Search results for: LINKED%20DATA%20ASSESSMENT
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An application supporting the educational process of the respiratory system obstructive diseases detection
PublicationThe paper presents a description of functioning of a platform supporting the detection of obstructive diseases in the respiratory system education process. A 16-parameter model of the respiratory system simulated in the MATLAB/Simulink environment was set in the role of the tested patient. It has been linked to the control layer, developed in the LabVIEW environment, using the SIT library (Simulation Interface Toolkit). This layer...
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Molecular Umbrellas Modulate the Selective Toxicity of Polyene Macrolide Antifungals
PublicationAntifungal polyene macrolide antibiotics Amphotericin B (AmB) and Nystatin (NYS) were conjugated through the ω-amino acid linkers with diwalled “molecular umbrellas” composed of spermidine-linked deoxycholic or cholic acids. The presence of “umbrella” substituents modulated biological properties of the antibiotics, especially their selective toxicity. Some of the AmB-umbrella conjugates demonstrated antifungal in vitro activity...
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New Peptide Based Fluconazole Conjugates with Expanded Molecular Targets
PublicationInfections of Candida spp. etiology are frequently treated with azole drugs. Among azoles, the most widely used in the clinical scenario remains fluconazole (FLC). Promising results in treatment of dangerous, systemic Candida infections demonstrate the advantages of combined therapies carried out with combinations of at least two different antifungal agents. Here, we report five conjugates composed of covalently linked FLC and...
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Comparison of Renewable Energy Sources in ‘New’ EU Member States in the Context of National Energy Transformations
PublicationThe European Union strives to create sustainable, low-carbon economies; therefore, energy policies of all member states should move towards renewable energy sources (RES). That concerns also the so-called new EU member states. These countries, on the one hand, are characterized by significant historical similarities in terms of post-communist legacy and adopted development strategies linked with the EU membership, and on the other...
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Enzymatic cross-linking of β-lactoglobulin in solution and at air–water interface: Structural constraints
PublicationEffective and controlled use of cross-linking enzymes in structure engineering of food systems depends on characterization of the favorable conditions for enzyme-substrate complex and the limiting factors for the desired modification. In this respect, we analyzed the susceptibility of bovine β-lactoglobulin (BLG) to enzymatic cross-linking by Trichoderma reesei tyrosinase (TrTyr) and transglutaminase (TG). Changes in BLG molecular...
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The image of the City on social media: A comparative study using “Big Data” and “Small Data” methods in the Tri-City Region in Poland
Publication“The Image of the City” by Kevin Lynch is a landmark planning theory of lasting influence; its scientific rigor and relevance in the digital age were in dispute. The rise of social media and other digital technologies offers new opportunities to study the perception of urban environments. Questions remain as to whether social media analytics can provide a reliable measure of perceived city images? If yes, what implication does...
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PCR-ELISA: inexpensive alternative to quantitative PCR
PublicationPCR-ELISA (polymerase chain reaction-enzyme linked immunosorbent assay), a combination of PCR and ELISA methods, has been used since late 1980s. The technique is based on specially labelled DNA fragments which are captured by specific DNA sequences and detected by antibodies. The whole procedure of PCR-ELISA is divided into three steps: DNA extraction, PCR reaction and detection by ELISA. The method has been found as very specific...
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Dynamic Semantic Visual Information Management
PublicationDominant Internet search engines use keywords and therefore are not suited for exploration of new domains of knowledge, when the user does not know specific vocabulary. Browsing through articles in a large encyclopedia, each presenting a small fragment of knowledge, it is hard to map the whole domain, see relevant concepts and their relations. In Wikipedia for example some highly relevant articles are not linked with each other....
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The Use of Photographs in the Teaching/Learning of Descriptive Geometry
PublicationThe article presents the concept of enriching the Descriptive Geometry course with photographs and several simplified real-life engineering tasks. The photographic images used for the exercises are tightly linked to engineering structures, the given specialization and the surrounding world. The photo image as a record of central projection of a real space can be useful for presentation and analysis of the properties of perspective....
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The Belt and Road Initiative and export variety: 1996–2019
PublicationThis study examines the association between the Belt and Road Initiative (BRI) and export variety (EV). We propose three hypotheses on how BRI may foster export markets (destinations) or export product lines. The estimates are based on a dataset constructed specifically for this analysis, covering 183 countries and linked with trade data from 1996 to 2019. We apply the instrumental variable (IV) approach in regressions for covering the...
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The “autumn effect” in the gold market—does it contradict the Adaptive Market Hypothesis?
