Search
Filters
total: 6815
filtered: 1528
displaying 1000 best results Help
Search results for: INTER-CELL INTERFERENCE
-
ICT-enabled circular economy: conceptualising the links
PublicationThis chapter sets conceptual backgrounds regarding the potentially emerging causal links between digital technologies and circular economy ideas implementation. We argue that digital technologies may constitute an effective element enabling the transformation from linear to circular and environmentally friendly economic activities. This work draws the general picture at the macro and micro level. The macro perspective shows how...
-
Public Finance in Poland in a COVID Fog: A Look Through the Lens of Fiscal Transparency and Accountability
PublicationAbstract. Goal– The aim of the article is to identify dysfunctional phenomena (implementation of specific mechanisms/solutions and actions taken), generating increased opacity and limit the responsibility/accountability of public f inance in Poland, exacerbated by the COVID-19 crisis. Methods– descriptive analysis, comparative analysis and financial analysis methods were used. Results– fiscal transparency and accountability in...
-
CeIr3: superconductivity in a phase based on tetragonally close packed clusters
PublicationWe present the crystallographic analysis, superconducting and spectroscopic characterization, and theoretical modeling of CeIr3. Lattice parameters a = 5.2945(1) Å and c = 26.219(1) Å are found for the R-3m symmetry crystal structure, which are close to the literature values. CeIr3 is a moderate type-II superconductor (κ GL = 17, λ e–p = 0.65) below 2.5 K. Ce ions exhibit a strongly intermediate valence character as evidenced by...
-
Synthesis and steroid sulfatase inhibitory activities of N-alkanoyl tyramine phosphates and thiophosphates
PublicationA series of phosphate and thiophosphate analogs based on the frameworks of N-alkanoyl tyramines have been synthesized and biologically evaluated. Their binding modes have been modeled using docking techniques. The inhibitory effects of the synthesized compounds were tested on STS isolated from the human placenta as well as the MCF-7, MDA-MB-231 and SkBr3 cancer cell lines. Most of the new STS inhibitors possessed potent activity...
-
Auxetic foams
PublicationThis paper presents a method of producing auxetic polyurethane foams (PUFs) and their unique properties. The experience was based on a synthesis of traditional flexible polyurethane foam and thermal conversion to auxetic foam. The foam specimens were transformed from conventional Poisson's ratio to auxetic (negative Poisson's ratio) [1]. Basic research was performed to determine the mechanical properties and cell structure. Auxetic...
-
Biological and antibacterial properties of chitosan-based coatings with AgNPs and CuNPs obtained on oxidized Ti13Zr13Nb titanium alloy
PublicationDespite numerous studies, the antibacterial efficiency and cytotoxicity of chitosan-based coatings with nanometals need further studies. The purpose of this research was to determine the biological properties of chitosan coatings implemented with either silver nanoparticles (AgNPs) or copper nanoparticles (CuNPs), that were electrophoretically deposited on electrochemically oxidized Ti13Zr13Nb alloy. The SEM tests were used to...
-
Effectiveness of a dual surface modification of metallic interconnects for application in energy conversion devices
PublicationA dual surface modification of an SOFC metallic interconnect with a Gd2O3 layer and an MnCo2O4 coating was evaluated. The tested samples were oxidized for 7000 h in air at 1073 K. Oxidation products were characterized using XRD, SEM-EDS, and confocal Raman imaging, and ASR was measured. The effect of gadolinium segregation at grain boundaries in Cr2O3 was evaluated using S/TEM-EDS. Area specific-resistance was measured and fuel...
-
Therapeutic intervention by the simultaneous inhibition of DNA repair and type I or type II DNA topoisomerases: one strategy, many outcomes
PublicationMany anticancer drugs reduce the integrity of DNA, forming strand breaks. This can cause mutations and cancer or cell death if the lesions are not repaired. Interestingly, DNA repair-deficient cancer cells (e.g., those with BRCA1/2 mutations) have been shown to exhibit increased sensitivity to chemotherapy. Based on this observation, a new therapeutic approach termed 'synthetic lethality' has been developed, in which radiation...
