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Wyniki wyszukiwania dla: j-domain proteins
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An analysis of domain-based ship collision risk parameters
PublikacjaAccording to a lot of contemporary research on ship collision avoidance the classic approach parameters – distance at closest point of approach (DCPA) and time to the closest point of approach (TCPA) – are not sufficient for estimating ship collision risk and for planning evasive manoeuvres. Consequently new measures are introduced, often utilizing the concept of a ship domain. Their drawback, up to this point, was the lack of...
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Grabe J.:Recommendations of the "Committee for Waterfront Structures Harbours and Waterways" EAU 2012
PublikacjaRecenzja - Grabe J.: Recommendations of the "Committee for Waterfront Structures Harbours and Waterways" EAU 2012. Ernst & Sohn, Berlin 2015
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Marek J. Siemek and His Interpretation of the Idea of Transcendentalism
PublikacjaThe paper discusses in a concise manner and critical intent Marek J. Siemek’s conception of transcendental philosophy. Firstly, theory of knowledge does not belong to the epistemic level of reflection (Siemek’s stance) but it is precisely the other way around; namely, it is due to transcendental philosophy (critique of cognitive faculties) that it was possible to distinguish metaphysical, ontological and epistemological questions....
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Post mortem development of meat quality as related to changes in cytoskeletal proteins of chicken muscles
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Laplace domain BEM for anisotropic transient elastodynamics
PublikacjaIn this paper, we describe Laplace domain boundary element method (BEM) for transient dynamic problems of three-dimensional finite homogeneous anisotropic linearly elastic solids. The employed boundary integral equations for displacements are regularized using the static traction fundamental solution. Modified integral expressions for the dynamic parts of anisotropic fundamental solutions and their first derivatives are obtained....
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Conserved motifs of MutL proteins
PublikacjatThe MutL protein is best known for its function in DNA mismatch repair (MMR). However, there isevidence to suggest that MutL is not only the linker connecting the functions of MutS and MutH in MMR,but that it also participates in other repair systems, such as Very Short Patch (VSP), Base Excision (BER)and Nucleotide Excision Repair (NER). This study set out to identify the most highly conserved aminoacid sequence motifs in MutL...
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Immunogenic and protective activity of recombinant chimeric Toxoplasma gondii proteins
PublikacjaToxoplasmosis, one of the most common parasitic invasions worldwide, may pose a great threat for individuals with weakened immune system. The parasite also causes considerable economic losses due to infection of livestock. To date there is no efficient immunoprophylaxis for humans and animals, which would provide long-lasting protection against T. gondii invasion. Chimeric proteins, containing several selected fragments of parasite...
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A Framework of a Ship Domain-based Collision Alert System
PublikacjaThe paper presents a framework of a planned ship collision alert system. The envisaged system is compliant with IMO Resolution MSC.252 (83) “Adoption of the revised performance standards for Integrated Navigation Systems (INS)”. It is based on a ship domain-oriented approach to collision risk and introduces a policy of alerts on dangerous situations. The alerts will include cautions, warnings and alarms, which will be triggered...
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Modeling the Structure, Dynamics, and Transformations of Proteins with the UNRES Force Field
PublikacjaThe physics-based united-residue (UNRES) model of proteins ( www.unres.pl ) has been designed to carry out large-scale simulations of protein folding. The force field has been derived and parameterized based on the principles of statistical-mechanics, which makes it independent of structural databases and applicable to treat nonstandard situations such as, proteins that contain D-amino-acid residues. Powered by Langevin dynamics...
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Dissociative electron attachment to benzoic acid (C7H6O2)
PublikacjaThe dissociative electron attachment (DEA) to benzoic acid (C6H5COOH) has been studied using an experimental crossed beam setup of a quadrupole mass spectrometer and a trochoidal electron monochromator. Relative partial cross sections for the DEA to produce negative ion fragments show the main channels for dissociation. The comparison of the present results with the ultraviolet photoelectron spectrum of benzoic acid [J. Meeks,...
