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Search results for: ANTI-CORRUPTION
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Hydrogen migration in formation of NH(A3Π) radicals in photodissociations of isoxazole and pyridine molecules
PublicationIn the present study, the H atom migration was observed in the photodissociation processes of the isoxazole and pyridine molecules in the gas-phase, applying the photon-induced fluorescence spectroscopy (PIFS).
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Formation of CN (B2∑+) radicals in the vacuum-ultraviolet photodissociation of pyridine and pyrimidine molecules
PublicationFormation of the excited CN(B2∑+) free radicals in the photodissociation of pyridine (C5H5N) and pyrimidine (C4H4N2) molecules was investigated over the energy ranges 16–27 and 14.7–25 eV, respectively. Photon-induced fluorescence spectroscopy was applied to detect the vibrationally and rotationally excited CN radicals by recording the B2∑+→X2∑+ emission bands (violet system). The measured dissociation yield curves demonstrate...
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Study of ultraviolet-visible fluorescence emission following resonant Auger decay of the 2p-1nl core-excited states of argon atoms
PublicationWe have studied the excitation and relaxation of Ar+ ions populated in resonant Auger decay from the Ar 2p−1nl core-excited states by using ultraviolet-visible fluorescence spectroscopy and photon-photon delayed coincidence technique. Fluorescence emission yields were measured in the photon energy range of 240-–255 eV for the 3s23p4(1D)5s(2D) → 3s23p4(1D)4p(2F) (393 nm) and 3s23p4(1D)4d(2F) → 3s23p4(1D)4p(2F) (335 nm) transitions...
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1,3-Di-<i>n</i>-butylthiourea
PublicationIn the title compound, C9H20N2S, the n-butyl groups are in syn and anti positions in relation to the C=S bond. In the crystal, two molecules are connected by two N-H···S=C hydrogen bonds into a centrosymmetric dimer. Another N-H···S=C hydrogen bond links the dimers, forming layers with a hydrophilic interior and a hydrophobic exterior, which spread across the (100) plane. Interlacing of the...
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Immunogenic and protective activity of recombinant chimeric Toxoplasma gondii proteins
PublicationToxoplasmosis, one of the most common parasitic invasions worldwide, may pose a great threat for individuals with weakened immune system. The parasite also causes considerable economic losses due to infection of livestock. To date there is no efficient immunoprophylaxis for humans and animals, which would provide long-lasting protection against T. gondii invasion. Chimeric proteins, containing several selected fragments of parasite...
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Multi-objective design of miniaturized impedance transformers by domain segmentation
PublicationFast multi-objective design optimization of compact microstrip impedance transformers is discussed. Our approach exploits approximation models constructed using sampled coarse- mesh EM simulation data in a partitioned design space and response correction techniques for design refinement. Demonstra
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PVA-Based Films with Strontium Titanate Nanoparticles Dedicated to Wound Dressing Application
PublicationBioactive materials may be applied in tissue regeneration, and an example of such materials are wound dressings, which are used to accelerate skin healing, especially after trauma. Here, we proposed a novel dressing enriched by a bioactive component. The aim of our study was to prepare and characterize poly(vinyl alcohol) films modified with strontium titanate nanoparticles. The physicochemical properties of films were studied,...
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Bioreactor shoot cultures of Rhododendron tomentosum (Ledum palustre) for a large-scale production of bioactive volatile compounds
PublicationRhododendron tomentosum Harmaja (Ledum palustre), a peat bog plant from Ericaceae family, has been used in traditional medicine as the anti-arthritis agent. Although modern researches confirm its anti-inflammatory properties, it remains threatened by habitat degradation and possibilities to collect this endangered species from its natural environment for further biological activity studies are limited. Therefore, R. tomentosum...
