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Search results for: FUNGI INFECTION
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Radar technique in application of interlayer identification connections
PublicationOne of important issues in pavement construction is to ensure that layers applied directly one on top of the other make up a continuous whole and form an integral construction complex. An appropriate interlayer connection plays here significant role ensuring proper transmission of distortions generated by wheels of vehicles to lower layers and preventing water penetration between the layers. In case of damaged pavements where lack...
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A Method of MOS Evaluation for Video Based Services
PublicationThis paper deals with a method for QoE evaluation for the services transmitting large amount of data perceived by the end user in relatively short time periods, e.g. streaming video in mobile operator...
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Experimental determination of basic mechanical properties of elastomeric polymer
PublicationThere are a lot of different methods of repairing and reinforcing damaged structures, but when it comes to historical buildings and other cultural heritage objects, it is as much about mechanical safety as the aesthetical aspects. Recently, a new and innovative method of repairing damaged structures by filling the cracks with a specially prepared polymer mass has been proposed. This new and innovative technique, known as the Flexible...
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Transport properties of aqueous ionic liquid microemulsions: influence of the anion type and presence of the cosurfactant
PublicationTransport properties, viz. specific conductivity, dynamic viscosity and apparent diffusion coefficients, were measured as a function of water content in aqueous ionic liquid microemulsions containing 1-butyl-3- methylimidazolium hexafluorophosphate, [BMIM][PF6] and bis(trifluoromethanesulphonyl)imide, [BMIM][Tf2N], stabilized by the nonionic surfactant TX-100, or its mixture with a cosurfactant, i.e. butanol. The investigation covered...
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The influence of selenium addition during germination of Brassica seeds on health-promoting potential of sprouts
PublicationThe correlation among selenium uptake, the content of bioactive compounds in sprouts, and biological activities triggered in cultured human cells by sprout extracts was investigated. Seeds of Brassica crops and rye were treated with SeO2 water solution. The selenium levels in sprouts increased from 1.0-4.1 to 53.3-382 μg/g dw with no influence on plant physiology according to the indices used. Neither the composition of glucosinolates...
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Principles and Developments of Solid-Phase Microextraction
PublicationSample preparation has been commonly considered a critical step of the analytical process. In this sense, remarkable efforts have been made to develop efficient sample preparation techniques which could overcome the limitations of conventional approaches. Since its inception in the early 1990’s, solid-phase microextraction (SPME) has become a widespread miniaturized sample preparation technique for extraction and preconcentration...
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T cell Activation Is Driven by an ADP-Dependent Glukosinase Linking Enhanced Glycolysis with Mitochondrial Reactive Oxygen Species Generation
PublicationMitochondria-originating reactive oxygen species control T cell receptor (TCR)-induced gene expression. Here, we show that TCR-triggered activation of ADP-dependent glucokinase (ADPGK), an alternative, glycolytic enzyme typical for Archaea, mediates generation of the oxidative signal. We also show that ADPGK is localized in the endoplasmic reticulum and suggest that its active site protrudes toward the cytosol. The ADPGK-driven...
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Reactive deposition of TiNx layers in a DC-magnetron discharge
PublicationTiNx layers have been deposited in 'balanced mode' and 'unbalanced mode' of a reactive DC-magnetron plasma (carrier gas argon, reactive gas nitrogen) under different conditions. Discharge power and reactive gas flow have been varied. The layers have been examined by X-ray photoelectron spectroscopy (XPS), X-ray reflectometry (XR), and spectroscopic ellipsometry (SE). The results of the layer analyses were combined with plasma investigations...
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The Ellenbogen’s “Matter as Software” Concept for Quantum Computer Implementation: IV. The X@C60 Molecular Building Blocks (MBBs) and Computing System Lifetime Estimation
PublicationThe problem of approximate lifetimes of individual X@C60 MBBs and tip-based nanofabricated quantum computing device systems is discussed under the conservative assumption of single-point failure. A single chemical transformation of the C60 cage into high-energy opened o-C60 isomer which forms the communication canal for the low energy transfer of an X atom from X@C60 MBB to the outside environment was studied. According to the...
