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Search results for: Genetic polymorphism
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System of monitoring of the Forest Opera in Sopot structure and roofing
PublicationThe authors present a solution realized in Forest Opera (name in Polish: Opera Leśna) in Sopot (Poland) in connection with the modernization and construction of a new roof. The complicated structure of the roof of the facility and the used covering in form of membrane made of technical fabric required (for security reasons) to install the unit of devices allowing for the continuous geodetic monitoring of the facility. Monitoring...
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Recombinant !ermostable AP Exonuclease from Thermoanaerobacter tengcongensis: Cloning, Expression, Purification, Properties and PCR Application
PublicationApurinic/apyrimidinic (AP) sites in DNA are considered to be highly mutagenic and must be corrected to preserve genetic integrity, especially at high temperatures. !e gene encoding a homologue of AP exonuclease was cloned from the thermophilic anaerobic bacterium Thermoanaerobacter tengcongensis and transformed into Escherichia coli. The protein product showed high identity (80%) to human Ape1 nuclease, whereas to E. coli exonuclease...
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Support for research biobanks among medical students in the Republic of Kazakhstan
PublicationBackground: Over the past few years, several biobanks have been organized in the Republic of Kazakhstan (RoK). As research biobanks are becoming an increasingly important tool for precision medicine, they require competent biobankers who will help disseminate the idea of biobanking throughout the society and support donation for research purposes. This study aimed to assess the support for research...
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Intra-operative biopsy in chronic sinusitis detects pathogenic Escherichia coli that carry fimG/H, fyuA and agn43 genes coding biofilm formation
PublicationThe aim of this study was to investigate whether or not surgical biopsy of sinus tissue in chronic sinusitis, not responsive to treatment, would detect E. coli. We intended to evaluate E. coli virulence genes, therefore dispute the causal role of such an unusual microorganism in chronic sinusitis, as well as consider effective pathogen-targeted therapy. Patients with E. coli isolated by intra-operative puncture biopsy were included...
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Transport deficiency is the molecular basis of Candida albicans resistance to antifungal oligopeptides
Publication(FMDP), an inhibitor of glucosamine-6-phosphate synthase, exhibited growth inhibitory activity against Candida albicans, with minimal inhibitory concentration values in the 0.05–50 mg/L range. Uptake by the peptide permeases was found to be the main factor limiting an anticandidal activity of these compounds. Di- and tripeptide containing FMDP (F2 and F3) were transported by Ptr2p/Ptr22p peptide transporters (PTR) and FMDP-containing...
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c-Myc inhibition and p21 modulation contribute to unsymmetrical bisacridines-induced apoptosis and senescence in pancreatic cancer cells
PublicationBackground Pancreatic cancer (PC) is one of the most aggressive cancers and is the seventh leading cause of cancer-related death worldwide. PC is characterized by rapid progression and resistance to conventional treatments. Mutations in KRAS, CDKN2A, TP53, SMAD4/DPC4, and MYC are major genetic alterations associated with poor treatment outcomes in patients with PC. Therefore, optimizing PC therapy is a tremendous challenge. Unsymmetrical...
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A non-adiabatic wavepacket dynamical study of the low energy chargetransfer process in the S3+ + H collision
PublicationThe collisional system S3+ + H?S2+ + H+ has been studied using a time-dependent wavepacket methodologyin two-dimensions. Using available potential energy surfaces and coupling matrix elementsobtained from multireference ab initio calculations, five non-adiabatically coupled electronic states of1P symmetry have been included in the dynamical simulations. The collision has been studied in thelow energy regime of 1-10 eV. The wavepacket...
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Pilot study of the influence of thermoplastic starch based polymer packaging material on the growth of diatom population in sea water environment
PublicationNovel polymeric packaging materials susceptible to environmentally friendly decomposition appeared on the global market. The paper is devoted to an investigation of the impact of degradable polymer packaging on marine life. The chosen polymer was a commercial packaging based on thermoplastic starch (TPS over 85%). The microorganism chosen was Phaeodactylum tricornutum diatom (identified in many aquatic reservoirs, with a tendency...
