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Search results for: NOVEL PSYCHOACTIVE SUBSTANCES
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Determination of antifreeze substances in the airport runoff waters by solid-phase microextraction and gas chromatography–mass spectrometry method
PublicationA new method has been developed for the determination of antifreeze agents such as ethylene glycol (EG), propylene glycol (PG), and diethylene glycol (DEG) in the samples of airport runoff water. The method is based on headspace solid–phase microextraction (HS–SPME) of target analytes, which is coupled with gas chromatography–mass spectrometry (GC–MS). Until now, there was a lack of appropriate methodology for collecting reliable...
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Investigation of sour substances by a set of all-solid-state membrane electrodes
PublicationTestowano elektrody typu all solid state (ASS) w roztworach elektrolitów zawierających substancje o smaku kwaśnym. Elektrody typu ASS zawierają dwa typy membran. Badano wpływ grubości membrany oraz stosunku związek lipofilowy/ chlorek poliwinilu na odpowiedzi elektrod. Stwierdzono, że grubość elektro aktywnego polimeru, nie ma wpływu na czułość i stabilność elektrod w przeciwieństwie do grubości membrany składającej się ze związku...
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Investigation of Taste Substances by five Channel Lipid-Polymer Membrane Sensor.
PublicationBadano substancje o różnych stężeniach należące do czterech klas smaku za pomocą pięcio-kanałowego sensora opartego o elektrody jonoselektywne z różnymi membranami polimerowo-lipidowymi. Stwierdzono, że sensor jest czuły na zmiany stężeń chlorowodorku chininy, kawsu cytrynowego i chlorku sodu, przeciwnie jak w przypadku sacharozy. Na podstawie tych wyników można przypuszczać, że sensor może być zastosowany do roztworów składających...
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On the possibility of molecular recognition of taste substances studied by Gabor analysis of oscillations
PublicationBadano wpływ substancji odpowiedzialnych za wrażenia smakowe należące do czterech klas smaku (słodki, słony, gorzki i kwaśny) na charakterystyki oscylacyjne w nitrometanowym oscylatorze zawierającym kationowy surfaktant: chlorek benzylodimetylotetradecyloamoniowy. Zapropnowano nowe podejście oparte o transformację Gabora za pomocą której otrzymano widma mocy dla posczególnych układów. Wykazano, że dwuwymiarowa forma tych widm może...
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Effect of novel bisacridines (IKE16, IKE18, IKE19, IKE21) and IE10 on the biofilm formation of C. albicans ATCC 10231 cells
Open Research DataThe datasets contain the results of the impact of novel bisacridines (IKE16, IKE18, IKE19, IKE21) and IE10 on the biofilm formation of Candida albicans strain ATCC 10231 cells. Photographic documentation prepared with the TECAN Spark 10M titration plate reader.
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Novel Desorber for Online Drilling Mud Gas Logging
PublicationThis work presents the construction solution and experimental results of a novel desorber for online drilling mud gas logging. The traditional desorbers use mechanical mixing of the liquid to stimulate transfer of hydrocarbons to the gaseous phase that is further analyzed. The presented approach is based on transfer of hydrocarbons from the liquid to the gas bubbles flowing through it and further gas analysis. The desorber was...
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Ahmer Bin Hafeez
PeopleI have experience in Microbiology & Computational Biology, particularly bioinformatics, homology modeling, phylogenetics, structural biology, and drug discovery. Currently, my interest lies in translatable omics studies and drug discovery against novel protein targets involved in cancer and infectious diseases and Host-Pathogen PPIs. My aim involves the use of computational methods for the identification of novel targets and to...
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Cytochromes P-450: specyfic enzymes involved in metabolism of endogenous substances and xenobiotics
PublicationCytochromy P-450 to grupa enzymów hemoproteinowych występujących w prawie wszystkich organizmach żywych. Substratami tych enzymów są zarówno substancje endogenne jak i ksenobiotyki, włączając w to leki, dodatki do żywności oraz zanieczyszczenia środowiska. W pracy omówiono rolę polimorfizmu oraz indukcji P-450 w metabolizmie leków przeciwnowotworowych.