-
Light intensity analysis of photovoltaic parameters for perovskite solar cells
PublicationThe number of publications on perovskite solar cells (PSC) continues to grow exponentially. Although the efficiency of PSC is exceeded 25.5%, not every research laboratory can reproduce this result or even pass the border of 20%. Unfortunately, it is not always clear which dominating mechanism is responsible for the performance drop. Here, we develop a simple method of light intensity analysis of JV parameters allowing the understanding...
-
Photovoltaic effect in the single-junction DBP/PTCBI organic system under low intensity of monochromatic light
PublicationPhotoelectric properties of the planar ITO/MoO3/DBP/PTCBI/BCP/Ag system were characterized on the basis of short-circuit current, open-circuit voltage and absorption spectra, and current-voltage measurements in the dark and under monochromatic illumination of low intensity. Photovoltaic performance of the system was compared with the performance of ideal semiconductor and excitonic cells of chosen bandgaps. Such analysis shows,...
-
Wczesne wykrywanie spoofingu GNSS typu carry-off
PublicationW referacie przedstawiono klasyfikację ataków typu spoofing ukierunkowanych na odbiorniki satelitarnych systemów nawigacyjnych GNSS. W szczególności opisano zaawansowaną formę spoofingu w wariancie tzw. carry-off, polegającym na płynnym przejęciu kontroli nad blokami śledzenia sygnałów w zakłócanym odbiorniku. Sposób realizacji takiego ataku istotnie utrudnia jego wykrycie z użyciem metod dotychczas proponowanych w literaturze....
-
Synthesis, crystal structure and cytotoxic activity of ruthenium(II) piano-stool complex with N,N-chelating ligand
PublicationA mononuclear compound of the general formula [(η6-p-cymene)RuIICl(2,2′-PyBIm)]PF6 has been synthesized from a bidentate N,N-donor ligand, viz. 2,-(2′-pyridyl)benzimidazole (2,2′-PyBIm) and the corresponding chloro-complex [(η6-p-cymene)Ru(μ-Cl)Cl]2 (precursor). The isolated coordination compound was characterized by IR, UV–vis and 1H, 13C NMR spectroscopies. The single crystal X-ray analysis of the complex reveals that the asymmetric...
-
Green energy extraction for sustainable development: A novel MPPT technique for hybrid PV-TEG system
PublicationThe Photovoltaic (PV) module converts only a small portion of irradiance into electrical energy. Most of the solar energy is wasted as heat, resulting in a rise in PV cell temperature and a decrease in solar cell efficiency. One way to harvest this freely available solar thermal energy and improve PV cell efficiency is by integrating PV systems with thermoelectric generators (TEG). This cogeneration approach of the hybrid PV-TEG...
-
Electrochemical Production of Sodium Hypochlorite from Salty Wastewater Using a Flow-by Porous Graphite Electrode
PublicationThe production of sodium hypochlorite (NaOCl) from salty wastewater using an electrochemical cell has several advantages over other methods that often require hazardous chemicals and generate toxic waste, being more sustainable and environmentally friendly. However, the process of producing sodium hypochlorite using an electrochemical cell requires careful control of the operating conditions, such as the current density, flow rate,...
-
Interactions between bioactive components determine antioxidant, cytotoxic and nutrigenomic activity of cocoa powder extract
PublicationNumerous studies have shown, rather disappointingly, that isolated bioactive phytochemicals are not as biologically effective as natural plant products. Such a discrepancy may be explained by the concept of food synergy, which was verified in this research for cocoa extract versus its major components with regard to cancer chemoprevention. The evaluation embraced the relationship between redox properties evaluated in cell-free systems...
-
Drug-drug interaction potential of antitumor acridine agent C-1748: The substrate of UDP-glucuronosyltransferases 2B7, 2B17 and the inhibitor of 1A9 and 2B7
PublicationBackground The compound 9-(2′-hydroxyethylamino)-4-methyl-1-nitroacridine (C-1748), the promising antitumor agent developed in our laboratory was determined to undergo phase I metabolic pathways. The present studies aimed to know its biotransformation with phase II enzymes – UDP-glucuronosyltransferases (UGTs) and its potential to be engaged in drug-drug interactions arising from the modulation of UGT activity. Methods UGT-mediated...
