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Peptide dendrimers as antifungal agents and carriers for potential antifungal agent—N3‐(4‐methoxyfumaroyl)‐(S)‐2,3‐ diaminopropanoic acid—synthesis and antimicrobial activity
PublikacjaA series of peptide dendrimers and their conjugates with antimicrobial agent FMDP (N3‐(4‐methoxyfumaroyl)‐(S)‐2,3‐diamino‐propanoic acid) were synthesized. The obtained compounds were tested for the antibacterial and antifungal activity. All novel dendrimers displayed much better activity against the tested strains than FMDP itself. Moreover, their conjugates with FMDP also exhibited antimicrobial activity. The most promising molecules...
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DESIGNING OF PARKING SPACES TAKING INTO ACCOUNT THE PARAMETERS OF DESIGN VEHICLES IN RUSSIA
PublikacjaNowadays, in all the cities, there is an acute problem of a lack of parking spaces. The number of vehicles are becoming more and more larger, not only in megacities, but in small cities of the country, as well and there are no more parking places - the pace of solving the problem is several times slower than the rate of the transport growth among the citizens. The article is dedicated to the determination of the optimum sizes parking...
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Detection, identification and determination of resveratrol in wine. Problems and challenges
PublikacjaResveratrol is a compound synthesized by plants in response to unfavorable conditions of growth like mechanical injury, siege of bacteria or fungi and UV exposure. It is concentrated mostly in grapes skin and further more in the products made from grapes especially red wines. Each wine is characterized by different amount of given stilbene since its occurrence is affected by many factors like: types of grapes, environment (climate,...
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SMART GRID TECHNOLOGIES IN ELECTRIC POWER SUPPLY SYSTEMS OF PUBLIC TRANSPORT
PublikacjaNowadays the issue of electric energy saving in public transport is becoming a key area of interest which is connected both with a growth in environmental awareness of the society and an increase in the prices of fuel and electricity. It can be achieved by improving the usage of regenerative breaking. In 2016 the Przedsiębiorstwo Komunikacji Trolejbusowej (PKT, Trolleybus Transport Company) in Gdynia began practical implementation...
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Planning a Cost-Effective Delay-Constrained Passive Optical Network for 5G Fronthaul
PublikacjaWith the rapid growth in the telecommunications industry moving towards 5G and beyond (5GB) and the emergence of data-hungry and time-sensitive applications, Mobile Network Operators (MNOs) are faced with a considerable challenge to keep up with these new demands. Cloud radio access network (CRAN) has emerged as a cost-effective architecture that improves 5GB performance. The fronthaul segment of the CRAN necessitates a high-capacity...
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The biological role of prolyl oligopeptidase and the procognitive potential of its peptidic inhibitors from food proteins
PublikacjaProlyl oligopeptidase (POP) is a conserved serine protease belonging to proline-specific peptidases. It has both enzymatic and non-enzymatic activity and is involved in numerous biological processes in the human body, playing a role in e.g., cellular growth and differentiation, inflammation, as well as the development of some neurodegenerative and neuropsychiatric disorders. This article describes the physiological and pathological...
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Sulfate reducing ammonium oxidation (SULFAMMOX) process under anaerobic conditions
PublikacjaSulfate (SO42-) can be an electron acceptor for ammonium nitrogen (NH4+) oxidation under anaerobic conditions. The process is known as sulfammox and can be a viable alternative to conventional, nitrite (NO2-) dependent, anammox. Two bacterial species, including Bacillus Benzoevorans and Brocadia Anammoxoglobus Sulfate, can perform that process. With sulfammox, an economically inefficient pre-nitration step (due to aeration) is...
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Within- and between-firm wage inequalities and trade integration in GVC
PublikacjaThis paper examines between- (inter) and within- (intra) firm wage inequality using rich employer-employee data for 12 European countries. We confirm that much overall wage inequality is observed within sectors and within occupations. The share of the within- and between-firm components in overall wage inequality varies across countries. We estimate the link between involvement in global value chains (GVCs) and wages differentiating...