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Phospholipids as potential prevention factor in carcinogenesis
PublicationPhospholipids are a group of complex lipids, which can be used in cancer chemoprevention. Glicerophospholipids are composed of fatty acids esterified to a glycerol backbone, a phosphate group and a hydrophilic residue such as: cho- line, ethanoloamine, serine or inositol. In the sn-2 position of glicerophospholipid usually there are unsaturated fatty acids, i.e. linolenic acid, while in the sn-1 position more typi- cal are saturated...
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Dynamically positioned ship steering making use of backstepping method and artificial neural networks
PublicationThe article discusses the issue of designing a dynamic ship positioning system making use of the adaptive vectorial backstepping method and RBF type arti cial neural networks. In the article, the backstepping controller is used to determine control laws and neural network weight adaptation laws. e arti cial neural network is applied at each time instant to approximate nonlinear functions containing parametric uncertainties....
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A measurement method for lossy capacitive relative humidity sensors based on a direct sensor-to-microcontroller interface circuit
PublicationA new time-domain measurement method for determining the capacitance and resistance values of lossy relative humidity capacitive sensors is presented. The method is based on a direct sensor-to-microcontroller interface for microcontrollers with internal analog comparators and timers. The interface circuit consists only of four reference resistors (two reference resistors if a microcontroller includes a voltage reference source),...
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Rapid EM-driven antenna dimension scaling through inverse modeling
PublicationIn this letter, a computationally feasible technique for dimension scaling of antenna structures is introduced. The proposed methodology is based on inverse surrogate modeling where the geometry parameters of the antenna structure of interest are explicitly related to the operating frequency. The surrogate model is identified based on a few antenna designs optimized for selected reference frequencies. For the sake of computational...
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Evaluating Asymmetric N-Grams as Spell-Checking Mechanism
PublicationTypical approaches to string comparing marks two strings as either different or equal without taking into account any similarity measures. Being able to judge similarity is however required for spelling error corrections, as we want to find the best match for a given word. In this paper we present a bi2quadro-grams method for spelling errors correction. The method proposed uses different n-grams dimension for the source (checked)...
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Evaluating calibration and robustness of pedestrian detectors
PublicationIn this work robustness and calibration of modern pedestrian detectors are evaluated. Pedestrian detection is a crucial perception com- ponent in autonomous driving and here we study its performance under different image corruptions. Furthermore, we provide analysis of classifi- cation calibration of pedestrian detectors and we show a positive effect of using style-transfer augmentation technique. Our analysis is aimed as a step...
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Wave transmission across surface interfaces in lattice structures
PublicationWithin the lattice dynamics formulation, we present an exact solution for anti-plane surface waves in a square lattice strip with a surface row of material particles of two types separated by a linear interface. The considered problem is a discrete analog of an elastic half-space with surface stresses modelled through the simplified Gurtin–Murdoch model, where we have an interfacial line separating areas with different surface...
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The inhibition effect of mad Honey on corrosion of 2007-type aluminium alloy in 3.5% NaCl solution
PublicationThe inhibition effect of mad honey on corrosion of 2007-type aluminium alloy in 3.5% NaCl solution was investigated by Tafel extrapolarisation (TP), electrochemical impedance spectroscopy (EIS) and dynamic electrochemical impedance spectroscopy (DEIS). All the studied parameters exhibited good anti-corrosive properties against corrosion of 2007-type aluminium alloy in the test solution; the corrosion rates decreased with the increase...
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Cytochromes P450 and Skin Cancer: Role of Local Endocrine Pathways
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Anticancer Properties of Amino Acid and Peptide Derivatives of Mycophenolic Acid
PublicationBackground: Although Mycophenolic Acid (MPA) is applied as prodrugs in clinic as an immunosuppressant, it also possesses anticancer activity. MPA acts as Inosine-5’-Monophosphate Dehydrogenase (IMPDH) inhibitor, where the carboxylic group at the end of the side chain interacts with Ser 276 of the enzyme via hydrogen bonds. Therefore, MPA derivatives with other polar groups indicated high inhibition too. On the other hand, potent...