-
Anticancer Properties of Amino Acid and Peptide Derivatives of Mycophenolic Acid
PublicationBackground: Although Mycophenolic Acid (MPA) is applied as prodrugs in clinic as an immunosuppressant, it also possesses anticancer activity. MPA acts as Inosine-5’-Monophosphate Dehydrogenase (IMPDH) inhibitor, where the carboxylic group at the end of the side chain interacts with Ser 276 of the enzyme via hydrogen bonds. Therefore, MPA derivatives with other polar groups indicated high inhibition too. On the other hand, potent...
-
Pharmaceutical applications of surfactants
PublicationIn this study we focused on biological activity of various surfactants. According to our research, they con act both as carriers as well as therapeutic agents. Depending on their concentration, they can create different structures in a solution, which influence their properties. Liposomes have a significant role in drug delivery system. Surfactants in from of bilayer are analogous to natural biological cell membrane.
-
On the effective properties of foams in the framework of the couple stress theory
PublicationIn the framework of the couple stress theory, we discuss the effective elastic properties of a metal open-cell foam. In this theory, we have the couple stress tensor, but the microrotations are fully described by displacements. To this end, we performed calculations for a representative volume element which give the matrices of elastic moduli relating stress and stress tensors with strain and microcurvature tensors.
-
Sequence variants of p21 gene of the MRL/MpJ mouse: a possible association with the deficit of p21 protein and regenerative phenotype.
PublicationThe MRL/MpJ mouse is known for its enhanced regeneration abilities that manifested themselves by scarless ear-hole wound closure. The deficit of p21 found in the MRL is associated with the regenerative capacity as the p21 gene knockout in a mouse strain unrelated to the MRL mouse results in an ear-hole closure effect, similar to that observed in the MRL mouse. Cdkn1a gene encodes p21 protein, a cyclin-dependent kinase inhibitor,...
-
EKOSYSTEM PRZESTRZENI ZAMIESZKIWANIA W UJĘCIU AUTORSKICH POSZUKIWAŃ FORMY DOMU OPARTYCH O KONCEPCJĘ ZGODNOŚCI
PublicationCelem artykułu jest prezentacja efektów projektu autorskiego realizowanego w oparciu o koncepcję zgodności. Przeprowadzone zostały kilkuletnie studia lokalnych uwarunkowań przyrodniczych skutkujących powstaniem zbioru rysunków i rzeźb oraz fotografii dokumentujących ich aranżację in situ. Badania prowadzono na terenie Pojezierza Kaszubskiego w obszarze południowego brzegu Jeziora Wdzydzkiego. Działania artystyczno-projektowe o...
-
New conjugates of tuftsin and muramyl dipeptide as stimulators of human monocytes-derived dendritic cells
PublicationMuramyl dipeptide (MDP) and tuftsin are known biologically active compound displaying a significant influence on various cell populations of innate immune response. MDP, as a fragment of bacterial cell wall, stimulates not only macrophages and monocytes, but also dendritic cells. In contrast, little is known about tuftsin influence on these cells. Therefore it seemed vital to access whether tuftsin or its derivatives conjugated...
-
Solid Phase Synthesis and Biological Activity of Tuftsin Conjugates
PublicationNew tuftsin/retro-tuftsin conjugates were designed and synthesized using a classical fluorenylmethoxycarbonyl (Fmoc) solid phase procedure. All the peptide conjugates were divided into three series: 1,4-dihydroxyanthraquinone (type A), 1-nitroacridine (type B), and 4-carboxyacridone (type C) derivatives. In type A conjugates, the N-terminal group of the peptide chain is directly connected to the anthraquinone ring at C1 (Scheme...
-
Structure, Mechanical, Thermal and Fire Behavior Assessments of Environmentally Friendly Crude Glycerol-Based Rigid Polyisocyanurate Foams
PublicationIn this work, rigid polyisocyanurate foams were prepared at partial substitution (0–70 wt%) of commercially available petrochemical polyol, with previously synthesized biopolyol based on crude glycerol and castor oil. Influence of the biopolyol content on morphology, chemical structure, static and dynamic mechanical properties, thermal insulation properties, thermal stability and flammability was investigated. Incorporation of...
-
Marine polymers in tissue bioprinting: Current achievements and challenges
PublicationBioprinting has a critical role in tissue engineering, allowing the creation of sophisticated cellular scaffolds with high resolution, shape fidelity, and cell viability. Achieving these parameters remains a challenge, necessitating bioinks that are biocompatible, printable, and biodegradable. This review highlights the potential of marine-derived polymers and crosslinking techniques including mammalian collagen and gelatin along...