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Software-Defined NB-IoT Uplink Framework - The Design, Implementation and Use Cases
PublikacjaIn the radiocommunication area, we may observe a rapid growth of new technology, such as 5G. Moreover, all the newly introduced radio interfaces, e.g., narrowband Internet of Things (NB-IoT), are strongly dependent on the software. Hence, the radiocommunication software development and optimization, as well as the 3GPP technical specification, should be introduced at the academic level of education. In this paper, a software-defined...
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Unraveling a novel microwave strategy to fabricate exposed {001}/{101} facets anatase nanocrystals: Potential for use to the elimination of environmentally toxic metronidazole waste
PublikacjaThis study present a novel microwave strategy to fabricate highly active anatase particles, exposing {101} and {001} facets. Microwave treatment time was shown to determine the growth of crystals in a certain direction. To the best of our knowledge, it is the first report revealing that the contact time of TiO2 crystals with fluorine ions during the microwave process affects the formed morphology, in particular exposed facets ratio....
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Learning design of a blended course in technical writing
PublikacjaBlending face-to-face classes with e-learning components can lead to a very successful outcome if the blend of approaches, methods, content, space, time, media and activities is carefully structured and approached from both the student’s and the tutor’s perspective. In order to blend synchronous and asynchronous e-learning activities with traditional ones, educators should make them inter-dependent and develop them according to...
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Real and Virtual Instruments in Machine Learning – Training and Comparison of Classification Results
PublikacjaThe continuous growth of the computing power of processors, as well as the fact that computational clusters can be created from combined machines, allows for increasing the complexity of algorithms that can be trained. The process, however, requires expanding the basis of the training sets. One of the main obstacles in music classification is the lack of high-quality, real-life recording database for every instrument with a variety...
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Proton Transfer Reaction Mass Spectrometry for Plant Metabolomics
PublikacjaVolatile organic compounds (VOCs) emitted by plants are a valuable source of information on their growth, theirresponse to stress, and the condition of their habitat. The recent trend in the analysis of low-mass molecules ofplant origin is metabolomics, which in the context of volatiles is often referred to as volatolomics. It requires theuse of modern analytical instrumentation...
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The linkage between knowledge risk management and organizational performance
PublikacjaThe purpose of this study is to examine the effect of knowledge risk management (KRM) on organizational performance, with measures considered as “softer” measures of performance, i.e. innovativeness, responsiveness, sustainability, and agility. Data were collected using an online questionnaire sent to private and public orga- nizations located all over the world. The analysis and hypotheses testing were performed using structural...
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Ciprofloxacin-modified degradable hybrid polyurethane-polylactide porous scaffolds developed for potential use as an antibacterial scaffold for regeneration of skin
PublikacjaThe aim of the performed study was to fabricate an antibacterial and degradable scaffold that may be used in the field of skin regeneration. To reach the degradation criterion for the biocompatible polyurethane (PUR), obtained by using amorphous α,ω-dihydroxy(ethylene-butylene adipate) macrodiol (PEBA), was used and processed with so-called “fast-degradable” polymer polylactide (PLA) (5 or 10 wt %). To meet the antibacterial requirement...
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Smart Blue Cities
PublikacjaThis paper presents the concept of Smart Cities from the perspective of those located by water, considering if there are more major differences in the way the concept is implemented in coastal cities, as opposed to those located anywhere else. It proves possible to point to such differences, in relation to the three key areas of mobility, the environment and living. Further consideration is given to specific legal and cross-cultural...