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Highly porous nanoberyllium for X-ray beam speckle suppression
PublicationThe speckle suppressor device containing highly porous nanoberyllium is proposed for manipulating with the spatial coherence length and removing undesirable speckle structure during the imaging experiments. We report a special device called the speckle suppressor, which contains the highly porous nanoberyllium plate, compacted from both sides by two beryllium windows. By insertion the speckle suppressor in the X-ray beam it allows...
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Dual-Polarized Wideband Bandpass Metasurface-Based Filter
PublicationThis paper presents a novel metasurface-based bandpass filter. The structure is realized by simply patterning a double-sided AD250 substrate, and does not require any vias or insertion of lumped elements. The top layer is an annular- aperture-array with multiple inner conductors, whereas the bottom layer is a first-order Hilbert-curve array. FEM-based simulation results of the filter are obtained using HFSS. The experimental validation...
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Evaluation of Medical Staff Satisfaction for Workplace Architecture in Temporary COVID-19 Hospital: A Case Study in Gdańsk, Poland
PublicationThis article analyses the architecture that was used in the temporary AmberExpo hospital in Gdańsk, Poland which was installed during the COVID-19 pandemic. The construction of this type of facility is often based on experimental approaches, aimed at caring for patients suffering from an infectious disease in emergency conditions. In order to assess the level of employee satisfaction with the architectural and technical elements...
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Subjective and Objective Quality Evaluation Study of BPL -PLC Wired Medium
PublicationThis paper presents results of research on the effectiveness of bi-directional voice transmission in a 6 kV mine cable network using BPL-PLC (Broadband over Power Line - Power Line Communication) technology. It concerns both emergency cable state (supply outage with cable shorted at both ends) and loaded with distorted current waveforms. The narrowband (0.5 MHz–15 MHz) and broadband (two different modes, frequency range of 3 MHz–7.5...
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Modeling of a Quasi-Resonant DC Link Inverter Dedicated to Common-Mode Voltage and Ground Current Reduction
PublicationIn this paper, the modeling methodology of the AC drive system with a Parallel Quasi-Resonant DC Link Inverter (PQRDCLI) is described. A presented modeling approach is an attractive tool used for the effective evaluation of a common-mode (CM) voltage and grounds current reduction methods. Designed models of inverter, induction machine (IM), and cable are simple, thus the methods for parameter extraction are not complicated. Verification...
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Review of Cybersecurity Assessment Methods: Applicability Perspective
PublicationCybersecurity assessments are crucial in building the assurance that vital cyberassets are effectively protected from threats. Multiple assessment methods have been proposed during the decades of the cybersecurity field. However, a systematic literature search described in this paper reveals that their reviews are practically missing. Thus, the primary objective of this research was to fulfil this gap by comprehensively identifying...
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Design of a compact planar transmission line for miniaturized rat-race coupler with harmonics suppression
PublicationThis paper presents an elegant yet straightforward design procedure for a compact rat-race coupler (RRC) with an extended harmonic suppression. The coupler’s conventional λ/4 transmission lines (TLs) are replaced by a specialized TL that offers significant size reduction and harmonic elimination capabilities in the proposed approach. The design procedure is verified through the theoretical, circuit, and electromagnetic (EM) analyses,...
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Challenges and Possibilities of Deep Eutectic Solvent-Based Membranes
PublicationDeep eutectic solvents (DES) are a category of a new class of solvents that can overcome some of the main drawbacks of typical solvents and ionic liquids (ILs). DES have been widely investigated and applied by the research community in several applications since their invention. Over the past years, the use of DES has been directed to the production of new materials and items for new products and processes. This is the case for...
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Intra-operative biopsy in chronic sinusitis detects pathogenic Escherichia coli that carry fimG/H, fyuA and agn43 genes coding biofilm formation
PublicationThe aim of this study was to investigate whether or not surgical biopsy of sinus tissue in chronic sinusitis, not responsive to treatment, would detect E. coli. We intended to evaluate E. coli virulence genes, therefore dispute the causal role of such an unusual microorganism in chronic sinusitis, as well as consider effective pathogen-targeted therapy. Patients with E. coli isolated by intra-operative puncture biopsy were included...
