Search results for: TRANSCRIPTOMIC PROFILING - Bridge of Knowledge

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Search results for: TRANSCRIPTOMIC PROFILING

Search results for: TRANSCRIPTOMIC PROFILING

  • Application of Structural Control Systems for the Cables of Cable-Stayed Bridges: State-of-the-Art and State-of-the-Practice

    Publication

    - ARCHIVES OF COMPUTATIONAL METHODS IN ENGINEERING - Year 2021

    Stay cables are one of the key elements of cable-stayed bridges and are characterized by lightweight, low inherent damping, and high flexibility. They are continuously subjected to small-to large-amplitude vibrations due to various types of dynamic loads that may, in the long term, cause fatigue and fracture problems for the cable system, and may eventually compromise the safety of cable-stayed bridges. Thus, several countermeasures...

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  • Labyrynths generators, their properties and practical application in computer games

    this paper presents three basic algorithms for generation of mazes, and many of their modifications and examples showing their practical application in creating random structures that resembles those from the real world. the paper highlights the difference in the labyrinths classes generated by listed algorithms and describes a specific and highly likely to occur shapes that occur in generated mazes. particular attention was paid...

  • Perforating systems in shale gas recovery

    Publication

    Hydraulic fracturing is common method of shale gas recovery. Due to environmental, economical and technological problems many alternative technologies have been developed. One of the most promising group of technologies is based on perforating systems. This paper describes theoretical and practical aspects of best known technologies used to create perforations. New perforating/fracturing technologies which can replace hydraulic fracturing...

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  • History and Perspective of Treatment Wetland in Poland – Part One: Lesson learned

    Early implementation of treatment wetlands under supervision of the researchers from were quite promising. The constructed facilities ensured effective wastewater treatment and sludge dewatering. In the next years a number of treatment wetland s systems were constructed without following the designing principles and left without proper maintenance. In the consequence this lead to unsatisfactory treatment results. Investigations...

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  • Poland: Quality Monitoring of Therapeutic Processes in a Small Treatment Center for Children

    Publication

    This article presents the case of the first ISO 9001:2000-certified small healthcare organization (the Center for Therapy and Rehabilitation) providing therapeutic and rehabilitation services for disabled children in Northern Poland. Elements of the process-oriented healthcare quality system implementation, initial benefits, and the organization's quality system structure and process descriptions are described. Particular attention...

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  • Large Hydrodynamic Thrust Bearings and Their Application in Hydrogenerators

    Publication

    Large hydrodynamic thrust bearings are the bearings which, due to hydrodynamic lubrication, allow large axial load to be transferred from a moving part (shaft) to the stationary part via a thin layer of the lubricant (usually oil), thus providing extremely low friction and practically no wear. Hydrogenerators with vertical shafts are the most important application of large thrust bearings. Main design and scientific problems of...

  • MONTE CARLO MODELING OF OPTICAL SENSOR FOR POST-OPERATIVE FREE FLAP MONITORING

    Publication

    After a preliminary study of the currently employed methods in vitality monitoring of the tissue flaps (TRAM, DIEP, SIEA), a usefulness of optical techniques is discussed. It seems that one of the most promising in monitoring tissue flaps blood flow is a near infrared spectrometry (NIRS). However, a special design of a measurement sensor has to be developed. First, basing on the literature study an optical “window” is characterized....

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  • The main developments of the CSR initiatives in Poland

    Publication

    This short paper outlines the most important documents and initiatives that have appeared in the subject throughout the years within the international institutions, such as United Nations or European Union. It also discusses the ways in which the international CSR initiatives are being incorporated into Polish legislative and organizational system, by providing an outline of the biggest and most active organizations and foundations...

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  • NEW TRENDS IN DEVELOPMENT OF ORC'S FOR MICROPOWER GENERATION

    Publication

    - Year 2014

    In the paper, new trends in development of micropower generation of heat and electricity are presented. New type of CHP for domestic usage is developed in the Institute of Fluid-Flow Machinery PAS and methods of its design are presented. The most promising trends in equipment of ORC cycle for this purpose were discussed. Main attention was focused on micro-heat exchangers design based on micro-channels and micro-jets. In our opinion...