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Synthesis of Combretastatin A-4 Analogs and their Biological Activities
PublicationCombretastatin A-4 (CA-4) is a natural product, which consists of two phenyl rings, linked by an ethylene bridge. CA-4, inhibitor of polymerization of tubulin to microtubules, possesses a strong antitumor and anti-vascular properties both in vitro and in vivo. Previous studies showed that disodium phosphate salt of CA-4, a water-soluble prodrug is well tolerated at therapeutically useful doses. However, it should be noted that...
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Superexcited states in the vacuum-ultraviolet photofragmentation of isoxazole molecules
PublicationThe photofragmentation of isoxazole molecules producing excited atomic and molecular fragments has been investigated over the energy range 16-50 eV, using photon-induced fluorescence spectroscopy. The following fragments have been identified by their fluorescence: the excited hydrogen atoms H(n), n = 3-7 and the diatomic CH(A2Δ, B2Σ−), CN(B2Σ+) and C2(d3Πg) fragments. The diatomic fragments are vibrationally and highly rotationally...
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The Business Environment of Georgia and Ukraine: Approaches to a Comparative Analysis
PublicationThe formation of a favourable business environment and the intensification of entrepreneurial activity on this basis is one of the priorities of economic policy of governments around the world. The aim of this article is to conduct a comparative analysis of some of the characteristics of the business environment of Georgia and Ukraine. The theoretical basis of the study is the understanding of the business environment as a necessary...
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Bioactive Ingredients with Health-Promoting Properties of Strawberry Fruit (Fragaria x ananassa Duchesne)
PublicationStrawberries (Fragaria x ananassa Duchesne) belong to the berry group and are characterized primarily by delightful sensory properties. Due to their chemical composition, these fruits are a rich source of bioactive compounds that can modify the metabolic and physiological functions of the body. The aim of this work is to present the current state of research on bioactive ingredients found in these fruits in the context of their...
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The Chernobyl effect
PublicationThe 1986 Chernobyl catastrophe was not only a human and ecological disaster, but also a political-ideological one, severely discrediting Soviet governance and galvanizing dissidents in the Eastern Bloc. In the case of Poland, what began as isolated protests against the Soviet nuclear site grew to encompass domestic nuclear projects in general, and in the process spread across the country and attracted new segments of society. This...
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Improving flexibility and performance of PVM applications by distributed partial evaluation
PublicationA new framework for developing both flexible and efficient PVM applications is described. We propose Architecture Templates Interface (ATI) that allows to control application granularity and parallelism. To ensure high application efficiency we extend partial evaluation strategy into domain of distributed applications obtaining Distributed Partial Evaluation (DPE). Both ATI and DPE were implemented using a new distributed programming...
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Zastosowanie technik dwuwymiarowych w analizie frakcji lotnej i oznaczaniu związków bioaktywynych owoców jagody kamczackiej
PublicationDotychczasowe doniesienia literaturowe wskazują, że owoce strefy borealnej, do których należy popularna w Polsce aronia, są źródłem cennych składników odżywczych i prozdrowotnych. Podobnie jagoda kamczacka, należąca do tej grupy owoców, może stanowić źródło substancji istotnych dla ludzkiej diety. Jednakże aktualny stan wiedzy o składzie chemicznym owoców jagody kamczackiej ogranicza się głównie do informacji dotyczących całkowitej...
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Microstrip four-port circulator using a ferrite coupled line section
PublicationThis paper describes an alternative configuration of a four-port circulator realized in a microstrip ferrite coupled line technology. The proposed fully planar device employs two three-port circulators consisting of a ferrite coupled line junction and T junction. Both circulators are connected through the same arm, hence, the problem of anti-parallel magnetization met in this type of circulators is avoided without the increase...
