Search results for: 25-hydroxy vitamin d
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The Efficacious Benefit of 25-Hydroxy Vitamin D to Prevent COVID-19: An In-Silico Study Targeting SARS-CoV-2 Spike Protein
PublicationThe environment has rapidly looked at proven specialist task forces in the aftermath of the COVID-19 pandemic to build public health policies and measures to mitigate the effects of emerging coronaviruses. According to the researchers, taking 10 μg of 25-hydroxy vitamin D daily is recommended to keep us safe. There have been several studies recently indicating that there is a reduced risk of contracting Coronavirus by 25-hydroxy...
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Relationships between concentrations of selected organohalogen contaminants and thyroid hormones and vitamins A, E and D in Faroese pilot whales
PublicationPilot whales (Globicephala melas) from the Faroe Islands, North-East Atlantic, have high body concentrations of organohalogenated compounds (OHCs), such as polychlorinated biphenyls (PCBs), organochlorinated pesticides (OCPs) and brominated flame retardants (BFRs). The aim of the present study was to examine if and to what extent blood plasma and liver concentrations of several groups of these OHCs are related to concentrations...
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Genetic Determinants of Vitamin D-Related Disorders; Focus on Vitamin D Receptor
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Vitamin D and Human Health
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Vitamin D signaling and melanoma: role of vitamin D and its receptors in melanoma progression and management
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Practical guidelines for the supplementation of vitamin D and the treatment of deficits in Central Europe — recommended vitamin D intakes in the general population and groups at risk of vitamin D deficiency
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Vitamin D in the skin physiology and pathology.
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Vitamin D Receptor Gene Polymorphism and Vitamin D Status in Population of Patients with Cardiovascular Disease—A Preliminary Study
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Novel vitamin D photoproducts and their precursors in the skin
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Role of Vitamin D in schizophrenia in elderly patient
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New vitamin D analogs as potential therapeutics in melanoma
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Vitamin D receptor(s): In the nucleus but also at membranes?
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Trend research of vitamin D receptor: Bibliometric analysis
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Vitamin D receptor gene polymorphisms in Alzheimer's disease patients
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Vitamin D and its analogs as anticancer and anti-inflammatory agents
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Vitamin D Metabolism Gene Polymorphisms and Their Associated Disorders: A Literature Review
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Differential antitumor effects of vitamin D analogues on colorectal carcinoma in culture
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On the role of classical and novel forms of vitamin D in melanoma progression and management
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Vitamin D derivatives enhance cytotoxic effects of H2O2 or cisplatin on human keratinocytes
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Research Trends of Vitamin D Metabolism Gene Polymorphisms Based on a Bibliometric Investigation
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Seasonal pattern of vitamin D hydroxyl metabolite concentrations and their association with cardiac medications – An observational study
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Antitumor Effects of Vitamin D Analogs on Hamster and Mouse Melanoma Cell Lines in Relation to Melanin Pigmentation
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Bioactive forms of vitamin D selectively stimulate the skin analog of the hypothalamus-pituitary-adrenal axis in human epidermal keratinocytes
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Differences in the Concentration of Vitamin D Metabolites in Plasma Due to the Low-Carbohydrate-High-Fat Diet and the Eastern European Diet—A Pilot Study
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Improvement of Attention, Executive Functions, and Processing Speed in Elderly Women as a Result of Involvement in the Nordic Walking Training Program and Vitamin D Supplementation
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Antiproliferative activity of side-chain truncated vitamin D analogs (PRI-1203 and PRI-1204) against human malignant melanoma cell lines
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Marek Czachor prof. dr hab.
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Paweł Możejko dr hab.