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Synthesis and biological evaluation of N-acylated tyramine sulfamates containing C-F bonds as steroid sulfatase inhibitors
PublikacjaSteroid sulfatase (STS) is responsible for the hydrolysis of biologically inactive sulfated steroids into their active un-sulfated forms and promotes the growth of various hormone-dependent cancers (e.g., breast cancer). Therefore, the STS enzyme is a promising therapeutic target for the treatment of steroid-sensitive cancers. Herein, we report the synthesis and biological evaluation of sulfamate analogs as potential STS inhibitors...
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Diamond-Phase (Sp3-C) Rich Boron-Doped Carbon Nanowalls (Sp2-C): A Physico-Chemical And Electrochemical Properties
PublikacjaThe growth of B-CNW with different boron doping levels controlled by the [B]/[C] ratio in plasma, and the influence of boron on the obtained material’s structure, surface morphology, electrical properties and electrochemical parameters, such as -ΔE and k°, were investigated. The fabricated boron-doped carbon nanowalls exhibit activity towards ferricyanide redox couple, reaching the peak separation value of only 85 mV. The flatband...
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Chloroacridine derivatives as potential anticancer agents which may act as tricarboxylic acid cycle enzyme inhibitors
PublikacjaThe chloroacridines affect biological forms of melanoma in different ways. Amelanotic (Ab) melanoma (with inhibited melanogenesis and higher malignancy) was particularly sensitive to the action of the chloroacridines. The Ab melanoma cells died through apoptosis and through death without caspase activation. Diminished activity of TAC enzymes was noticed among Ab melanoma cells together with ATP/NAD depletion, especially in the...
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Simple Superstrate Antenna for Connectivity Improvement in Precision Farming Applications
PublikacjaIn this paper, a concept of a simple circularly polarized antenna with partially reflecting surface (PRS) has been adopted for precision farming applications. The investigation contains an analysis of the dependence of the antenna performance on the elements number in the PRS structure in X- and Ka-band frequencies. Especially meaningful parameters from point-to-point connectivity perspective are...
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Design and investigations of a micro-turbine flow part
Publikacja-generative micro-power plant with the HFE7100 as a working medium was designed and built for experimental investigations. The heat output of the plant was assumed equal to 20 kW, while the electric output amounted to about 3kW.In the paper a multi-stage micro-turbine with partial admission of all the stages is described in detail and the results of the particular experimental investigations and numerical calculations are shown,...
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On nonlinear dilatational strain gradient elasticity
PublikacjaWe call nonlinear dilatational strain gradient elasticity the theory in which the specific class of dilatational second gradient continua is considered: those whose deformation energy depends, in an objective way, on the gradient of placement and on the gradient of the determinant of the gradient of placement. It is an interesting particular case of complete Toupin–Mindlin nonlinear strain gradient elasticity: indeed, in it, the...
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Energy Security of Polish Consumers in 2004-2021
Dane BadawczeEnergy security is one of the most important components of economic security. It is influenced not only by access to energy sources and the economic situation of the state and the individual consumer. In the years 2004–2021, energy security of the individual consumer in the economic dimension significantly improved. This was due to several factors:1....
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The Antimicrobial Potential of Bacteria Isolated from Honey Samples Produced in the Apiaries Located in Pomeranian Voivodeship in Northern Poland
PublikacjaThe principal objective of this study was to determine whether the honeys produced in apiaries located in Pomeranian Voivodeship (Northern Poland) contain bacteria producing metabolites with growth inhibition potential against important human and animal pathogens. The pathogens included Staphylococcus aurues, Staphyloccocus epidermidis, Escherichia coli, Listeria monocytogenes, Pseudomonas aeruginosa, and Candida albicans. From...
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Novel Research on Biomedical Polyurethanes
PublikacjaThe variety of mechanical properties characterizes properly designed PURs. They may be biocompatible and reveal compatibility with blood, making them attractive materials for the fabrication of tissue scaffolds; however, like all synthetic materials, PURs don’t reveal sufficient biocompatibility. PURs may undergo certain chemical modifications (e.g., 1,4:3,6-dianhydro-D-sorbitol, ascorbic acid (AA), growth factors, covering with...