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A model of liquid film breakdown formed due to impingement of a two-phase jet on a horizontal surface
PublicationThe present work aims to provide an explanation to the phenomenon of breakdown of the thin liquid film created by impinging two-phase, liquid-gas jet. Existing in the literature models describe merely thebreakdown of single phase liquid films. The model presented here is based on examination of mass and energy equations under the applied criterion of the minimum of total energy. That allows to determinethe minimum thickness of...
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Jacek Krenz : City in my eyes
PublicationSketch City: Tips and Inspiration for Drawing on Location is the companion for any creative traveler, urban explorer, or budding artist. 50 artists scattered around the globe have been brought together to share tips about their favorite urban settings, including locations in South America, Europe, Canada, Asia, and beyond. Citified sketchers are guiding through techniques for capturing frenetic street scenes as well as the rare...
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New bulk liquid membrane oscillator composed of two coupled oscillators with diffusion-mediated physical coupling
PublicationA new type of bulk liquid membrane system, which represents the first example of a bulk liquid membrane oscillator characterised by the presence of two coupled oscillators, is described. When the benzyldimethyltetradecylammonium chloride surfactant undergoes an oscillatory mass transfer through a nitromethane liquid membrane, a new liquid layer (phase X) appears between the membrane and the acceptor phase. Kinetic analysis provides...
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Isolation of the GFA1 gene encoding glucosamine-6-phosphate synthase of Sporothrix schenckii and its expression in Saccharomyces cerevisiae
PublicationGlucosamine-6-phosphate synthase (GlcN-6-P synthase) is an essential enzyme involved in cell wall biogenesis that has been proposed as a strategic target for antifungal chemotherapy. Here we describe the cloning and functional characterization of Sporothrix schenckii GFA1 gene which was isolated from a genomic library of the fungus. The gene encodes a predicted protein of 708 amino acids that is homologous to GlcN-6-P synthases...
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Relikty słowiańskiej ludowości w poezji Syrokomli
PublicationThe paper discusses two models of reading the works by Władysław Syrokomla – one from the era of Positivism, the other – from the era of Young Poland. It displays the canvas of Polish dualism in the author’s poetry. The paper explains its lineage in terms of ethnogenesis. It shows the genesis as the evocation of primeval religious substance of Pre-Slavic origin. The paper refers to the findings of cultural anthropology and religious...
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Displacement measurements during load testing of railway arch bridge
PublicationThe paper discusses issues concerning load tests carried out on a twin-track, arch railway bridge over the Martwa Wisla river in Gdansk. Currently, it is the bridge with the longest span in its class in Poland. The load-bearing structure consists of three no-hinge arches and an orthotropic deck suspended from them. The studies of the structure assumed the performing of static and dynamic tests. The paper presents the method for...
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A Preliminary Study and Analysis of Tidal Stream Generators
PublicationFor a sustainable future, tidal energy can play a vital role. Tidal energy relies on the gravitational pull of the Moon and the Sun along with the centrifugal forces created by the Earth. Tidal barrage uses the potential energy from the tide and has been very successful in electricity production. With the help of a turbine, kinetic energy can also be harnessed from tidal currents to generate electricity. However, it is not economically...
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Modification of structured bio‑carbon derived from spongin-based scaffolds with nickel compounds to produce a functional catalyst for reduction and oxidation reactions: Potential for use in environmental protection
PublicationThree different 3D fibrous-like NiO/Ni(OH)2/Ni‑carbonized spongin-based materials were prepared via a simple sorption–reduction method. Depending on the support used, the catalysts were composed of carbon, nickel oxide, nickel hydroxide and zero-valent nickel, with the surface content of the nickel-containing phase in the range 15.2–26.0 wt%. Catalytic studies showed promising activity in the oxidation of phenolic compounds in water...