PublicationThe present study aims to verify the autumn effect in the gold market, first presented 10 years ago by Dirk Baur in the paper “The autumn effect of gold” and to investigate the calendar effects occurring for other precious metals. This empirical research is presented in a way to place the results obtained in the context of the Efficient Market Hypothesis (EMH) and the more current Adaptive Market Hypothesis (AMH). The study was...
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Interline power flow controller - properties and control strategy in dynamic states
PublicationHigh-power electronic converter topologies, in such forms as Unified Power Flow Controllers (UPFC), Static Compensators (STATCOM) and Interline Power Flow Controllers (IPFC), have been used to enhance and optimize the use of transmission facilities, under the concept of a flexible ac transmission system (FACTS). In Europe, the anticipated proliferation of distributed-generation (DG) in the near future, driven by governmental initiatives...
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Chromogenic azomacrocycles with imidazole residue: Structure vs. properties
PublicationNew diazo macrocycles linked by hydrocarbon chain bearing imidazole or 4-methylimidazole residue have been synthetized with satisfactory yield (24–55%). The structure of macrocycles was confirmed by X-ray analysis and spectroscopic methods (1H NMR, MS, FTIR). Metal cation complexation studies were carried out in acetonitrile and acetonitrile-water system. It was found that azomacrocyles form triple-decker complexes with lead(II)....
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Cloning, expression, purification and characterization of recombinant trehalose synthase from Deinococcus radiodurans.
PublicationTrehalose (α-D-glucopyranosyl-1,1-α-D-glucopyranoside) is a nonreducing disacharide in which the two glucose molecules are linked trough a α-1,1-glycosidic bond. Trehalose is readily hydrolyzed to glucose and can be used as a reserve of that sugar in the cell. The presence of trehalose was found in the cells of fungi and yeasts, bacteria, nematodes, insects, eggs, pupae and some plants. The characteristics of trehalose make it...
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“Don’t call it work”: An interpretative phenomenological analysis of volunteer firefighting in young adults based on the volunteer process model
PublicationThe number of people engaging in volunteer firefighting is on the decline. It is important to understand what factors on a personal and social level and from the three stages of the volunteer process model: antecedents, experiences and consequences, might be linked to starting and sustaining such engagement. To address this problem, a qualitative, interview-based study was performed on a sample of 10 volunteer firefighters from...
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Determination of terpene profiles in potential superfruits
PublicationThe aim of this work was to characterize and compare the profiles of volatile terpenes in four potential superfruits. These profiles were determined using headspace solid-phase microextraction coupled with comprehensive two-dimensional gas chromatography linked to time-of-flight mass spectrometry. The proposed technique allowed the separation and identification of 79 terpenes present in cape gooseberry, crabapple, cherry silver...
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The Impact of Ergonomic Guiding Principles on the Formation of Modern Monumental Art
PublicationCommemoration of historic events is now a commonplace phenomenon both in culture and in academic research. The phenomenon is linked to an increase in the representation of the visualisation of the past in public sphere, which in turn leads to reformulation of monumental art. Modern monuments are often spatial forms consisting both of sculpture installation and bigger constructions. In case of these realisations, the designers,...
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Social perception of technological innovations at sports facilities: justification for financing ‘white elephants’ from public sources? The case of Euro 2012 Stadiums in Poland
PublicationThe main purpose of the paper is to provide a monetary valuation of social benefits in connection with the hypothetical implementation of technological innovations at four Euro 2012 stadiums in Poland. Not only the construction of the sport’s arenas, but also the ongoing maintenance drain the pockets of Polish taxpayers. At the same time Euro 2012 stadiums remain underused, which familiarize the host cities with the concept of ‘white...
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Molecular differences in mitochondrial DNA (mtDNA) genomes of dogs with malignant mammary tumours
Open Research DataThe aim of this study was to determine molecular defects in mitochondrial DNA with the use of large-scale genome analysis in malignant canine mammary gland tumours and indicate whether these changes were linked with the carcinogenesis process. With the use of the NGS technology, we sequenced 27 samples of mtDNA isolated from blood and tumours obtained...
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Precipitation of calcium carbonate in the presence of rhamnolipids in alginate hydrogels as a model of biomineralization
PublicationThis paper reports the effects of rhamnolipids presence in the alginate hydrogel and CO32- solution, on the precipitation of CaCO3 in the Ca2+ loaded alginate hydrogel. Characteristics of the formed particles are discussed. Model conditions containing alginate hydrogel and rhamnolipids were used in order to mimic the natural environment of biomineralization in biofilms. It has been shown that rhamnolipids affect the characteristics...