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Zagadnienia tribologiczne w hamulcu silnika hydraulicznego
PublicationPrzedmiotem badań był prototypowy hamulec cierny wielopłytkowy do silnika satelitowego SM-0,6 o teoretycznej objętości roboczej 16,7 cm3/obr. Hamulec ten zbudowany był z 27 tarcz ciernych wykonanych z materiału TOLOX oraz z pakietu sprężyn talerzowych zamontowanych w układzie X. Zablokowanie hamulca następuje w skutek siły docisku pakietu sprężyn talerzowych płytek ciernych co następuje w chwili spadku ciśnienia w komorze tłoka...
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Leszek Ziemczonek dr
PeopleUniversity education 1973-1978 – Nicolaus Copernicus University in Toruń, University of Gdańsk in Gdańsk, Mathematical Physics, M. Sc. 1979 – Diploma of Postgraduate Studies, Pedagogics 1989 – Institute of Physics, Polish Academy of Sciences in Warsaw, Theoretical Physics, Ph. D. 2010-2012 – Diploma of Postgraduate Studies, Mathematics Training: · 09.1983 – Trieste (Italy) – International Centre for Theoretical Physics...
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The comparison of antioxidant properties and nutrigenomic redox-related activities of vitamin C, C-vitamers, and other common ascorbic acid derivatives
PublicationThe term ‘vitamin C’ describes a group of compounds with antiscorbutic activity of L-ascorbic acid (AA). Despite AA’s omnipresence in plant-derived foods, its derivatives have also been successfully implemented in the food industry as antioxidants, including the D-isomers, which lack vitamin C activity. This study aimed to determine the relationship between redox-related activities for five derivatives of AA using electrochemical,...
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Deep eutectic solvents based assay for extraction and determination of zinc in fish and eel samples using FAAS
PublicationA new assay based on effective (high recovery) extraction by means of deep eutectic solvents (DESs) was developed for ppb level determination of zinc in fishes and eel samples. Choline chloride and Phenol in a 1:2 M ratio was selected as optimal DES-based extraction solvent. 8-Hydroxy quinoline was used as a chelating agent for zinc ions. The optimized conditions were found at pH value of 8, ligand concentration of 10 mg/L, THF...
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Measurement of mass flow of viscous liquid through a Cylindrical Orifice under laminar flow (CylOr)
Open Research DataThe data was obtained as part of the project "Measurement of mass flow of viscous liquid through a Cylindrical Orifice under laminar flow (CylOr)", in which flow tests of hydraulic oil through a cylindrical orifice with a thickness of l = 25 mm and a throat b = 0.5 (diameter pipes D = 50 mm, orifice diameter d = 25 mm) on the test stand at the Department...
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Database of the estimations of the numbers of simplices of triangulation of some classical Lie groups
Open Research DataIt is know that any smooth manifold can be triangulated. The number of simplices of triangulation of a given manifold depends on its topological and combinatorial structure. The data consists of the lower bounds for the numbers of simplices of each dimension of any triangulation of classical Lie groups U(n), SU(n), Sp(n), and SO(n) for n up to 25. Each...
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Numeryczna analiza wpływu kierunku rozchodzenia się fali wybuchu na krzywiznę asymetrycznie walcowanego pasma Al-Cu. Numerical analysis the influence of the direction of explosion wave at the curvature of asymmetrical rolling of bimetallic plate.
PublicationW artykule przedstawiono numeryczną analizę wpływu kierunku rozchodzenia się fali wybuchu na krzywiznę asymetrycznie walcowanego pasma Al-Cu. Przeprowadzono symulacje dla procesu walcowania w temperaturze 20 C. Proces walcowania prowadzono w walcarce duo D 150 mm, o prędkości obwodowej 18,5 obr/min. Badania przeprowadzono dla dwóch stosunków grubości warstw 2/10 i 4/8. Symulację procesu przeprowadzono dla trzech gniotów 10%, 20%,...
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A new B-D-galactosidase with a low temperature optimum isolated from the Antarctic Arthrobacter sp. 20B: gene cloning, purification and characterization.