  • Electronic Noses and Electronic Tongues

    Publication

    - Year 2017

    Chapter 7 reports the achievements on the field of artificial senses, such as electronic nose and electronic tongue. It examines multivariate data processing methods and demonstrates a promising potential for rapid routine analysis. Main attention is focused on detailed description of sensor used, construction and principle of operation of these systems. A brief review about the progress in the field of artificial senses and future trends...

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  • The CFD modeling in bioreactor tracer studies

    Publication

    - TASK Quarterly - Year 2007

    W artykule zaprezentowano badania traserowe w bioreaktorach z osadem czynnym. Przedstawiono efekty działania procesu dyspersji na podstawie obliczonych podłużnych profili koncentracji znacznika w komorach osadu czynnego zlokalizowanych na Oczyszczalni Ścieków "Wschód" w Gdańsku. W ramach badań wykonano symulację przepływu substancji nieaktywnej (bazując na pomierzonych profilach stężenia znacznika) stosując jednowymiarowe równanie...

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  • Some remarks on the design of microstrip to coplanar line transformer.

    Publication

    - Year 2004

    Przedyskutowano technikę projektowania transformatora standardu umożliwiającego współpracę linii mikropaskowej i linii koplanarnej. Jako sekcję pośrednią wykorzystano uziemiony falowód koplanarny (conductor backed coplanar waveguide). Dokonano oceny różnych profili sekcji pośredniej w oparciu o szereg symulacji elektromagnetycznych, jak i pomiarów charakterystyk transmisji wykonanych modeli transformatorów.

  • Cellular Effects of Selected Unsymmetrical Bisacridines on the Multicellular Tumor Spheroids of HCT116 Colon and A549 Lung Cancer Cells in Comparison to Monolayer Cultures

    Multicellular tumor spheroids are a good tool for testing new anticancer drugs, including those that may target cancer stem cells (CSCs), which are responsible for cancer progression, metastasis, and recurrence. Therefore, we applied this model in our studies of highly active antitumor unsymmetrical bisacridines (UAs). We investigated the cellular response induced by UAs in 2D and 3D cultures of HCT116 colon and A549 lung cancer...

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  • Morphology, Thermo-Mechanical Properties and Biodegradibility of PCL/PLA Blends Reactively Compatibilized by Different Organic Peroxides

    Publication

    - Materials - Year 2021

    Reactive blending is a promising approach for the sustainable development of bio-based polymer blends and composites, which currently is gaining more and more attention. In this paper, biodegradable blends based on poly(ε-caprolactone) (PCL) and poly(lactic acid) (PLA) were prepared via reactive blending performed in an internal mixer. The PCL and PLA content varied in a ratio of 70/30 and 55/45. Reactive modification of PCL/PLA...

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  • Extracting functional groups of ALLINI to design derivatives of FDA‐approved drugs: Inhibition of HIV‐1 integrase

    HIV‐1 integrase (IN) is crucial for integration of viral DNA into the host genome and a promising target in development of antiretroviral inhibitors. In this work, six new compounds were designed by linking the structures of two different class of HIV‐1 IN inhibitors (active site binders and allosteric IN inhibitors (ALLINIs)). Among newly designed compounds, INRAT10b was found most potent HIV‐1 IN inhibitor considering different...

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  • The luminescence study of LiGa5(1−x)O8:5xCr3+ coumpounds

    Open Research Data

    Infrared luminescent materials have evoked much attention from chemists and material scientists. Although substantial progress is made in materials design, the luminescent mechanism remains ambiguous in the complex structures, presenting major barriers to developing novel infrared luminescent materials. Herein, this study aims to deliberate a complete...

  • PROJEKTOWANIE WIELOWYMIAROWEGO REGULATORA BACKSTEPPING W UKŁADZIE DYNAMICZNEGO POZYCJONOWANIA STATKU

    W komercyjnych systemach dynamicznego pozycjonowania statku, pomimo znacznego wzrostu poziomu automatyzacji, wykorzystywane jest nadal sterowanie typu PID. Poprawę jakości procesu pozycjonowania może umożliwić wykorzystanie bardziej efektywnych algorytmów, oferujących zaawansowane nieliniowe techniki sterowania. W artykule przedstawiono zagadnienie projektowania regulatora pozycji i kursu dla układu dynamicznego pozycjonowania...