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Regulation of LPS assembly via controlled proteolysis and sensing of LPS stress in Escherichia coli
PublikacjaLipopolysaccharide (LPS) is a complex glycolipid, essential for the bacterial viability and along with phospholipids, it constitutes the major amphiphilic component of outer membrane (OM) in most of the Gram-negative bacteria, including Escherichia coli. LPS molecules confer an effective permeability barrier to the OM and play a crucial role in bacteria-environment and -host interactions. The synthesis and accumulation of this...
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Advancing sustainable wastewater management: A comprehensive review of nutrient recovery products and their applications
PublikacjaWastewater serves as a vital resource for sustainable fertilizer production, particularly in the recovery of nitrogen (N) and phosphorus (P). This comprehensive study explores the recovery chain, from technology to final product reuse. Biomass growth is the most cost-effective method, valorizing up to 95 % of nutrients, although facing safety concerns. Various techniques enable the recovery of 100 % P and up to 99 % N, but challenges...
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Wpływ zastosowania nakładek wzmacniających środnik na nośność i sztywność doczołowego węzła śrubowego.
PublikacjaCiągłe dążenie do upraszczania elementów konstrukcyjnych oraz znajdowania mniej czasochłonnych rozwiązań wykonawczo – montażowych wraz z nieuchronnym wzrostem kosztów robocizny determinują m.in. eliminację z procesów technologicznych tych etapów, które nie podlegają automatyzacji. Taką czynnością jest przede wszystkim spawanie dodatkowych wzmocnień i usztywnień węzłów w postaci żeber. Efektem wieloletnich badań jest metoda przedstawiona...
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Wartość dodana akademickiej biblioteki „mobilnej” w kontekście programu Erasmus+ na przykładzie Biblioteki Politechniki Gdańskiej
PublikacjaMobilność wynikająca z założeń programu Erasmus+ w uczelniach i bibliotekach akademickich to wszelkie działania polegające na realizowaniu zagranicznych wyjazdów szkoleniowych w tzw. stażowych miejscach docelowych w krajach-sygnatariuszach programu. Erasmus+ w bibliotekach akademickich umożliwia szeroko pojęte doskonalenie zawodowe, rezultatem którego może być uzyskana wartość dodana uwidoczniona w nabywaniu nowych doświadczeń...
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On rotational instability within the nonlinear six-parameter shell theory
PublikacjaWithin the six-parameter nonlinear shell theory we analyzed the in-plane rotational instability which oc- curs under in-plane tensile loading. For plane deformations the considered shell model coincides up to notations with the geometrically nonlinear Cosserat continuum under plane stress conditions. So we con- sidered here both large translations and rotations. The constitutive relations contain some additional mi- cropolar parameters...
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Influence of Laser Modification on the Surface Character of Biomaterials: Titanium and Its Alloys—A Review
PublikacjaLaser surface modification is a widely available and simple technique that can be applied to different types of materials. It has been shown that by using a laser heat source, reproducible surfaces can be obtained, which is particularly important when developing materials for medical applications. The laser modification of titanium and its alloys is advantageous due to the possibility of controlling selected parameters and properties...
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Convergence or divergence in the European Union
PublikacjaThe disparities in economic prosperity revealed both from inter-country and inter-region perspective are one of the main problem in the modern economy. They consist of the dispersion in the real values such as incomes, GDP or productivity, but also nominal values such as prices and costs. The European Union is aware of this problem hence the role of the regional and structural policy aiming enhancing the cohesion between member...
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Fracture in composite/aluminium joints of variable adhesive properties
PublikacjaA strain gauge technique recently developed with the wedge test, for estimating crack length and, thus, the fracture energy of structural adhesive bonding, has been employed on a system in which one adherend had two types of surface treatment. Simple polishing and polishing with subsequent sandblasting were the treatments used, with a distinct straight line, perpendicular to the sample edges, separating the two. Despite the clear-cut...
