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Wyniki wyszukiwania dla: controlled drug delivery
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The luminescence study of Ga2–x(Al0.68In0.32)xO3:Cr3+ coumpounds.
Dane BadawczeNear-infrared (NIR) phosphor-converted light-emitting diodes (pc-LEDs) are a highly efficient perspective NIR light source, with application hindered by a narrow emission band. In this work, we broaden the emission of a new series of NIR phosphors by controlling crystal structure disorder through cation cosubstitution. By substituting Ga3+ with (Al0.68In0.32)3+,...
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D.C. electrical measurements of Bi2VO5.5 ceramic measured at high temperature region
Dane BadawczeD.C. electrical properties of Bi2VO5.5 ceramic was measured.
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Tailoring the electrochemical degradation of iron protected with polypyrrole films for biodegradable cardiovascular stents
PublikacjaThe degradation of polypyrrole (PPy) coated iron is studied in phosphate buffer saline solution at 37 °C by odd random phase multisine electrochemical impedance spectroscopy (ORP-EIS). PPy is electropolymerized with anti-inflammatory salicylates incorporated in the film, as a drug release system. The modelling of EIS over time provides the quantitative description of the corrosion behaviour of the material. Thus, the reliable...
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MAPSERVER – INFORMATION FLOW MANAGEMENT SOFTWARE FOR THE BORDER GUARD DISTRIBUTED DATA EXCHANGE SYSTEM
PublikacjaIn this paper the architecture of the software designed for management of position and identification data of floating and flying objects in Maritime areas controlled by Polish Border Guard is presented. The software was designed for managing information stored in a distributed system with two variants of the software, one for a mobile device installed on a vessel, an airplane or a car and second for a central server. The details...
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AEGIS - demonstrator technologii C-IED
PublikacjaW referacie przedstawiono budowę i działanie opracowanego w Politechnice Gdańskiej demonstratora technologicznego systemu AEGIS, przeznaczonego do przeciwdziałania atakom z wykorzystaniem prowizorycznych urządzeń wybuchowych detonowanych drogą radiową (RCIED - Radio Controlled Improvised Explosive Devices). Przedstawiono zaimplementowaną oryginalną metodę generowania sygnału zagłuszającego o dowolnie ukształtowanym widmie częstotliwościowym,...
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Mobilny demonstrator technologii wytwarzania kurtyny elektromagnetycznej do ochrony przed urządzeniami IED
PublikacjaW referacie przedstawiono budowę i działanie opracowanego w Politechnice Gdańskiej demonstratora technologicznego systemu AEGIS, przeznaczonego do przeciwdziałania atakom z wykorzystaniem prowizorycznych urządzeń wybuchowych detonowanych drogą radiową (RCIED - Radio Controlled Improvised Explosive Devices). Przedstawiono zaimplementowaną oryginalną metodę generowania sygnału zagłuszającego o dowolnie ukształtowanym widmie częstotliwościowym,...
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A method of self-testing of analog circuits based on fully differential op-amps with theTCBF classifier
PublikacjaA new approach of self-testing of analog circuits based on fully differential op-amps of mixed-signal systems controlled by microcontrollers is presented. It consists of a measurement procedure and a fault diagnosis procedure. We measure voltage samples of a time response of a tested circuit on a stimulation of a unit step function given at the common-mode reference voltage input of the op-amp. The fault detection and fault localization...
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AEGIS — demonstrator technologii C-IED
PublikacjaW artykule przedstawiono budowę i działanie opracowanego na Politechnice Gdańskiej demonstratora technologicznego systemu AEGIS, przeznaczonego do przeciwdziałania atakom z wykorzystaniem prowizorycznych urządzeń wybuchowych detonowanych drogą radiową (RCIED — Radio Controlled Improvised Explosive Devices). Przedstawiono zaimplementowaną oryginalną metodę generowania sygnału zagłuszającego o dowolnie ukształtowanym widmie częstotliwościowym,...
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Evolution of chemotaxis in single-cell artificial organisms
PublikacjaThe model of a liquid two-dimensional environment, which is based on physics of diffusion, allows us to simulate the diffusion of morphogenes. Artificial organisms move using a chemotaxis reacting to concentration difference. Organisms are controlled by a gene regulatory network coded in a linear genome and reproduce by division. We made a lot of experiments presenting organisms’ behaviour in various environment conditions. We...
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State Observer for Doubly-fed Induction Generator
PublikacjaIn the paper a new state observer for doubly-fed generator has been proposed. In the new approach an extended mathematical model of the doubly fed generator is used to form equations of the introduced z type observer. Stability of the observer has been verified through poles placement analyses. The active and reactive powers of the generator are controlled by a nonlinear multiscalar control method. Simulation and experimental results...