-
Buck-Boost Inverters with Symmetrical Passive Four-terminal Networks
PublicationAlternating Voltage Inverters (Converters) supplied by low-voltage sources DC (ex. fuel cell, photovoltaic cell) are most frequently realized on the basis of the three fundamental topologies: a) PWM voltage inverter with boost-converter" system, b) PWM voltage inverter with transformed converter DC/DC in the ,,boost-converter" system, c) PWM current converter. However none of these solutions is claimed to be the best and dominant...
-
Enhanced Toxicity of Bisphenols Together with UV Filters in Water: Identification of Synergy and Antagonism in Three-Component Mixtures
PublicationContaminants of emerging concern (CEC) localize in the biome in variable combinations of complex mixtures that are often environmentally persistent, bioaccumulate and biomagnify, prompting a need for extensive monitoring. Many cosmetics include UV filters that are listed as CECs, such as benzophenone derivatives (oxybenzone, OXYB), cinnamates (2-ethylhexyl 4-methoxycinnamate, EMC) and camphor derivatives (4-methylbenzylidene-camphor,...
-
An Optimized Ka-Band Low Profile Dual-Polarized Transmitarray Antenna With 2D Beam Switching
PublicationThis article presents an optimized dual-polarized transmitarray antenna (TA) designed for MIMO applications at the Ka-band, capable of switching beams in two directions. The antenna aperture uses a small unit cell with three layers of Taconic RF-35 dielectric substrates, which can be easily fabricated using PCB technology. The unit cell achieved a 360-degree phase shift and a transmission magnitude exceeding –0.4 dB at 28 GHz....
-
Electronic structure of intertwined kagome, honeycomb, and triangular sublattices of the intermetallics MCo2Al9 ( M = Sr, Ba)
PublicationIntermetallics are an important playground to stabilize a large variety of physical phenomena, arising from their complex crystal structure. The ease of their chemical tunabilty makes them suitable platforms to realize targeted electronic properties starting from the symmetries hidden in their unit cell. Here, we investigate the family of the recently discovered intermetallics MCo2Al9 (M=Sr, Ba) and we unveil their electronic structure....
-
Growth inhibition of cultured cancer cells by Ribes nigrum leaf extract
PublicationThe present article includes data on the possible selective cytotoxic effect of extract of Ribes nigrum L. growing at high Armenian landscape. For this purpose, different non-cancer (microglial BV-2 wild type (Wt), acyl-CoA oxidase 1 (ACOX1) deficient (Acox1-/-) and cancer (human colon adenocarcinoma HT29 and human breast cancer MCF7) cell lines were applied. R. nigrum leaf ethanol extract showed a growth inhibition effect towards...
-
Featuring Semitransparent p–i–n Perovskite Solar Cells for High-Efficiency Four-Terminal/Silicon Tandem Solar Cells
PublicationTwo issues need to be resolved when fabricating p–i–n semitransparent perovskite solar cells (ST-PVSCs) for four-terminal (4 T) perovskite/silicon tandem solar cells: 1) damage to the underlying absorber (MAPbI3), electron transporting layer ([6,6]-phenyl-C61-butyric acid methyl ester, PCBM), and work function (WF) modifier (polyethylenimine, PEI), resulting from the harsh sputtering conditions for the transparent electrodes (TEs)...
-
Utilizing Genome-Wide mRNA Profiling to Identify the Cytotoxic Chemotherapeutic Mechanism of Triazoloacridone C-1305 as Direct Microtubule Stabilization
PublicationRational drug design and in vitro pharmacology profiling constitute the gold standard in drug development pipelines. Problems arise, however, because this process is often dicult due to limited information regarding the complete identification of a molecule’s biological activities. The increasing aordability of genome-wide next-generation technologies now provides an excellent opportunity to understand a compound’s diverse eects...