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Selective detection of F- by chromogenic tetrazole receptor
PublicationA chromogenic anion host 4, containing two amide functionalities linked to azo dye and tetrazole rings was synthesized and its complexes with various anions were investigated. The results show that receptor 4 can recognize selectively biologically important F- ion. The binding affinity for F- was investigated by naked-eye colour change, UV-Vis and 1H NMR spectroscopy. Addition F- ion in CH3CN and DMSO to receptor 4 cause a colour...
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Prosociality in relation to developmental tasks of emerging adulthood
PublicationProsociality, understood as the capacity to act in a way that benefits others, is an important feature for emerging adults to fulfill their personal needs and fulfill developmental tasks. This life period is a time of exploration within various areas of life, enabling individuals to try out and choose own worldview, lifestyle, work and preferred patterns of interpersonal relationships. This review aims at bringing together the...
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EU-Turkey Customs Union and Bilateral Foreign Direct Investment Flows
PublicationMain aim of this text is presentation of the effects of customs union between the European Union and turkey on bilateral FDI flows in light of the theory of linkages between economic integration and FDI flows. First section of the text is a survey of main theoretical links between economic integration and FDI flows. Second section focuses on the history and scope of the customs union. Third and fourth sections are empirical and...
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Mathematical model of pennate muscle
PublicationThe purpose of this study is to create a new mathematical model of pennate striated skeletal muscle. This new model describes behaviour of isolated flat pennate muscle in two dimensions (2D) by taking into account that rheological properties of muscle fibres depend on their planar arrangement. A new mathematical model is implemented in two types: 1) numerical model of unipennate muscle (unipennate model); 2) numerical model of...
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Modern Material Solutions Applied in Pediatric Facilities
PublicationNew tendencies in forming of the health services functional buildings’ systems shaped along with the emergence of caring for patient’s mental condition in medical sciences. The interior design harmonized with the medical function became an incredibly important feature. This opened up new opportunities for the architecture of health care facilities. A positive architecture’s impact on the user’s well-being is remarkably important...
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Effect of operating conditions on N 2 O production in an anammox sequencing batch reactor containing granular sludge
PublicationNitrous oxide (N2O) is one of the gases with the greatest impact in the atmosphere due to its persistence and significant contribution to the greenhouse effect. This study provides an insight into the dynamics of N2O production in wastewater nitrogen removal systems. A 10 L sequencing batch reactor containing enriched anammox biomass was subjected to different operational conditions, i.e., temperature, feed time, NO2 /NH4 þ ratio...
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Time evolution of Electrochemical Impedance spectra of cathodically protected steel in artificial seawater
PublicationUsability of Electrochemical Impedance Spectroscopy data for better cathodic protection control was investigated. Carbon steel – S235JR2 grade specimen were exposed in artificial seawater environment. Samples were polarized and their potentials corresponded to four different cathodic protection degrees. Time evolution of Electrochemical Impedance spectra was investigated. Goodness of fit function (X2) was analysed in terms of proper...
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Simulations of wave propagation and attenuation in fields of colliding ice floes
Open Research DataThis dataset contains results of numerical smulations of sea ice-wave interactions, corresponding to laboratory experiments conducted at the Large Ice Model Basin (LIMB) at the Hamburg Ship Model Basin (HSVA) as part of the LS-WICE ("Loads on Structure and Waves in Ice"; https://zenodo.org/record/1067170#.XrLt_dhpxhE) project. THe simulations were conducted...
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HDAC Inhibitors: Innovative Strategies for Their Design and Applications
PublicationHistone deacetylases (HDACs) are a large family of epigenetic metalloenzymes that are involved in gene transcription and regulation, cell proliferation, differentiation, migration, and death, as well as angiogenesis. Particularly, disorders of the HDACs expression are linked to the development of many types of cancer and neurodegenerative diseases, making them interesting molecular targets for the design of new efficient drugs...
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Solvent Exchange around Aqueous Zn(II) from Ab Initio Molecular Dynamics Simulations
PublicationHydrated zinc(II) cations, due to their importance in biological systems, are the subject of ongoing research concerning their hydration shell structure and dynamics. Here, ab initio molecular dynamics (AIMD) simulations are used to study solvent exchange events around aqueous Zn2+, for which observation in detail is possible owing to the considerable length of the generated trajectory. While the hexacoordinated Zn(H2O)62+ is the...
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Volunteerism in the last year as a moderator between empathy and altruistic social value orientation: An exploratory study
PublicationVolunteerism is a sustained prosocial activity, and young adults are one of the most important targets for organizations recruiting volunteers. Empathy and altruistic social value orientation measured by a decomposed game are dispositional traits that might foster engagement in volunteerism. Using a self-report online-based questionnaire study on two groups of young adults (aged 18-35, N = 224 non-volunteers and N = 178 volunteers...