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Synthesis and biological activity of ester derivatives of mycophenolic acid and acridines/acridones as potential immunosuppressive agents
PublikacjaImproved derivatives of mycophenolic acid (MPA) are necessary to reduce the frequency of adverse effects, this drug exerts in treated patients. In this study, MPA was coupled with N-(x-hydroxyalkyl)-9-acridone-4-carboxamides or N-(x-hydroxyalkyl)acridine-4-carboxamides to give respective ester conjugates upon Yamaguchi protocol. This esterification required protection of phenol group in MPA. Designed conjugates revealed higher...
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Scalable Measurement System for Multiple Impedance Gas Sensors
PublikacjaAuthor proposes scalable architecture of the measurement system for gas sensor with impedance dependance of the gas concentration. The main part of the system is a single-board impedance analyser. The number of analysers working in parallel can be configured according to specific application. The system is controlled by a single computer which organises the measurement cycle and store the acquired measurement data. The system is...
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Multi-headed chimera states in coupled pendula
PublikacjaWe discuss the occurrence of the chimera states in the network of coupled, excited by the clock’s mechanisms pendula. We find the patterns of multi-headed chimera states in which pendula clustered in different heads behave differently (oscillate with different frequencies) and create different types of synchronous states (complete or phase synchronization). The mathematical model of the network shows that the observed chimera states...
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A Human Behaviour Model Agent for Testing of Voluntary Computing Systems
PublikacjaPaper presents a design and performance of a voluntary-based distributed computing system testing agent, implementing a human behaviour model. The agent, nicknamed iRobot, was designed and implemented to enable controlled, large scale testing of core algorithms of Comcute - a new voluntary distributed computing platform complementary to BOINC. The main agent design goals were: emulation of human behaviour when browsing web pages,...
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Small rov to detection and identification of dangerous underwater objects
PublikacjaA small unmanned underwater vehicle (UUV) to inspection of an undersea space is presented in the paper. Its behavior is controlled by a trained pilot. Correct detection and identification of targets depends on vehicle'sprecise displacement along a predefined route. Nowadays, the UUVs are equipped with an automatic control system to execute some basic maneuvers without constant human interventions. Hence, in the paper, an autopilot...
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The Concept of Geodetic Analyses of the Measurement Results Obtained by Hydrostatic Leveling
PublikacjaThe article discusses the issue of hydrostatic leveling. Its application is presented in structural health monitoring systems in order to determine vertical displacements of controlled points. Moreover, the article includes a complete computation scheme that utilizes the estimation from observation differences, allowing the elimination of the influence of individual sensors’ systematic errors. The authors suggest two concepts of...
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Control of a vapour microturbine set in cogeneration applications
PublikacjaSystems with microturbines are implemented for local generation of heat and electricity. This paper presents the analysis of control concepts for a vapour microturbine set with a generator with permanent magnets, intended to work in small heat and power plants. Control system variants differed by the selection of controlled signals and set parameters. Possible ways of control were discussed and compared with experimentally determined...
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Dietary intervention with beetroot juice during doxorubicin cancer chemotherapy in vivo reduces markers of oxidative stress
PublikacjaCancer chemotherapy with doxorubicin, despite high antitumor activity and broad spectrum of this drug, is on decline due to toxic side effects. The clinical efficacy of anthracyclines have continuously prompted the search for new adjuvants to alleviate undesirable side toxicity incurred by this group of cytostatics. The recent approaches involve the application of synthetic or purified natural antioxidants in combination with doxorubicin...
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Cell Density-Dependent Cytological Stage Profile and Its Application for a Screen of Cytostatic Agents Active Toward Leukemic Stem Cells
PublikacjaProliferation and expansion of leukemia is driven by leukemic stem cells (LSCs). Multidrug resistance (MDR) of LSCs is one of the main reasons of failure and relapses in acute myeloid leukemia (AML) treatment. In this study, we show that maintaining HL-60 at low cell culture density or applying a 240-day treatment with anthrapyridazone (BS-121) increased the percentage of primitive cells, which include LSCs determining the overall...
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Docking simulations, Molecular properties and ADMET studies of novel Chromane6,7diol analogues as potential inhibitors of Mushroom tyrosinase
PublikacjaResearch on inhibition of tyrosinase enzyme has attained significant value, because tyrosinase inhibitors have potential applications in medicine, cosmetics (as whitening agents) and in agriculture (as bioinsecticides). Determination and elucidation of new tyrosinase inhibitors are not only beneficial for medical purposes, but their promising applications in improving food quality and nutritional...
