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Wyniki wyszukiwania dla: hic
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Examination of cyp51A and cyp51B expression level of the first Polish azole resistant clinical Aspergillus fumigatus isolate
PublikacjaAspergillus fumigatus is one of the most prevalent airborne fungal pathogens causing infections worldwide. Most A. fumigatus strains are susceptible to azoles, which are administered as the first line therapeutics. However, during last decade the acquired resistance to triazoles by these species has been described. There is a number of publications concerning the examination of clinical A. fumigatus strains from different countries,...
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Removal of Arsenic from Wastewater Using Hydrochar Prepared from Red Macroalgae: Investigating Its Adsorption Efficiency and Mechanism
PublikacjaArsenic (As) is a prominent carcinogen component produced via both geogenic and anthropogenic processes, posing serious risks to human health. This study aimed to investigate the potential of hydrochar prepared from red macroalgae for removing As from synthetic wastewater. The hydrochar was produced through 5 h hydrothermal carbonization (HTC) treatment at 200 °C, and then, chemically activated with ferric chloride hexahydrate...
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Economic crisis in Croatia
PublikacjaCroatia is becoming the 28th member of the European Union on July 1st, 2013. Croatia has gone a long way from a socialistic republic to an independent country recognized as one of the economic tigers of the Western Balkans in the first decade of the 21st century. Croatia has been hit by a global crisis which turned out to be a huge external shock for the region of the Western Balkans. Although it does not enter the economy through...
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Synthetic lipopeptides as potential topical therapeutics in wound and skin care: in vitro studies of permeation and skin cells behaviour
PublikacjaSeveral Gly-His-Lys analogues were obtained to investigate their antimicrobial properties. Three lipophilic analogues with the structure numbering 1b, 2b, 4b, exhibit significant effect against bacteria and were selected for in vitro evaluation of skin cells behaviour. In the present studies, an in vitro model of wound repair, proliferative cell staining, and tracking of living cells were used. Cell proliferation and cell migration,...
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Effect of Ethanol Extracts of Propolis (EEPs) against Staphylococcal Biofilm—Microscopic Studies
PublikacjaStaphylococci growing in the form of biofilm exhibit high resistance to a plethora of antibiotics. The aim of the study was to assess the influence of ethanolic extract of propolis (EEPs) on S. epidermidis ATCC 35984 biofilm using fluorescent microscopy. Propidium iodide (PI) and SYTO 9 were used for differentiation of live and dead cells, and calcofluor white was used to stain the extracellular matrix, the self-produced extracellular...
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Photosensitive and pH-dependent activity of pyrazine-functionalized carbazole derivative as promising antifungal and imaging agent
PublikacjaCarbazole skeleton plays a significant role as a structural scaffold of many pharmacologically active compounds. Pyrazine-functionalized carbazole derivative was constructed by coupling 2-amino-5-bromo-3-methylaminepyrazine (ABMAP) into 3 and 6 positions of the carbazole ring. Multi-experimental methods were used, e.g., potentiometric, spectroscopic (ATR, UV, XRD powder,1H and13C NMR), electrochemical (cyclic voltammetry), and...
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Mechanical-Level Hardware-In-The-Loop and Simulation in Validation Testing of Prototype Tower Crane Drives
PublikacjaIn this paper, the static and dynamic simulations, and mechanical-level Hardware-In-the-Loop (MHIL) laboratory testing methodology of prototype drive systems with energy-saving permanent-magnet electric motors, intended for use in modern construction cranes is proposed and described. This research was aimed at designing and constructing a new type of tower crane by Krupiński Cranes Company. The described research stage was necessary...
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Mechanical Performance and Environmental Assessment of Sustainable Concrete Reinforced with Recycled End-of-Life Tyre Fibres
PublikacjaThe presented research’s main objective was to develop the solution to the global problem of using steel waste obtained during rubber recovery during the tire recycling. A detailed comparative analysis of mechanical and physical features of the concrete composite with the addition of recycled steel fibres (RSF) in relation to the steel fibre concrete commonly used for industrial floors was conducted. A study was carried out using...