PublicationA psychrotrophic bacterium producing a coldadaptedB-galactosidase upon growth at low temperatureswas classiWed as Arthrobacter sp. 20B. A genomic DNAlibrary of strain 20B introduced into Escherichia coliTOP10F' and screening on X-Gal (5-bromo-4-chloro-3-indolyl-B-D-galactopyranoside)-containing agar plates ledto the isolation of B-galactosidase gene. The B-galactosidasegene (bgaS) encoding a protein of 1,053 amino acids,with a...
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Chemical composition of shells from red (Strongylocentrotus franciscanum) and green (Strongylocentrotus droeba-chiensis) sea urchin
PublicationThe shells from red and green sea urchins accounted for 47.9 and 40.7% of their body weights, respectively. The red and green sea urchin shells contained 91.08 and 90.77% minerals and 4.06 and 4.99% proteins, respectively. The shells did not contain any chitin. Sea urchin shells had a relatively large amount of naphthoquinone pigments, 121 mg per 100 g in red and 163 mg per 100 g in green species. The small quantities of glucosamine...
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Wiktoria Wojnicz dr hab. inż.
PeopleDSc in Mechanics (in the field of Biomechanics) - Lodz Univeristy of Technology, 2019 PhD in Mechanics (in the field of Biomechanics) - Lodz Univeristy of Technology, 2009 (with distinction) List of papers (2009 - ) Wojnicz W., Wittbrodt E., Analysis of muscles' behaviour. Part I. The computational model of muscle. Acta of Bioengineering and Biomechanics, Vol. 11, No.4, 2009, p. 15-21 Wojnicz W., Wittbrodt E., Analysis of...
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A new cold-adapted beta-D-galactosidase from the Antarctic Arthrobacter sp. 32c - gene cloning, overexpression, purification and properties
PublicationThe development of a new cold-active β-D-galactosidases and microorganisms that efficiently ferment lactose is of high biotechnological interest, particularly for lactose removal in milk and dairy products at low temperatures and for cheese whey bioremediation processes with simultaneous bio-ethanol production. In this article, we present a new β-D-galactosidase as a candidate to be applied in the above mentioned biotechnological...
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Mirosław Andrusiewicz prof. dr hab. n. med. i n. o zdr.
PeopleDiplomas, degrees conferred in specific areas ̶ Post-doctoral degree in medical sciences (doctor habilitated) (discipline: medical biology) December 4, 2017; Title of academic achievement: "Analysis of selected genes involved in the control of pathological changes in cells derived from internal female reproductive organs"; Poznan University of Medical Sciences, Faculty of Medicine II; re-viewers: Prof. Katarzyna Ziemnicka,...
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Detection of cellulose production capacity of recombinant Escherichia coli strains BL21(DE3) and AAEC191A
Open Research DataBacteria that form biofilms generate an extracellular matrix (ECM), where cellulose stands out as a key constituent. An approach for assessing microorganisms' cellulose production involves using calcofluor white staining on colonies. In this method, a fluorescent dye (calcofluor-white) is introduced to a stable YESCA substrate composed of casamino acids,...
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The microbial and sensory quality of mackerel hot smoked in mild conditions
PublicationThe quality indices of Atlantic mackerel, hot smoked at core temperature not exceeding 60°C, containing 14–27 g salt and 580–670 g water per kg meat, was determined just after smoking and during storage. The aerobic plate count after smoking, chilling and packing in cardboard boxes was 0–12 cfu/25 cm2of the skin of the smoked fish and 10–240 cfu/g of flesh. It was 1.9 log cycle lower than that in the frozen raw material. At 2°C,...
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Occurrence and levels of polybrominated diphenyl ethers (PBDEs) in house dust and hair samples from Northern Poland; an assessment of human exposure
PublicationPolybrominated diphenyl ethers (PBDEs) are among most ubiquitous compounds to be found in indoor environment and ingestion of household dust is considered an important route of exposure to PBDEs, especially in toddlers and young children. The present work reported concentration levels of PBDE congeners (PBDE-28, -47, -99, -100, -153, -154, -183 and -209) in hair and dust samples from selected households from Northern Poland. The...