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Tworzenie miejskości po 1990r., Geneza niemieckiej urbanistyki współczesnych założeń mieszkaniowych
PublicationArtykuł jest przyczyną do przypomnienia genezy współczesnej formy niemieckich miejskich struktur mieszkaniowych w kontekście zmian rozumienia ich wymiaru miejskości. Niemiecka myśl urbanistyczna łączy w sobie dwie wyraziste tradycje dwudziestego wieku - Gründerzeit i KlassischeModerne. Pozostaje jednak silnie otwarta na innowację generowaną nie tylko dzięki postępowi technicznemu, ale przede wszystkim poprzez planowanie interdyscyplinarne...
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Graph Decomposition for Memoryless Periodic Exploration
PublicationWe consider a general framework in which a memoryless robot periodically explores all the nodes of a connected anonymous graph by following local information available at each vertex. For each vertex v, the endpoints of all edges adjacent to v are assigned unique labels within the range 1 to deg (v) (the degree of v). The generic exploration strategy is implemented using a right-hand-rule transition function: after entering vertex...
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Model of an Integration Bus of Data and Ontologies of Smart Cities Processes
PublicationThis paper presents a model of an integration bus used in the design of Smart Cities system architectures. The model of such a bus becomes necessary when designing high-level architectures, within which the silo processes of the organization should be seen from the perspective of its ontology. For such a bus to be used by any city, a generic solution was proposed which can be implemented as a whole or in part depending on the requirements...
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Rating by detection: an artifact detection protocol for rating EEG quality with average event duration
PublicationQuantitative evaluation protocols are critical for the development of algorithms that remove artifacts from real EEG optimally. However, visually inspecting the real EEG to select the top-performing artifact removal pipeline is infeasible while hand-crafted EEG data allow assessing artifact removal configurations only in a simulated environment. This study proposes a novel, principled approach for quantitatively evaluating algorithmically...
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Development of the System Assurance Reference Model for Generating Modular Assurance Cases
PublicationAssurance cases are structured arguments used to demonstrate specific system properties such as safety or security. They are used in many industrial sectors including automotive, aviation and medical devices. Larger assurance cases are usually divided into modules to manage the complexity and distribute the work. Each of the modules is developed to address specific goals allocated to the specific objects i.e. components of the...
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Rengel Cane Sia Doctoral Candidate
PeopleI'm Rengel, born and raised in the Philippines. As an undergraduate I did kinetic modeling on Copper-catalyzed atom transfer radical addition (ATRA). Then I was inspired to do both theoretical and experimental studies, which led me to propose my master's thesis on Synthesis, Computational, Electrochemical, and Photoconductivity Studies on Naphthalene and its derivatives. This led to a master's degree in Chemistry in the Mindanao...
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Optymalizacja zasobów chmury obliczeniowej z wykorzystaniem inteligentnych agentów w zdalnym nauczaniu
PublicationRozprawa dotyczy optymalizacji zasobów chmury obliczeniowej, w której zastosowano inteligentne agenty w zdalnym nauczaniu. Zagadnienie jest istotne w edukacji, gdzie wykorzystuje się nowoczesne technologie, takie jak Internet Rzeczy, rozszerzoną i wirtualną rzeczywistość oraz deep learning w środowisku chmury obliczeniowej. Zagadnienie jest istotne również w sytuacji, gdy pandemia wymusza stosowanie zdalnego nauczania na dużą skalę...
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A Multi-Fidelity Surrogate-Model-Assisted Evolutionary Algorithm for Computationally Expensive Optimization Problems
PublicationIntegrating data-driven surrogate models and simulation models of different accuracies (or fideli-ties) in a single algorithm to address computationally expensive global optimization problems has recently attracted considerable attention. However, handling discrepancies between simulation models with multiple fidelities in global optimization is a major challenge. To address it, the two major contributions of this paper include:...