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All-gather Algorithms Resilient to Imbalanced Process Arrival Patterns
PublikacjaTwo novel algorithms for the all-gather operation resilient to imbalanced process arrival patterns (PATs) are presented. The first one, Background Disseminated Ring (BDR), is based on the regular parallel ring algorithm often supplied in MPI implementations and exploits an auxiliary background thread for early data exchange from faster processes to accelerate the performed all-gather operation. The other algorithm, Background Sorted...
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On the deformation and frequency analyses of SARS-CoV-2 at nanoscale
PublikacjaThe SARS-CoV-2 virus, which has emerged as a Covid-19 pandemic, has had the most significant impact on people's health, economy, and lifestyle around the world today. In the present study, the SARS-CoV-2 virus is mechanically simulated to obtain its deformation and natural frequencies. The virus under analysis is modeled on a viscoelastic spherical structure. The theory of shell structures in mechanics is used to derive the governing...
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Seeding enhancement for microcrystaline diamond layers growth on non-diamond substrates
PublikacjaThe present paper gives an overview on the possible methods of seeding substrates for diamond layers growth. Diamond in reason of his properties is very desirable material in microelectronic, biomedical and waste treatment sensors. Microcrystalline diamond for these applications must be grown on silicon substrate in microwave plasma assisted chemical vapor deposition (MPACVD). To grow diamond on non-diamond surface pre-growth...
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Modern approach for determination of lactulose, mannitol and sucrose in human urine using HPLC-MS/MS for the studies of intestinal and upper digestive tract permeability
PublikacjaA new analytical procedure was described for the simultaneous determination of lactulose, mannitol and sucrose in urine, in which HILIC chromatography and tandem mass spectrometry detection are used. Sugars are orally administered for the estimation of intestinal permeability in children digestive tract. Samples were purified by dispersive solid phase extraction (d-SPE) using Amberlite MB150 resin. Raffinose was selected as an...
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Anticancer and antimicrobial properties of novel η6-p-cymene ruthenium(ii) complexes containing a N,S-type ligand, their structural and theoretical characterization
PublikacjaRuthenium(II) complexes are lately of great scientific interest due to their chemotherapeutic potential asanticancer and antimicrobial agents. Here we present the synthesis of new pyrazole carbothioamidederivatives and their four arene–ruthenium complexes. The title compounds were characterized with theapplication of IR, NMR, mass spectrometry, elemental analysis and X-ray diffraction. Additionally, for newcomplexes DFT calculations...
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Design of Structure of Tension Leg Platform for 6 MW Offshore Wind Turbine Based On Fem Analysis
PublikacjaThe article presents the calculation and design stages of the TLP platform serving as a supporting construction of a 6 MW offshore wind turbine. This platform is designed to anchor at sea at a depth of 60 m. The authors presented the method of parameterization and optimization of the hull geometry. For the two selected geometry variants, the load and motion calculations of the platform subjected to wind, wave and current under...
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Where the Second World War in Europe broke out: the land-scape history of Westerplatte, Gdańsk/Danzig
PublikacjaWesterplatte is known as the place where the Second World War in Europe broke out. However, its history covers many other events involving Polish, German, Russian and even French politics over the last three centuries - neglected by many papers published in the current discussion. Due to its location at the entrance to the main harbour on the Baltic Sea entrance, Wester-platte-Peninsula is cartographically the best-documented part...
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Politics and urban artifacts in cities: what are they and how are they interconected?
PublikacjaThis research, analyses the effect of politics on a city and its image, via their control over the formation or changes on urban artifacts. It analyses the concepts introduced in Aldo Rossi’s architectural monograph, The Architecture of the City, in the chapter titled ‘Politics as Choice’, and his idea that a city’s image is a reflection of its political institutions and the choices people in authority make. Monuments and architecture...