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Properties of PEEK-supported films of biological substances prepared by the Langmuir-Blodgett technique
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Treatment of Mandibular Hypomobility by Injections into the Temporomandibular Joints: A Systematic Review of the Substances Used
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Investigation of some taste substances using a set of electrodes with lipid-modified membranes.
PublicationSkonstruowano 5-cio kanałaowy sensor smaku oparty na elektordach jonoselektywnych z membranami polimerowymi modyfikowanymi lipidem. Badano potencjał elektrod w roztworach kwaśnych zawierających różne stężenie kwasu cytrynowego, solnego i octowego. Sensor jest czuły na stężenia substancji kwaśnych z wyjątkiem kwasu octowego. Testowano nowy typ elektrod zawierających polimer przewodzący PEDT/PSS i kwas oleinowy. Stwierdzono, że...
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The novel sterilization device: the prototype testing
PublicationCurrently, there are numerous methods that can be used to neutralize pathogens (i.e., devices, tools, or protective clothing), but the sterilizing agent must be selected so that it does not damage or change the properties of the material to which it is applied. Dry sterilization with hydrogen peroxide gas (VHP) in combination with UV-C radiation is well described and effective method of sterilization. This paper presents the design,...
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Wojciech Wojnowski dr inż.
PeopleUkończył V Liceum Ogólnokształcące w Gdańsku w klasie o profilu matematyczno-fizycznym z wykładowym językiem angielskim. W 2009 roku rozpoczął studia na Wydziale Chemicznym PG na kierunku technologia chemiczna, uzyskując w 2012 roku tytuł inżyniera, a w 2013 tytuł magistra. W latach 2013–2015 studiował sinologię na Uniwersytecie w Nankinie dzięki uzyskaniu Stypendium Rządu ChRL. Po powrocie do Polski w 2015 roku rozpoczął studia...
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Novel, Fully Biobased Semicrystalline Polyamides
PublicationNovel, semicrystalline polyamides and co(polyamides) were synthesized from biobased sebacic acid (SA), 2,5-diamino-2,5-dideoxy-1,4;3,6-dianhydroiditol (diaminoisoidide, DAII) as well as from 1,4-diaminobutane (DAB), also known as putrescine in nature. Low molecular weight polyamides were obtained by melt polycondensation of the salts based on these monomers or by interfacial polycondensation. In order to increase their molecular...
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Novel 1,2,4-Oxadiazole Derivatives in Drug Discovery
PublicationAbstract: Five-membered 1,2,4-oxadiazole heterocyclic ring has received considerable attention because of its unique bioisosteric properties and an unusually wide spectrum of biological activities. Thus, it is a perfect framework for the novel drug development. After a century since the 1,2,4-oxadiazole have been discovered, the uncommon potential attracted medicinal chemists’ attention, leading to the discovery of a few presently...
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Assessment of toxic and endocrine potential of substances migrating from selected toys and baby products
PublicationAnalysis of literature data shows that there is limited information about the harmful biological effects of mixture of compounds from the EDC group that are released from the surface of toys and objects intended for children and infants. One of the tools that can be used to obtain such information is appropriate bioanalytical tests. The aim of this research involved determining whether tests that use living organisms as an active...
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Sensory Characteristics of Tonic Waters with Various Sweetening Substances vs Young Consumers' Opinion
PublicationThe attitude of young consumers towards food products containing low calorie sweeteners was analyzed as well as consumers’ awareness to the medical recommendations regarding artificial sweeteners. The questionnaire was carried out within the group of 97 respondents at the age of 21 – 30. Strongly negative attitude towards consumption of food products containing low calorie sweeteners was declared by almost half of respondents....