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Construction, production and evaluation of the diagnostic utility of a recombinant Toxoplasma gondii chimeric antigen MIC1-MAG1-MIC3
Open Research DataThe intracellular parasite Toxoplasma gondii has the ability to infect a wide range of warm-blooded animals, including humans. Currently, diagnosis of toxoplasmosis is based mainly on the use of the native antigens in enzyme immunoassay which allow for detection of IgG, IgM and IgA antibody classes. However, in some cases the performed studies give...
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Construction, production and evaluation of the diagnostic utility of a recombinant Toxoplasma gondii chimeric antigen MIC1-MAG1-ROP1
Open Research DataThe intracellular parasite Toxoplasma gondii has the ability to infect a wide range of warm-blooded animals, including humans. Currently, diagnosis of toxoplasmosis is based mainly on the use of the native antigens in enzyme immunoassay which allow for detection of IgG, IgM and IgA antibody classes. However, in some cases the performed studies give...
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Construction, production and evaluation of the diagnostic utility of a recombinant Toxoplasma gondii chimeric antigen MIC1-MAG1-AMA1
Open Research DataThe intracellular parasite Toxoplasma gondii has the ability to infect a wide range of warm-blooded animals, including humans. Currently, diagnosis of toxoplasmosis is based mainly on the use of the native antigens in enzyme immunoassay which allow for detection of IgG, IgM and IgA antibody classes. However, in some cases the performed studies give...
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Karol Grębowski dr inż.
PeopleKarol Grębowski (M.Sc.) works as an assistant at the Department of Technical Fundamentals of Architecture Design of the Faculty of Architecture at Gdansk University of Technology. His scientific research deals with dynamic phenomena occurring during the vibration of structures, bridges, and studies the design methodology of the elements forming passive protection system of the vehicles degraded by struck or explosion in the context...
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Protect our right to light
Publication“The struggle for light” is how the Swiss architect Le Corbusier described the history of architecture in 1935. Today, with the skies crowded out by buildings in modern cities, those words should ring in the ears of policymakers and planners. Skyscraper construction is booming. China is the leader, last year completing 88 of the 143 buildings around the world that are taller than 200 metres (see ‘Vertical growth’). As the nation’s...
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Multi-objective optimization of the cavitation generation unit structure of an advanced rotational hydrodynamic cavitation reactor
PublicationHydrodynamic cavitation (HC) has been widely considered a promising technique for industrial-scale process intensifications. The effectiveness of HC is determined by the performance of hydrodynamic cavitation reactors (HCRs). The advanced rotational HCRs (ARHCRs) proposed recently have shown superior performance in various applications, while the research on the structural optimization is still absent. The present study, for the...
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Synthetic, Structural, and Spectroscopic Characterization of a Novel Family of High-Spin Iron(II) [(β-Diketiminate)(phosphanylphosphido)] Complexes
PublicationThis work describes a series of iron(II) phosphanylphosphido complexes. These compounds were obtained by reacting lithiated diphosphanes R2PP(SiMe3)Li (R = t-Bu, i-Pr) with an iron(II) β-diketiminate complex, [LFe(μ2-Cl)2Li(DME)2] (1), where DME = 1,2-dimethoxyethane and L = Dippnacnac (β-diketiminate). While the reaction of 1 with t-Bu2PP(SiMe3)Li yields [LFe(η1-Me3SiPPt- Bu2)] (2), that of 1 with equimolar amounts of i-Pr2PP(SiMe3)Li,...