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Overcoming Challenges of Virtual Scrum Teams: Lessons Learned Through an Action Research Study
PublikacjaAfter the COVID-19 breakout, agile teams found themselves in situations that “pure agilists” and textbooks on agile methods had preferred to ignore. Whereas agile mindsets helped them to quickly shift to remote work, mere virtualization of agile practices often proved insufficient, and several challenges emerged. This paper reports on an Action Research project carried out in Lufthansa Systems Poland with the aim of (1) revisiting...
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Biblioteka w nowym świecie czy nowy świat w bibliotece
PublikacjaWraz z głębokimi zmianami zachodzącymi we współczsnym świecie, zmieniają się także instytucje kultury, w tym również biblioteki. Na podstawie badań ilościowych i jakościowych autorki zaproponowały innowacyjny sposób szacowania całkowitej wartości i produktywności wspólczesnych bibliotek.
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Double-Headed Cationic Lipopeptides: An Emerging Class of Antimicrobials
Publikacja -
Problemy ukrytych aportów w spółkach publicznych
PublikacjaTransakcje z samym sobą należą do typowych zachowań dominującego akcjonariusza nadużywającego swojej pozycji w spółce publicznej. W artykule omówiono ukryte aporty, które są efektem tego typu zachowań. Wskazano, czym różnią się ukryte aporty od prawidłowo wnoszonych aportów i jakie są negatywne konsekwencje tych pierwszych. W rozważaniach uwzględniono aspekty prawne tego zjawiska. Opisane zostały przypadki obchodzenia przepisów...
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Impact of Urbanization on Stormwater Runoff from a Small Urban Catchment: Gdańsk Małomiejska Basin Case Study
PublikacjaThis paper deals with the impact of different forms of urbanization on the basin outflow. The influence of changes in land cover/use, drainage system development, reservoirs, and alternative ways of stormwater management (green roofs, permeable pavements) on basin runoff was presented in the case of a small urban basin in Gdańsk (Poland. Seven variants of area development (in the period of 2000-2012) – three historical and four...
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Targeting yeast topoisomerase II by imidazo and triazoloacridinone derivatives resulting in their antifungal activity
PublikacjaFungal pathogens are considered as serious factors for deadly diseases and are a case of medical concern. Invasive fungal infections also complicate the clinical course of COVID-19, leading to a significant increase in mortality. Furthermore, fungal strains' multidrug resistance has increased the demand for antifungals with a different mechanism of action. The present study aimed to identify antifungal compounds targeting yeast...
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Sleep alterations in treatment-resistant depression patients undergoing ketamine treatment
PublikacjaBackground This study examines self-reported sleep alterations in treatment-resistant depression (TRD) inpatients following intravenous ketamine administration. Methods This is a post-hoc analysis of a naturalistic observational study, which enrolled 28 inpatients with treatment-resistant major depressive disorder and analyzed self-reported sleep changes (items 1–4; ‘insomnia’, ‘nighttime restlessness’, ‘early morning waking’,...
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Ergonomic Aspects of Transport of Patient through the Operating Theatre
PublikacjaOne of the most crucial decisions to be made while designing and re-modernizing an operating theatre is selecting a method of transporting the patient through the hospital’s spatial arrangement. This decision, while irrelevant at first thought, implies numerous project and functional consequences. Designing an operating theatre within a hospital is related to numerous specialist requirements with an aim of minimizing the risk of...
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FTIR, Raman spectroscopy and HT-XRD in compatibility study between naproxen and excipients
PublikacjaDetection of incompatibility between an active pharmaceutical ingredient (API) and excipients, including the selection of the most biopharmaceutical advantageous excipients is extremely important in the pre-formulation process of developing a solid dosage form technology. Therefore, having fast and reliable methods for identifying incompatibility is fundamental in pharmaceutical technology. For this purpose, combined Fourier transform...
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Wybrane problemy nagniatania tocznego stali twardych ceramiką na tokarce cnc
PublikacjaNagniatanie jest obróbką wykończeniową, bezubytkową, polegającą na plastycznym odkształcaniu warstwy wierzchniej przedmiotu. Proces nagniatania jest zazwyczaj stosowany do stali miękkich, aczkolwiek metodę tę wykorzystuje się również do obróbki materiałów twardych, takich jak: hartowana stal, której twardoć przewyższa wartoć 40 HRC. Do nagniatania tocznego stali twardych stosowane są narzędzi z łożyskowaniem hydrostatycznym i...