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Genetic predisposition to inflammatory bowel disease
PublikacjaInflammatory bowel disease (IBD) is a chronic, incurable inflammatory disease of the digestive system. The two main disease entities included in the IBD are ulcerative colitis and Crohn's disease. According to epidemiological studies there are more and more new cases every year. In especially among the youngest patients with symptoms of malnutrition and growth inhibition to land up in hospitalwith cancer suspected. The purpose...
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Export diversification and dependence on natural resources
PublikacjaLow export diversification is a risk-augmenting factor for many countries dependent on natural resources. The literature tends to focus on the growth effects of resource dependence (‘resource curse’ debate) while not much is known on how it affects the variety of non-resource exports. To quantify this effect we decompose the relative Theil index using product-level export data from 160 countries over the time period 1996–2018....
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Insights into Seawater Biodegradation of Sustainable Mater-Bi/Poly(ε-caprolactone)-Based Biocomposites Filled with Diisocyanate-Modified Cellulose Particles
Publikacja: Due to rapid economic growth, the use of plastics in almost all areas of human life has significantly increased over recent decades, leading to massive pollution. Therefore, works dealing with sustainable and biodegradable polymer materials are vital now. Herein, sustainable MaterBi/poly(ε-caprolactone) (PCL)-based biocomposites, filled with diisocyanate-modified cellulose particles, were prepared and subjected to 12-week seawater...
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The Antibacterial and Antifungal Textile Properties Functionalized by Bimetallic Nanoparticles of Ag/Cu with Different Structures
PublikacjaWe reported a preparation and characterization of five kinds of impregnation solutions, containing Ag/Cu in the formof bimetallic nanoparticles (alloy and core-shell) as well as ionic species. The cotton-polyester textiles were successfully impregnated during the washing and ironing process by as-prepared solutions to have antibacterial and antifungal properties against to Escherichia coli, Staphylococcus aureus, and Candida albicans....
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Development of chromatographic and mass spectrometry conditions for untargeted lipidomic analysis of human breast milk
PublikacjaHuman breast milk (HBM) is a complex biofluid containing components which are essential for the proper growth of the newborn (for example nutrients such as carbohydrates, proteins, lipids) and also bioactive substances. According to the literature, most of studies involving HBM nutrients investigations focused essentially on the determination of proteins. The molecular composition of lipids in HBM is not well known as the protein...
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On Symmetry of Uniform and Preferential Attachment Graphs
PublikacjaMotivated by the problem of graph structure compression under realistic source models, we study the symmetry behavior of preferential and uniform attachment graphs. These are two dynamic models of network growth in which new nodes attach to a constant number m of existing ones according to some attachment scheme. We prove symmetry results for m=1 and 2 , and we conjecture that for m≥3 , both models yield asymmetry with high...
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Influence of reactive oxygen species during deposition of iron oxide films by high power impulse magnetron sputtering.
PublikacjaIron oxide films were deposited using high power impulse magnetron sputtering (HiPIMS) of an iron cathode in an argon/oxygen gas mixture at different gas pressures (0.5~Pa, 1.5~Pa, and 5.0~Pa). The HiPIMS system was operated at a repetition frequency $f = 100$~Hz with a duty cycle of 1~\%. A main goal is a comparison of film growth during conventional and electron cyclotron wave resonance-assisted HiPIMS. The deposition plasma...
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Typology of towns in the peripheries of Polish coastal regions: conclusions for urban policy
PublikacjaPeripheries means the land outside metropolitan areas. One of the main problemsin these areas is a lack of growth factors. Some towns can contribute to the developmentof these regions, because there are few such factors, and it is easier to create the newones, especially in urban policy.The subject of this paper is a typology of towns within the Polish peripheral coastalregions, limited to towns with more than 5 thousand inhabitants....