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Polyurethane based hybrid ciprofloxacin-releasing wound dressings designed for skin engineering purpose
PublicationPurpose Even in the 21st century, chronic wounds still pose a major challenge due to potentially inappropriate treatment options, so the latest wound dressings are hybrid systems that enable clinical management, such as a hybrid of hydrogels, antibiotics and polymers. These wound dressings are mainly used for chronic and complex wounds, which can easily be infected by bacteria. Materials and methods Six Composite Porous Matrices...
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Tworzenie modelu pojęciowego dla zarządzania ryzykiem na przykładzie procesu laminowania w stoczni jachtowej
PublicationCelem artykułu jest zaproponowanie modelu pojęciowego normalizującego kryteria oceny ryzyka w systemie zarządzania jakością w stoczni jachtowej. Zamiarem jest przeprowadzenie analizy danych, pozwalającej wytyczyć zbiory o wysokim, średnim i niskim poziomie istotności dla wszystkich błędów powstających w procesie laminowania. W artykule skoncentrowano się na najważniejszych pojęciach związanych z ryzykiem i kryteriami jego oceny....
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Wybrane metody diagnostyki łożysk silników indukcyjnych oparte o pomiar prądu
PublicationW artykule zawarto przegląd wybranych metod diagnostyki łożysk silnika indukcyjnego, bazujących na pomiarach prądu zasilającego. Jedno z nowych rozwiązań przetwarzania sygnałów zostało zaadaptowane przez autorów do stosowanego przez nich systemu diagnostycznego. Wyniki wstępnych badań symulacyjnych zweryfikowanych badaniami na rzeczywistym obiekcie wskazują, że rozwiązanie to ułatwia diagnozowanie. Autorzy zamierzają prowadzić...
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Opracowanie technologii spawania naprawczego szyn poddźwigowych A120 oraz badania nieniszczące jakości szyn w DCT w Porcie Północnym
PublicationEkspertyza dotyczy realizacji zlecenia związanego z naprawą spoin szyn poddźwigowych na terenie terminalu kontenerowego - Deep Water Terminal (DCT) w Porcie Północnym w Gdańsku. W ramach opracowania: 1. Wykonano badania ultradźwiękowe (UT) i magnetyczno-proszkowe (MT) spoin czołowych szyn poddźwigowych typu A120, według schematu dostarczonego przez firmę SKANSKA S.A. 2. Wykonano analizę wyników badań...
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Wzmocnienie uszkodzonej belki typu T w przęśle wiaduktu drogowego
PublicationW artykule opisano metodę wzmocnienia belki prefabrykowanej typu T dźwigara wiaduktu drogowego uszkodzonej przez pojazd „wozidło”. Beton belki uległ zarysowaniom w wielu miejscach. Wystąpiły też ubytki otuliny strun sprężających. Zaproponowano naprawę i wzmocnienie przez dobetonowanie dodatkowej belki. Podczas naprawy zastosowano balastowanie przęsła w celu wciągnięcia nowego dźwigara do współpracy od ciężaru własnego i sprężenia....
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Imidazoacridinone-dependent lysosomal photodestruction: a pharmacological Trojan horse approach to eradicate multidrug-resistant cancers
PublicationMultidrug resistance (MDR) remains a primary hindrance to curative cancer therapy. Thus, introduction of novel strategies to overcome MDR is of paramount therapeutic significance. Sequestration of chemotherapeutics in lysosomes is an established mechanism of drug resistance. Here, we show that MDR cells display a marked increase in lysosome number. We further demonstrate that imidazoacridinones (IAs), which are cytotoxic fluorochromes,...
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Exhaust gas temperature measurements in diagnostics of turbocharged marine internal combustion engines. Part I. Standard measurements.
PublicationThe article discusses the problem of diagnostic informativeness of exhaust gas temperature measurements in turbocharged marine internal combustion engines. Theoretical principles of the process of exhaust gas flow in turbocharger inlet channels are analysed in its dynamic and energetic aspects. Diagnostic parameters are defined which enable to formulate general evaluation of technical condition of the engine based on standard...