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Cloning, expression, and biochemical characterization of a coldactive GDSL-esterase of a Pseudomonas sp. S9 isolated from Spitsbergen island soil
PublicationAn estS9 gene, encoding an esterase of the psychrotolerant bacterium Pseudomonas sp. S9 was cloned and sequenced. The deduced sequence revealed a protein of 636 amino acid residues with a molecular mass of 69 kDa.Further amino acid sequence analysis revealed that the EstS9 enzyme contained a G-D-S-L motif centered at a catalytic serine, an N-terminal catalytic domain and a C-terminal autotransporter domain. Two recombinant E. coli...
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The mechanism of internalization study of QDgreen−CD−FA−C−2028 conjugate at IC80 value to cancer (H460, Du-145, and LNCaP) and normal (MRC-5 and PNT1A) cells
Open Research DataThe influence of different endocytosis inhibitors on the internalization of QDgreen−CD−FA−C−2028 conjugate at IC80 value in cancer (H460, Du-145, and LNCaP) and normal (MRC-5 and PNT1A) cells. First, the cells were preincubated with: drug-free medium (no inhibitor), at 4 °C, 5 µM Cytochalasin D, 30 µM Amiloride, 80 µM Dynasore, 25 µM Pitstop 2 and 1.5...
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A High-Efficient Measurement System With Optimization Feature for Prototype CMOS Image Sensors
PublicationIn this paper, a gray-scale CMOS image sensor (CIS) characterization system with an optimization feature has been proposed. By using a very fast and precise control of light intensity, based on the pulsewidth-modulation method, it is avoided to measure the illuminance every time. These features accelerate the multicriteria CIS optimization requiring many thousands of measurements. The system throughput is 2.5 Gb/s, which allows...
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Transcriptomic responses to wounding: meta-analysis of gene expression microarray data
PublicationBackground A vast amount of microarray data on transcriptomic response to injury has been collected so far. We designed the analysis in order to identify the genes displaying significant changes in expression after wounding in different organisms and tissues. This meta-analysis is the first study to compare gene expression profiles in response to wounding in as different tissues as heart, liver, skin, bones, and spinal cord, and...
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New, fast and cheap prediction tests for BRCA1 gene mutations identification in clinical samples.
PublicationDespite significant progress in cancer therapy, cancer is still the second cause of mortality in the world. The necessity to make quick therapeutic decisions forces the development of procedures allowing to obtain a reliable result in a quick and unambiguous manner. Currently, detecting predictive mutations, including BRCA1, is the basis for effectively treating advanced breast cancer. Here, we present new insight on gene mutation...
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Tailoring of SiOC composition as a way to better performing anodes for Li-ion batteries
PublicationPolymer derived silicon oxycarbide (SiOC) ceramics are investigated as potential anodes for lithiumion batteries. Different SiOC ceramics are prepared by pyrolysis (1000 °C and 1400 °C under controlled argon atmosphere) of polysiloxanes ceramic precursors. Preceramic polymers are synthesized using the sol–gel method. Phenyltriethoxysilane (PhTES) and methyltriethoxysilane (MTES) have been used as starting precursors and mixed with...
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Scanning electrochemical micrographs of poly(lactic acid) 3D printed electrodes ablated by femtosecond laser
Open Research DataThe dataset contains the scanning electrochemical micrographs of the femtosecond laser (FSL) ablation at the surface of commercially available carbon black-filled poly(lactic acid) 3D printed electrode. The process is used for the increase of the charge transfer of this electrode in electrochemical studies.
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Unia Europejska i strefa euro : doświadczenia i wyzwania ekonomiczne, techniczne, inżynieryjne : monografia
PublicationAutorzy: Gwóźdź-Lasoń Monika, Miklaszewicz Sławomir,
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The experimental results of diesel fuel spray with marine engine injector
Open Research DataThe data set presents the measurement of the diesel fuel spray from with marine engine injector. The main target presents results is a study of the time course of macro parameters (spray tip penetration, spray cone angle) of fuel spray in the cylinder of marine diesel engine. The impact of ambient conditions and the geometrical parameters of the injector...
