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Performance of lubricated sliding contact in magnetic field
PublikacjaResults of experimental studies concerning theinfluence of permanent magnetic field on wear of lubricatedsliding contact operating at short stroke and highfrequency are presented. It was found that horizontalmagnetic is affecting performance of the contact. Thejagged delamination regions produced in the presence of amagnetic field can be regarded as easily undergoing oxidisationbecause oxygen is readily adsorbed there. Magneticfield...
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On the Disaster Resiliency within the Context of 5G Networks : The RECODIS Experience
PublikacjaNetwork communications and the Internet pervade our daily activities so deeply that we strongly depend on the availability and quality of the services they provide. For this reason, natural and technological disasters, by affecting network and service availability, have a potentially huge impact on our daily lives. Ensuring adequate levels of resiliency is hence a key issue that future network paradigms, such as 5G, need to address. This...
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Targeting yeast topoisomerase II by imidazo and triazoloacridinone derivatives resulting in their antifungal activity
PublikacjaFungal pathogens are considered as serious factors for deadly diseases and are a case of medical concern. Invasive fungal infections also complicate the clinical course of COVID-19, leading to a significant increase in mortality. Furthermore, fungal strains' multidrug resistance has increased the demand for antifungals with a different mechanism of action. The present study aimed to identify antifungal compounds targeting yeast...
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Morphology, Photocatalytic and Antimicrobial Properties of TiO2 Modified with Mono- and Bimetallic Copper, Platinum and Silver Nanoparticles
PublikacjaNoble metal nanoparticles (NMNPs) enhanced TiO2 response and extended its activity under visible light. Photocatalytic activity of TiO2 modified with noble metal nanoparticles strongly depends on the physicochemical properties of NMNPs. Among others, the differences in the size of NMNPs seems to be one of the most important factors. In this view, the effect of the metal’s nanoparticles size, type and amount on TiO2 photocatalytic...
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Two-step mechanism of J-domain action in driving Hsp70 function
PublikacjaJ-domain proteins (JDPs), obligatory Hsp70 cochaperones, play critical roles in protein homeostasis. They promote key allosteric transitions that stabilize Hsp70 interaction with substrate polypeptides upon hydrolysis of its bound ATP. Although a recent crystal structure revealed the physical mode of interaction between a J-domain and an Hsp70, the structural and dynamic consequences of J-domain action once bound and how Hsp70s...
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Camera angle invariant shape recognition in surveillance systems
PublikacjaA method for human action recognition in surveillance systems is described. Problems within this task are discussed and a solution based on 3D object models is proposed. The idea is shown and some of its limitations are talked over. Shape description methods are introduced along with their main features. Utilized parameterization algorithm is presented. Classification problem, restricted to bi-nary cases is discussed. Support vector...
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Sąd zaangażowany społecznie - pożądany kierunek zmian
PublikacjaProblematyka książki wpisuje się w najnowsze nurty dyscypliny naukowej jaką stanowi zarządzanie publiczne. W ramach tej dyscypliny Autor zajął się zarządzaniem sądami - a ściśle jego obszarem związanym z zaangażowanie społecznym i relacjami z interesariuszami. Zastosowano innowacyjne i dynamiczne podejście do analizowanych zagadnień wykorzystując najnowszą literaturę krajową i zagraniczną. Przeprowadzono i opisano szeroko zakrojone...
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Fatty acids as molecular carriers in cleavable antifungal conjugates
PublikacjaConjugates composed of C2-18 fatty acid (FA) residues as a molecular carrier and 5-fluorocytosine (5-FC) as an active agent, released upon the action of intracellular esterases on the ester bond between FA and “trimethyl lock” intramolecular linker, demonstrate good in vitro activity against human pathogenic yeasts of Candida spp. The minimal inhibitory concentrations (MIC) values for the most active conjugates containing caprylic...