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RecA Proteins from Deinococcus geothermalis and Deinococcus murrayi - Cloning, Purification and Biochemical Characterisation
PublikacjaEscherichia coli RecA plays a crucial role in recombinational processes, the induction of SOS response and mutagenic lesion bypasses. It has also been demonstrated that RecA protein is indispensable when it comes to the reassembly of shattered chromosomes in gamma-irradiated Deinococcus radiodurans, one of the most radiation-resistant organisms known. Moreover, some functional differences between E. coli and D. radiodurans RecA...
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Domain Reduction in Hybrid Technique for Electromagnetic Wave Scattering Problems
PublikacjaThis paper proposes a combination of the field matching technique, finite element method and generalized impedance matrix, the main idea of which is to reduce the computational domain by surrounding a scatterer with the smallest convex shape and applying the field matching technique. This approach can be applied for arbitrary shaped scatterers and types of materials and allows for the reduction of the computational domain. In order...
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OSC - domain oriented ontology creation system
PublikacjaOntologies are, as part of semantic web, a basic component to enrich content available in the Internet with a meaning understandable for computers. In this publication an architecture and functionality of a domain oriented web portal for collaborative creation and storage of ontologies is presented. The system is being created by Gdańsk University of Technology Electronics, Telecommunications and Informatics faculty's Department...
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The J-curve phenomenon revisited
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Chirp-rate estimation of FM signals in the time-frequency domain
PublikacjaNovel dynamic representations of a complex signal in the time-frequency domain including: a channelized instantaneous complex frequency (CICF), a complex local group delay (CLGD) and a channelized instantaneous chirp-rate (CICR) are introduced. The proposed approach is based on the use of the gradient of the short-time Fourier transform complex phase. An interpretation of the newly-introduced distributions especially of the CICR...
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Density functional theory calculations on entire proteins for free energies of binding: Application to a model polar binding site
PublikacjaIn drug optimization calculations, the molecular mechanics Poisson-Boltzmann surface area (MM-PBSA) method can be used to compute free energies of binding of ligands to proteins. The method involves the evaluation of the energy of configurations in an implicit solvent model. One source of errors is the force field used, which can potentially lead to large errors due to the restrictions in accuracy imposed by its empirical nature....
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Fragmentomic analysis of biopeptides in silico released from milk proteins
PublikacjaThe fragmentomic-assisted method was employed to predict the biological potential of peptides derived from milk proteins hydrolyzed by papain and bromelain. Firstly, protein sequences were acquired from the BIOPEP-UWM database and then hydrolyzed by the above enzymes using a BIOPEP-UWM tool called “Enzyme(s) action”. The released peptides were defined as parent peptides and further analyzed for the presence of shorter peptidic...
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Study of Metrological Properties of Voltammetric Electrodes in the Time Domain
PublikacjaMetrological properties of voltammetric electrodes, in the situation where on their surface an electrochemical reaction of oxidizing/reduction takes place, were analyzed in this chapter. The properties of electrodes on which a reaction controlled by ion transport process takes place were taken into consideration. Also, it was analyzed how the electrode’s shape and the voltage polarizing the electrode influence this electrode’s...
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Molecular Recognition in Complexes of TRF Proteins with Telomeric DNA
PublikacjaTelomeres are specialized nucleoprotein assemblies that protect the ends of linear chromosomes. In humans and many other species, telomeres consist of tandem TTAGGG repeats bound by a protein complex known as shelterin that remodels telomeric DNA into a protective loop structure and regulates telomere homeostasis. Shelterin recognizes telomeric repeats through its two major components known as Telomere Repeat-Binding Factors, TRF1...
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J-lossless and extended J-lossless factorisations approach for delta do main Hinf control.
Publikacja.
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Dr hab. inż. Roman J. Wasielewski prof. nadzw. PG (1951-2012) - Wspomnienie
PublikacjaPrzedstawiono sylwetkę naukową zmarłego prof. nadzw. PG dr hab. inż. Romana J. Wasielewskiego, długoletniego pracownika Wydziału Mechanicznego PG. Profesor Roman Wasielewski był kontynuatorem długoletnich tradycji naukowych z zakresu mechanicznej technologii drewna.
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Common functionally important motions of the nucleotide‐binding domain of H sp70
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Dynamics of Chains as a Tool to Study Thermomechanical Properties of Proteins.