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Comprehensive methodology for Staphylococcus aureus lipidomics by liquid chromatography and quadrupole time-of-flight mass spectrometry
PublicationStaphylococcus aureus is a common pathogen known to cause relatively minor infections as well as severe disorders in humans. Although there is fair amount of published data concerning various aspects of its biology, epidemiology, genetics, etc., there is still a scarce amount of data presenting reliable and thorough investigations regarding high-throughput analysis of total S. aureus lipid content. Therefore, the aim of this study...
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Long-distance quantum communication over noisy networks without long-time quantum memory
PublicationThe problem of sharing entanglement over large distances is crucial for implementations of quantum cryptography. A possible scheme for long-distance entanglement sharing and quantum communication exploits networks whose nodes share Einstein-Podolsky-Rosen (EPR) pairs. In Perseguers et al. [Phys. Rev. A 78, 062324 (2008)] the authors put forward an important isomorphism between storing quantum information in a dimension D and transmission...
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Manganese(III) Promoted Cyclization of N-alkenyl-N-(2-hydroxyethyl) amides to Iso-Oxacepham Potent β-Lactamase Inhibitors
PublicationBackground: β-Lactams are still a subject of interest of organic chemists. The main reason for this interest is due to their application as a chemotherapeutic. β-Lactam antibiotics are still the most commonly used drugs in bacterial infections. Method: Methods using 4-exo-trig radical cyclization leading to β-lactams are an alternative to classical Staudinger`s β-Lactams formation. We prepared N-alkenyl-N-(2-hydroxyethyl)amides...
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Molecular basis and potential activity of HIV-1 reverse transcriptase toward trimethylamine-based compounds
PublicationReverse transcriptase (RT) inhibitors are currently used to treat human immunodeficiency virus (HIV)-1 infections. In this work, novel triethylamine derivatives were designed and studied by rigid and flexible docking and molecular dynamics (MD) approaches. An apo form of HIV-1 RT was also studied by MD simulation to analyze comparative response of protein in ligand-bound and ligand-unbound forms. Among newly designed HIV-1 RT inhibitors,...
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Phylogenetic relationship and antimicrobial resistance in Escherichia coli isolated from the Reda River and the Oliwski Stream, Northern Poland = Lekooporność i przynależność filogenetyczna szczepów Escherichia Coli izolowanych z rzeki Redy i Potoku Oliwskiego
PublicationThe high abundance of fecal bacteria in surface water is usually related to poor agricultural practice, pollution caused by domesticated and wild animals as well as with septic tank failures. Identification of fecal contamination sources seems to be crucial in order to effectively estimate the inherent risk. In this study, the phylogenetic relationship of 30 isolates of E. coli, originated from surface water, was estimated by employing...
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Evaluation of long‑term immunity and protection against T. gondii after immunization with multivalent recombinant chimeric T. gondii proteins
PublicationToxoplasmosis caused by the opportunistic, cosmopolitan protozoan Toxoplasma gondii is one of the most common parasitoses in the world. Although it may prove dangerous or even fatal for immunocompromised individuals, immunoprophylaxis for humans is still nonexistent. Thus, the aim of the current work was to assess the ability of two immunogenic recombinant chimeric T. gondii proteins, SAG2-GRA1-ROP1 (SGR) and SAG1-MIC1-MAG1-GRA2...
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Bovine Serum Albumin – Hydroxyapatite Nanoflowers as Potential Local Drug Delivery System of Ciprofloxacin
PublicationIntroduction: Hybrid nanoflowers are structures consisting of organic (enzymes, proteins, nucleic acids) and inorganic components (mostly metal phosphates) with a flower-like hierarchical structure. Novel hybrid nanoflowers based on bovine serum albumin (BSA) and hydroxyapatite (HA) were obtained and characterized. Study on BSA-HA nanoflowers as potential drug delivery system is reported for the first time. Methods: Embedding ciprofloxacin...