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  • REALIZACJA USŁUGI DSR NA PRZYKŁADZIE DOMÓW JEDNORODZINNYCH

    Publication

    W artykule przedstawiono ideę usługi DSR, czyli reakcji strony popytowej, dla odbiorców rozproszonych. Polega ona na zmniejszeniu zapotrzebowania na energię elektryczną lub przesunięcia go w czasie. Wdrożenie usługi może w znaczny sposób wpłynąć na pracę systemu elektroenergetycznego – usługa DSR może wspomóc bilansowanie systemu elektroenergetycznego, a także pozytywnie oddziaływać na jego elastyczność, wydajność oraz stabilność....

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  • Are you the change? Exploring citizen engagement for Smart Sustainable Cities

    e-Learning Courses
    • M. Ciesielska

    The purpose of this course is to explore citizen engagement in the context of smart, sustainable cities, with the goal of providing students with an understanding of the principles and practices involved in urban landscaping. Throughout the course, students will explore key concepts and practical applications across various domains, from understanding the principles of citizen engagement to analyzing the role of digital technologies...

  • Properties of Different Varieties of Durian

    Publication
    • S. Arsa
    • A. Wipatanawin
    • R. Suwapanich
    • O. Makkerdchoo
    • N. Chatsuwan
    • P. Kaewthong
    • P. Pinsirodom
    • R. Taprap
    • R. Haruenkit
    • S. Poovarodom... and 3 others

    - Applied Sciences - Year 2021

    Durian (Durio zibethinus Murr.), like many other exotic, tropical, and conventional fruits, is important in the prevention of different diseases. In this study, the characterization of the main bioactive compounds of the most popular cultivars of durian and their properties are described. The changes in the quality indices of the antioxidant status were determined by CUPRAC, ABTS, FRAP, DPPH, and ORAC assays. The profiling of phytochemicals...

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  • Feasibility Study for Food Intake Tasks Recognition Based on Smart Glasses

    Publication

    - Journal of Medical Imaging and Health Informatics - Year 2015

    In this exploratory study 13 adult test subjects have performed different food intake tasks while wearing a three axis accelerometer mounted at a temple of glasses. Two different algorithms for task recognition have been applied and compared. The retrospective data processing leads to better task recognition results when the frequency range of 50 Hz to 100 Hz is analysed within accelerometer signal recordings. A straightforward...

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  • Sensitivity analysis of thin-walled beams and frames.

    Publication

    Praca zawiera pełen tekst referatu wygloszonego na Konferencji w Wilnie.Referat przedstawia problem numerycznej analizy wrażliwości belek i ramstalowych zbudowanych z bi-symetrycznych profili cienkościennychpoddanych skręceniu lub skręceniu ze zginaniem. Przedstawiono wynikianalizy wrażliwości przemieszczeń i sił wewnętrznych przy zmianiegrubosci półek, sztywności dodatkowych stężeń poprzecznych orazszerokości przewiązek.

  • Static analysis of thin-walled beams and frames with stiffeners.

    Publication

    Praca zawiera pełną treść referatu wygłoszonego na Konferencji w Wilnie.Referat przedstawia problem numerycznej analizy belek i ramstalowych zbudowanych z bi-symetrycznych profili cienkościennychze stężeniami. Wyniki analizy przeprowadzonej według koncepcji superelementu jednowymiarowego porównano z wynikami obliczeń przy zastosowaniu gęstej siatki elementów powłokowych QUAD4 programu MSC NASTRAN.

  • Magdalena Barańska dr

    People

    Academic teacher, vocational advisor, educator. Scientific interests: evolution of the role of the university, vocational and personnel guidance, designing an educational and professional career(career planning), lifelong learning. problems of academic education. Since 2010, I have been working with various institutions providing training, consulting, and educational services. 2013 Ph.D. in social sciences in the field of pedagogy...

  • Emotion Recognition Based on Facial Expressions of Gamers

    This article presents an approach to emotion recognition based on facial expressions of gamers. With application of certain methods crucial features of an analyzed face like eyebrows' shape, eyes and mouth width, height were extracted. Afterwards a group of artificial intelligence methods was applied to classify a given feature set as one of the following emotions: happiness, sadness, anger and fear. The approach presented in this...