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Tax Policy Tools of Selected European Countries as a Mechanism for Counteracting the Effects of the Crisis Caused by the COVID-19 Disease Pandemic
PublikacjaCrises play an important role in a economics life. They are common and it is impossible to omit them. This following study investigates the concept of ‘crisis’ in the context of economic situation. This text describes the most important financial crises that took place in the past. After that authors passes on a detailed analysis of the actual corona-crisis and the way that it affects the economy globally. The main goal of this...
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Intercalation complex of imidazoacridinone C-1311, a potential anticancer drug, with DNA helix d(CGATCG)2: stereostructural studies by 2D NMR spectroscopy.
PublikacjaImidazoacridinone C-1311 (Symadex®) is a powerful antitumor agent, which successfully made its way through the Phase I clinical trials and has been recommended for Phase II few a years ago. It has been shown experimentally that during the initial stage of its action C-1311 forms a relatively stable intercalation complex with DNA, yet it has shown no base-sequence specificity while binding to DNA. In this paper, the d(CGATCG)2:C-1311...
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Transparent nanocomposite coatings based on epoxy and layered double hydroxide: Nonisothermal cure kinetics and viscoelastic behavior assessments
PublikacjaLayered double hydroxide (LDH) has a particular place in clay family because of its flame retardant action. The nanoplatelet-like structure of LDH makes possible development of polymer composites with cationic or anionic nature structures in which macromolecules are positioned in between nanoplatelet galleries. In this work, neat epoxy and its transparent nanocomposite coatings with sodium dodecylbenzene sulfonate (SDBS)-modified...
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Size-Controlled Synthesis of Pt Particles on TiO2 Surface: Physicochemical Characteristic and Photocatalytic Activity
PublikacjaDifferent TiO2 photocatalysts, i.e., commercial samples (ST‐01 and P25 with minority of rutile phase), nanotubes, well‐crystallized faceted particles of decahedral shape and mesoporous spheres, were used as supports for deposition of Pt nanoparticles (NPs). Size‐controlled Pt NPs embedded in TiO2 were successfully prepared by microemulsion and wet‐impregnation methods. Obtained photocatalysts were characterized using XRD, TEM,...
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The Effectiveness of Basic Resuscitation Activities Carried out by Combat Paramedics of the Police, as Exemplified by Polish Counterterrorist Units
PublikacjaThe tasks carried out by Police officers are often accompanied by dangerous situations that threaten the life and health of the people involved, the police themselves, and bystanders. It concerns especially counter-terrorism police units whose activities are aimed at terrorists and particularly dangerous criminals, and their course is violent and aggressive. In conjunction with the inability to bring civilian rescue services into...
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On the Fenchel–Moreau conjugate of G-function and the second derivative of the modular in anisotropic Orlicz spaces
PublikacjaIn this paper, we investigate the properties of the Fenchel–Moreau conjugate of G-function with respect to the coupling function c(x, A) = |A[x]2 |. We provide conditions that guarantee that the conjugate is also a G-function. We also show that if a G-function G is twice differentiable and its second derivative belongs to the Orlicz space generated by the Fenchel–Moreau conjugate of G then the modular generated by G is twice differentiable...
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Weldability of high strength steels in wet welding conditions
PublikacjaIn this paper are characterized problems of high strength steel weldability in underwater wet welding conditions. Water as a welding environment intensifies action of unfavourable factors which influence susceptibility to cold cracking of welded steel joints. The susceptibility to cold cracking of S355J2G3 steel and S500M steel in wet conditions was experimentally estimated (by using Tekken test). It was concluded that the steels...
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KM supported process improvement
PublikacjaThe corporate universe nowadays is full of change initiatives andimprovement philosophies. However,only few have proved successful enough to be integrated into regular operations a worldwide leading companies.In this context Six Sigma projects and Lean action workouts emerge as he most effective practices.In this paper we argue that there is a considerable potential to enhance them using Knowledge Management methodology and benefit...
