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Personalized avatar animation for virtual reality
PublicationThe paper presents a method for creating a personalized animation of avatar for virtual reality application such as multiplayer on-line games. Animation is stored in a simplified version, containing only keyframes for important avatar poses. This version defines key movements, i.e. roughly describes the avatar's action. Animation is enriched by the user with new motion phases utilizing fuzzy descriptors.Various degrees of motion...
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A Comparative Study of Fuzzy SMC with Adaptive Fuzzy PID for Sensorless Speed Control of Six-Phase Induction Motor
PublicationMulti-phase motors have recently replaced three-phase induction motors in a variety of applications due to the numerous benefits they provide, and the absence of speed sensors promotes induction motors with variable speed drives. Sensorless speed control minimizes unnecessary speed encoder cost, reduces maintenance, and improves the motor drive’s reliability. The performance comparison of the fuzzy sliding mode controller (FSMC)...
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Future of nature, our future. A preregistered report on future time perspective, social value orientation, and pro-environmental outcomes based on data from Poland and Sweden
PublicationIntroduction: The objective of the study was to examine the role of social value orientation and future time perspective to account for individual differences in pro-environmental behaviors, intentions, and opinions about the link between pro-environmental action and pandemic threat (three separate models) in Polish and Swedish samples expected to differ in rate of pro-environmental behaviors (higher in Sweden). We hypothesized...
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Sustainable chemically modified poly(butylene adipate-co-terephthalate)/thermoplastic starch/poly(ε-caprolactone)/cellulose biocomposites: looking at the bulk through the surface
PublicationSustainable polymer composites (or biocomposites) based on renewable and green polymers are progressively under development in a technological paradigm shift from “just use more and more” to “convert into value-added products”. Therefore, significant efforts should focus not only on their reduced environmental impact but also on maximizing their performance and broadening their application range. Herein, the bio-based blends based...
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Beyond Antioxidant Activity: Redox Properties of Catechins May Affect Changes in the DNA Methylation Profile—The Example of SRXN1 Gene
PublicationThe role of catechins in the epigenetic regulation of gene expression has been widely studied; however, if and how this phenomenon relates to the redox properties of these polyphenols remains unknown. Our earlier study demonstrated that exposure of the human colon adenocarcinoma HT29 cell line to these antioxidants affects the expression of redox-related genes. In particular, treatment with (−)-epigallocatechin (EGC) downregulated...
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Hydrochar-nanoparticle integration for arsenic removal from wastewater: Challenges, possible solutions, and future horizon
PublicationArsenic (As) contamination poses a significant threat to human health, ecosystems, and agriculture, with levels ranging from 12 to 75% attributed to mine waste and stream sediments. This naturally element is abundant in Earth's crust and gets released into the environment through mining and rock processing, causing ≈363 million people to depend on As-contaminated groundwater. To combat this issue, introducing a sustainable hydrochar...
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Highly Conserved Homotrimer Cavity Formed by the SARS-CoV-2 Spike Glycoprotein: A Novel Binding Site
PublicationAn important stage in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) life cycle is the binding of the spike (S) protein to the angiotensin converting enzyme-2 (ACE2) host cell receptor. Therefore, to explore conserved features in spike protein dynamics and to identify potentially novel regions for drugging, we measured spike protein variability derived from 791 viral genomes and studied its properties by molecular...
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An advanced tool integrating failure and sensitivity analysis into novel modeling of the stormwater flood volume
PublicationAn innovative tool for modeling the specific flood volume was presented that can be applied to assess the need for stormwater network modernization as well as for advanced flood risk assessment. Field measurements for a catchment area in Kielce, Poland, were used to apply the model and demonstrate its usefulness. This model extends the capability of recently developed statistical and machine learning hydrodynamic models developed...