  • Dilemmas associated with the implementation of quality management systems in Polish smaller health care units

    Publication

    - Year 2014

    The article presents the considerations and recommendations for the implementation of the process-oriented quality management systems (QMS) in small health care units. As an example, the unit providing services for children with disabilities (therapy and rehabilitation) localized in northern part of Poland have been selected. The essential elements of the implementation of the quality system, taking into account the objectives...

  • Music Recommendation Based on Multidimensional Description and Similarity Measures . Rekomendacja muzyki na podstawie wielowymiarowego wektora cech i miar podobieństwa

    Publication

    This study aims to create an algorithm for assessing the degree to which songs belong to genres defined a priori. Such an algorithm is not aimed at providing unambiguous classification-labelling of songs, but at producing a multidimensional description encompassing all of the defined genres. The algorithm utilized data derived from the most relevant examples belonging to a particular genre of music. For this condition to be met,...

  • Using Physiological Signals for Emotion Recognition

    Publication

    - Year 2013

    Recognizing user’s emotions is the promising area of research in a field of human-computer interaction. It is possible to recognize emotions using facial expression, audio signals, body poses, gestures etc. but physiological signals are very useful in this field because they are spontaneous and not controllable. In this paper a problem of using physiological signals for emotion recognition is presented. The kinds of physiological...

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  • Microscopic traffic simulation models for connected and automated vehicles (CAVs) – state-of-the-art

    Publication
    • P. Gora
    • C. Kartakazas
    • A. Drabicki
    • F. Islam
    • P. Ostaszewski

    - Procedia Computer Science - Year 2020

    Research on connected and automated vehicles (CAVs) has been gaining substantial momentum in recent years. However, thevast amount of literature sources results in a wide range of applied tools and datasets, assumed methodology to investigate thepotential impacts of future CAVs traffic, and, consequently, differences in the obtained findings. This limits the scope of theircomparability and applicability and calls for a proper standardization...

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  • The Conference Report of Why R? Turkey 2022: The First R Conference with Call For Papers in Turkey

    Publication
    • M. Cavus
    • O. Aydin
    • O. Evkaya
    • D. Turfan
    • F. Karadag
    • O. Ozdemir
    • U. Dar
    • D. Bezer

    - R Journal - Year 2022

    Why R? Turkey 2022 was a non-profit conference that aimed to bring Turkish R users together and encourage them to attend the R conferences. The targeted audience of the conference consisted of, data scientists, data analysts, and all R users from academia and industry. The three-day conference, which consisted of several events such as workshops, regular talks, lightning talks, short tutorials, and panels, was free of charge and...

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  • Application of multisine nanoscale impedance microscopy to heterogeneous alloy surface investigations

    In the recent years atomic force microscopy is recognized as valuable tool for investigation of surficial features of construction materials. It concerns, among other things, studies of changes caused by such phenomena as galvanic corrosion, passivation associated with the growth of oxide layers, or sensitization of austenitic steels with the formation of carbide phases. In addition, atomic forcemicroscopy allows easy coupling...

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  • Towards Emotion Acquisition in IT Usability Evaluation Context

    Publication

    - Year 2015

    The paper concerns extension of IT usability studies with automatic analysis of the emotional state of a user. Affect recognition methods and emotion representation models are reviewed and evaluated for applicability in usability testing procedures. Accuracy of emotion recognition, susceptibility to disturbances, independence on human will and interference with usability testing procedures are...

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  • Experiences from operation of various expansion devices in small scale ORC

    Publication

    - Year 2014

    The main aim of this paper was to present various expansion devices for an application in the small scale ORC system. The investigations were carried out in two parallel directions. One direction was to design and construct a device dedicated to the analyzed ORC system. The second direction was to adapt existing expansion devices for the needs of the analyzed ORC system. Four various devices were described and presented together...

  • EvOLAP Graph – Evolution and OLAP-Aware Graph Data Model

    Publication

    - Year 2018

    The objective of this paper is to propose a graph model that would be suitable for providing OLAP features on graph databases. The included features allow for a multidimensional and multilevel view on data and support analytical queries on operational and historical graph data. In contrast to many existing approaches tailored for static graphs, the paper addresses the issue for the changing graph schema. The model, named Evolution...