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Intermolecular Interactions as a Measure of Dapsone Solubility in Neat Solvents and Binary Solvent Mixtures
PublikacjaDapsone is an effective antibacterial drug used to treat a variety of conditions. However, the aqueous solubility of this drug is limited, as is its permeability. This study expands the available solubility data pool for dapsone by measuring its solubility in several pure organic solvents: N-methyl-2-pyrrolidone (CAS: 872-50-4), dimethyl sulfoxide (CAS: 67-68-5), 4-formylmorpholine (CAS: 4394-85-8), tetraethylene pentamine (CAS:...
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Activation Energy and Inclination Magnetic Dipole Influences on Carreau Nanofluid Flowing via Cylindrical Channel with an Infinite Shearing Rate
PublikacjaThe infinite shear viscosity model of Carreau fluid characterizes the attitude of fluid flow at a very high/very low shear rate. This model has the capacity for interpretation of fluid at both extreme levels, and an inclined magnetic dipole in fluid mechanics has its valuable applications such as magnetic drug engineering, cold treatments to destroy tumors, drug targeting, bio preservation, cryosurgery, astrophysics, reaction kinetics,...
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Monitoring of breast tissue thermo-ablation by means of impedance measurements
PublikacjaW pracy przedstawiono rozważania dotyczące monitorowania jakości termoablacji zmian nowotworowych w piersi przy pomocy pomiarów impedancyjnych. Pokazano prototypowe konstrukcje sond do termoablacji jak również zaprezentowano wyniki symulacji i pierwszych eksperymentów. A usefulness of a developed probe combining power delivery to ablated breast tumour and simultaneous impedance measurements is discussed in the paper. It consists...
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PROJECT OF AN TDC SIGNAL DISTRIBUTOR PROTOTYPE WITH GAL-VANIC SEPARATION DESTINED FOR STUDIES OF THE BEGINNING OF SELFIGNITION USING LANGMUIR PROBE
PublikacjaThe knowledge of pistons' TDC is crucial while performing any kind of measurement beneficial to diagnostic inference of a diesel engine. The research of engines under exploitation often cause impartial difficulties with, eg. capability of probe installation. Therefore, it becomes crucial to minimalize those. The paper presents a description of a TDC impulse distributor - divider that provides signal delivery to more than one measurement...
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Analytical procedures for determination of cocaine and its metabolites in biological samples
PublikacjaThe dangerous effects and increased usage of illicit drugs have inspired the development of analytical methodologies. We based our review of analytical procedures for determination of cocaine (COC) and its metabolites on literature from the past two decades. Our main aim was to compare the capabilities of different analytical techniques. The diversity of matrices from which COC is determined (e.g., blood, hair, saliva, plasma,...
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Physical and Mechanical Evaluation of Silicone-Based Double-Layer Adhesive Patch Intended for Keloids and Scar Treatment Therapy
PublikacjaGrowing interest in silicone elastomers for pharmaceutical purposes is due to both theirbeneficial material effect for scar treatment and their potential as drug carriers. Regarding their morphological structure, silicone polymers possess unique properties, which enable a wide range of applicability possibilities. The present study focused on developing a double-layer adhesive silicone film (DLASil) by evaluating its physical...
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A predictive estimation based control strategy for a quasi-resonant dc-link inverter
PublikacjaIn this paper the predictive estimation based control strategy for a quasi-resonant dc link inverter (PQRDCLI) is developed. Instead of direct measurement of dc link input inverter current – its estimation with one step prediction is applied. The PQRDCLI fed induction motor, controlled with a predictive current estimation stabilized inverter output voltage slopes independently of load. Moreover, reduction of overvoltage spikes...
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Ontologiczna inżynieria wiedzy
PublikacjaOntologiczna inżynieria wiedzy jest dobrą podstawą metodologiczną, a ontologie dziedzin przedmiotowych ważnym elementem konstrukcyjnym semantycznych systemów reprezentacji wiedzy. W artykule omówiono budowanie ontologii w oparciu o edytor ontologii FluentEditor i język CNL (Controlled Natural Language). Przykładową ontologię dotyczącą fragmentu procesu produkcji rolniczej wykorzystano do budowy semantycznej bazy wiedzy. W tym celu...