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Analysis of the Water Level Variation in the Polish Part of the Vistula Lagoon (Baltic Sea) and Estimation of Water Inflow and Outflow Transport through the Strait of Baltiysk in the Years 2008–2017
PublicationThe Vistula Lagoon is located in both Poland and Russia along the southern coast of the Baltic Sea. It is connected to the Baltic Sea in the Russian part by the Strait of Baltiysk. The purpose of the paper is to identify the dominant factors underlying the water level variation mechanism at Tolkmicko in the Vistula Lagoon, revealed by a statistical analysis of the measured data and a discussion on the inflow and outflow transport...
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LED Light Sources and Their Complex Set-Up for Visually and Biologically Effective Illumination for Ornamental Indoor Plants
PublicationOrnamental plants are often used in indoor environments as part of biophilic design to improve the health and wellbeing of occupants, and to support sustainable, green architecture. Unfortunately, many plants do not thrive and need to be continuously replaced, which is economically unsustainable. The wavelengths and spectrum ratio of commonly used light sources such as light emitting diode (LED), and the lack of an appropriate...
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Design of Jack-up Platform for 6 MW Wind Turbine: Parametric Analysis Based Dimensioning of Platform Legs
PublicationThe article presents the results of the research conducted within the framework of the project entitled WIND-TU-PLA (ERA-NET, MARTEC II), the general aim of which was to design and analyse supporting structures for wind turbines intended for operation on the South Baltic area. The research part described in the article aimed at developing a preliminary design for a jack-up platform which can operate on water areas with depth of...
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Analysis of diagnostic informativeness of the exhaust temperature of a naval gas turbine
PublicationThe conducted investigations aimed to carry out an analysis of the possibility that the failures identification in the automatic control system of a gas turbine engine could be worked out on the basis of measurements of the exhaust stream temperature behind the gas generator. The exhaust temperature represents a basic control parameter, enabling technical state evaluation of the engine within the operation process, which is observed...
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Honey antibacterial activity: A neglected aspect of honey quality assurance as functional food
PublicationBackground Honey is considered as a functional food with health-promoting properties. Its potent antibacterial and antibiofilm effects are the major attributes of so called ‘medical-grade honey’ which is topically used for the treatment of burns, wounds and skin disorders. Nevertheless, the current set of honey quality parameters adopted in the European Union do not include its biological properties. Furthermore, in light of the...
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Management of Urban Waters with Nature-Based Solutions in Circular Cities—Exemplified through Seven Urban Circularity Challenges
PublicationNature-Based Solutions (NBS) have been proven to effectively mitigate and solve resource depletion and climate-related challenges in urban areas. The COST (Cooperation in Science and Technology) Action CA17133 entitled “Implementing nature-based solutions (NBS) for building a resourceful circular city” has established seven urban circularity challenges (UCC) that can be addressed effectively with NBS. This paper presents the outcomes...
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Towards a method for detecting large roll motions suitable for oceangoing ships
PublicationThe concept of autonomous merchant ships is quite recent. The increasing interest in autonomous vessels is nowadays calling for smart technologies that are supposed to replace the human actions on board. This involves troublesome issues related to ship safety. In the future, decision-making processes that are conventionally performed by human beings on board ship will be moved ashore to the control centre and maybe even completely...
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Generalized regression neural network and fitness dependent optimization: Application to energy harvesting of centralized TEG systems
PublicationThe thermoelectric generator (TEG) system has attracted extensive attention because of its applications in centralized solar heat utilization and recoverable heat energy. The operating efficiency of the TEG system is highly affected by operating conditions. In a series-parallel structure, due to diverse temperature differences, the TEG modules show non-linear performance. Due to the non-uniform temperature distribution (NUTD) condition,...
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The Distribution of Glucosinolates in Different Phenotypes of Lepidium peruvianum and Their Role as Acetyl- and Butyrylcholinesterase Inhibitors—In Silico and In Vitro Studies
PublicationThe aim of the study was to present the fingerprint of different Lepidium peruvianum tu- ber extracts showing glucosinolates-containing substances possibly playing an important role in preventinting dementia and other memory disorders. Different phenotypes of Lepidium peruvianum (Brassicaceae) tubers were analysed for their glucosinolate profile using a liquid chromatograph coupled with mass spectrometer (HPLC-ESI-QTOF-MS/MS platform)....