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Methodology for assessing end-user requirements in the Ella4Life project: elders’ perspectives about self-monitoring
PublikacjaThe purpose of this paper is to explore elders’ perspectives about self-monitoring and using specially developed sensor technology for measuring health indicators. The qualitative research method is focus-groups with guidelines that were designed for understanding elder’s requirements about monitoring health indicators. We present them two devices: the first sensor is a device for monitoring of cardiac action potential fixed into...
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Antioxidants: a premature scientific hypothesis that reshuffled the traditional food pyramid
PublikacjaAntioxidants present in substantial amounts in foods, plant-based products in particular, have been suggested as chemopreventive agents that can curb the development of undesirable health effects caused by oxidative stress simply by enriching diet in such compounds. This idea has been enthusiastically accepted by consumers, as well as food and pharmaceutical industry, and created great demand for products containing antioxidant...
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A Universal Theory of Wisdom . A Mind - oriented Approach
PublikacjaThe purpose of the paper is to synthesize the issues of human wisdom in terms of minds which create knowledge-based judgment. We form a transdisciplinary, big-picture view of the wisdom of humans. Findings: Wisdom is the right judgment and choice in the context of the art of living. Practical implications: Wisdom can be developed within the set of minds. Social implications: To pursue wisdom in thinking and action, one must extend...
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Metabolic transformation of antitumor acridinone C-1305 but not C-1311 via selective cellular expression of UGT1A10 increases cytotoxic response: implications for clinical use.
PublikacjaThe acridinone derivates C-1305 and C-1311 are promising antitumor agents with high activity against several experimental cellular and tumor models and which are under evaluation in pre-clinical and early phase clinical trials. Recent evidence from our laboratories has indicated that both compounds were conjugated by several UGT isoforms with the most active being extrahepatic UGT1A10. The present studies were designed to test...
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Study of anticorrosion and microwave absprption properties of NiZn ferrite pigments
PublikacjaPurpose - The purpose of this paper is to report the electrochemical verification of anticorrosive properties of NiZn ferrites as pigments in protective coatings and evaluation of their microwave absorbing properties. Design/methodology/approach - Ferrites, represented by formula NixZn(1-x)Fe2O4, where x=0, 0.2, 0.4, 0.6, 0.8, 1.0, were synthesized using a ceramic method. The samples of ferrites were examined by X-ray diffraction...
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Control of the bridge span vibration with high coefficient passive damper. Theoretical consideration and application
PublikacjaThe research was carried out due to the problem of vibration on the lively pedestrian drawbridge across the Motlawa River in the city of Gdansk. In the design stage, the main span of the footbridge showed unfavorable dynamic properties, which may create a comfort problem for pedestrians. The first vertical bending eigenfrequency was recognized as 1.64 Hz. The original design of the footbridge was equipped with a driving cylinder...
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City scan as a tool to assess resilience challenges and vulnerabilities at the community level
PublikacjaThe majority of the world’s population lives in cities and cities are the key to achieving resilience. Local governments own only part of the land and can only partially decide about measures that should be taken ‘on the ground’. Local governments are therefore highly dependent on individuals, communities, and businesses to adapt and transform and take action in their own backyards or neighbourhoods. Since, for many people, climate...
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Old Problems - New Solutions: Conversion of Capitals as a Tool for Shaping the Competitive Position in the Economic Field
PublikacjaThe acts and operations any social actor effectuates in each of the logically distinguished spheres of reality are conditioned by many factors, among which a reliable analysis of the strengths and weaknesses of an agent should be considered of utmost importance. The concept of capitals presented in this article divides the quantity of resources available to all acting agents into four main categories (which allows for determining...
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Old Problems - New Solutions: Conversion of Capitals as a Tool for Shaping the Competitive Position in the Economic Field
PublikacjaThe acts and operations any social actor effectuates in each of the logically distinguished spheres of reality are conditioned by many factors, among which a reliable analysis of the strengths and weaknesses of an agent should be considered of utmost importance. The concept of capitals presented in this article divides the quantity of resources available to all acting agents into four main categories (which allows for determining...