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Balancing energy processes in turbine engines
PublicationThe article discusses the issue of balancing energy processes in turbine engines in operation in aeronautic and PDULQHSURSXOVLRQV\VWHPVZLWKWKHDLPWRDQDO\VHDQGHYDOXDWH EDVLFRSHUDWLQJSDUDPHWHUV7KH¿UVWSDUWSUHVHQWV the problem of enormous amounts of energy needed for driving fans and compressors of the largest contemporary turbofan engines commonly used in long-distance aviation. The amounts of the transmitted power and the effect RIÀRZSDUDPHWHUVDQGFRQVWUXFWLRQDOSURSHUWLHVRIWKHHQJLQHV RQWKHLUSHUIRUPDQFHDQGUHDOHI¿FLHQF\DUH evaluated....
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Thermal and hydraulic phenomena in boundary layer of minijets impingement on curved surfaces
PublicationPresented work considers flow and thermal phenomena occurring during the single minijet impingement on curved surfaces, heated with a constant heat flux, as well as the array of minijets. Numerical analyses, based on the mass, momentum and energy conservation laws, were conducted, regarding single phase and two-phase simulations. Focus was placed on the proper model construction, in which turbulence and boundary layer modeling...
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THE PANTOGRAPH AND ITS GEOMETRIC TRANSFORMATIONS - A FORMER POPULAR TOOL FOR COPYING AND SCALING
PublicationDevelopment of digital technology has resulted in significant transformations of designer workshops. Computer applications replaced the previously existing tools and methods for drawing up of projects. Professional, sophisticated drawing instruments and tools for manual plotting, as well as basic drawing aids, have gradually fallen into oblivion and become relicts of a bygone era - the objects of collectors' interest. Gdansk University...
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Influence of reactive oxygen species during deposition of iron oxide films by high power impulse magnetron sputtering.
PublicationIron oxide films were deposited using high power impulse magnetron sputtering (HiPIMS) of an iron cathode in an argon/oxygen gas mixture at different gas pressures (0.5~Pa, 1.5~Pa, and 5.0~Pa). The HiPIMS system was operated at a repetition frequency $f = 100$~Hz with a duty cycle of 1~\%. A main goal is a comparison of film growth during conventional and electron cyclotron wave resonance-assisted HiPIMS. The deposition plasma...
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Evaluation of Three Peptide Immobilization Techniques on a QCM Surface Related to Acetaldehyde Responses in the Gas Phase
PublicationThe quartz-crystal microbalance is a sensitive and universal tool for measuring concentrations of various gases in the air. Biochemical functionalization of the QCM electrode allows a label-free detection of specific molecular interactions with high sensitivity and specificity. In addition, it enables a real-time determination of its kinetic rates and affinity constants. This makes QCM a versatile bioanalytical screening tool for...
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The application of Monod equation to denitrification kinetics description in the moving bed biofilm reactor (MBBR)
PublicationIn this paper, the kinetic constants Vmax and KCOD occurring in the Monod equation, which describe the denitrification process in the moving bed, are determined. For this purpose, a laboratory moving bed biofilm reactor (MBBR) was used. The filling of the reactor consisted of EvU Perl carriers. The experiment was carried out with an excess of nitrate, and denitrification rate was dependent on the concentration of external organic...
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Integration of Multi-Source Geospatial Data from GNSS Receivers, Terrestrial Laser Scanners, and Unmanned Aerial Vehicles
PublicationThe analysis based on geospatial data from different measurement systems now constitutes a complex numerical and practical enterprise. The dynamic development of modern technologies enables rapid and precise acquisition of such data. Nonetheless, the diversity of reference systems is today one of the main challenges for their correct interpretation. The combined use of the processed measurement results and archival data in paper...