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Sound engineering as our commitment to its creators in Poland
PublikacjaSound engineering is an interdisciplinary and rapidly expanding domain. It covers many aspects, such as sound perception, studio and sound mastering technology, music information retrieval including content-based search systems and automatic music transcription frameworks, sound synthesis, sound restoration, electroacoustics, and other ones constituting multimedia technology. Moreover, machine learning methods applied to the topics...
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Miasta na prawach powiatu z rozwiniętym przemysłem jako lokalne ośrodki rozwoju na obszarach peryferyjnych polskich regionów
PublikacjaMost of the growth factors is situated in big cities, especially in metropolitan areas. Questions arise: 1) Whether and what development factors are in the peripheral areas of voivodeships (i.e. outside the functional areas of their capitals)? 2) Can the industry be the driving force of the development of these areas? These questions are related to the discussion on the reindustrialisation of the European Union and the role of...
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“Green” nature of the process of derivatization in analytical sample preparation
PublikacjaNowadays, the idea of Green Analytical Chemistry (GAC) is of high importance what impacts on the rapid growth in the sample preparation area with special emphasis on sample preparation simplification, miniaturization, and automation. Because the derivatization process is often an essential element of the analytical procedure, it should be important to focus on this issue from GAC perspective and conduct a series of experiments...
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Sustainable urban planning in the context of studentification of the inner city areas
PublikacjaThe social dimension of urban planning as well as the importance of local communities and civic participation are often underlined in contemporary urban renewal and revitalisation programmes based on the principles of sustainable development. British Urban Renaissance is one the most far-reaching and widely discussed urban regeneration strategies which aims at repopulation and social diversification of inner city areas and land...
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Specificity of Infant Digestive Conditions: Some Clues for Developing Relevant In Vitro Models
PublikacjaDigestion of nutrients is an essential function of the newborn infant gut to allow growth and development and understanding infant digestive function is essential to optimize nutrition and oral drug delivery. Ethical considerations prohibit invasive in vivo trials and as a consequence in vitro assays are often conducted. However, the choice of in vitro model parameters are not supported by an exhaustive analysis of the literature...
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Gas Composition Influence on the Properties of Boron-Doped Diamond Films Deposited on the Fused Silica
PublikacjaThe main subject of this study are molecular structures and optical properties of boron-doped diamond films with [B]/[C] ppm ratio between 1000 and 10 000, fabricated in two molar ratios of CH 4 -H 2 mixture (1 % and 4 %). Boron-doped diamond (BDD) film on the fused silica was presented as a conductive coating for optical and electronic purposes. The scanning electron microscopy images showed homogenous and polycrystalline surface...
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Influence of Laser Modification on the Surface Character of Biomaterials: Titanium and Its Alloys—A Review
PublikacjaLaser surface modification is a widely available and simple technique that can be applied to different types of materials. It has been shown that by using a laser heat source, reproducible surfaces can be obtained, which is particularly important when developing materials for medical applications. The laser modification of titanium and its alloys is advantageous due to the possibility of controlling selected parameters and properties...
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An observability and detectability analysis for non-linear uncertain CSTR model of biochemical processes
PublikacjaThe problem of proving observability/detectability properties for selected non-linear uncertain model of biochemical processes has been addressed in this paper. In particular, the analysis of observability/detectability in the face of parametric and unstructured uncertainty in system dynamics transformed into unknown inputs, and unknown initial conditions has been performed. Various sets of system measured outputs were taken into...
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Multiaxial Fatigue Behaviour of SLM 18Ni300 Steel
PublikacjaFatigue behaviour of SLM 18Ni300 steel under proportional bending-torsion loading is studied. The fatigue tests are conducted under pulsating loading conditions using tubular specimens with a transversal circular hole. Three ratios of the normal stress to shear stress are considered, namely σ/τ=4,σ/τ=2 and σ/τ = 4/3. Crack initiation sites were found for two diametrically opposite points around the hole, whose locations are governed...