-
Synthesis and Cholinesterase Inhibitory Activity of N-Phosphorylated /N-Tiophosphorylated Tacrine
PublicationNovel phosphorus and thiophosphorus tacrine derivatives were designed, synthesized and their biological activity and molecular modeling was investigated as a new potential anti-Alzheimer's disease (AD) agents. All new synthesized compound exhibited lower toxicity against neuroblastoma cell line (SH-SY5Y) in comparison with tacrine. Two analogues in the series, 7 and 9, demonstrated lack of cytotoxicity against hepatocellular cells...
-
Effect Of Resveratrol And Quercetin On Telomerase Regulation In Cancer Cells And Their Anti-Cancer Potential
PublicationTelomeres and telomerase are nowadays one on targets for anticancer therapy. Telomerase is expressed in ~90% of human cancer cell lines and tumor specimens, whereas its enzymatic activity is not detectable in most human somatic cells. Was found that some dietary compounds can modulate telomerase activity in cancer cells. This review summarizes the current knowledge about the effects of resveratrol and quercetin on telomerase regulation...
-
Programmable dynamically changing RC model for evaluation of Dynamic EIS methods and instrumentation
PublicationThe paper concerns the RC equivalent circuit of electrochemical cell with the impedance changed during the experiment. The model was constructed using the digital potentiometers controlled by the microcontroller. This solution allows to control the model impedance by the software means. By creating adequate changes of the impedance spectrum as a time function, the different impedance measurement method can be tested to find out...
-
Application of a catalytic combustion sensor (Pellistor) for the monitoring of the explosiveness of a hydrogen-air mixture in the upper explosive limit range
PublicationA new technique is presented for continuous measurements of hydrogen contamination by air in the upper explosive limit range. It is based on the application of a catalytic combustion sensor placed in a cell through which the tested sample passes. The air content is the function of the quantity of formed heat during catalytic combustion of hydrogen inside the sensor. There is the possibility of using the method in industrial installations...
-
Elektroniczne instrumenty komunikacji marketingowej w marketingu usług medycznych
PublicationNie ma wątpliwości, że wielu polskich świadczeniodawców usług zdrowotnych korzysta z Internetu do komunikowania się z pacjentami. Jednocześnie chcą oni stworzyć wizerunek marki jako bardziej nowoczesnej i atrakcyjnej. Elektroniczna komunikacja marketingowa (szczególnie serwisy informacyjne, serwisy społecznościowe, blogi, fora, microblogi, wyszukiwarki, marketing mobilny) ma coraz większe znaczenie w marketingu usług medycznych,...
-
Analysis of electromagnetic disturbances in DC network of grid connected building-integrated photovoltaic system
PublicationThis paper focuses on conducted electromagnetic interference (EMI) emissions and propagation in the DC network of grid connected building integrated photovoltaic (PV) system. The investigated PV system, consists of ten solar panels, cabling and the grid-connected one phase inverter. The EMI simulation model of the real PV system has been developed with the aid of impedance analyzer measurements of solar panels and the DC network...
-
Application of Thin ZnO ALD Layers in Fiber-Optic Fabry-Pérot Sensing Interferometers
PublicationIn this paper we investigated the response of a fiber-optic Fabry-Pérot sensing interferometer with thin ZnO layers deposited on the end faces of the optical fibers forming the cavity. Standard telecommunication single-mode optical fiber (SMF-28) segments were used with the thin ZnO layers deposited by Atomic Layer Deposition (ALD). Measurements were performed with the interferometer illuminated by two broadband sources operating...
-
Common-Mode Voltage and Bearing Currents in PWM Inverters: Causes, Effects and Prevention
PublicationIn modern induction motor drives an increase of transistors' switching frequency and a decrease of switching times are the sources of some serious problems. The high dv/dt and the common mode voltage generated by the inverter PWM control results in the appearances of bearing currents, shaft voltages, motor terminal overvoltages, the decrease of motor efficiency, and electromagnetic interference. The aspects of common mode (CM)...
-
Design and Characterization of a Planar Structure Wideband Millimeter-Wave Antenna with Wide Beamwidth for Wearable off-body Communication Applications
PublicationThis letter presents the design of a planar single-layer wideband antenna featuring wide beamwidth has well as high and stable in-band gain. The proposed antenna is a planar monopole fed by a bottom-grounded coplanar waveguide to realize wide beamwidth in both the xz- and yz-planes. Simultaneous optimization of all adjustable antenna parameters, carried out at the full-wave electromagnetic simulation level. The constructive interference...