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A testing method of analog parts of mixed-signal electronic systems equipped with the IEEE1149.1 test bus
PublikacjaA new solution of the JTAG BIST for testing analog circuits in mixed-signal electronic microsystems controlled by microcontrollers and equipped with the IEEE1149.1 bus is presented. It is based on a new fault diagnosis method in which an analog circuit is stimulated by a buffered signal from the TMS line, and the time response of the circuit to this signal is sampled by the ADC equipped with the JTAG. The method can be used for...
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Does migration lead to economic convergence in an enlarged European market?
PublikacjaThis paper examines the relationship between migration and convergence for the enlarged internal market of the European Union (EU27) for the period 1990-2007. The impact of migration on growth is estimated in two ways: by including the migration rate in a growth regression and examining its impact on the convergence coefficient; and from the actual coefficient on migration, which can be interpreted as the effect of migration on...
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Measurement of the Development of a Learning IT Organization Supported by a Model of Knowledge Acquisition and Processing
PublikacjaThe paper presents a model of knowledge acquisition and processing for the development of learning organizations. The theory of a learning organization provides neither metrics nor tools to measure its development The authors' studies in this field are based on their experience gathered after projects realized in real IT organizations. The authors have described the construction of the model and the methods of its verification...
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Wireless intelligent audio-video surveillance prototyping system
PublikacjaThe presented system is based on the Virtex6 FPGA and several supporting devices like a fast DDR3 memory, small HD camera, microphone with A/D converter, WiFi radio communication module, etc. The system is controlled by the Linux operating system. The Linux drivers for devices implemented in the system have been prepared. The system has been successfully verified in a H.264 compression accelerator prototype in which the most demanding...
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Towards high quality ITO coatings: the impact of nitrogen admixture in HiPIMS discharges
PublikacjaThe paper reports controlled deposition of optically transparent and electrically conductive ITO films prepared by a combination of rf (13.56 MHz) and High Power Impulse Magnetron Sputtering (HiPIMS) systems without any post deposition thermal treatment/annealing. It is shown that (i) reactive admixture of N2 gas to the process and (ii) pressure in the deposition chamber enable to optimize optical properties of ITO films. Furthermore,...
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Real and imaginary motion classification based on rough set analysis of EEG signals for multimedia applications
PublikacjaRough set-based approach to the classification of EEG signals of real and imaginary motion is presented. The pre-processing and signal parametrization procedures are described, the rough set theory is briefly introduced, and several classification scenarios and parameters selection methods are proposed. Classification results are provided and discussed with their potential utilization for multimedia applications controlled by the...
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Sensorless five-phase induction motor drive with third harmonic injection and inverter output filter
PublikacjaThe paper presents a sensorless control approach for a five-phase induction motor drive with third harmonic injection and inverter output filter. In the case of the third harmonic injection being utilised in the control, the physical machine has to be divided into two virtual machines that are controlled separately and independently. The control system structure is presented in conjunction with speed and rotor flux observers that...
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Prototype and design of six axis robotic manipulator
PublikacjaThe paper presents a design of six axis manipulator. The design consists of specially designed solutions for housing, planetary gearboxes and electronics. The manipulator is controlled by a supervisory control system. The use of a series of measuring elements allows to track the current position of each axis and use this to create a cascade control loop with velocity and acceleration feed-forward. The implemented control algorithm...
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On the use of uniaxial one-parameter damage laws for estimating fatigue life under multiaxial loading
PublikacjaThe goal of this paper is to evaluate the capabilities of different one-parameter fatigue laws to estimate crack initiation in notched components under multiaxial loading. Fatigue damage is accounted for through stress-based, strain-based, and energy-based approaches while the cyclic plasticity at the notch-controlled process zone is estimated using linear-elastic simulations. The results show that energy-based formulations established...
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Direct estimation of linear and nonlinear functionals of quantum state
PublikacjaWe present a simple quantum network, based on the controlled-SWAP gate, that can extract certain properties of quantum states without recourse to quantum tomography. It can be used as a basic building block for direct quantum estimations of both linear and nonlinear functionals of any density operator. The network has many potential applications ranging from purity tests and eigenvalue estimations to direct characterization of...
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Analiza holenderskich doświadczeń w zakresie logistyki miejskiej
PublikacjaW artykule dokonano analizy holenderskich doświadczeń w zakresie logistyki miejskiej i organizacji systemu dostaw towarów na przykładzie Utrechtu. Wybór miasta podyktowany był ponad 20 letnim konsekwentnym zaangażowaniem i doświadczeniem w tej dziedzinie. Przedstawiono zmiany w podejściu do problemów miejskiego transportu ładunków z punktu widzenia polityki krajowej oraz przebieg procesu decentralizacji odpowiedzialności na poziom...
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Mariusz Rutkowski mgr inż.
