by PAOs and other heterotrophic bacteria under anoxic and aerobic...
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As causas do trincamento a frio de um ação submetido a soldagem subaquática
PublikacjaA soldagem subaquàtica usada na confeccao de juntas de acos de alta resistencia aumenta a sua susceptibilidade ao trincamento a frio, um efeito decorrente da transferencia de calor muito mais rapida a partir da area de soldagem e da presenca de hidrogenio difusivel, o que causa aumento da fragilidade do metal. Este trabalho avalia esta propensao ao trincamento a frio do aco S355G10+N usado na construcao de estrururas hidrotecnicas...
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Analysis of the applicability of laser scanning to making an inventory of swimming pool facilities
Publikacja3D scanning can be used in many branches of economy, e.g. reverse and prototype engineering, industrial design, quality control, pros-thetics, orthodontics, archiving of historic objects and archeological findings, examination of a scene of crime, making films and comput-er games. The technology of terrestrial laser scanning has a bright fu-ture as we are living in the time of blooming measurement tech-niques, which can provide...
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Co-Living or a “Sandpit” for Future Entrepreneurs. First Experience from Poland.
PublikacjaNowadays, the Western world seems saturated with the myriad of enhancements for entrepreneurship development. Also, in Eastern European countries we observe a growing number of initiatives at different organizational levels, aiming at accompanying potential future entrepreneurs in their efforts. Meanwhile, there is one novelty, never before offered on the Polish market – the first co- -living space, launched in Gdañsk. Therefore,...
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The Indication Methods and Techniques of Urban Light Pollution
PublikacjaThe goal of this study is to review and categorize approaches and methods of facing urban light pollution. Probing various references and documents, the current practice focus on extracting and reviewing different types of urban light pollution detection, survey, and measurement to define a taxonomy of methods by instant comparison. The means of measurement and detecting this pollution include 14 most cited techniques that have...
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Contaminants in airport runoff water in the Vicinities of Two International Airports in Poland
PublikacjaThe general aim of the study was to evaluate environmental quality associated with the operations (combustion of fuels, cleaning of aircraft and airport aprons, aircraft, ground vehicle maintenance and repairs, fuelling operations, de/anti-icing operations) of international airports located in central and northern of Poland. These two monitoring areas were set up to monitor PAHs, PCBs, formaldehydes, phenols, detergents (cationic,...
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Targeting Spike‐ACE2 Interface of SARS‐CoV‐2 and its Omicron Variant: A Comparative Screening of Potential Inhibitors for Existing and Anticipating Variants Using Molecular Modelling Approach
PublikacjaThe recent COVID pandemic has shown major impact on public health and economic crisis. Despite the development of many vaccines and drugs against the severe acute respiratory syndrome (SARS) coronavirus 2, the pandemic still persists. The continued spread of the virus is largely driven by the emergence of viral variants such as α, β, γ, delta, epsilon spike, omicron and its subvariants (BA.1,2,3) which can evade the current vaccines...
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NADPH Oxidase Gene Polymorphism is Associated with Mortality and Cardiovascular Events in 7-Year Follow-Up
PublikacjaThe CYBA gene encodes the regulatory subunit of NADPH oxidase, which maintains the redox state within cells and in the blood vessels. That led us to investigate the course of coronary artery disease (CAD) with regards to CYBA polymorphisms. Thus, we recruited 1197 subjects with coronary atherosclerosis and observed them during 7-year follow-up. Three CYBA polymorphisms: c.214C>T (rs4673), c.-932G>A (rs9932581), and c.*24G>A (1049255)...
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A new tool for the evaluation of the analytical procedure: Green Analytical Procedure Index
PublikacjaA new means for assessing analytical protocols relating to green analytical chemistry attributes has been developed. The new tool, called GAPI (Green Analytical Procedure Index), evaluates the green character of an entire analytical methodology, from sample collection to final determination, and was created using such tools as the National Environmental Methods Index (NEMI) or Analytical Eco-Scale to provide not only general but...