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REVITALIZATION PROJECT OF SLUM TRANSFORMATION: A CASE STUDY HAY-AL TANAK,BEIRUT,LEBANON
PublikacjaSlums are global phenomena that exist as a solution for those who couldn’t afford a house. This phenomenon is growing accompanying the rapid urbanization and the growth of the urban population, three-quarter of the world population anticipated to live in an urban environment by 2050 (Avis, 2016, p. 57). This paper reviews slum's evaluation of the revitalization project for one of the poorest slums in Beirut called Hay-Al Tanak....
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Dataset Characteristics and Their Impact on Offline Policy Learning of Contextual Multi-Armed Bandits
PublikacjaThe Contextual Multi-Armed Bandits (CMAB) framework is pivotal for learning to make decisions. However, due to challenges in deploying online algorithms, there is a shift towards offline policy learning, which relies on pre-existing datasets. This study examines the relationship between the quality of these datasets and the performance of offline policy learning algorithms, specifically, Neural Greedy and NeuraLCB. Our results...
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Approaches Towards Better Immunosuppressive Agents
PublikacjaSeveral classes of compounds are applied in clinics due to their immunosuppressive properties in transplantology and the treatment of autoimmune diseases. Derivatives of mycophe-nolic acid, corticosteroids and chemotherapeutics bearing heterocyclic moieties like methotrexate, azathioprine, mizoribine, and ruxolitinib are active substances with investigated mechanisms of action. However, improved synthetic approaches of known drugs...
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RNDM 2016 Workshop and 2nd Meeting of COST CA15127-RECODIS: Highlights from the Resilience Week in Halmstad, Sweden
PublikacjaLeading network resilience researchers took part in the Resilience Week on Sept. 12-15, 2016 at Halmstad University, SE by Prof. Magnus Jonsson from the Centre for Research on Embedded Systems (CERES), Halmstad University, SE, and Prof. Jacek Rak from Gdansk University of Technology, PL. It included two major events: - The 2nd Meeting of COST CA15127–RECODIS Action (Resilient Communication Services Protecting End-user Applications...
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Move into the open space – what can we expect from moving artistic interventions to open urban spaces?
PublikacjaThe paper discuses the role of incorporating creative engagement into the processes of urban and social development using cultural means of action and expression and the potential of artistic interventions in public space. The block of initiatives within the People’s Smart Sculpture EU project, realized by Gdańsk City Gallery, has been named “Move Into The Open Space”. This paper will provide...
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Ionosphere variability II: Advances in theory and modeling
PublikacjaThis paper aims to provide an overview on recent advances in ionospheric modeling capabilities, with the emphasis in the efforts relevant to electron density variability. The discussion spans a wide range of model formulations (e.g., from purely empirical to physics-based ones and data-driven approaches) seeking for advances or gaps with regard to present challenges. This discussion is further supported by consideration of the...
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Extending touch-less interaction with smart glasses by implementing EMG module
PublikacjaIn this paper we propose to use temporal muscle contraction to perform certain actions. Method: The set of muscle contractions corresponding to one of three actions including “single-click”, “double-click” “click-n-hold” and “non-action” were recorded. After recording certain amount of signals, the set of five parameters was calculated. These parameters served as an input matrix for the neural network. Two-layer feedforward neural...
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Monitoring system of the road embankment
PublikacjaThe paper presents the monitoring system of the embankment supported on concrete columns and overlaid by a load transfer platform (LTP) with the embedded steel grid. This field investigation was to study the complex inter-action between the columns, the LTP layer, and steel reinforcement via full-scale in situ measurements during erection of the embankment. The study was focused on the behaviour of steel reinforcement and the behaviour...
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X-ray Photoelectron Spectroscopy of Carboxylic Acids as Corrosion Inhibitors of Aluminium Alloys
PublikacjaThe datasets, titled X-ray Photoelectron Spectroscopy studies of citric acid adsorption on aluminium alloy 5754 in alkaline media and X-ray Photoelectron Spectroscopy studies of various carboxylic acids adsorption on aluminium alloys in alkaline media, contain XPS studies of the corrosion inhibitory action of selected dicarboxylic acids towards commercially available aluminium alloy 5754 in alkaline media at pH=11. These datasets...
