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Search results for: bone tissue engineering
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Efficient knowledge-based optimization of expensive computational models using adaptive response correction
PublicationComputer simulation has become an indispensable tool in engineering design as they allow an accurate evaluation of the system performance. This is critical in order to carry out the design process in a reliable manner without costly prototyping and physical measurements. However, high-fidelity computer simulations are computationally expensive. This turns to be a fundamental bottleneck when it comes to design automation using numerical...
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Strategies for Dealing With Software Product Management Challenges
PublicationSoftware product management, which involves multiple processes and responsibilities and links to many activities within the organisation, increases the success rate of IT projects. However, the adoption of product management activities and the implementation of the software product manager role itself varies between companies. This research explores the topic of software product managers’ strategies for dealing with challenges...
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Katedra Inżynierii Drogowej. Zakład Budowy Dróg.
PublicationDepartment of Highway Engineering is divided into two divisions: Road Construction Division and Traffic Engineering Division. The head of Road Construction Division is Prof. J. Judycki. There are nine members of division: professor, three PhD, two MSc, two technicians and secretary. The main areas of research activities are: analysis of flexible, semi-rigid and rigid pavements, resistance of asphalt pavement to permanent deformation,...
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Modelling of spirometry - the application for diagnostic purposes
PublicationThe process of the tissue oxygen supply is the fundamental process of the human life. The lung functioning consists of three processes: the ventilation, the perfusion and the diffusion. The paper deals with one of these processes which is the ventilation process. The quality of the pulmonary ventilation has a strong influence on the patient's health condition. Numerous limitations are imposed on conditions of the lung quality measurement,...
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Model of optical phantoms thermal response upon irradiation with 975 nm dermatological laser
PublicationWe have developed a numerical model describing the optical and thermal behavior of optical tissue phantoms upon laser irradiation. According to our previous studies, the phantoms can be used as substitute of real skin from the optical, as well as thermal point of view. However, the thermal parameters are not entirely similar to those of real tissues thus there is a need to develop mathematical model, describing the thermal and...
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Special techniques and future perspectives: Simultaneous macro- and micro-electrode recordings
PublicationThere are many approaches to studying the inner workings of the brain and its highly interconnected circuits. One can look at the global activity in different brain structures using non-invasive technologies like positron emission tomography (PET) or functional magnetic resonance imaging (fMRI), which measure physiological changes, e.g. in the glucose uptake or blood flow. These can be very effectively used to localize active patches...
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Gold nanoparticles evaluation using functional optical coherence tomography
PublicationThe main object of this research was to assess the ability to characterize the gold nanoparticles using optical modalities like optical coherence tomography. Since the nanoparticles, especially gold one, have been very attractive for medical diagnosis and treatment the amount of research activities have been growing rapidly. The nanoparticles designed for different applications like contrast agents or drugs delivery change the...
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Mechanical behaviour of the implant used in human hernia repair under physiological loads
PublicationIn laparoscopic operations of abdominal hernias some recurrences still take place, even when applying a surgical mesh. This is usually caused by a failure of the connection between the tissue and the implant. The study deals with the influence of an implant’s orientation on forces in joints, which connect the mesh to human tissues. In the paper, the implant is modelled as a membrane structure within framework of the Finite Element...
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Treatment of Odontogenic Maxillary Sinusitis with the Use of Growth Factors in Advanced Platelet-Rich Fibrin for Immediate Closure of Oro-Antral Communication: A Case Report
PublicationChronic odontogenic maxillary sinusitis (COMS), a prolonged inflammation of the maxillary sinus lasting over 12 weeks, is often a result of periapical lesions, marginal periodontitis, and complications like oro-antral communication (OAC) and fistula (OAF). OAC, commonly emerging post-teeth extraction in the lateral maxilla, lacks documented treatments using advanced platelet-rich fibrin (A-PRF). This study evaluates A-PRF’s efficacy...
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Effect of double thermal and electrochemical oxidation on titanium alloys for medical applications
PublicationThe research focuses on the development and characterization of innovative thin hybrid oxide coatings obtained in subsequent processes of thermal (TO) and electrochemical (EO) oxidation. Four different surface modifications were investigated and the microstructure was determined, the mechanical, chemical and biological properties of the Ti-13Nb-13Zr alloy were assessed using scanning electron microscopy, X-ray dispersion analysis,...