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New 2-[(4-Amino-6-N-substituted-1,3,5-triazin-2-yl)methylthio]-N-(imidazolidin-2-ylidene)-4-chloro-5-methylbenzenesulfonamide Derivatives, Design, Synthesis and Anticancer Evaluation
PublicationIn the search for new compounds with antitumor activity, new potential anticancer agents were designed as molecular hybrids containing the structures of a triazine ring and a sulfonamide fragment. Applying the synthesis in solution, a base of new sulfonamide derivatives 20–162 was obtained by the reaction of the corresponding esters 11–19 with appropriate biguanide hydrochlorides. The structures of the compounds were confirmed...
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A Comparative Study of Fuzzy SMC with Adaptive Fuzzy PID for Sensorless Speed Control of Six-Phase Induction Motor
PublicationMulti-phase motors have recently replaced three-phase induction motors in a variety of applications due to the numerous benefits they provide, and the absence of speed sensors promotes induction motors with variable speed drives. Sensorless speed control minimizes unnecessary speed encoder cost, reduces maintenance, and improves the motor drive’s reliability. The performance comparison of the fuzzy sliding mode controller (FSMC)...
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Assessing ecotoxicity and the endocrine potential of selected phthalates, BADGE and BFDGE derivatives in relation to environmentally detectable levels
PublicationThere is no doubt that the subject area of plasticmaterials (e.g., production of epoxy resins or polyesters) is inherently connected to issues concerning bisphenol A (BPA) and its analogues. Unfortunately, much less attention has been given to other compounds, which are also used for the production of these materials. Bisphenol A diglycidyl ether (BADGE) is a synthetic industrial compound obtained by a condensation reaction between...
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Settlement Networks in Polish Spatial Development Regional Plans
PublicationIn 1999, ten years after the great political changes in Poland, 16 self-governed regions (in Polish: voivodeship) were created. According to Polish law, voivodeship spatial development plans, or regional plans in short, determine basic elements of the settlement network. No detailed regulations indicate the specific elements of the settlement network or what features of these elements should be determined. For this reason, centres...
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Combined Single Neuron Unit Activity and Local Field Potential Oscillations in a Human Visual Recognition Memory Task
PublicationGOAL: Activities of neuronal networks range from action potential firing of individual neurons, coordinated oscillations of local neuronal assemblies, and distributed neural populations. Here, we describe recordings using hybrid electrodes, containing both micro- and clinical macroelectrodes, to simultaneously sample both large-scale network oscillations and single neuron spiking activity in the medial temporal lobe structures...
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Molecular basis for the DNA damage induction and anticancer activity of asymmetrically substituted anthrapyridazone PDZ-7
Publicationnthrapyridazones, imino analogues of anthraquinone, constitute a family of compounds with remarkable anti-cancer activity. To date, over 20 derivatives were studied, of which most displayed nanomolar cytotoxicity towards broad spectrum of cancer cells, including breast, prostate and leukemic ones. BS-154, the most potent derivative, had IC50 values close to 1 nM, however, it was toxic in animal studies. Here, we characterize another...
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Modulation of UDP-glucuronidation by acridinone antitumor agents C-1305 and C-1311 in HepG2 and HT29 cell lines, despite slight impact in noncellular systems.
PublicationBackground Among the studied antitumor acridinone derivatives developed in our laboratory, 5-dimethylaminopropylamino-8-hydroxytriazoloacridinone (C-1305) and 5-diethylaminoethylamino-8-hydroxyimidazoacridinone (C-1311) exhibited cytotoxic and antitumor properties against several cancer types and were selected to be evaluated in preclinical and early-phase clinical trials. In the present work, we investigated the impact of C-1305...