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Mining Knowledge of Respiratory Rate Quantification and Abnormal Pattern Prediction
PublikacjaThe described application of granular computing is motivated because cardiovascular disease (CVD) remains a major killer globally. There is increasing evidence that abnormal respiratory patterns might contribute to the development and progression of CVD. Consequently, a method that would support a physician in respiratory pattern evaluation should be developed. Group decision-making, tri-way reasoning, and rough set–based analysis...
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Determinants of the primary stability of cementless acetabular cup implants: A 3D finite element study
PublikacjaPrimary stability of cementless implants is crucial for the surgical success and long–term stability. However, primary stability is difficult to quantify in vivo and the biomechanical phenomena occurring during the press–fit insertion of an acetabular cup (AC) implant are still poorly understood. The aim of this study is to investigate the influence of the cortical and trabecular bone Young's moduli Ec and Et, the interference...
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PRINCIPLES OF ARTIFICIAL INTELLIGENCE APPLICATION IN CONTROL OF THE ENTERPRISE
PublikacjaThe implementation of the tasks of evaluating historical financial information, the control or audit of business activities are based primarily on professional judgments about the object of study of a professional accountant or auditor. Their findings are drawn on the basis of the study of documents, the use of audit evidence, risk assessment, etc. There is always a probability (and rather high) that professional judgment will...
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Composite Polyurethane-Polylactide (PUR/PLA) Flexible Filaments for 3D Fused Filament Fabrication (FFF) of Antibacterial Wound Dressings for Skin Regeneration
Publikacjahis paper addresses the potential application of flexible thermoplastic polyurethane (TPU) and poly(lactic acid) (PLA) compositions as a material for the production of antibacterial wound dressings using the Fused Filament Fabrication (FFF) 3D printing method. On the market, there are medical-grade polyurethane filaments available, but few of them have properties required for the fabrication of wound dressings, such as flexibility...
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The Anti-Staphylococcal Potential of Ethanolic Polish Propolis Extracts
PublikacjaAbstract: The principal objective of this study was to determine the anti-staphylococcal potential of ethanol extracts of propolis (EEPs). A total of 20 samples of propolis collected from apiaries located in different regions of Poland were used in the study. The two-fold broth microdilution method revealed some important differences in the antimicrobial activity of investigated EEPs. Up to the concentration of 4096 µg/mL no activity...
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Cross-sections for electron-scattering from 2-methyl-1-buten-3-yne, C 5 H 6 , molecules
PublikacjatCross-sections for electron collisions with the 2-methyl-1-buten-3-yne [H2C C(CH3)C CH] moleculewere measured and calculated. Absolute grand-total electron-scattering cross-section (TCS) was takenat impact energies from 0.6 to 300 eV in the linear electron-transmission experiment. The TCS energydependence for the electron–C5H6collision has two prominent enhancements separated with a deepminimum located near 1.8 eV. In addition,...
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Przed modernizmem - style w gdyńskiej architekturze lat dwudziestych
PublikacjaZarówno w historiografii architektury polskiej jak i europejskiej lata dwudzieste XX wieku omawiane są głównie w kontekście rodzącego się modernizmu. Nic w tym zresztą nie ma dziwnego, bo to właśnie ten nurt wyznaczał nowe trendy i w przyszłości decydować miał o dziejach architektury w całym stuleciu. Odchodziła w przeszłość trwająca od połowy XIX wieku epoka historyzmu, a zaczynała się epoka nowa, modernistyczna. Tak więc oblicze...
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Power Hardware-In-the-Loop Approach for Autonomous Power Generation System Analysis
PublikacjaThe article presents the Power Hardware-In-the-Loop (PHIL) dynamic model of a synchronous generator of 125 kVA for autonomous power generation system analysis. This type of system is typically composed of electrical energy sources in the form of several diesel generator units with synchronous machines, the main distribution switchboard and different loads. In modern power distribution systems, the proposed power management strategies...