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Relative quantification of pork and beef in meat products using global and species-specific peptide markers for the authentication of meat composition
PublicationWe used global and species-specific peptide markers for a relative quantitative determination of pork and beef in raw and processed meat products made of the two meat species. Four groups of products were prepared (i.e., minced raw meats, sausages, raw and fried burgers) in order to represent products with different extents of food processing. In each group, the products varied in the pork/beef proportions. All products were analysed...
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Powikłania po rekonstrukcji piersi: problem zakażeń i strategii prewencyjnej - przegląd literaturowy
PublicationW niniejszej pracy przedstawiono dane dotyczące powikłań po rekonstrukcji piersi. Manuskrypt ma na celu usystematyzowanie wyników badań z ostatnich lat wraz z aspektami, takimi jak: częstotliwość występowania powikłań oraz ich rodzaj, czynniki predysponujące, a także możliwości profilaktyki. Przeanalizowano dane literaturowe z ogólnie dostępnych artykułów z okresu ostatnich pięciu lat, ze szczególnym uwzględnieniem zakażeń. Do...
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Redukcja obciążeń odmorskich ścian falochronów pionowościennych przy zastosowaniu ścian ażurowych i komór wygaszających
PublicationPoszukiwanie optymalnych rozwiązań w projektowaniu falochronów portowo-morskich stanowi ciągłe wyzwanie dla projektantów w dziedzinie hydrotechniki portowo-morskiej. W przypadku falochronów morskich jednym z decydujących czynników mających wpływ na wybór rodzaju konstrukcji jest uzyskanie maksymalnej możliwej redukcji obciążeń od falowania morskiego. Niniejsza praca poświęcona jest rozwiązaniom konstrukcyjnym skrzyń żelbetowych,...
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Isolation of the relative decrease in magnetic permeability contribution to reluctance of an open magnetic circuit based on stray field measurements
PublicationThe goal of the study was to evaluate a relative decrease in magnetic permeability in open magnetic circuits based on stray magnetic field measurements. The boundary element method was used to simulate magnetic circuits with variable geometry and variable magnetic permeability. The simulated magnetic circuits were rectangular or bone-shaped flat samples. Reluctance was increased in the middle of the samples resulting in leakage...
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Comprehensive Evaluation of the Biological Properties of Surface-Modified Titanium Alloy Implants
PublicationAn increasing interest in the fabrication of implants made of titanium and its alloys results from their capacity to be integrated into the bone system. This integration is facilitated by different modifications of the implant surface. Here, we assessed the bioactivity of amorphous titania nanoporous and nanotubular coatings (TNTs), produced by electrochemical oxidation of Ti6Al4V orthopedic implants’ surface. The chemical composition...
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PARAMETERS OF THE ELECTROPHORETIC DEPOSITION PROCESS AND ITS INFLUENCE ON THE MORPHOLOGY OF HYDROXYAPATITE COATINGS. REVIEW
PublicationMetallic materials intended for bone implants should exhibit not only appropriate mechanical properties, but also high biocompatibility. The surface treatment modifications, for example acidic treatment, laser treatment, ion implantation and deposition of highly biocompatible coatings, are practiced. One of the most popular methods of surface modification is to deposit hydroxyapatite (HAp) coatings. HAp naturally occurs in human...
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The early failure of the gamma nail and the dynamic hip screw in femurs with a wide medullary canal. A biomechanical study of intertrochanteric fractures
PublicationBackground: Intertrochanteric fractures may occur in a bone with a wide medullary canal that may lead to significant mobility of a intramedullary nail, contrary to an extramedullary device. This study evaluates the Dynamic Hip Screw and the gamma nail in AO 31.A2.1 fractures in these circumstances. Methods: Synthetic femora with canals drilled to 18 mm were used. Five fixation types were examined: a 2 - hole and a 4 – hole Dynamic...
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Transcriptome profiling reveals distinctive traits of retinol metabolism and neonatal parallels in the MRL/MpJ mouse
PublicationBackground: The MRL/MpJ mouse is a laboratory inbred strain known for regenerative abilities which are manifested by scarless closure of ear pinna punch holes. Enhanced healing responses have been reported in other organs. A remarkable feature of the strain is that the adult MRL/MpJ mouse retains several embryonic biochemical characteristics, including increased expression of stem cell markers. Results: We explored the transcriptome...
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Higher platelet counts correlate to tumour progression and can be induced by intratumoural stroma in non-metastatic breast carcinomas
PublicationBackground Platelets support tumour progression. However, their prognostic significance and relation to circulating tumour cells (CTCs) in operable breast cancer (BrCa) are still scarcely known and, thus, merit further investigation. Methods Preoperative platelet counts (PCs) were compared with clinical data, CTCs, 65 serum cytokines and 770 immune-related transcripts obtained using the NanoString technology. Results High normal...