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Pharmaceuticals wastewater treatment via different advanced oxidation processes: Reaction mechanism, operational factors, toxicities, and cost evaluation – A review
PublicationPharmaceuticals comprises different drugs used for treating different infections in human being and animals. The huge quantities of pharmaceuticals used are found to discharge into different water resources and cause different health and environmental problems. The continuous and large-scale discharge of pharmaceuticals increases their persistency which can consequently make them more toxic. The different advanced oxidation processes...
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Cost-Efficient Measurement Platform and Machine-Learning-Based Sensor Calibration for Precise NO2 Pollution Monitoring
PublicationAir quality significantly impacts human health, the environment, and the economy. Precise real-time monitoring of air pollution is crucial for managing associated risks and developing appropriate short- and long-term measures. Nitrogen dioxide (NO2) stands as a common pollutant, with elevated levels posing risks to the human respiratory tract, exacerbating respiratory infections and asthma, and potentially leading to chronic lung...
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Antifungal Activity of Capridine β as a Consequence of Its Biotransformation into Metabolite Affecting Yeast Topoisomerase II Activity
PublicationIn the last few years,increasing importance is attached to problems caused by fungal pathogens. Current methods of preventing fungal infections remain unsatisfactory. There are several antifungal compounds whichare highly effective in some cases, however, they have limitations in usage: Nephrotoxicity and other adverse effects. In addition, the frequent use of available fungistatic drugs promotes drug resistance....
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Mechanical Properties, Microstructure and Surface Quality of Polypropylene Green Composites as a Function of Sunflower Husk Waste Filler Particle Size and Content
PublicationAgricultural waste is a still untapped source of materials that can, in case of proper utilization, significantly improve the sustainability of polymers and their composites. In this work, polymer composites based on isotactic polypropylene were produced incorporating ground sunflower husk in the amount of 10 wt% and 20 wt%. The work’s main objective is to evaluate how preliminary fractioning of this agricultural waste filler affects...
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Experimental and Numerical Investigation of Tensile and Flexural Behavior of Nanoclay Wood-Plastic Composite
PublicationIn this study, the effect of wood powder and nanoclay particle content on composites’ mechanical behavior made with polyethylene matrix has been investigated. The wood flour as a reinforcer made of wood powder was at levels of 30, 40, and 50 wt.%, and additional reinforcement with nanoclay at 0, 1, 3, and 5 wt.%. Furthermore, to make a composite matrix, high-density polyethylene was used at levels of 70, 60, and 50% by weight....
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Molecular mechanism of proton-coupled ligand translocation by the bacterial efflux pump EmrE
PublicationThe current surge in bacterial multi-drug resistance (MDR) is one of the largest challenges to public health, threatening to render ineffective many therapies we rely on for treatment of serious infections. Understanding different factors that contribute to MDR is hence crucial from the global “one health” perspective. In this contribution, we focus on the prototypical broad-selectivity proton-coupled antiporter EmrE, one of the...
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Virulence analysis and antibiotic resistance of Klebsiella pneumoniae isolates from hospitalised patients in Poland
PublicationKlebsiella pneumoniae (KP) is a nosocomial pathogen causing difficult-to-treat infections. The presence of virulence genes and antibiotic resistance of 109 KP isolates from hospitalized patients were investigated. Among them, 68.8% were multi-drug resistant (MDR) and 59.6% produced extended-spectrum beta-lactamases (ESBLs). Metallo-β-lactamases (MBLs) were produced by 22% of isolates (mainly from anus), including 16.5% of isolates...
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Share of the wage factor in national income – selected aspects
PublicationThe aim of this study is to examine changes in the share of the wage factor in national income, in selected EU countries against labour productivity and investment rates reflecting changes in capital-labour relations, indicated by researchers as determinants of change of the share of the wage factor in national income. The scope of the study includes a review of literature devoted to the issue of wage factor share in national income...
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Structure and hyperfine interactions in Bi1−xNdxFeO3 solid solutions prepared by solid-state sintering
PublicationThe series of polycrystalline ceramic powders, Bi1xNdxFeO3 (x = 0.11) was successfully synthesized by mixed oxide method followed by pressureless sintering. X-ray diffraction and Mössbauer spectroscopy were used as complementary methods to study structure and hyperfine interactions of the samples. It was found that with an increase of Nd content, within the range of x = 0.20.3 a structural phase transition from rhombohedral to...