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Green Technology as a Way of Cleaning the Environment from Petroleum Substances in South-Eastern Poland
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New Insights into Dietary Supplements Used in Sport: Active Substances, Pharmacological and Side Effects
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Cooperative response to marine hazardous and noxious substances and oil spill incidents in the ASEAN region
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Language of Benefits as a Novel Tool for Improving Website Personalization
PublicationA properly designed website allows the user to search for information faster, and more accurately. The information content of the website should be also adapted to the needs of the user. The purpose of this article is to present a novel Language of Benefits (LoB) approach to facilitate the use of websites for individual user groups. The LoB approach is an approach addressed to IT Analysts, to facilitate the process of web design,...
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Protonic Ceramic Fuel Cells as novel electrochemical devices
PublicationProton ceramic conductors are novel materials which are interesting from the application point of view. For example, Protonic Ceramic Fuel Cells (PCFCs) is a type of a solid oxide fuel cell, which uses proton ceramic conductors as an electrolyte. Scientists are looking for the most efficient materials for these devices. In recent years main focus has been put on the search for new proton and mixed proton-electron conductors which...
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Dynamic Tests and Technical Monitoring of a Novel Sandwich Footbridge
PublicationA novel sandwich composite footbridge is described in this paper, for the first time after it has been put into operation over the Radunia River in the Pruszcz Gdański municipality. This paper presents results of dynamic tests and describes technical monitoring of the footbridge. The dynamic tests were conducted to estimate pedestrian comfort and were compared with the ones from numerical simulations made in the environment of...
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A novel sensor for measuring temperature profile during the thermoablation
PublicationAbstract — A novel approach for monitoring a temperature distribution inside a tissue during thermoablation is presented in the paper. A thermal profile is measured using a set of serially connected thermistors each bypassed by a capacitor. This technique allows a two-wire and simultaneous multi- point measurements using a multi-frequency measurement of electrical impedance. It is...
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Synthesis and electrochemical characteristics of novel dithiocarbamate polymers
PublicationNovel dithiocarbamate compounds have been obtained by reacting a linear poly(ethylenimine)polymer, MW 50,000, with CS2. The resulting anionic polymers contain, depending on the reaction conditions, up to two sulfur atoms per one nitrogen atom (approx. 40% w/w). The polymers are soluble in dimethylsulfoxide and insoluble in acetonitrile solutions. In both solvents they are electrochemically active, in the latter case as a cast film...
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Toxicity of the New Psychoactive Substance (NPS) Clephedrone (4-Chloromethcathinone, 4-CMC): Prediction of Toxicity Using In Silico Methods for Clinical and Forensic Purposes
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A structure and design of a novel compact UWB MIMO antenna
PublicationIn the paper, a concept and design procedure of a novel compact MIMO slot antenna is presented. In order to achieve a better filling of available space, individual antennas are constrained to a triangular shape and optimized for a reduced size. The MIMO structure is then assembled using the two of previously designed antennas in orthogonal arrangement. Surrogate-assisted numerical optimization involving variable-fidelity electromagnetic...
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Photoelectric properties of a novel MEH-PPV/F16ZnPc heterojunction
PublicationPhotoelectric properties of a novel poly[2-methoxy-5-(2-ethylhexyloxy-p-phenylenevinylen)] (MEH-PPV)/perfluorozincphthalocyanine (F16ZnPc) planar heterojunction provided with BCP and MoO3 buffer layers sandwiched between indium tin oxide (ITO) and Ag are shown. Efficient photogeneration of charge carriers at this junction is observed. Effect of bathocuproine (BCP) and MoO3 buffer layers on the performance of cells is analysed....
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A novel method of time-frequency analysis: an essential spectrogram
PublicationA novel precise method of time-frequency analysis is presented. In the algorithm, a new energy distribution is estimated by simultaneously discard or displacement of the classical spec- trogram energy. A channelized instantaneous frequency and a local group delay are used in order to replacement in the same manner as formulated by Kodera et al. [1, 2]. Additionally, new representations: a channelized instantaneous bandwidth and...