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Evaluation of antimicrobial activity of porous composites based on chitosan/poly (vinyl alcohol)
Open Research DataThe dataset contains the results of microbiological tests of composite porous materials whose activity was assessed for their ability to reduce the number of Escherichia coli and Staphylococcus aureus strain, representing the Gram (-) and Gram (+) bacteria, respectively.
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Investigation of low-temperature cracks on selected national roads and motorways in Poland 2020
Open Research DataThe dataset contains video investigation and records of 68 road sections in various parts of Poland. Videos were recorded with the use of two cameras: 1) mounted in front of measurement vehicle, which was focused on overall view of road and 2) which was focused on pavement surface. The records are categorized according to the ID of the section given...
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Stefan Niewitecki dr inż. arch.
PeopleW dniu 29.07.1977 r. ukończenie Studium Podyplomowego Kształcenia Pedagogicznego Nauczycieli Akademickich (świadectwo Nr 301, wynik dobry). Dnia 29.04.1982 r. nagroda III stopnia Rektora Politechniki Gdańskiej, zespołowa za ''Studium wpływu ujęcia wody Gdańsk-Lipce na stateczność obiektów budowlanych w rejonie leja depresyjnego.'' W 1986 r. nagroda Rektora Politechniki Gdańskiej za ''Orzeczenie i projekt techniczny wzmocnienia...
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Strumieniowy generator wirów wzdłużnych - mechanizm działania i zastosowanie do sterowania przepływem
PublicationPraca dotyczy analizy wirów wzdłużnych generowanych przy pomocy strumienia (strugi) wydmuchiwanego do warstwy przyściennej przez otwór w ścianie. Interakcja wypływającego strumienia z przepływem wzdłuż ściany prowadzi do tworzenia się ukierunkowanego wiru, który może być wykorzystany do oddziaływania na strukturę przepływu oraz rozkład naprężeń wzdłuż przepływu za generatorem. Strumieniowe generatory wirów wzdłużnych są alternatywnym...
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Robert Piotrowski dr hab. inż.
PeopleRobert Piotrowski jest absolwentem Wydziału Elektrotechniki i Automatyki (2001r., kierunek: Automatyka i Robotyka) oraz Wydziału Zarządzania i Ekonomii (2002r., kierunek: Organizacja Systemów Produkcyjnych) Politechniki Gdańskiej. Od 2005 roku jest zatrudniony na Wydziale Elektrotechniki i Automatyki, aktualnie w Katedrze Inteligentnych Systemów Sterowania i Wspomagania Decyzji. W 2005 roku obronił rozprawę doktorską (Automatyka...
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Development of Biocompatible Fe3O4@SiO2 Nanoparticles as Subcellular Delivery Platform for Glucosamine-6-phosphate Synthase Inhibitors
PublicationNumerous inhibitors of glucoseamine-6-phophate synthase (GlcN-6-P), the enzyme responsible from catalysis of the first step of metabolic pathway leading to metabolism 5’-diphospho-N-acetyl-D- glucosamine, were reported as effective agents for inhibiting the growth of various fungal pathogens. Among the reported inhibitors,...
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Computer controlled systems - 2022/2023
e-Learning Coursesmateriały wspierające wykład na studiach II stopnia na kierunku ACR pod tytułem komputerowe systemy automatyki 1. Computer system – controlled plant interfacing technique; simple interfacing and with both side acknowledgement; ideas, algorithms, acknowledge passing. 2. Methods of acknowledgement passing: software checking and passing, using interrupt techniques, using readiness checking (ready – wait lines). The best solution...
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CCS-lecture-2023-2024
e-Learning Coursesmateriały wspierające wykład na studiach II stopnia na kierunku ACR pod tytułem komputerowe systemy automatyki 1. Computer system – controlled plant interfacing technique; simple interfacing and with both side acknowledgement; ideas, algorithms, acknowledge passing. 2. Methods of acknowledgement passing: software checking and passing, using interrupt techniques, using readiness checking (ready – wait lines). The best solution optimization...