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Detecting type of hearing loss with different AI classification methods: a performance review
PublicationHearing is one of the most crucial senses for all humans. It allows people to hear and connect with the environment, the people they can meet and the knowledge they need to live their lives to the fullest. Hearing loss can have a detrimental impact on a person's quality of life in a variety of ways, ranging from fewer educational and job opportunities due to impaired communication to social withdrawal in severe situations. Early...
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MaliciousIDE – software development environment that evokes emotions
PublicationEmotions affect every aspect of human live, including work. Numerous studies in software engineering have shown that negative emotions can lower the productivity of programmers. Unlike traditional approaches to managing software development, modern methods, such as Agile and Lean, take into account human aspects of programming. To thoroughly investigate the impact of negative emotions on the work of programmers, a malicious integrated...
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Intelligent Autonomous Vehicles
PublicationAdvanced mobile vehicles and robots have long been one of the main issues in engineering. They have various applications in emergency, lifeguarding and entertainment as well as in various industrial, civil and military systems. Among them, you can distinguish robots that can move in an open environment or operate only in predetermined confined spaces. Open world robots are very demanding because they have...
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Environmental impact and industrial development of biorenewable resources for polyurethanes
PublicationPolyurethanes are among the most developed types of polymers. They are produced from the three primary components, i.e., polyols, low-molecular-weight glycols used as chain extenders, and diisocyanates. Until recently, all these substrates have been obtained via petrochemical processes. A decrease in petroleum-based resources and new ecological trends in chemistry, chemical technology, and materials engineering have generated increasing...
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Software Modeling from the Perspective of Intuitive Information Processing
PublicationThere is psychological evidence that humans process information not only consciously but also intuitively. Intuitive information processing is present also during the activities related to software modeling. The goal of this paper is to analyze software modeling from the perspective of theories which describe intuitive (nonconscious, implicit) information processing. The paper includes presentation of relevant psychological theories,...
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Educational Dataset of Handheld Doppler Blood Flow Recordings
PublicationVital signals registration plays a significant role in biomedical engineering and education process. Well acquired data allow future engineers to observe certain physical phenomena as well learn how to correctly process and interpret the data. This dataset was designed for students to learn about Doppler phenomena and to demonstrate correctly and incorrectly acquired signals as well as the basic methods of signal processing. This...
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The 12 principles of green analytical chemistry and the SIGNIFICANCE mnemonic of green analytical practices
PublicationThe current rapid development of green analytical chemistry (GAC) requires clear, concise guidelines in the form of GAC principles that will be helpful in greening laboratory practices. The existing principles of green chemistry and green engineering need revision for their use in GAC because they do not fully meet the needs of analytical chemistry. In this article we propose a set of 12 principles consisting of known concepts...
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Factors Affecting the Rheological Properties of Foods
PublicationIn this chapter, engineering aspects concerning real body mechanics and the impact of respective food ingredients on said properties are presented together. Food is a complex matrix and each of macro and micro ingredients plays its role in the formation of rheologic properties, and minor changes in the basic ingredient structure may affect the change of these properties significantly. Basic analytic techniques are presented for...
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Methods of deep modification of low-bearing soil for the foundation of new and spare air runways
PublicationAfter analyzing the impact of aircraft on the airport pavement (parking spaces, runways, startways), it was considered advisable to consider the problem of deep improvement or strengthening of its subsoil. This is especially true for low-bearing soil. The paper presents a quick and effective method of strengthening the subsoil intended for the construction of engineering structures used for civil...
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Inżynieria odwrotna bazy paliw płynnych w Gdańsku
PublicationArtykuł prezentuje prace z zakresu pozyskania danych o zbiornikach bazy paliw płynnych w Gdańsku. Przedstawione rozwiązanie nie ogranicza się tylko do stworzenia (rejestracji) chmury punktów, ale jest próbą wskazania użycia naziemnego skaningu laserowego do stworzenia bazy informacji o bazie paliw – w tym głównie geometrii zbiorników. Autorzy prezentują proces inwentaryzacji, rejestrację chmury punktów oraz wskazują zasady tworzenia...
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Na granicy wody i lądu – pojęcie niebieskiej przestrzeni urbanistycznej
PublicationObecnie obserwuje się wzrost zainteresowania projektowaniem urbanistycznym i architektonicznym z wykorzystaniem wody lub wręcz projektowania nowych terenów miejskich na obszarach wodnych. Sposób postrzegania strefy graniczenia wody i lądu w mieście ulega transformacji, a związek między tymi dwoma tkankami – znacznemu zacieśnieniu, w skutek czego w ostatnim dziesięcioleciu zaczęło kształtować się pojęcie niebieskich przestrzeni miejskich....