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Influence of pyrolysis atmosphere on the lithium storage properties of carbon-rich polymer derived SiOC ceramic anodes
PublicationPolymer derived carbon-rich SiOC ceramics are prepared from polysiloxane precursors through a pyrolysis process at 1000 °C using pure argon and argon/hydrogen mixture as pyrolysis atmosphere. The precursor is synthesized from a linear (Si–H)-containing polysiloxane cross-linked with divinylbenzene using hydrosilylation reaction in the presence of a platinum catalyst. Pyrolysis in Ar/H2 mixtures, compared to the treatment under...
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Progress in used tyres management in the european union: a review
PublicationThe dynamic increase in the manufacture of rubber products, particularly those used in the automobile industry, is responsible for a vast amount of wastes, mostly in the form of used tyres, of which more than 17 million tonnes are produced globally each year. The widely differing chemical compositions and the cross-linked structures of rubber in tyres are the prime reason why they are highly resistant to biodegradation, photochemical...
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New recombinant chimeric antigens, P35-MAG1, MIC1-ROP1, and MAG1-ROP1, for the serodiagnosis of human toxoplasmosis
PublicationThe aim of the study was to evaluate the usefulness of 3 chimeric Toxoplasma gondii antigens, P35-MAG1,MIC1-ROP1 andMAG1-ROP1, in the serodiagnosis of an acute toxoplasmosis in humans. Proteins were produced as fusion proteins containing His tags ends and then further purified by metal affinity chromatography. Their application for the diagnosis of recently acquired T. gondii infection was tested in IgG and IgM enzyme-linked immunosorbent...
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Direct brain stimulation modulates encoding states and memory performance in humans
PublicationPeople often forget information because they fail to effectively encode it. Here, we test the hypothesis that targeted electrical stimulation can modulate neural encoding states and subsequent memory outcomes. Using recordings from neurosurgical epilepsy patients with intracranially implanted electrodes, we trained multivariate classifiers to discriminate spectral activity during learning that predicted remembering from forgetting,...
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Improving social competencies of architecture students through participatory design of marketplace regeneration
PublicationThe article discusses the involvement of architecture students in actual urban regeneration projects through participatory design and tray to respond question how it can improve students social competences, and benefit their future careers as architects and urban planners. By using the example of the student workshops conducted in 2019 at the Faculty of Architecture, GdanskTech, the article discusses the specific methods applied...
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Reactive extrusion of biodegradable aliphatic polyesters in the presence of free-radical-initiators: A review
PublicationNowadays, growing attention is being paid to the environment and sustainability, what fully justified research works focused on modification of biodegradable polymers and their composites. In this field of research reactive extrusion seems to be the most promising approach, which fits well to sustainable development strategy. In In the present work, the in-situ modification of biodegradable aliphatic polyesters and the compatibilization...
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9-Cyano-10-methylacridinium hydrogen dinitrate
PublicationThe title compound, C15H11N2+·HN2O6−, crystallizes in the monoclinic space group C2/c with four molecules in the unit cell. The planar 9-cyano-10-methylacridinium cations lie on crystallographic twofold axes and are arranged in layers, almost perpendicular to the ac plane, in such a way that neighbouring molecules are positioned in a `head-to-tail' manner. These cations and the hydrogen dinitrate anions are linked through C—H⋯O...
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Zarządzanie wiedzą w małych przedsiębiorstwach oferujących wiedzochłonne usługi biznesowe
PublicationCelem artykułu jest przedstawienie praktyk zarządzania wiedzą oraz czynników wpływających na sukces, bądź porażkę w ich wdrażaniu na podstawie badania jakościowego przeprowadzonego w trzech firmach działających na terenie województwa pomorskiego. Firmy te należą do sektora małych i średnich przedsiębiorstw oraz oferują wiedzochłonne usługi biznesowe (knowledge-intensive business services – KIBS). W artykule podjęto próbę odpowiedzi...
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Missing Puzzle Pieces in Dementia Research: HCN Channels and Theta Oscillations
PublicationIncreasing evidence indicates a role of hyperpolarization activated cation (HCN) channels in controlling the resting membrane potential, pacemaker activity, memory formation, sleep, and arousal. Their disfunction may be associated with the development of epilepsy and age-related memory decline. Neuronal hyperexcitability involved in epileptogenesis and EEG desynchronization occur in the course of dementia in human Alzheimer’s Disease...