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Electroanalytical and spectroscopic procedures for examination of interactions between double stranded DNA and intercalating drugs
PublicationPrzedstawiono metodę elektrochemicznego opisu oddziaływań dsDNA ze związkiem biologicznie czynnym w warunkach, w których zarówno badany związek jak i cząsteczka DNA są w roztworze elektrolitu. Opracowano warunki pomiaru, gdzie ani związek, ani DNA nie adsorbuje na elektrodzie. Wykazano, podobnie jak podczas badania innymi metodami, że oddziaływania są dwojakiego rodzaju: elektrostatyczne i poporzez interkalację.
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Wpływ warunków ciśnieniowej filtracji na przebieg biologicznego usuwania azotu amonowego z wody w procesie nitryfikacji = Effect of pressure filtration conditions on nitrification process used for ammonia nitrogen removal from water
PublicationW pracy przedstawiono wyniki badań laboratoryjnych nad wpływem podwyższonego, zmiennego ciśnienia (do 0,8 MPa) na przebieg usuwania azotu amonowego z wody na nitryfikacyjnym złożu filtracyjnym. Wykazano, że ani podwyższone ciśnienie, ani jego zmiany nie wpływają hamująco na przebieg procesów nitryfikacji. Stwierdzono pozytywny wpływ płukania filtrów biologicznych na usuwanie azotu amonowego z wody.
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Characterizing surface and air temperature in the Baltic Sea coastal area using remote sensing techniques and GIS
PublicationEstimation of surface temperature using multispectral imagery retrieved from satellite sensors constitutes several problems in terms of accuracy, accessibility, quality and evaluation. In order to obtain accurate results, currently utilized methods rely on removing atmospheric fluctuations in separate spectral windows, applying atmospheric corrections or utilizing additional information related to atmosphere or surface characteristics...
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Multiobjective Aerodynamic Optimization by Variable-Fidelity Models and Response Surface Surrogates
PublicationA computationally efficient procedure for multiobjective design optimization with variable-fidelity models and response surface surrogates is presented. The proposed approach uses the multiobjective evolutionary algorithm that works with a fast surrogate model, obtained with kriging interpolation of the low-fidelity model data enhanced by space-mapping correction exploiting a few high-fidelity training points. The initial Pareto...
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Zastosowanie programowania parametrycznego w planowaniu operacji obróbki elementów o powtarzalnej geometrii
PublicationPorównywano zastosowania dostępnych technik programowania obróbki numerycznej przedmiotów o powtarzających się elementach konstrukcji. Analizowano możliwości stosowania programowania parametrycznego w trybie programowania zorientowanego warsztatowo oraz pracy w środowisku systemu klasy CAM. Zwrócono uwagę na przejrzystość tworzonego programu w aspekcie możliwości jego edycji i korekty składni, formy zapisu programu w pamięci obrabiarki...
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Mass and momentum conservation in the simplified flood routing models
PublicationW pracy wykazano, że uproszczone modele fal wezbraniowych w postaci fali kinematycznej reprezentują w przypadku liniowych zarówno zasadę zachowania masy jaki i pędu, natomiast w przypadku nieliniowym, reprezentują albo zasadę zachowania masy albo pędu, zależnie od postaci zachowawczej równania. Ponadto wykazano, iż nieliniowa fala dyfuzyjna nie spełnia ani całkowowej zasady zachowania masy ani pędu.
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System wykrywania i przeciwdziałania spoofingowi GPS
PublicationSpoofing w systemach nawigacji satelitarnej jest atakiem elektronicznym, który polega na nieuprawnionej emisji sygnałów stanowiących imitacje rzeczywistych sygnałów odbieranych z satelitów. Powoduje on wyznaczenie nieprawidłowych informacji o czasie, położeniu i prędkości odbiornika. Z uwagi na trudność jego wykrycia, spoofing stanowi poważniejsze zagrożenie niż proste zagłuszanie sygnałów zakłóceniem o dużej mocy (ang. jamming)....