PublikacjaPolymer dynamics can be formulated on different levels of detail. One approach eliminates microscopic degrees of freedom and a polymer molecule is represented by a simplified structure—a chain. In the simplest case monomers of ideal chain have fixed length, and their orientation is independent of the orientations and positions of neighbouring monomers. This is reason that two monomers can co-exist at the same place. Ideal chain...
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JMATRIX - a package for relativistic J-matrix calculations in elastic scattering of electrons from model potentials
PublikacjaWe present a software package JMATRIX, consisting of two computer codes written in FORTRAN 95 and parallelized with OpenMP, implementing the so-called J-matrix method, applied to elastic scattering of electrons on the radial potential, vanishing faster than Coulomb one. In the J-matrix method, physical scattering problem is replaced by using well-defined model, which is solved analytically. Presented software implements both non-relativistic...
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Determination of denaturation temperature of connective tissue proteins by viscometric measurements.
Dane BadawczeViscometric denaturation temperature of connective tissue proteins was determined by measuring viscosity with a Brookfield viscometer, using a LV SC4 - 18, 25 or LV3 spindle and shear rates from 50 to 110 s-1 (Fig.1). Freeze-dried protein samples were dissolved in 0.5 M acetic acid at 4 °C and concentration of 20 mg/mL. The solution was stirred with...
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Borrelia burgdorferi BmpA-BBK32 and BmpA-BBA64: New Recombinant Chimeric Proteins with Potential Diagnostic Value
PublikacjaCurrently, the diagnosis of Lyme disease is based mostly on two-tiered serologic testing. In the new generation of immunoenzymatic assays, antigens comprise whole-cell lysates of members of the Borrelia burgdorferi sensu lato (s.l.) species complex, with the addition of selected recombinant proteins. Due to the high diversity of members of the B. burgdorferi s.l. genospecies and the low degree of conservation among the amino acid...
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The Impact of the Antigenic Composition of Chimeric Proteins on Their Immunoprotective Activity against Chronic Toxoplasmosis in Mice
PublikacjaToxoplasmosis may pose a serious threat for individuals with weakened or undeveloped immune systems. However, to date, there is no specific immunoprophylaxis for humans. Thus, the aim of this study was to evaluate the immunogenicity of three trivalent—SAG2-GRA1-ROP1L (SGR), SAG1L-MIC1-MAG1 (SMM), and GRA1-GRA2-GRA6 (GGG)—and two tetravalent—SAG2-GRA1-ROP1-GRA2 (SGRG) and SAG1-MIC1-MAG1-GRA2 (SMMG)—chimeric T. gondii proteins, as...
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Geier R., Angelmaier V., Gaubner C.-A., Kohoutek J.: Integrale Brücken. Entwurf, Berechnung, Ausführung, Monitoring
PublikacjaGeier R., Angelmaier V., Gaubner C.-A., Kohoutek J.: Integrale Brücken. Entwurf, Berechnung, Ausführung, Monitoring. Ernst & Sohn, Berlin 2017.
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Improvement of Fingerprinting Method based on Hill Cipher by using Frequency Domain
PublikacjaThe main goal of this paper is to present the advantages of a digital fingerprinting in a frequency domain over a pixel domain, in case of VoD services (Video on Demand). The paper presents basic issues of a multimedia data protection by digital fingerprinting. It also describes threats to embedded fingerprints from both collusion attacks and from a transmission itself. Possible solution was presented on the example of the DCT...
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Cadmium tri-tert-butoxysilanethiolates. Structural and spectroscopic models of metal sites in proteins.
PublikacjaW publikacji opisano syntezy i struktury dla dwóch heteroleptycznych kompleksów kadmu z rdzeniem CdS2NO2 i CdS2N2. Bis(tri-tert-butoksysilanotiolato)(1-metyloimidazol)kadmu(II) oraz bis(tri-tert-butoksysilanotiolato)bis(1-metyloimidazol)kadmu(II) współistnieją w roztworze chloroformu przy różnych stężeniach Bis(tri-tert-butoksysilanotiolanu) kadmu(II) i 1 metyloimidazolu. Rotzwór ten został scharakteryzowany za pomocą analizy spektralnej...