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  • Poly-L-Lysine-modified boron-doped diamond electrodes for the amperometric detection of nucleic acid bases

    Publication

    - JOURNAL OF ELECTROANALYTICAL CHEMISTRY - Year 2015

    Boron-doped diamond (BDD) is a very promising supporting material used in the construction of biosensors for molecular recognition. The direct immobilization of structurally-organized huge molecules, such as poly-L-Lysine (PLL) provides the possibility of determining organic molecules, e.g. nucleic acid bases (e.g. adenine, guanine) or peptides and proteins. This paper describes the direct method for chemical and electrochemical...

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  • GENDER INEQUALITY IN THE LABOUR MARKET IN KAZAKHSTAN AND UZBEKISTAN

    Publication

    - Year 2024

    The aim of the following article is to present gender inequality in the labour market in Kazakhstan and Uzbekistan. Gender inequality was researched by analyzing documents providing rights for women and men in Kazakhstan and Uzbekistan. The author presented the unequal treatment of women in the labour market by examining the causes of the level of employment of women and men - contract workers, higher unemployment among women,...

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  • Green engineered biomaterials for bone repair and regeneration: Printing technologies and fracture analysis

    Publication

    - CHEMICAL ENGINEERING JOURNAL - Year 2024

    Despite the exceptional self-regeneration properties of bone, severe injuries often require additional surgical intervention such as using artificial bone constructs. These structures need to meet a number of criteria regarding their structure, performance, alongside the rate and the mechanism of erosion and fracture when implanted, for stimulating the regeneration of defected bone and, more critically providing support in the...

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  • Molecularly imprinted polymers for the detection of volatile biomarkers

    Publication

    - TRAC-TRENDS IN ANALYTICAL CHEMISTRY - Year 2024

    In the field of cancer detection, the development of affordable, quick, and user-friendly sensors capable of detecting various cancer biomarkers, including those for lung cancer (LC), holds utmost significance. Sensors are expected to play a crucial role in the early-stage diagnosis of various diseases. Among the range of options, sensors emerge as particularly appealing for the diagnosis of various diseases, owing to their cost-effectiveness,...

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  • Cu-HKUST-1 and Hydroxyapatite–The Interface of Two Worlds toward the Design of Functional Materials Dedicated to Bone Tissue Regeneration

    Publication
    • M. Fandzloch
    • W. Bodylska
    • J. Trzcińska-Wencel
    • P. Golińska
    • K. Roszek
    • J. Wiśniewska
    • M. Bartmański
    • A. Lewińska
    • A. Jaromin

    - ACS Biomaterials Science & Engineering - Year 2023

    A novel composite based on biocompatible hydroxyapatite (HA) nanoparticles and Cu-HKUST-1 (Cu-HKUST-1@HA) has been prepared following a layer-by-layer strategy. Cu-HKUST-1 was carefully selected from a group of four Cu-based metal−organic frameworks as the material with the most promising antimicrobial activity. The formation of a colloidal Cu- HKUST-1 layer on HA nanoparticles was confirmed by various techniques, e.g., infrared...

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  • Experimental certification of more than one bit of quantum randomness in the two inputs and two outputs scenario

    Publication

    - NEW JOURNAL OF PHYSICS - Year 2023

    One of the striking properties of quantum mechanics is the occurrence of the Bell-type non-locality. They are a fundamental feature of the theory that allows two parties that share an entangled quantum system to observe correlations stronger than possible in classical physics. In addition to their theoretical significance, non-local correlations have practical applications, such as device-independent randomness generation, providing...

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  • Comparison of 2D and 3D culture models in the studies of the biological response induced by unsymmetrical bisacridines in cancer cells

    Publication

    - Year 2024

    Multicellular tumor spheroids are a good tool for testing new anticancer drugs, including those that may target cancer stem cells (CSCs), responsible for cancer progression, metastasis, and recurrence. Therefore, following the initial evaluation of the impact of antitumor unsymmetrical bisacridines (UAs) on lung and colon cancer cells using traditional monolayer cultures, I extended my investigations and applied the spherical model....

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  • Wybrane aspekty stanu struktury powierzchni stali hartowanej na przebieg nagniatania tocznego

    W artykule przedstawiono rezultaty badań oceny wpływu uzyskanej struktury powierzchni po toczeniu zahartowanej stali na efekty uzyskane po nagniataniu tocznym. Analizowano wybrane struktury różniące się kształtem profili i wartościami parametrów chropowatości. Porównano i oceniono uzyskane rezultaty po nagniataniu analizując wartości parametrów chropowatości i parametrów krzywej udziału materiałowego.