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New conjugates of tuftsin and muramyl dipeptide as stimulators of human monocytes-derived dendritic cells
PublicationMuramyl dipeptide (MDP) and tuftsin are known biologically active compound displaying a significant influence on various cell populations of innate immune response. MDP, as a fragment of bacterial cell wall, stimulates not only macrophages and monocytes, but also dendritic cells. In contrast, little is known about tuftsin influence on these cells. Therefore it seemed vital to access whether tuftsin or its derivatives conjugated...
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Progress in targeting tumor cells by using drug-magnetic nanoparticles conjugate.
PublicationTo limit the cytotoxicity of anticancer drugs against healthy cells, an appropriate carrier should be synthesized to deliver the drug to the tumor tissue only. A good solution is to anchor a magnetic nanoparticle to the molecule of the drug and to use a properly directed external magnetic field. We have shown that the improved by us synthesis of the conjugate of doxorubicin with iron-oxide magnetic nanoparticles allows a substantial...
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Sensitivity analysis based on non-intrusive regression-based polynomial chaos expansion for surgical mesh modelling
PublicationThe modelling of a system containing implants used in ventral hernia repair and human tissue suffers from many uncertainties. Thus, a probabilistic approach is needed. The goal of this study is to define an efficient numerical method to solve non-linear biomechanical models supporting the surgeon in decisions about ventral hernia repair. The model parameters are subject to substantial variability owing to, e.g., abdominal wall...
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Development of Safirinium dyes for new applications: fluorescent staining of bacteria, human kidney cells, and the horny layer of the epidermis
PublicationLow-molecular synthetic fluorophores are convenient tools in bioimaging applications. Several derivatives of Safirinium dyes as well as their reactive N-hydroxysuccinimide (NHS) esters bearing diverse substituents were synthesized and evaluated experimentally in terms of their lipophilicity by means of reverse-phase and immobilized artificial membrane high-performance liquid chromatography. Subsequently, the selected compounds...
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Layered Morphology of Gdansk: Past, Present and Future.
PublicationThis study aims to analyze the urban fabric and form of the city of Gdańsk based on the Muratorian and Italian school of urban morphology, to deepen the understanding of the morphological process of the urban fabric. It can be seen that the urban fabric of the city is a juxtaposition of all these layers, and based on Muratori’s approach these are indicative of not just the past, present but also the future. The study sample is...
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Pathogenesis of psoriasis in the “omic” era. Part III. Metabolic disorders, metabolomics, nutrigenomics in psoriasis
PublicationPsoriasis is a systemic disease that is strictly connected with metabolic disorders (insulin resistance, atherogenic dyslipidemia, arterial hypertension, and cardiovascular diseases). It occurs more often in patients with a more severe course of the disease. Obesity is specially an independent risk factor and it is associated with a worse treatment outcome because of the high inflammatory activity of visceral fatty tissue and...
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Performance Evaluation of Preemption Algorithms in MPLS Networks
PublicationPreemption is a traffic engineering technique in Multiprotocol Switching Networks that enables creation of high priority paths when there is not enough free bandwidth left on the route. Challenging part of any preemption method is to select the best set of paths for removal. Several heuristic methods are available but no wider comparison had been published before. In this paper, we discuss the dilemmas in implementing preemption...
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Semantic technologies based method of collection, processing and sharing information along food chain
PublicationIn the paper the method of collecting, processing and sharing information along food chain is presented. Innovative features of that method result from advantages of data engineering based on semantic technologies. The source to build ontology are standards and regulations related to food production, and data collected in databases owned by food chain participants. It allows food chain information resources can be represented in...
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Dynamics analysis of footbridge mode shapes the s8 expressway on the basis of the results of in situ tests
PublicationNon-destructive diagnostics for structure may use dynamic measurements realized during vibrations of a facility induced by dynamic environmental impact, enforced by the use of inductors or impulse impact. Dynamic tests and the analysis were undertaken for a footbridge situated over the expressway S8. The studies in situ allowed for dynamic characteristics to be determined: frequency, shape modes and damping for respective frequency...