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Treatment of landfill leachate in a constructed free water surface wetland system over a decade – Identification of disturbance in process behaviour and removal of eutrophying substances and organic material
PublicationAn 8 ha free water surface wetland system in Örebro, Sweden, which has sediment traps followed by 10 ponds for treatment of landfill leachate in the methanogenic stage, was studied from 2003 to 2012. The wetland was irregularly loaded and the leachate characteristics showed high temporal and spatial variability, so Multivariate Statistical Process Control was chosen as the diagnostic tool for detecting anomalies prior to assessing...
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Novel single-stage buck-boost inverter with unfolding circuit
PublicationA novel solution of a single-stage buck-boost inverter with unfolding circuit at the output stage is presented. The inverter has a wide range of input voltage regulation, minimum passive components and a very flexible control structure. It can be applied for renewable energy systems where high power density is required. Our simulation results confirmed all theoretical statements
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Inter Applied Chemistry Programme 6 A practical approach to novel industrial enzymes Dr Natasha Bozic
e-Learning CoursesInter Applied Chemistry Programme 6 - A practical approach to novel industrial enzymes Dr Natasha Bozic The purpose of the course is to introduce students to the technologies of industrial enzymes discovery and manufacturing and to provide in depth insight about the advantages of using enzyme preparations in industry. Lectures will cover the common workflows of industrial enzymology including following topics: general enzyme...
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Synthesis and characterization of novel aliphatic polyurethanes for tissue engineering applications
PublicationSummarizing, in this thesis was described the synthesis of novel PUR system, which was obtained by using aliphatic diisocyanate (HDI), amorphous macrodiol (PEBA) and chain extender (BDO). This PUR system was established as suitable for TE purpose and successfully modified with AA, which as expected improved its biocompatibility. According to this, AA-modified HDI-based PURs is the PUR system ready for further studies including...
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Grzegorz Boczkaj dr hab. inż.
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On the new possibility of applying oscillating liquid membrane systems for melecular recognition substances responsible for taste.
PublicationSugerowano wczesniej, że układy osylacyjne z membraną ciekłą mogą być uzyte do opracowania sensora smaku. zbadano wpływ substancji odpowiedzialnych za smak należacych do czterech klas samku na charakterystyki osylacyjne oscylatora z mambrana ciekłą i kationowym surfaktantem chlorkiem benzylodimetylotetradecyloamonionowym. Wykazano,że niezaleznie od natury rozpuszczalnika organicznego w membranie ciekłej charkterystyki oscylacyjne...
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A novel chemiluminescent immunoassay for detection of Toxoplasma gondii IgG in human sera
PublicationThis study describes Toxoplasma gondii IgG chemiluminescent immunoassay (CLIA) based on the use of a novel immunochemical reagents in the form of the conjugates of original acridinium ester (AE) labels attached to antibodies and SAG2-GRA1-ROP1L chimeric antigen and shows that this test is useful for diagnostic purposes.
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Novel structure and design of compact UWB slot antenna
PublicationIn this paper, a novel structure of a compact UWB slot antenna is presented along with a simulation-driven design optimization algorithm for adjusting geometry parameters of the device. Our primary objective is to obtain small footprint of the structure while maintaining its acceptable electrical performance. It is achieved by introducing sufficiently large number of geometry degrees of freedom, including increased number of parameterized...
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Design of novel microstrip directional coupler for differential signal decoupling
PublicationThis study describes a concept of a novel microstrip directional coupler for differential signal decoupling, which can be used to digital signal overhearing on printed-circuit-boards. The complete design method is proposed with rules given analytically. Considered methodology is suitable for synthesis of couplers with low coupling factors, which have negligible influence on the transmission in main line. Theoretical considerations...
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Evaluation of a Novel Approach to Virtual Bass Synthesis Strategy
PublicationThe aim of this paper is to present a novel approach to the Virtual Bass Synthesis (VBS) strategy applied to portable computers. The developed algorithms involve intelligent, rule-based settings of bass synthesis parameters with regard to music genre of an audio excerpt and the type of a portable device in use. The Smart VBS algorithm performs the synthesis based on a nonlinear device (NLD) with artificial controlling synthesis...