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MODELOWANIE WYBRANYCH MIAR BEZPIECZEŃSTWA RUCHU NA DŁUGICH ODCINKACH DRÓG
PublicationKażdego roku w wypadkach drogowych na świecie życie traci prawie 1,3 mln osób, co oznacza prawie niemal 3 tys. ofiar dziennie,. Tyle samo zabitych w ruchu drogowym odnotowujemy rocznie w Polsce. Ekonomiczne straty w wyniku tych wypadków wynoszą ok. 2% światowego PKB. W roku 2010 Organizacja Narodów Zjednoczonych (ONZ) przyjęła rezolucję pt. „Dekada działań na rzecz bezpieczeństwa ruchu drogowego na lata 2011 – 2020” rozpoczynającą...
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Warstwowa ocena epidemiologiczna architektury zakładów opiekuńczo-leczniczych i zakładów gieriatycznych = Layer based epidemiological quality assessment of architecture of care security and geriatric wards
PublicationW artykule opisano możliwość wykorzystania autorskiej metody warstwowej oceny epidemiologicznej (WOE) do oceny potencjalnego ryzyka zakażeń w obiektach przeznaczonych dla osób starszych. Materiał i metody: W celu weryfikacji możliwości użycia metody WOE do oceny zagrożeń w zakresie bezpieczeństwa epidemiologicznego środowiska zbudowanego poddano analizie dostępne źródła literatury związane z obowiązującymi w Polsce wymaganiami...
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New method for personalization of avatar animation
PublicationThe paper presents a method for creating a personalized animation of avatar utilizing fuzzy inference. First the user designs a prototype version of animation, with keyframes only for important poses, roughly describing the action. Then animation is enriched with new motion phases calculated by the fuzzy inference system using descriptors given by the user. Various degrees of motion fluency and naturalness are possible to achieve....
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Structural studies of a cold-adapted dimeric Beta-D-galactosidase from Paracoccus sp. 32d
PublicationThe crystal structure of a novel dimeric [beta]-D-galactosidase from Paracoccus sp. 32d (Par[beta]DG) was solved in space group P212121 at a resolution of 2.4 Å by molecular replacement with multiple models using the BALBES software. This enzyme belongs to glycoside hydrolase family 2 (GH2), similar to the tetrameric and hexameric [beta]-D-galactosidases from Escherichia coli and Arthrobacter sp. C2-2, respectively. It is the second...
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The Future of the University? Social Activism among Young Polish Scholars
PublicationThe question “Quo vadis, Academia?” is posed by scholars, research administrators, journalists and is also ofound in public opinion in Poland in different contexts. Authors of the article do not call into question the necessity of changes of contemporary universities, but they think that the source of changes should be characterized by a bottom-up approach, especially by those who have already achieved extraordinary scientific...
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The method of analysis of damage reinforced concrete beams using terrestial laser scanning
PublicationThe authors present an analysis of the possibility to assess deformations and mechanisms of destructing bent reinforced concrete beams using the terrestrial laser scanning. As part of the experiments carried out at the Regional Laboratory of Construction of the Concrete Structures Division of the Civil and Environmental Engineering Faculty at Gdansk University of Technology, the reinforced concrete beams were subjected to destruction...
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Decoding imagined speech for EEG-based BCI
PublicationBrain–computer interfaces (BCIs) are systems that transform the brain's electrical activity into commands to control a device. To create a BCI, it is necessary to establish the relationship between a certain stimulus, internal or external, and the brain activity it provokes. A common approach in BCIs is motor imagery, which involves imagining limb movement. Unfortunately, this approach allows few commands. As an alternative, this...
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A new 1-nitro-9-aminoacridine derivative targeting yeast topoisomerase II able to overcome fluconazole-resistance
PublicationFungal resistance remains a significant threat and a leading cause of death worldwide. Thus, overcoming microbial infections have again become a serious clinical problem. Although acridine derivatives are widely analyzed as anticancer agents, only a few reports have demonstrated their antifungal activity. In an effort to develop biologically active antifungals, twelve novel C-857 (9-(2′ -hydroxyethylamino)-1-nitroacridine) and...
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Systematic review examining the evidence for impact of school policies on physical activity
PublicationBackground Epidemiological evidence has demonstrated that physical activity can have substantive health benefits for children and young people. The 'Policy Evaluation Network' is a multi-disciplinary research network across 7 European countries and New Zealand aimed at building capacity and evaluating the level of impact of policy interventions for promoting healthy lifestyles. The Toronto Charter identified 'whole-of-school' programmes...