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Extended micropolar approach within the framework of 3M theories and variations thereof
PublikacjaAs part of his groundbreaking work on generalized continuum mechanics, Eringen proposed what he called 3M theories, namely the concept of micromorphic, microstretch, and micropolar materials modeling. The micromorphic approach provides the most general framework for a continuum with translational and (internal) rotational degrees of freedom (DOF), whilst the rotational DOFs of micromorphic and micropolar continua are subjected...
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Enhancing Economic Development Through ICT-Based Governance: Evidence for Developing Countries
Publikacjahis shows novel empirical evidence on how e-government solutions enhance the emergence of inclusive societies, increase institutional quality, and through that channels dynamize economic development in developing countries. With this aim we examine digital development inequalities adopting 2 core ICT indicators: mobile cellular telephony and Internet users; and gross per capita income and Human Development Index to show the level...
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Modeling the debonding process of osseointegrated implants due to coupled adhesion and friction
PublikacjaCementless implants have become widely used for total hip replacement surgery. The long-term stability of these implants is achieved by bone growing around and into the rough surface of the implant, a process called osseointegration. However, debonding of the bone–implant interface can still occur due to aseptic implant loosening and insufficient osseointegration, which may have dramatic consequences. The aim of this work is to...
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Wzory kreatywności. Koncepcja modelu prawdopodobieństwa działania kreatywnego jako narzędzie badania procesu twórczego w środowisku miejskim
PublikacjaWspółczesne koncepcje kształtowania miast, takie jak zrównoważony rozwój, miasto odporne, inteligentne miasto, miasto kreatywne, tworzą obecnie ramy urbanistyki o charakterze jednej uogólnionej idei kształtującej środowisko społeczno-materialne. Kontekstualne ujęcie badań kreatywności opisuje zależności między środowiskiem miejskim a twórczością w mieście kreatywnym. Ujęcie procesualne kreatywności stanowi hic et nunc urbanizmu,...
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Rozumieć Kanta całościowo czyli o Opus postumum Immanuela Kanta
PublikacjaTekst pokazuje fundamentalne znaczenie Opus postumum Kanta dla zrozumienia całości jego filozofii, dynamiki jej rozwoju, jej trudności i niekonsekwencji. Podstawowym problemem jest tu problem przejścia od metafizyki przyrody do fizyki. Omawiając pracę Tomasza Kupścia tekst pokazuje jak ważne w rozumieniu Kanta jest wyjście poza problematykę filozofii przyrody w stronę filozofii Boga, bo zwieńczenie filozofii transcendentalnej...
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Analizy ilości i jakości odpływu wód deszczowych i roztopowych z kontrolowanej zlewni zurbanizowanej
PublikacjaIstotnym problemem Gdańska staje się bezpieczeństwo ekologiczne związane ze spływami miejskimi odprowadzanymi bezpośrednio do wód powierzchniowych, często akwenów użyteczności publicznej. W latach 2011÷2013, Katedra Hydrotechniki Wydziału Inżynierii Lądowej i Środowiska Politechniki Gdańskiej, we współpracy z Wojewódzkim Funduszem Ochrony Środowiska i Gospodarki Wodnej w Gdańsku oraz Gdańskimi Melioracjami, podjęła się wdrożenia...
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Fabrication and characterization of composite TiO2 nanotubes/ boron-doped diamond electrodes towards enhanced supercapacitors
PublikacjaThe composite TiO2 nanotubes / boron-doped diamond electrodes were deposited using Microwave Plasma Enhanced Chemical Vapor Deposition resulting in the improved electrochemical performance. This composite electrode can deliver high specific capacitance of 7.46 mF cm‐− 2 comparing to boron-doped diamond (BDD) deposited onto flat Ti plate (0.11 mF cm‐− 2).The morphology and composition of composite electrode were characterized...