-
Electron collisions with cyanoacetylene HC3N : Vibrational excitation and dissociative electron attachment
PublicationWe experimentally probe electron collisions with HC3N in the energy range from 0 to 10 eV with the focus on vibrational excitation and dissociative electron attachment. The vibrational excitation cross sections show a number of resonances which are mode specific: the two dominant π∗ resonances are visible in the excitation of all the vibrational modes; however, broad σ ∗ resonances are visible only in certain bond-stretching vibrational...
-
Study of probe signal bandwidth influence on estimation of coherence bandwidth for underwater acoustic communication channel
PublicationA signal transmitted in a shallow Underwater Acoustic Communication (UAC) channel suffers from time dispersion due to the multipath propagation and the refraction phenomena. This causes intersymbol interference of the received signal and frequency-selective fading observed in its spectrum. Coherence bandwidth is one of the key transmission parameters used for designing the physical layer of a data transmission system to minimise...
-
Information System for Drivers Within the Integrated Traffic Management System - TRISTAR
PublicationAdvanced traveler information systems (ATIS) for drivers are a very important element of modern traffic management. In recent years ITS infrastructure is being developed also in Poland. It allows for delivering to drivers information related to the conditions in the road network through, inter alia, dedicated Variable Message Signs (VMS). Such information enables drivers to take decisions, contributing to improving the efficiency...
-
A taxonomy of challenges to resilient message dissemination in VANETs
PublicationInter-vehicular communications is seen as a promising solution to a number of issues related with public road safety, road congestion management, and infotainment. However, Vehicular Ad-hoc NETworks (VANETs) characterized by high mobility of vehicles and facing a number of other issues related with high frequency wireless communications and network disconnections, encounter major challenges related with reliability of message delivery....
-
Within- and between-firm wage inequalities and trade integration in GVC
PublicationThis paper examines between- (inter) and within- (intra) firm wage inequality using rich employer-employee data for 12 European countries. We confirm that much overall wage inequality is observed within sectors and within occupations. The share of the within- and between-firm components in overall wage inequality varies across countries. We estimate the link between involvement in global value chains (GVCs) and wages differentiating...
-
Gdansk Bay sea bed sounding and classification of its results
PublicationThe main goal of this paper is to describe the results of sounding the Gdansk Bay sea bed by using a SES-2000 Standard parametric sub-bottom profiler. Quality of data obtained during trials depends inter alia on a proper location of transducer array to reduce influence of pitch, roll and heave motions as well as ship self noise (resulting from bubbles due to propeller and flow around hull, vibration generated by main engine and...
-
Strain sequence effect on fatigue life and fracture surface topography of 7075-T651 aluminium alloy
PublicationThe paper studies the effect of strain-loading sequence on fatigue lifetime and fracture surface topographies in 7075-T651 aluminum alloy specimens. Fatigue tests were performed in two ways: (i) constant-amplitude loading and (ii) two series of variable amplitude loading with non-zero mean strain values. The topography of the fatigue fractures was measured over their entire surfaces with the help of an optical confocal measurement...
-
Singlet Exciton Diffusion in Vacuum-Evaporated Films of Amine-Based Materials as Studied by Photocurrent and Photoluminescence Quenching Methods
PublicationThe singlet exciton diffusion lengths are determined by the photoconductivity as well as the luminescence surface quenching technique, in vacuum‐evaporated layers of (4,4′,4″‐tris(N‐(3‐methylphenyl)‐N‐phenylylamino) triphenylamine) (m‐MTDATA), 4,4′,4″‐tris[2‐naphthyl(phenyl)amino] triphenylamine (2TNATA), and N,N′‐diphenyl‐N,N′‐bis(3‐methylphenyl)‐[1,1′‐biphenyl]‐4,4′‐diamine (TPD) which are frequently used for fabrication of electroluminescent...
-
Examples of Taxation on Real Estate Properties as an Long-term Investment Asset. Description of Situation in Selected European Countries
PublicationReal estate properties have become the alternative asset for long-term savings and investments. Such investment however is strictly related to risk inter alia taxation policy. The following article describes and discusses both theoretical and practical aspects of long-term investment taxation imposed on real estate market in selected European countries. The article presents the analyses of the taxes including its functions, mechanisms...