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Formation of CN (B2Σ+) radicals in the vacuum-ultraviolet photodissociation of pyridine and pyrimidine molecules
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Hydrogen migration in photodissociation of the pyridine molecules
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Hydrogen migration in formation of NH(A3Π) radicals via superexcited states in photodissociation of isoxazole molecules
PublicationFormation of the excited NH(A 3Π) free radicals in the photodissociation of isoxazole (C3H3NO) molecules has been studied over the 14-22 eV energy range using photon-induced fluorescence spectroscopy. The NH(A 3Π) is produced through excitation of the isoxazole molecules into higher-lying superexcited states. Observation of the NH radical, which is not a structural unit of the isoxazole molecule, corroborates the hydrogen atom...
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Elimination and migration of hydrogen in the vacuum-ultraviolet photodissociation of pyridine molecules
PublicationElimination of the excited hydrogen atoms H(n), n = 4–7, and hydrogen migration in formation of the excited NH(A 3Π) free radicals in the photodissociation of pyridine, C5H5N, molecules have been studied over the 17.5–70 eV photon energy range. In the measurements the photon-induced fluorescence spectroscopy technique has been applied. Both fragments are produced through excitation of pyridine molecules into higher-lying superexcited...
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Yields and Time-of-Flight Spectra of Neutral High-Rydberg Fragments at the K Edges of the CO2 Molecule
PublicationWe have studied the production of neutral fragments in high-Rydberg (HR) states at the C 1s and O 1s edges of the CO2 molecule by performing two kinds of experiments. First, the yields of neutral HR fragments were measured indirectly by ionizing such fragments in a static electric field and by collecting resulting singly charged positive ions as a function of the photon energy. Such measurements reveal not only excitations below...
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Extraction of antenna pattern from near field antenna measurements distorted by undesired emission
PublicationIn this paper authors present experimental correction of antenna pattern obtained from near field measurements when they are distorted by determined electromagnetic emission. Such situation may be met e.g. when feeding or supply subsystem interacts with antenna radiation pattern due to self-emission. Presented results of experiments show effectiveness of extraction of antenna pattern utilizing near field antenna measurements.
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Inhibitors of angiogenesis in cancer therapy – synthesis and biological activity
PublicationAngiogenesis is the process of formation of new capillaries from preexisting blood vessels. Angiogenesis is involved in normal physiological processes, and plays an important role in tumor invasion and development of metastases. Vascular endothelial growth factor (VEGF) plays a key role in angiogenesis. VEGF is a mitogen for vascular endothelial cells and stimulates their proliferation. By inhibiting the biological activity of...
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Modulation of CYP3A4 activity and induction of apoptosis, necrosis and senescence by the antitumor imidazoacridinone C-1311 in human hepatoma cells
PublicationThere is increasing evidence that the expression level of drug metabolic enzymes affects the final cellular response following drug treatment. Moreover, anti-tumour agents may modulate enzymatic activity and/or cellular expression of metabolic enzymes in tumour cells. We investigated the influence of CYP3A4 overexpression on the cellular response induced by the anti-tumour agent C-1311 in hepatoma cells. C-1311-mediated CYP3A4...
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Study on the accuracy of axle load spectra used for pavement design
PublicationWeigh-in-Motion (WIM) systems are used in order to reduce the number of overloaded vehicles. Data collected from WIM provide characteristics of vehicle axle loads that are crucial for pavement design as well as for the development of pavement distress prediction models. The inaccuracy of WIM data lead to erroneous estimation of traffic loads and in consequence inaccurate prediction of pavement distress process. The objective of...
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Variable Fractional Delay Filter Design Using a Symmetric Window
PublicationIn this paper a numerically efficient method for designing a nearly optimal variable fractional delay (VFD) filter based on a simple and well-known window method is presented. In the proposed method a single window extracted from the optimal filter with fixed fractional delay (FD) is divided into even and odd part. Subsequently, the odd part is discarded and symmetric even part of the extracted window is used to design a family...