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Szkoła z autorytetem
PublikacjaNieczęsto spotyka się ludzi, którzy pracują z pasją i poświęcają się swojej pracy niemal całkowicie. Opowiem historię człowieka, który będąc na stanowisku dyrektora szkoły przez blisko 30 lat, stworzył ją niemal od podstaw, a owoc jego pracy jest więcej niż imponujący. Jako dyrektor pracował z wieloma ludźmi, zdobył wiele kontaktów zarówno tych zawodowych, jak i prywatnych. Był autorem wielu sukcesów, nie ominęły go również błędy...
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Scattering of electrons by a 1,2-butadiene (C4H6) molecule: measurements and calculations
PublikacjaWe present the results of experimental and theoretical study on electron collisions with a 1,2-butadiene (H2C=C=CHCH3) molecule. Absolute grand-total cross sections (TCSs) were measured using a linear electron-transmission method for collision energies in the 0.5–300 eV range. Two distinct features in the TCS energy curve were detected: a narrow peak located at 2.3 eV and a broad enhancement centered around 9 eV. We attributed...
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Validation of a virtual test environment for C2X communication under radio jamming conditions
PublikacjaIn this paper, we propose a novel car-2-x communication security testing methodology in the physical layer of wireless systems. The approach is dedicated to automated testing of autonomous vehicles and it is essential for such complex systems operation, especially with regard to safety and security issues. It is based on scenario-driven testing in virtual and real test environments created from collected or simulated data. The...
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BeesyCluster: Architektura systemu dostepu do sieci klastrów przez WWW/Web Services.
PublikacjaNiniejsza praca prezentuje system BeesyCluster, który integruje rozproszone klastry poprzez łatwy w użyciu interfejs WWW oraz Web Services. W wersji pilotowej system uruchomiony zostanie w charakterze portalu dostępowego do klastrów gdańskiej sieci TASK wykorzystując 128-procesorowy klaster galera oraz 256-procesorowy 64-bitowy klaster holk jak również laboratoria badawcze Wydziału ETI Politechniki Gdańskiej. System, oparty o technologię...
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Parallel Programming for Modern High Performance Computing Systems
PublikacjaIn view of the growing presence and popularity of multicore and manycore processors, accelerators, and coprocessors, as well as clusters using such computing devices, the development of efficient parallel applications has become a key challenge to be able to exploit the performance of such systems. This book covers the scope of parallel programming for modern high performance computing systems. It first discusses selected and...
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Expression of a GDSL esterase from Pseudomonas sp. S9 in Pichiapastoris
PublikacjaCold active lipolytic enzymes are promising to replace the conventional enzymes processes of biotechnological industries. One of the most important feature of the cold-active lipases and esterases is that they offer economic benefits through energy saving. In general, they exhibit high activity at low temperatures and low thermostability at moderate temperatures. Lipolytic enzyme EstS9 was isolated from Pseudomonas sp. S9. A multiple...
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Effect of the welding environment and storage time of electrodes on the diffusible hydrogen content in deposited metal
PublikacjaIn the study the glycerin displacement method was used for determination of diffusible hydrogen content in deposited metal. Specimens were welded in the air and in the water with covered rutile electrodes. The first part of the specimens was made immediately after opening the package of the electrodes. The electrodes were then stored in opened packages in laboratory conditions that allowed for contact with the air for three years....
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pH-dependent composite coatings for controlled drug delivery system - Review
PublikacjaNowadays in case of long-term implants, the most common postoperative complications are bacterial infections, which in consequence may provoke loos- ening of the implants in the primary phase of stabilization. Bacterial infections are currently the most frequent cause of revision surgery of the implants such as hip joint endoprosthesis, knee joint endoprosthesis and dental implants. In order to provide the local and long-term antibacterial...
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Thermal and economic investigation of straight and U-bend double tube heat exchanger with coiled wire turbulator
PublikacjaExperimental research has been carried out for four individual heat exchanger constructions, i.e., plain double tube, turbulized double tube, plain U-bend and U-bend with turbulator. Tests were made for the water-water system. The study covered a wide measuring range, i.e., Re = 800–9000 – on the shell side, for a constant cold water temperature of 9 ◦C and hot water of 50 ◦C. The heat exchangers were made from copper tubes with...