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Contamination of Arctic Lakes with Persistent Toxic PAH Substances in the NW Part of Wedel Jarlsberg Land (Bellsund, Svalbard)
PublikacjaThe expansion of glacier‐free areas in polar regions favours the appearance of lakes in the non‐glaciated parts of glacier basins. This paper presents the differentiation of organic compound concentrations in fifty‐four Arctic lakes collected in four locations (Logne Valley, in the vicinity of the Scott, Renard and Antonia glaciers). We cover meteorological measurements, chemical analysis of sixteen dioxin‐like compounds (Polycyclic...
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Solid phase microextraction–comprehensive twodimensional gas chromatography–time-of-flight mass spectrometry: a new tool for determining PAHs in airport runoff water samples
Publikacjafundamental aspect of airport operations is the pollution caused by airport runoff waters. Polycyclic aromatic hydrocarbons (PAHs) are one of the most important groups of xenobiotics which are commonly found in runoff water originating from airports. Only very limited data on the analysis of airport runoff water have been published until now. Therefore, a reliable and accurate analytical method based on headspace solid-phase microextraction...
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Wideband Off-Body Channel Characteristics with Dynamic User
PublikacjaThis paper presents the preliminary results of a dynamic off-body channel characterisation study, based on wideband measurements at 5.8 GHz in an indoor environment. The Channel Impulse Response (CIR) was measured for a scenario with the user approaching and departing from the off-body antenna. A CIR deconvolution procedure was performed jointly in two polarisations, and the received signal power, Cross-Polarisation Discrimination...
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[Chapter] 22. Application of physical modeling to study combustion process-es and flow patterns in large-scale boilers and furmaces. W: Optical me- thods and data processing in heat and fluid flow. Ed. C. Greated, J. Cos-grove, J.M. Buick. Bury St. Edmunds. London: Profess. Eng. Publ.**2002 s. 267-277, 4 rys. bibliogr. 6 poz. Zastosowanie modelowania fizycznego do badania procesów spalania pola prze- pływu w przemysłowych kotłach i piecach.
PublikacjaRozdział zawiera wyniki badań modelowania fizycznego dwuwymiarowego i trój-wymiarowego pola przepływu i procesów spalania w wybranych urządzeniachprzemysłowych.
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Influence of nonlinearities on the efficiency and accuracy of FEM calculations on the example of a steel build-up thin-walled column
PublikacjaDue to the increase of computing capabilities of standard processing units, it is possible to perform complex analyses, considering a number of nonlinearities, such as geometric, material and boundary (contact) even on personal computers. In the paper, the authors have analysed the efficiency and accuracy of standard PC’s FEM calculations performed in Abaqus CAE 2017 software on the example of a critical load assessment of a thin-walled...
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Krajobraz wiejski i turystyka. Poszukiwanie równowagi pomiędzy widzeniem i wizerunkiem wsi
PublikacjaNajważniejszym składnikiem marki wsi jest krajobraz. Wizerunek wsi kreowany w turystyce i dostępny widok różnią się jednak coraz bardziej: przekaz reklamowy identyfikuje wieś z przyrodą oraz ciszą i spokojem; wieś realna stanowi, najczęściej dysharmonijną, mozaikę wiejsko-miejskiego zagospodarowania. Konfrontacja dostarczonego przez turystykę komunikatu z oglądanym krajobrazem podważa wiarygodność marki wsi, co stanowi zagrożenie...
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Ocena stanu technicznego konstrukcji zgarniaczy będących na wyposażeniu osadników wstępnych Grupowej Oczyszczalni Ścieków „DĘBOGÓRZE
PublikacjaOsadniki wstępne typu DORRA – 4 szt., o pojemności 1830 m3, wyposażone są w elementy mechaniczne do kierunkowego przemieszczania się osadu w kierunku leja centralnego. Celem pracy jest ocena stany technicznego części mechanicznej, a w szczególności: - konstrukcji zespołu zgarniania części pływających oraz osadu. - zespołu napędu i sterowania, - zespołu napędu i jazdy. Pierwsze dwa zespoły będą oceniane również z punktu widzenia...