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Corporate Governance and Ownership Structure in the Top 30 Listed Non Financial Companies in Poland
PublikacjaThis paper offers a first analysis of the relationships between corporate governance models and rules and ownership structure of the top 30 Polish firms listed at the WSE (not considering foreign firms and/or the Polish branches of foreign firms listed at the same stock exchange, nor the financial companies and the banks). The general picture depicted by this analysis is putting into evidence the increasing importance of institutional...
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The geodetic monitoring of the engineering structure – a practical solution of the problem in 3D space
PublikacjaThe study raises the issues concerning the automatic system designed for the monitoring of movement of controlled points, located on the roof covering of the Forest Opera in Sopot. It presents the calculation algorithm proposed by authors. It takes into account the specific design and location of the test object. High forest stand makes it difficult to use distant reference points. Hence the reference points used to study the stability...
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AUTOMATED SYSTEM FOR FLUCTUATION ENHANCED GAS SENSING
PublikacjaResistance gas sensors exhibit random phenomena (resistance noise) which can be utilized to improve gas sensitivity and selectivity. That new emerging technique has to be investigated to recognize optimal parameters for gas detection. It means that a measurement system has to have ability of numerous parameters adjustment (e.g., sampling frequency, heater voltage, polarization current, voltage noise amplification). That fact induced...
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Impact of slow breathing on the blood pressure and subarachnoid space width oscillations in humans
PublikacjaThe aim of the study was to assess cardiac and respiratory blood pressure (BP) and subarachnoid space (SAS) width oscillations during the resting state for slow and fast breathing and breathing against inspiratory resistance. Experiments were performed on a group of 20 healthy volunteers (8 males and 12 females; age 25.3 ± 7.9 years; BMI = 22.1 ± 3.2 kg/m2). BP and heart rate (HR) were measured using continuous finger-pulse photoplethysmography....
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Fast Real-Time RDFT- and GDFT-Based Direct Fault Diagnosis of Induction Motor Drive
PublikacjaThis paper presents the theoretical analysis and experimental verification of a direct fault harmonic identification approach in a converter-fed electric drive for automated diagnosis purposes. On the basis of the analytical model of the proposed real-time direct fault diagnosis, the fault-related harmonic component is calculated using recursive DFT (RDFT) and Goertzel DFT (GDFT), applied instead of the full spectrum calculations...
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Feedback Control of Doubly-Fed Generator Connected to Current Source Converter
PublikacjaDoubly-fed induction generator (DFIG) system supplied by current source converter (CSC) is considered in this article. The DFIG can work in two independent modes: AC grid connection and stand-alone mode. The DFIG is connected to the ac grid directly through its stator and the CSC links the rotor side. In this mode, the active and reactive powers of the DFIG must be controlled. This article proposes two control system structures...
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Development of polyurethanes for bone repair
PublikacjaThe purpose of this paper is to review recent developments on polyurethanes aimed at the design, synthesis, modifications, and biological properties in the field of bone tissue engineering. Different polyurethane systems are presented and discussed in terms of biodegradation, biocompatibility and bioactivity. A comprehensive discussion is provided of the influence of hard to soft segments ratio, catalysts, stiffness and hydrophilicity...
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Molecular dynamics and verisimilitude - to what extent can one trust a computational simulation?
PublikacjaFor the last several tens of years, computer simulations have become of undeniable importance. Molecular Dynamics (MD) simulation techniques are used to examine the phenomena which occur at the level that cannot be observed directly. Thus, they can be successfully exploited in many different scientific fields such as: materials science, applied mathematics and theoretical physics, biochemistry, biophysics or drug design. Despite...
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Novel 1,2,3-Triazole Derivatives as Mimics of Steroidal System—Synthesis, Crystal Structures Determination, Hirshfeld Surfaces Analysis and Molecular Docking
PublikacjaHerein, we present the synthesis and crystal structures determination of five 4-(1-phenyl-1H-1,2,3-triazol-4-yl)phenol derivatives containing halogen atoms, 6a–e, which may be used as an excellent mimic of steroids in the drug development process. Good quality crystals obtained for all of the synthesized compounds allowed the analysis of their molecular structures. Subsequently, the determined crystal structures were used to calculate...
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Experimental verification of visual method for measuring displacements of contact line elements
PublikacjaThe increase of rail vehicles speed, as well as the increase of their power, puts high demands on the power delivery system for traction vehicles The most critical point in the vehicle's power supply circuit is the contact between the current collector and contact wires. Ensuring a reliable co-operation of the current collector and contact line, requires technical development...