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Investigations of Titanium Implants Covered with Hydroxyapatite Layer
PublicationTo reduce unfavorable phenomena occurring after introducing an implant into human body various modifications of the surface are suggested. Such modifications may have significant impact on biocompatibility of metallic materials. The titanium and it's alloys are commonly used for joint and dental implants due to their high endurance, low plasticity modulus, good corrosion resistance as well as biocompatibility. Special attention...
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S-Modules - An Approach to Capture Semantics fo Modularized DL Knowledge Bases
PublicationModularity of ontologies has been recently recognized as a key requirement for collaborative ontology engineering and distributed ontology reuse. Partitioning of an ontology into modules naturally gives rise to development of module processing methods. In this paper we describe an algebra of ontology modules developed during our work on a Knowledge Base Management System called RKaSeA. The idea differs from other algebras in the...
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Monitoring of underdeck corrosion by using acoustic emission method
PublicationThis paper presents first short characteristics of underdeck corrosion process as well as a problem of its monitoring. Next is described an acoustic emission (AE) method elaborated by Department of Ship Technology , Quality Systems and Material Engineering, Gdańsk University of Technology in cooperation with partners of CORFAT project realized within 7th EU Frame Program . Further are presented short characteristics of the emission...
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Application of gpr method in diagnostics of reinforced concrete structures
PublicationThis paper presents an application of the ground penetration method (GPR) for diagnostics of reinforced concrete structures. In situ measurements were conducted for three civil engineering structures: the ground floor structure, the abutment of the railway viaduct and the concrete well. The dual polarized ground penetrating radar with the antenna operating at a center frequency of 2 GHz was used for GPR surveys. Three different...
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Enthalpies of formation of rare earth niobates, RE3NbO7
PublicationHigh-temperature oxide melt solution calorimetry was used to investigate energetics of a series of rare earth niobates RE3NbO7. All of investigated compounds were found to be stable in enthalpy in respect to their oxides. The enthalpy of formation from oxides becomes more exothermic as the size of the RE cation increases, a trend seen previously in other RE compounds including pyrochlores, perovskites, and phosphates. For smaller...
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Underwater acoustic communication system using broadband signal with hyperbolically modulated frequency
PublicationThe implementation of reliable acoustic underwater communication in shallow waters is a scientific and engineering challenge, mainly due to the permanent occurrence of the multipath phenomenon. The article presents the concept of a transmission system using a broadband signal with hyperbolically modulated frequency (HFM) to transmit data symbols and synchronize data frames. The simulation tests were carried out in channels with...
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Road Restraint Systems as a Basis for Roadside Safety Improvement
PublicationRoadside-related crashes occur when vehicles run off the road. The majority of the crashes have severe outcomes, especially when an object is hit (tree, pole, supports, front wall of a culvert, barrier). These accidents represent app. 19% of all of Poland's road deaths. Roadside crashes involve: hitting a tree, hitting a barrier, hitting a sign or utility pole, vehicle roll-over on the roadside, vehicle roll-over on a slope and...
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Stormwater runoff in the urbanized coastal basin of Gdańsk Urbanized basin of Gdańsk
PublicationAnthropopressure strongly affects the primal water cycle. Alternation of the natural basins imposes changes of drainage patterns, reduction of bioretention, infiltration and base flow. As a result the overland flow predominates and greater runoff rates flow into storm water collection systems and reservoirs. Moreover changing climatic conditions increase the frequency of rapid extreme weather events. Infrastructures of urban areas...
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Application of foam made of post-consumer pet materials for the construction of footbridges
PublicationThe article presents the possibility of application in civil engineering of highly ecological PET foam, manufactured from 100% recycled plastic packaging. It may find uses in construction of numerous engineering structures, such as pedestrian and cycle footbridges. Properly processed waste from post-consumer PET packaging may constitute a quality structural core for use in multilayered composite materials, commonly referred to...
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Design Methodology for Small Passenger Ships On the Example of the Ferryboat Motława 2 Driven by Hybrid Propulsion System
PublicationDynamic development in practically all elds of science and engineering has not passed over shipbuilding . In last years , engineers got to their use computer soware which makes it possible to perform strength and hydrodynamic calculations as well as to visualize design projects in 3 D space [1-4]. At their disposal they have full spectrum of modern solutions associated with the use of advanced materials and technologies [5-7]....
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Automated Reasoning Based User Interface
PublicationMotivation: The ability to directly trace how requirements are implemented in a software system is crucial in domains that require a high level of trust (e.g. medicine, law, crisis management). This paper describes an approach that allows a high level of traceability to be achieved with model-driven engineering supported by automated reasoning. The paper gives an introduction to the novel, automated user interface synthesis in...