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Safety assurance strategies for autonomous vehicles
PublikacjaAssuring safety of autonomous vehicles requires that the vehicle control system can perceive the situation in the environment and react to actions of other entities. One approach to vehicle safety assurance is based on the assumption that hazardous sequences of events should be identified during hazard analysis and then some means of hazard avoidance and mitigation, like barriers, should be designed and implemented. Another approach...
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Optymalizacja systemu zarządzania uszkodzeniami węzłów komutacyjnych.
PublikacjaW referacie przedstawiono wyniki analizy funkcjonalnej ystemu węzłów komutacyjnych systemu 5ESS. Na podstawie tej analizy dokonano oceny funkcjonowania systemu zarządzania i wskazano obszary jegooptymalizacji. Zaproponowano ssposób wykorzystania narzędzia Action Request System do tworzenia bazy danych raportów alarmowych. Zaproponowano strukturę bazy danych raportów alarmowych i formularza zgłaszania problemu do tworzenia w tej...
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Ionosphere variability I: Advances in observational, monitoring and detection capabilities
PublikacjaThe paper aims to review recent advances regarding the observational and monitoring capabilities of the ionization conditions in the Earth's upper atmosphere. The analysis spans both ground and space-based experiments, seeking for new installations and/or missions, new or upgraded instrumentation and/or observational network establishments as means for advancing current understanding and prediction ability of the ionosphere variability....
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Mechanism of the Reaction of Amines with 5-[(Aryl- or Alkylamino)hydroxymethylene]-2,2-dimethyl-1,3-dioxane-4,6-diones in the Presence of Chlorotrimethylsilane (Me3SiCl);
PublikacjaAddition of chlorotrimethylsilane (Me3SiCl) to the mixture of a carbamoyl‐substituted Meldrum's acid, i.e., a 5‐[(arylamino)hydroxymethylene]‐2,2‐dimethyl‐1,3‐dioxane‐4,6‐dione of type 1 and a secondary amine as nucleophile strongly accelerated the rate of their reaction. The reason for this phenomenon observed, during our previous research, remained, however, unclear. To elucidate the mechanism of this reaction, we assumed and...
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Directed electromagnetic pulse dynamics: projecting operators method
PublikacjaIn this article, we consider a one-dimensional model of electromagnetic pulse propagation in isotropic media, takinginto account a nonlinearity of the third order. We introduce a method for Maxwell's equation transformation on thebasis of a complete set of projecting operators. The operators correspond to wave dispersion branches including thedirection of propagation. As the simplest result of applying the method, we derive a system...
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Effect of Thermal Shock During Legionella Bacteria Removal on the Corrosion Properties of Zinc-Coated Steel Pipes
PublikacjaThe purpose of this investigation was to conduct the failure analysis of a water-supply system made from zinc-coated steel. The observed corrosion process had an intense and complex character. The brownish deposits and perforations were present after 2-3 years of exploitation. The electrochemical study based on the Tafel polarization, corrosion potential monitoring, and electrochemical impedance spectroscopy together with microscopic...
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Amyloid fibril formation in the presence of water structure-affecting solutes
PublikacjaThe impact of the differently hydrated non-electrolytes (protein structure destabilizers) on the fibrillation of hen egg white lysozyme (HEWL) was investigated. Two isomeric urea derivatives i.e. butylurea (BU) and N,N,N′,N′-tetramethylurea (TMU) were chosen as a tested compounds. The obtained results show that butylurea exerts greater impact on HEWL and its fibrillation than tetramethylurea. Both substances decrease the time of...
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A new approach of coastal cliff monitoring using Mobile Laser Scanning
PublikacjaThe article proposes a new approach of coastal cliff monitoring which bases on a new comprehensive monitoring system, being a combination of mobile scanning from the sea with the geotechnical stability analysis. Mobile laser scanning is an innovative solution for 3D data collection which allows the monitored object geometry to be precisely measured, thus providing opportunities for series of analyses contributing to the development...