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Economical wood sawing with circular saw blades
PublicationMaterial- and energy-saving belong to the basic requirements which are imposed on the contemporary manufacturing processes. Since realization of those processes gives measurable profits not only economical but also ecological. In case of wood sawing with circular saw blades material- and energy-savings are dependent on total overall set of teeth (theoretical kerf) and teeth position accuracy in relation to the workpiece. Hence,...
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Control of the wind turbine generator
PublicationWind power system consists of two main parts: wind turbine and electrical generator. Wind turbine converts the energy of the flowing air into mechanical energy, next generator converts this energy into electrical energy that is sent to the power system. These two processes should be realized with maximum efficiency and the following requirements for the control system can be formulated: opti-mal wind power conversion, compensation...
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IR-THERMAL IMAGING IN CARDIOSURGERY
PublicationA method for monitoring the state of the myocardium during cardiosurgical interventions based on thermal IR imaging is presented. These methods called Static Thermography and Active Dynamic Thermography (ADT) uses information about distribution of temperature on the surface and an external excitation source to induce thermal transient processes in a tested object. Recording time series of thermograms allows to calculate parametric...
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The Origins of the Concept of Ideology
PublicationThe concept of "ideology" as, firstly, a term that points at non-epistemological conditioning of cognitive processes, and, secondly, as a term which aimed at disclosing the ancillary role of given ideas in regard to specific political interests of certain groups, has long history. Since Francis Bacon's theory of idols modern philosophy endavoured to create a comprehensive classification of systematic cognitive errors which divert...
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Kompleksowa analiza symulacyjna układu napędowego zespołu trakcyjnego
PublicationThe paper describes an approach to comprehensive analysis of traction electric drive. The drivetrain of ED-74 electric unit equipped with four inverter-fed induction motors was modeled in Matlab/Simulink. The model consists of functional blocks as: motors, inverters, drive controllers, filters. Structure and operation of the model was described. Chosen simulation results were presented and discussed. Two methods of modeling the...
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Gentiana asclepiadea exerts antioxidant activity and enhances DNA repair of hydrogen peroxide- and silver nanoparticles-induced DNA damage
PublicationExposure to high levels of different environmental pollutants is known to be associated with induction of DNA damage in humans. Thus DNA repair is of great importance in preventing mutations and contributes crucially to the prevention of cancer. In our study we have focused on quantitative analysis of Gentiana asclepiadea aqueous or methanolic extracts obtained from flower and haulm, their antioxidant potency in ABTS post-column...
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Expression of Deinococcus geothermalis Trehalose Synthase Gene in Escherichia coli and Its Enzymatic Properties
PublicationA novel trehalose synthase gene from Deinococcus geothermalis (DSMZ 11300) containing 1,692 bp reading-frame encoding 564 amino acids was amplified using PCR. The gene was ligated into pET30Ek/LIC vector and expressed after isopropyl alfa-D-thiogalactopyranoside induction in Escherichia coli BL21(DE3)pLysS. The recombinant trehalose synthase (DgeoTreS) containing a His6 tag at the C-terminus was purified by metal affinity chromatography...
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Hydrogen production from ethanol In nitrogen microwave plasma At atmospheric pressure
PublicationHydrogen seems to be one of the most promising alternative energy sources. It is a renewable fuel as it could be produced from e.g. waste or bio-ethanol. Furthermore hydrogen is compatible with fuel cells and is environmentally clean. In contrast to conventional methods of hydrogen production such as water electrolysis or coal gasification we propose a method based on atmospheric pressure microwave plasma. In this paper we present...
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Progress in the post weld residual stress evaluation using Barkhausen effect meter with a novel rotating magnetic field probe
PublicationWe report the progress in post weld residual stress evaluation using Barkhausen effect (BE) meter with rotating magnetic field probe. The novel probe of the BE meter contains two C-core electromagnets and searching coil with ferrite antenna. This meter allows automatic measurements of BE intensity envelopes at different angles of magnetizing field. The full process of measurement at given position of the probe takes about only...