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Dimensionality-Reduced Antenna Modeling with Stochastically Established Constrained Domain
PublikacjaOver the recent years, surrogate modeling methods have become increasingly widespread in the design of contemporary antenna systems. On the one hand, it is associated with a growing awareness of numerical optimization, instrumental in achieving high-performance structures. On the other hand, considerable computational expenses incurred by massive full-wave electromagnetic (EM) analyses, routinely employed as a major design tool,...
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Data Domain Adaptation in Federated Learning in the Breast Mammography Image Classification Problem
PublikacjaWe are increasingly striving to introduce modern artificial intelligence techniques in medicine and elevate medical care, catering to both patients and specialists. An essential aspect that warrants concurrent development is the protection of personal data, especially with technology's advancement, along with addressing data disparities to ensure model efficacy. This study assesses various domain adaptation techniques and federated...
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Two-Stage Variable-Fidelity Modeling of Antennas with Domain Confinement
PublikacjaSurrogate modeling has become the method of choice in solving an increasing number of antenna design tasks, especially those involving expensive full-wave electromagnetic (EM) simulations. Notwithstanding, the curse of dimensionality considerably affects conventional metamodeling methods, and their capability to efficiently handle nonlinear antenna characteristics over broad ranges of the system parameters is limited. Performance-driven...
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TIME- AND FREQUENCY-DOMAIN QUASI-2D SMALL-SIGNAL MOSFET MODELS
PublikacjaA novel approach to small-signal MOSFET modeling is presented in this book. As a result, time- and frequency-domain physics-based quasi-2D NQS four-terminal small-signal MOSFET models are proposed. The time-domain model provides the background to a novel DIBL-included quasi‑2D NQS four-terminal frequency-domain small-signal MOSFET model. Parameters and electrical quantities of the frequency-domain model are described by explicit...
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Multi-domain and Context-Aware Recommendations Using Contextual Ontological User Profile
PublikacjaRecommender Systems (RS) became popular tools in many Web services like Netflix, Amazon, or YouTube, because they help a~user to avoid an information overload problem. One of the types of RS are Context-Aware RS (CARS) which exploit contextual information to provide more adequate recommendations. Cross-Domain RS (CDRS) were created as a response to the data sparsity problem which occurs when only few users can provide reviews or...
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Zaliczenie SP RiF-59 dr J. Kujawska
Kursy OnlineZaliczenie SP RiF-59 dr J. Kujawska
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Low-Cost Behavioral Modeling of Antennas by Dimensionality Reduction and Domain Confinement
PublikacjaBehavioral modeling has been rising in importance in modern antenna design. It is primarily employed to diminish the computational cost of procedures involving massive full-wave electromagnetic (EM) simulations. Cheaper alternative offer surrogate models, yet, setting up data-driven surrogates is impeded by, among others, the curse of dimensionality. This article introduces a novel approach to reduced-cost surrogate modeling of...
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Time-domain description of point-source acoustic wavefields as a useful approach in ultrasonic techniques
PublikacjaIn traditional acoustics, field problems are usually treated in the frequency domain, broadband fields being reduced to superposition of harmonic spectrum components. However, this approach is inherently acausal and it is known that in case of arbitrary signals, the distribution-based, time-domain description can be more effective. The present paper is an attempt to expand the time-domain linear systems formalism onto space problems...
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Time-Domain Description of Point-Source Acoustic Wavefields as a Useful Approach in Ultrasonic Techniques
PublikacjaIn traditional acoustics, field problems are usually treated in the frequency domain, broadband fields being reduced to superposition of harmonic spectrum components. However, this approach is inherently acausal and it is known that in case of arbitrary signals, the distribution-based, time-domain description can be more effective. The present paper is an attempt to expand the time-domain linear systems formalism onto space problems...
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Ship domain applied to determining distances for collision avoidance manoeuvres in give-way situations
PublikacjaShip domain is often used in marine navigation and marine traffic engineering as a safety condition. The basic idea behind those applications is that an encounter of two or more ships can be considered safe if neither of ship domains is intruded by other ships. Research utilising this approach has been documented in numerous works, including publications on optimising collision avoidance manoeuvres performed to fulfil domain-based...