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Parallel computations in the volunteer based Comcute system
PublikacjaThe paper presents Comcute which is a novel multi-level implemen- tation of the volunteer based computing paradigm. Comcute was designed to let users donate the computing power of their PCs in a simplified manner, requiring only pointing their web browser at a specific web address and clicking a mouse. The server side appoints several servers to be in charge of execution of particular tasks. Thanks to that the system can survive...
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The New 3D Printed Left Atrial Appendage Closure with a Novel Holdfast Device: A Pre-Clinical Feasibility Animal Study
PublikacjaMany patients undergoing cardiac surgery have risk factors for both atrial fibrillation and stroke. The left atrial appendage (LAA) is the primary site for thrombi formation. Therefore LAA occlusion devices should be tested for their ability to reduce future cerebral ischemic events in patients with high-risk of haemorrhage. The aim of this study was to evaluate the safety and feasibility of a novel left atrial appendage exclusion...
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Acute hypoxia diminishes the relationship between blood pressure and subarachnoid space width oscillations at the human cardiac frequency
PublikacjaAcute hypoxia exerts strong effects on the cardiovascular system. Heart-generated pulsatile cerebrospinal fluid motion is recognised as a key factor ensuring brain homeostasis. We aimed to assess changes in heart-generated coupling between blood pressure and subarachnoid space width oscillations during hypoxic exposure.
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Cancer-selective, single agent chemoradiosensitising gold nanoparticles
PublikacjaTwo nanometre gold nanoparticles (AuNPs), bearing sugar moieties and/or thiol-polyethylene glycol-amine (PEG-amine), were synthesised and evaluated for their in vitro toxicity and ability to radiosensitise cells with 220 kV and 6 MV X-rays, using four cell lines representing normal and cancerous skin and breast tissues. Acute 3 h exposure of cells to AuNPs, bearing PEG-amine only or a 50:50 ratio of alpha-galactose derivative and...
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Assessment of the Relationship between the Shape of the Lateral Meniscus and the Risk of Extrusion Based on MRI Examination of the Knee Joint
PublikacjaBackground Meniscus extrusion is a serious and relatively frequent clinical problem. For this reason the role of different risk factors for this pathology is still the subject of debate. The goal of this study was to verify the results of previous theoretical work, based on the mathematical models, regarding a relationship between the cross-section shape of the meniscus and the risk of its extrusion. Materials and Methods Knee...
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The Influence of Articular Cartilage Thickness Reduction on Meniscus Biomechanics
PublikacjaObjective Evaluation of the biomechanical interaction between meniscus and cartilage in medial compartment knee osteoarthritis. Methods The finite element method was used to simulate knee joint contact mechanics. Three knee models were created on the basis of knee geometry from the Open Knee project. We reduced the thickness of medial cartilages in the intact knee model by approximately 50% to obtain a medial knee osteoarthritis...
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Mass spectrometry based identification of geometric isomers during metabolic stability study of a new cytotoxic sulfonamide derivatives supported by quantitative structure-retention relationships
PublikacjaA set of 15 new sulphonamide derivatives, presenting antitumor activity have been subjected to a metabolic stability study. The results showed that besides products of biotransformation, some additional peaks occurred in chromatograms. Tandem mass spectrometry revealed the same mass and fragmentation pathway, suggesting that geometric isomerization occurred. Thus, to support this hypothesis, quantitative structure-retention relationships...
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Molecular Recognition in Complexes of TRF Proteins with Telomeric DNA
PublikacjaTelomeres are specialized nucleoprotein assemblies that protect the ends of linear chromosomes. In humans and many other species, telomeres consist of tandem TTAGGG repeats bound by a protein complex known as shelterin that remodels telomeric DNA into a protective loop structure and regulates telomere homeostasis. Shelterin recognizes telomeric repeats through its two major components known as Telomere Repeat-Binding Factors, TRF1...