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Mono- and bimetallic (Pt/Cu) titanium(IV) oxide core–shell photocatalysts with UV/Vis light activity and magnetic separability
PublicationTitanium(IV) oxide is one of the most widely investigated photocatalysts. However, separation of nano-sized particulate titania might result in profitless technologies for commercial applications. Additionally, bare titania is almost inactive under the Vis range of solar spectrum due to its wide bandgap. Therefore, the present study aims to prepare novel coreinterlayer- shell TiO2 magnetic photocatalysts modified with metal nanoparticles...
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‘The Urban Walk Architecture Talk’— Bridging Socially Engaged Art, Urban Processes and Cultural Development
Publication“Urban Walk—Architecture Talk” is a project based on an elective seminar under the same title organized at the Faculty of Architecture of Gdańsk University of Technology. It aims at getting familiar with the topic of multi-layer and multi-sensory reception of public space, mainly by recognizing the needs of its users. Additionally, it deals with the consequences of such perception and the use of space in order to build more complete...
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Electrochemical simulation of metabolic reduction and conjugation reactions of unsymmetrical bisacridine antitumor agents, C-2028 and C-2053
PublicationElectrochemistry (EC) coupled with analysis techniques such as liquid chromatography (LC) and mass spectrometry (MS) has been developed as a powerful tool for drug metabolism simulation. The application of EC in metabolic studies is particularly favourable due to the low matrix contribution compared to in vitro or in vivo biological models. In this paper, the EC(/LC)/MS system was applied to simulate phase I metabolism of the representative...
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Lipopolysaccharides: regulated biosynthesis and structural diversity
PublicationThe cell envelope of Gram-negative bacteria contains two distinct membranes, an inner (IM) and an outer (OM) membrane, separated by the periplasm, a hydrophilic compartment that includes a thin layer of peptidoglycan. The most distinguishing feature of such bacteria is the presence of an asymmetric OM with phospholipids located in the inner leaflet and lipopolysaccharides (LPSs) facing the outer leaflet. The maintenance of this...
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Highly efficient maximum power point tracking control technique for PV system under dynamic operating conditions
PublicationThe application of small-scale electrical systems is widespread and the integration of Maximum Power Point Tracking (MPPT) control for Photovoltaic systems with battery applications further enhances the techno-economic feasibility of renewable systems. For this purpose, a novel MPPT control system using Dynamic Group based cooperation optimization (DGBCO) algorithm is utilized for PV systems. The population in the DGBCO is divided...
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Dibutyl phthalate disrupts conserved circadian rhythm in Drosophila and human cells
PublicationPeople are constantly exposed to phthalates, due to their common use in the production of plastics, pharmaceuticals, cosmetics and skin care products. The ability of phthalates to disrupt endocrine signaling, leading to developmental, reproductive and metabolic defects, has been studied, yet how phthalates interfere with these biological functions is still unclear. To uncover DBP interacting molecular pathways, we raised Drosophila...
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Technological solutions to landfill management: Towards recovery of biomethane and carbon neutrality
PublicationInadequate landfill management poses risks to the environment and human health, necessitating action. Poorly designed and operated landfills release harmful gases, contaminate water, and deplete resources. Aligning landfill management with the Sustainable Development Goals (SDGs) reveals its crucial role in achieving various targets. Urgent transformation of landfill practices is necessary to address challenges like climate change,...
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Architects and urban planners in the face of energy transition - smart cities energy aspects in shaping building structures and cities
PublicationContemporary architects and urban planners are facing steadily increasing challenges. The growing problems around environmental issues, shrinking natural resources and climate action are just some of them. Currently, planning should also include balancing with all the aspects of sustainable development such as not only the environmental issues, but also social and economic ones. How to meet them in the era of energy transition...