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A study of cavitation erosion resistance of an ion nitrided titanium alloy by means of the vibration and rotating disk methods
PublicationIn this work, a comparative analysis of the cavitation erosion resistance of the Ti– 6.7Al–2.5Mo–1.8Cr–0.5Fe–0.25Si alloy (known as brand VT3-1) before and after lowtemperature ion nitriding is carried out. Two test methods were applied, using vibrative (ASTM G-32) and rotating disk rigs, respectively. The kinetic dependences of the erosive destruction of samples of titanium alloy VT3-1 in the initial state, after ion nitriding...
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Application of Least Squares with Conditional Equations Method for Railway Track Inventory Using GNSS Observations
PublicationSatellite geodetic networks are commonly used in surveying tasks, but they can also be used in mobile surveys. Mobile satellite surveys can be used for trackage inventory, diagnostics and design. The combination of modern technological solutions with the adaptation of research methods known in other fields of science offers an opportunity to acquire highly accurate solutions for railway track inventory. This article presents the...
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Comprehensive methodology for Staphylococcus aureus lipidomics by liquid chromatography and quadrupole time-of-flight mass spectrometry
PublicationStaphylococcus aureus is a common pathogen known to cause relatively minor infections as well as severe disorders in humans. Although there is fair amount of published data concerning various aspects of its biology, epidemiology, genetics, etc., there is still a scarce amount of data presenting reliable and thorough investigations regarding high-throughput analysis of total S. aureus lipid content. Therefore, the aim of this study...
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Algorithms and Tools for Intelligent Control of Critical Infrastructure Systems
PublicationCritical Infrastructure Systems (CIS) are spatially distributed and of a network structure. The dynamics are nonlinear, uncertain and with several time scales. There is a variety of different objectives to be reliably met under a wide range of operational conditions. The operational conditions are influenced by the disturbance inputs, operating ranges of the CIS, faults in the sensors and actuators and abnormalities occurring in...
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Integrated monitoring, control and security of Critical Infrastructure Systems
PublicationModern societies have reached a point where everyday life relies heavily on desired operation of critical infrastructures, in spite of accidental failures and/or deliberate attacks. The issue of desired performance operation of CIS at high security level receives considerable attention worldwide. The pioneering generic methodologies and methods are presented in the paper project for designing systems capable of achieving these...
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Unbounded quantum advantage in communication complexity measured by distinguishability
PublicationCommunication complexity is a fundamental aspect of information science, concerned with the amount of communication required to solve a problem distributed among multiple parties. The standard quantification of one-way communication complexity relies on the minimal dimension of the communicated systems. In this paper, we measure the communication complexity of a task by the minimal distinguishability required to accomplish it,...
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Approximation Strategies for Generalized Binary Search in Weighted Trees
PublicationWe consider the following generalization of the binary search problem. A search strategy is required to locate an unknown target node t in a given tree T. Upon querying a node v of the tree, the strategy receives as a reply an indication of the connected component of T\{v} containing the target t. The cost of querying each node is given by a known non-negative weight function, and the considered objective is to minimize the total...
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Expedited EM-Driven Design of Miniaturized Microwave Hybrid Couplers Using Surrogate-Based Optimization
PublicationMiniaturization of microwave hybrid couplers is important for contemporary wireless communication engineering. Using standard computer-aided design methods for development of compact structures is extremely challenging due to a general lack of computationally efficient and accurate simulation models. Poor accuracy of available equivalent circuits results from neglecting parasitic cross-couplings that greatly affect the performance...
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Advanced Control With PLC—Code Generator for aMPC Controller Implementation and Cooperation With External Computational Server for Dealing With Multidimensionality, Constraints and LMI Based Robustness
PublicationThe manufacturers of Programmable Logic Controllers (PLC) usually equip their products with extremely simple control algorithms, such as PID and on-off regulators. However, modern PLCs have much more efficient processors and extensive memory, which enables implementing more sophisticated controllers. The paper discusses issues related to the implementation of matrix operations, time limitations for code execution within one PLC...