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Treatment of Odontogenic Maxillary Sinusitis with the Use of Growth Factors in Advanced Platelet-Rich Fibrin for Immediate Closure of Oro-Antral Communication: A Case Report
PublicationChronic odontogenic maxillary sinusitis (COMS), a prolonged inflammation of the maxillary sinus lasting over 12 weeks, is often a result of periapical lesions, marginal periodontitis, and complications like oro-antral communication (OAC) and fistula (OAF). OAC, commonly emerging post-teeth extraction in the lateral maxilla, lacks documented treatments using advanced platelet-rich fibrin (A-PRF). This study evaluates A-PRF’s efficacy...
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Formation of Protein Networks between Mucins: Molecular Dynamics Study Based on the Interaction Energy of the System
PublicationMolecular dynamics simulations have been performed for a model aqueous solution of mucin. As mucin is a central part of lubricin, a key component of synovial fluid, we investigate its ability to form cross-linked networks. Such network formation could be of major importance for the viscoelastic properties of the soft-matter system and crucial for understanding the lubrication mechanism in articular cartilage. Thus,the inter- and...
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Photonic sensor to detect rapid changes in CRP levels
PublicationOne of the most important biomarkers used to determine inflammation is C-reactive protein (CRP). Its level, when it is within the range that does not define inflammation, informs about the risk of cardiovascular events. If the norm is exceeded and inflammation is detected in the body, CRP level can increase 1000 times within a few hours. The type of infection can also be determined based on the level of elevated CRP. All this makes...
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The Impact of Thermal Stresses on Volume Resistivity: Performance Comparison between TR-XLPE and XLPE Cables
PublicationMost failures in electric power cables are attributed to the development of water trees inside the insulating materials. Thus, the development and utilization of Tree Retardant Cross-Linked Polyethylene (TR-XLPE) based cables have recently been given great attention to overcome the treeing issues. TR-XLPE cables use low-density polyethylene compounds suppressing the formation of water trees while retaining excellent electrical,...
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Stabalization of solar-panel energy system for Pakistani household
PublicationRenewable energy resources such as Sun and wind are getting popular and easier to use day by day. It is a better method to fulfill our demands as sun is a continuous source of energy for Earth. Many countries are fulfilling their demands by Solar Panels. Solar panel is used as a converter between sunlight and electrical energy. This research paper is going to tell that how to obtain electrical energy from sunlight more efficiently...
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Emotional distress, burnout and sense of safety during the COVID-19 pandemic in teachers after the reopening of schools
PublicationThe COVID-19 pandemic is having a significant impact on people's psychological well-being and mental health. This study aimed to identify factors linked to emotional distress, burnout and sense of safety in teachers related to the reopening of Polish schools after lockdown, remote work, and the holiday period between March and August 2020. A total of 1,286 teachers from different educational institutions participated in the...
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What is important for you makes you think about the pandemic differently: moral foundations, pandemic-related fears and convictions (Lo que cada uno consideramos importante nos hace reflexionar sobre la pandemia de forma distinta: fundamentos morales, temores y convicciones sobre la pandemia)
PublicationBuilding on the Moral Foundations Theory and findings regarding the linkage of values, convictions and beliefs, the aim of the study was to compare people displaying various constellations of moral foundations regarding their tolerance of ambiguity, fear of COVID-19 (FCV), endorsement of COVID-19 conspiracy theories and the extent to which they believed in the effectiveness of five COVID-19 preventive measures. This study was...
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Modification of thermal and rheological characteristics of bitumen by waste PET/GTR blends
PublicationWaste poly(ethylene terephthalate) (wPET)/ground tire rubber (GTR) blends with variable compositions were applied as low-cost modifiers into bitumen and their performance has been evaluated via morphological, thermal and rheological analyses. Depending on the weight ratio of wPET/GTR, dispersion of single/composite domains of waste polymers in the bitumen has promoted the interaction between bitumen and blend components. Fourier...
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Synthesis of Combretastatin A-4 Analogs and their Biological Activities
PublicationCombretastatin A-4 (CA-4) is a natural product, which consists of two phenyl rings, linked by an ethylene bridge. CA-4, inhibitor of polymerization of tubulin to microtubules, possesses a strong antitumor and anti-vascular properties both in vitro and in vivo. Previous studies showed that disodium phosphate salt of CA-4, a water-soluble prodrug is well tolerated at therapeutically useful doses. However, it should be noted that...
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Criteria for selection of working fluid in low-temperature ORC
PublicationThe economics of an ORC system is strictly linked to thermodynamic properties of the working fluid. A bad choice of working fluid could lead to a less efficient and expensive plant/generation unit. Some selection criteria have been put forward by various authors, incorporating thermodynamic properties, provided in literature but these do not have a general character. In the paper a simple analysis has been carried out which resulted...