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Analysis of the causes and effects of cyclist-pedestrian accidents in biggest Polish cities
PublicationTraffic incidents between pedestrians and cyclists result in an incomparably smaller number of victims (injured and killed) than accidents between unprotected traffic participants and other vehicles. However, such incidents cannot be underestimated, as in most cases they take place on elements of infrastructure designed for pedestrians and cyclists, and thus negatively affect the sense of safety of users in places where they...
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The Contemporary aspects of revitalization of the buildings and the port areas
PublicationPort cities are the forefront of globalization. The continued growth of international trade of goods and services has now played a major role in shaping the economic and social world. Strategies for mutual cooperation and follow-up between countries, cities and regions are increasingly complex. On the one hand it brings profits, on the other leads to destabilization and the need for transformation and constant modernization. Port...
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Prediction of Overall In Vitro Microsomal Stability of Drug Candidates Based on Molecular Modeling and Support Vector Machines. Case Study of Novel Arylpiperazines Derivatives
PublicationOther than efficacy of interaction with the molecular target, metabolic stability is the primary factor responsible for the failure or success of a compound in the drug development pipeline. The ideal drug candidate should be stable enough to reach its therapeutic site of action. Despite many recent excellent achievements in the field of computational methods supporting drug metabolism studies, a well-recognized procedure to model...
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Impact response of two-layered grouted aggregate fibrous concretecomposite under falling mass impact
PublicationTwo-layered Grouted Aggregates Fibrous Concrete Composite (TGAFCC) is a new category concrete which became popular recently and attracted the attention of researchers globally. Recent studies indicated that TGAFCC has notable improvement in mechanical properties, which has been sufficiently documented. However, the impact behaviour of TGAFCC when combined with Glass Fibre Mesh (GFM) and Textile Fibre Mesh (TFM) is still unexplored....
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Glucosinolates from lepidium peruvianum as potential antiamnestic drugs
PublicationLepidium peruvianum (maca) (Brassicaceae) is a naturally occurring plant mainly in the high Andes of Peru. In recent years, it has been intensively researched in terms of its influence on various diseases and towards health improvement. Alzheimer’s disease is an incurable disease that most often affects adults over the age of 60. As since 2003 the US Food and Drug Administration (FDA) did not approve any new drug for Alzheimer’s...
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Regenarative tourism – between theory and practice
PublicationPurpose: The aim of this article is to present a shift in thinking in terms of implementing the systems and practices needed to transition to a regenerative approach in tourism. The article aims to provide concrete ways to change thinking and move towards a regenerative paradigm in the tourism industry. Design/methodology/approach: This viewpoint paper defines regenerative tourism and explores its principles and the possibilities...
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Anticancer imidazoacridinone C-1311 inhibits hypoxia-inducible factor-1α (HIF-1α), vascular endothelial growth factor (VEGF) and angiogenesis
PublicationAntitumor imidazoacridinone C-1311 is a DNA-reactive topoisomerase II and FLT3 receptor tyrosine kinase inhibitor. Here, we demonstrate the mechanism of C-1311 inhibitory action on novel targets: hypoxia-inducible factor-1α (HIF-1α), vascular-endothelial growth factor (VEGF), and angiogenesis. In a cell-free system, C-1311 prevented HIF-1α binding to an oligonucleotide encompassing a canonical hypoxia-responsive element (HRE),...
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Systemic analysis of a manufacturing process based on a small scale bakery
PublicationThe main aim of the article is to present two new innovative concepts of reliability of a functioning manufacturing system in the process of making bread in small-scale bakeries. Reliability is understood as one of the representations of an operator acting on specifc streams in time to - t. One of these represents the global reliability of a system as a function of parallel action of all the streams of the system in time to to...
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Cold recycled mixtures for binder courses - laboratory evaluation of mechanical properties
PublicationCold recycled mixtures composed with cement and bituminous emulsion are nowadays commonly used material for base layer. Typical pavement with cold recycled mixtures usually consists of two asphalt courses (wearing and binding course) constructed over cold recycled base. Therefore the next step in cold recycling is possibility of design of binding courses with recycled materials, but with potential to obtain high quality mixtures...