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Inverse Modeling and Optimization of CSRR-based Microwave Sensors for Industrial Applications
PublicationDesign optimization of multivariable resonators is a challenging topic in the area of microwave sensors for industrial applications. This paper proposes a novel methodology for rapid re-design and parameter tuning of complementary split-ring resonators (CSRRs). Our approach involves inverse surrogate models established using pre-optimized resonator data as well as analytical correction techniques to enable rapid adjustment of geometry...
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Swapping Space for Time: An Alternative to Time-Domain Interferometry
PublicationYoung's double-slit experiment [1] requires two waves produced simultaneously at two different points in space. In quantum mechanics the waves correspond to a single quantum object, even as complex as a big molecule. An interference is present as long as one cannot tell for sure which slit is chosen by the object. The more we know about the path, the worse the interference. In the paper we show that quantum mechanics allows for...
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The topography of Bi2VO5.5 ceramic measured with SEM and confocal microscope
Open Research DataThe topography of Bi2VO5.5 ceramics was measured by SEM and confocal microscope.
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Complex multidisciplinary optimization of turbine blading systems
PublicationThe paper describes the methods and results of direct optimization of turbine blading systems using a software package Opti_turb. The final shape of the blading is obtained from minimizing the objective function, which is the total energy loss of the stage, including the leaving energy. The current values of the objective function are found from 3D RANS computations (from a code FlowER) of geometries changed during the process...
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Testing Stability of Digital Filters Using Optimization Methods with Phase Analysis
PublicationIn this paper, novel methods for the evaluation of digital-filter stability are investigated. The methods are based on phase analysis of a complex function in the characteristic equation of a digital filter. It allows for evaluating stability when a characteristic equation is not based on a polynomial. The operation of these methods relies on sampling the unit circle on the complex plane and extracting the phase quadrant of a function...
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Host and pathogen factors in Klebsiella pneumoniae upper urinary tract infections in renal transplant patients
PublicationPurpose . To analyse the role of virulence factors (VFs) and host in Klebsiella pneumoniae upper urinary tract infections (UTIs) in renal transplant (RTx) recipients. Methodology. Clinical and demographic data were registered prospectively. Phylogenetic background of K. pneumoniae isolates was analysed by PCR melting profiles (MP) and the following VFs genes: fimH-1, uge, kpn, ycfM, mrkD, rmpA, magA, hlyA, cnf-1, irp-1, irp-2,...
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Marine and Cosmic Inspirations for AI Algorithms
PublicationArtificial Intelligence (AI) is a scientific area that currently sees an enormous growth. Various new algorithms and methods are developed and many of them meets practical, successful applications. Authors of new algorithms draw different inspirations. Probably the most common one is the nature. For example, Artificial Neural Networks were inspired by the structure of human brain and nervous system while the classic Genetic Algorithm...
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Karol Rudziński inż.
PeopleKarol Rudziński (born on August 18, 1979 in Inowrocław). After graduating from Shipbuilding Technical School in Gdańsk, he continued his studies at Faculty of Mechanical Engineering of Gdańsk University of Technology. He graduated in 2007 engineering studies in specialization: Mechanics and Machine Building, Machine Technology. In 2002, he started working at Faculty of Hydro and Environmental Engineering at Gdańsk University of...
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Andrzej Chybicki dr inż.
PeopleA graduate of the Faculty of Electronics, Telecommunications and Informatics at the Gdańsk University of Technology, PhD in technical sciences in the field of IT specializing in distributed data processing in IT . Aimed at exploiting the achievements and knowledge in the field of industrial research. He cooperated with a number of companies including OpeGieka Elbląg, Reson Inc., Powel Sp. z o. o., Wasat, Better Solutions, the European...
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Magdalena Szuflita-Żurawska
PeopleHead of the Scientific and Technical Information Services at the Gdansk University of Technology Library and the Leader of the Open Science Competence Center. She is also a Plenipotentiary of the Rector of the Gdańsk University of Technology for open science. She is a PhD Candidate. Her main areas of research and interests include research productivity, motivation, management of HEs, Open Access, Open Research Data, information...