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Antifungal dipeptides incorporating an inhibitor of homoserine dehydrogenase
PublikacjaThe antifungal activity of 5‐hydroxy‐4‐oxo‐L‐norvaline (HONV), exhibited under conditions mimicking human serum, may be improved upon incorporation of this amino acid into a dipeptide structure. Several HONV‐containing dipeptides inhibited growth of human pathogenic yeasts of the Candida genus in the RPMI‐1640 medium, with minimal inhibitory concentration values in the 32 to 64 μg mL−1 range. This activity was not affected by multidrug...
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ENERGY ANALYSIS OF THE PROPULSION SHAFT FATIGUE PROCESS IN A ROTATING MECHANICAL SYSTEM PART III DIMENSIONAL ANALYSIS
PublikacjaThis article presents the third and last part of the problem of diagnosing the fatigue of marine propulsion shafts in terms of energy with the use of the action function, undertaken by the authors. Even the most perfect physical models of real objects, observed under laboratory conditions and developed based on the results of their research, cannot be useful in diagnostics without properly transferring the obtained results to the...
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Membrane Sterols Modulate the Binding Mode of Amphotericin B without Affecting Its Affinity for a Lipid Bilayer
PublikacjaMembrane-active antibiotics are known to selectively target certain pathogens based on cell membrane properties, such as fluidity, lipid ordering, and phase behavior. These are in turn modulated by the composition of a lipid bilayer and in particular by the presence and type of membrane sterols. Amphotericin B (AmB), the golden standard of antifungal treatment, exhibits higher activity toward ergosterol-rich fungal membranes, which...
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Low temperature processed MnCo2O4 and MnCo1.8Fe0.2O4 as effective protective coatings for solid oxide fuel cell interconnects at 750 °C
PublikacjaIn this study two materials, MnCo2O4 and MnCo1.8Fe0.2O4 are studied as potential protective coatings for Solid Oxide Fuel Cell interconnects working at 750 °C. First powder fabrication by a modified Pechini method is described followed by a description of the coating procedure. The protective action of the coating applied on Crofer 22 APU is evaluated by following the area specific resistance (ASR) of the scale/coating for 5500...
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Workflow patterns applicable to virtual knowledge-based organizations
PublikacjaWorkflow is a term specifying how to automate a business process, in whole or part during which documents, information or tasks are passed from one participant to another for action, according to a set of procedural rules. Workflow is therefore directly applicable in virtual knowledge-based organizations, where information is exchanged via electronic documents. In the literature, is presented a complete list of workflow control-flow...
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Cell-penetrating peptides – mechanism of transduction and synthesis – short review
PublikacjaPotential antimicrobial agents may be effective if they are delivered efficiently to their site of action. In many cases, lack of permeability through the cell membrane is the main problem. One of the possible solutions could be a novel intracellular delivery system involving cell-penetrating peptides (CPPs), which may improve the efficiency of many new biophar-maceuticals. Among other things, CPPs are capable of trans-porting...
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MutL protein as a constituent of vsp, ner and mmr repair systems
PublikacjaMutS and MutL proteins are renowned mostly for their functions in well-characterized, post-DNA replication mis- match repair system (MMR). However, there is growing evidence that MMR system is not the only field of action for these pro- teins. Moreover, the participation in MMR does not even have to be their primary function. There are some reports indicat- ing involvement of MutL in BER, NER and VSP (very short patch repair)....
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Comparative molecular modelling of biologically active sterols
PublikacjaMembrane sterols are targets for a clinically important antifungal agent – amphotericin B. The relatively specific antifungal action of the drug is based on a stronger interaction of amphotericin B with fungal ergosterol than with mammalian cholesterol. Conformational space occupied by six sterols has been defined using the molecular dynamics method to establish if the conformational features correspond to the preferential interaction...