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Theoretical consideration of free convective heat transfer from a round isothermal plate slightly inclined from the vertical
PublicationA semi-analytical solution of simplified Navier-Stokes and Fourier-Kirchhoff equations describing free convective heat transfer from a round isothermal surface slightly inclined from the vertical is presented. The solution is based on the assumption, typical for natural convection, that the velocity component normal to the surface is negligibly small in comparison to the tangential one. Next we neglect the nonlinear inertia force...
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Molecular basis of the low activity of antitumor anthracenediones, mitoxantrone and ametantrone, in oxygen radical generation catalyzed by NADH dehydrogenase. Enzymatic and molecular modelling studies
PublicationSyntetyczne antracenodionowe leki przeciwnowotworowe, w przeciwieństwie do antybiotyków antracyklinowych, charakteryzują się słabym wytwarzaniem wolnych rodników w układach z dehydrogenazą NADH. Wyniki prezentowane w artykule wskazują, że ani potencjał redukcyjny, ani konformacja łańcuchów bocznych, ani energie orbitali granicznych (LUMO i HOMO) nie determinują zdolności antracenedionów do stymulacji wytwarzania reaktywnych form...
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Sterowanie małą elektrownią wiatrową z wykorzystaniem efektu przeciągnięcia
PublicationW artykule przedstawiono sposób sterowania małą elektrownią wiatrową o zmiennej prędkości kątowej i o stałym kącie ustawienia łopat. Algorytmy sterowania przeniesione z dużych elektrowni wiatrowych nie zapewniają ani odpowiedniej sprawności aerodynamicznej ani bezpieczeństwa. Zaproponowany algorytm umożliwia zwiększenie wydajności o ponad 50% i zapewnienie bezpieczeństwa przy dużej prędkości wiatru przez wejście w stan przeciągnięcia....
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BIOMATERIALS AND IMPLANTS IN CARDIAC AND VASCULAR SURGERY - REVIEW
PublicationCurrently, on prosthesis in cardiac blood vessels and heart valves are used materials of animal or synthetic origin. For animal materials include, among others pericardial sac in which is the heart. Materials such as this (natural) are characterized by a remarkable biocompatibility within the human body, but their main disadvantage is the relatively low durability. In turn, synthetic materials, which include the austenitic chromium-nickel-molybdenum...
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Zabezpieczenia antykorozyjne stalowych barierek ochronnych na obiektach mostowych w ujęciu kosztów cyklu ich życia
PublicationThe article presents the Life Cycle Costs analysis of steel safety barriers operated in road lane conditions, located on a selected bridge structure. Three corrosion protection systems were proposed, analyzing them in terms of the cost of initial and planned outlays related to maintenance. Based on the LCC analysis for three options, taking into account the 25-year lifetime of the barriers, the optimal solutionwas indicated, i.e....
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Efficient FPGA Implementation of an RFIR Filter Using the APC–OMS Technique with WTM for High-Throughput Signal Processing
PublicationNowadays, Finite Impulse Response (FIR) filters are used to change the attributes of a signal in the time or frequency domain. Among FIR filters, a reconfigurable filter has the advantage of changing the coefficient in real-time, while performing the operation. In this paper, the Anti-Symmetric Product Coding (APC) and Odd Multiple Storage (OMS) modules are utilized to implement the reconfigurable FIR filter (RFIR–APC–OMS). Herein,...
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Determination of pharmaceuticals in fish: method optimization and occurrence in different species from Mediterranean rivers
PublicationThe multi-residue analytical method developed, based on accelerated solvent extraction, gel permeation chromatography purification and UPLC-MS/MS analysis allowed the simultaneous determination of 21 pharmaceuticals. Recoveries obtained for most of the target compounds were higher than 50%. The application of UPLC-MS/MS operating in the MRM mode, with two transitions monitored for each compound, provided good sensitivity and selectivity....