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  • Prognozowanie ostrzegawcze w małej firmie

    Publication

    W artykule pokazano możliwości zastosowania prostych metod prognostycznych do ostrzegania w małej firmie przed niekorzystnymi zjawiskami. Przedmiotem badań jest sprzedaż, a ze względu na występowanie w szeregu czasowym sezonowości, w celu wyznaczenia sygnałów ostrzegawczych dokonano porównań trendów prognozowanych i rzeczywistych w okresach jednoimiennych za pomocą pierwszych różnic. Do prognozowania sprzedaży wykorzystano proste...

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  • Początki i rozwój Katedry Automatyki na Wydziale Elektrycznym Politechniki Gdańskiej

    Niniejszy artykuł obejmuje historię powstawania i rozwoju Katedry Automatyki na Wydziale Elektrotechniki i Automatyki Politechniki Gdańskiej oraz związanego z tym powstawania i rozwoju na Wydziale kierunku studiów automatyka i robotyka. W kształceniu studentów tego kierunku studiów uczestniczyły także i inne katedry Wydziału. Zajęcia dydaktyczne z zastosowań automatyki prowadzili również pracownicy: Katedry Miernictwa Elektrycznego,...

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  • Branża IT – wyzwania związane z zarządzaniem kapitałem ludzkim

    Artykuł dotyczy procesów zarządzania kapitałem ludzkim w firmach IT, w których największe wyzwania wiążą się z dwoma obszarami: zatrudniania i zatrzymywania specjalistów IT w organizacji. Działy HR prześcigają się w stosowaniu coraz to nowszych rozwiązań, aby pozyskać oraz motywować kompetentnych informatyków do pracy na rzecz firmy. Głównym celem artykułu jest prezentacja działań dotyczących rekrutacji oraz motywowania pracowników...

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  • Face Recognition: Shape versus Texture

    Publication

    - Year 2015

    This paper describes experiments related to the application of well-known techniques of the texture feature extraction (Local Binary Patterns and Gabor filtering) to the problem of automatic face verification. Results of the tests show that simple image normalization strategy based on the eye center detection and a regular grid of fiducial points outperforms the more complicated approach, employing active models that are able to...

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  • Ab-initio study of electrical and optical properties of allylamine

    Publication

    - Year 2018

    The Density functional theory is one of most promising methodology in fast and accurate calculations of electrical and optical properties from the atomic basis. In this paper, we calculate electrical and optical properties of allylamine (2-propen 1- amine) in terms of accuracy and speed of calculations obtained by selection of DFT-1/2 method with ultrasoft Vanderbilt pseudopotentials. Comparison of density of states between...

  • Biopolymers in designing modern antimicrobial medical materials. Part I. Biopolymer medical materials - collagen, chitosan

    Publication

    The article is a review of the literature concerning the possible use of biopolymers for the preparation of dressings with antimicrobial activity. Authors show the potential of biopolymers: collagen and chitosan - which have the ability to immobilize and control the release of various active compounds - for providing the appropriate antibacterial, bacteriostatic and wound healing properties. Types of threats, for which the dressing...

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  • Synthesis of 2-amino-2,6-dideoxy-D-glucitol-6-sulfonic acid as a potential antifungal agent.

    Publication

    - Year 2013

    Glucosamine-6P (GlcN-6P) synthase catalyzes the first committed step in the biosynthetic pathway leading to the formation of UDP-GlcNAc, a sugar nucleotide precursor providing D-glucosamine for the formation of chitin and manoproteins. 2-Amino-2,6-dideoxy-D-glucitol-6-sulfonic acid is an analog of 2-amino-2-deoxy-D-glucitol 6-phosphate (GlcN-ol-6-P), a known inhibitor of GlcN-6-P synthase, in which the phosphate group of the latter...

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  • A modified method of vibration surveillance by using the optimal control at energy performance index

    A method of vibration surveillance by using the optimal control at energy performance index has been creatively modified. The suggested original modification depends on consideration of direct relationship between the measured acceleration signal and the optimal control command. The paper presents the results of experiments and Hardware- in-the-loop simulations of a new active vibration reduction algorithm based on the energy...

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