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A ship domain-based model of collision risk for near-miss detection and Collision Alert Systems
PublikacjaThe paper presents a new model of ship collision risk, which utilises a ship domain concept and the related domain-based collision risk parameters. An encounter is here described by five variables representing: degree of domain violation (DDV), relative speed of the two vessels, combination of the vessels’ courses, arena violations and encounter complexity. As for the first three variables, their values can be directly computed...
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Comparison of backscattered sea bottom echo modelling in the acoustic pressure domain and in the intensity domain
PublikacjaPrzedstawiono dwie metody modelowania rozpraszania wstecznego na dnie morskim: modelowania ciśnienia akustycznego opartego na aproksymacji Kirchhoffa oraz modelowania natężenia echa przy założeniu dominacji rozpraszania niekoherentnego. Porównano i przedyskutowano wyniki w odniesieniu do problemu poszukiwania jak najwłaściwszego opisu zjawiska rozpraszania sygnału akustycznego na dnie.
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Distributed Inter-Domain Link Capacity Optimization for Inter-Domain IP/MPLS Routing
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Multi-objective antenna design by means of sequential domain patching
PublikacjaA simple yet robust methodology for rapid multiobjective design optimization of antenna structures has been presented. The key component of our approach is sequential domain patching of the design space which is a stencil-based search that aims at creating a path that connects the extreme Pareto-optimal designs, obtained by means of single-objective optimization runs. The patching process yields the initial approximation of the...
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Time domain model of the resonance-based electromagnetic pulses emission system
PublikacjaIn the literature, the emission properties of the electromagnetic field pulse systems based on high voltage antennas (HVR) have been widely described. In order to increase the emission efficiency by extending duration and increasing amplitude of the impulse it is possible to use a resonance system tuned to the parameters of the signal shaped in the pulse forming circuit. The synthesis of a time-domain simulation model of a complex...
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Analysis of the Factors Affecting Static In Vitro Pepsinolysis of Food Proteins
PublikacjaIn this meta-analysis, we collected 58 publications spanning the last seven decades that reported static in vitro protein gastric digestion results. A number of descriptors of the pepsinolysis process were extracted, including protein type; pepsin activity and concentration; protein concentration; pH; additives; protein form (e.g., ‘native’, ‘emulsion’, ‘gel’, etc.); molecular weight of the protein; treatment; temperature; and...
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Swapping Space for Time: An Alternative to Time-Domain Interferometry
PublikacjaYoung's double-slit experiment [1] requires two waves produced simultaneously at two different points in space. In quantum mechanics the waves correspond to a single quantum object, even as complex as a big molecule. An interference is present as long as one cannot tell for sure which slit is chosen by the object. The more we know about the path, the worse the interference. In the paper we show that quantum mechanics allows for...
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Application of Ontology In the ITIL Domain
PublikacjaBusiness standards tend to be less formal in description then strict technical norms. Authors of this chapter suggest applying ontological description (powered by the capabilities of the OWL language) to express Information Technology Infrastructure Library (ITIL). One of the goals of this initial study is to determine the usefulness of such semantic model in organizations that adopted or plan to adopt ITIL.
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Concentration of proteins in the whey stream
PublikacjaZastosowano metodę separacji pianowej do odzyskiwania białka z serwatki. Wykazano silny wpływ prędkości powietrza w kolumnie, początkowego stężenia białka w serwatce i pH roztworu na przebieg i skuteczność flotacji. Współczynnik wzbogacenia maleje ze wzrostem prędkości przepływu powietrza oraz ze wzrostem początkowego stężenia białka serwatkowego. Najwyższą wartość współczynnika wzbogacenia uzyskano dla pH naturalnej serwatki.
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Optimization of parallel implementation of UNRES package for coarse‐grained simulations to treat large proteins
PublikacjaWe report major algorithmic improvements of the UNRES package for physics-based coarse-grained simulations of proteins. These include (i) introduction of interaction lists to optimize computations, (ii) transforming the inertia matrix to a pentadiagonal form to reduce computing and memory requirements, (iii) removing explicit angles and dihedral angles from energy expressions and recoding the most time-consuming energy/force terms...