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A novel architecture for e-learning knowledge assessment systems
PublicationAbstract. In this paper we propose a novel e-learning system, dedicated strictly to knowledge assessment tasks. In its functioning it utilizes web-based technologies, but its design differs radically from currently popular e-learning solutions which rely mostly on thin-client architecture. Our research proved that such architecture,while well suited for didactic content distribution systems is ill-suited for knowledge assessment...
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A novel architecture for e-learning knowledge assessment systems
PublicationIn this paper we propose a novel e-learning system, dedicated strictly to knowledge assessment tasks. In its functioning it utilizes web-based technologies, but its design differs radically from currently popular e-learning solutions which rely mostly on thin-client architecture. Our research proved that such architecture, while well suited for didactic content distribution systems is ill-suited for knowledge assessment products....
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A novel architecture for e-learning knowledge assessment systems
PublicationIn this paper we propose a novel e-learning system, dedicated strictly to knowledge assessment tasks. In its functioning it utilizes web-based technologies, but its design differs radically from currently popular e-learning solutions which rely mostly on thin-client architecture. Our research proved that such architecture, while well suited for didactic content distribution systems is ill-suited for knowledge assessment products....
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Novel proposal for V2X systems and WBAN cooperation to improve road safety
PublicationIn this paper, a novel proposal of the automotive Vehicle-to-Everything system solution is presented. In this proposal, there are included the Machine to Machine type communication system and the sensor system based on a short-range the Wireless Body Area Network communication. The aim of this paper is the analysis of the model for communication, especially its architecture and signals structure for the proposed solution. The use...
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A novel formulation of 3D spectral element for wave propagation in reinforced concrete
PublicationThe paper deals with numerical simulations of wave propagation in reinforced concrete for damage detection purposes. A novel formulation of a 3D spectral element was proposed. The reinforcement modelled as the truss spectral element was embedded in the 3D solid spectral finite element. Numerical simulations have been conducted on cuboid concrete specimens reinforced with two steel bars. Different degradation models were considered...
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Novel Diazocrowns with Pyrrole Residue as Lead(II) Colorimetric Probes
PublicationNovel 18- and 23-membered diazomacrocycles were obtained with satisfactory yields by diazocoupling of aromatic diamines with pyrrole in reactions carried under high dilution conditions. X-ray structure of macrocycle bearing five carbon atoms linkage was determined and described. Compounds were characterized as chromogenic heavy metal ions receptors. Selective color and spectral response for lead(II) was found in acetonitrile and...
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A novel methodology for the enantiomeric resolution of methamphetamine, its precursors and intermediates by GC-MS
PublicationImpurity profiling and classification of abused drugs using chiral analytical techniques is of particular interest and importance because of the additional information obtained from this approach. When these methods are applied to the synthesis of illicitly used substances, they can supply valuable information about the conditions/chemicals used in the synthesis. In this study, simultaneous chiral separation of methylamphetamine,...
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Quality Evaluation of Novel DTD Algorithm Based on Audio Watermarking
PublicationEcho cancellers typically employ a doubletalk detection (DTD) algorithm in order to keep the adaptive filter from diverging in the presence of near-end speech signal or other disruptive sounds in the microphone signal. A novel doubletalk detection algorithm based on techniques similar to those used for audio signal watermarking was introduced by the authors. The application of the described DTD algorithm within acoustic echo cancellation...
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Development of novel smartphone-based methods of wine quality assessment
PublicationThe doctoral dissertation concerns the development of novel smartphone-based analytical methods of wine quality evaluation, which would be in line with the stipulations of green and equitable analytical chemistry. This solution is based on the analysis of biogenic amines and selected bioactive compounds. The dissertation is based on four articles containing the results of research which led to the development of smartphone-based...
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Assessing therapeutic relevance of biologically interesting, ampholytic substances based on their physicochemical and spectral characteristics with chemometric tools
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Semicrystalline Polyesters Based on a Novel Renewable Building Block
PublicationIsohexides, like e.g. isosorbide, are well-known carbohydrate-based rigid diols which are capable of dramatically increasing the glass transition temperature of polyesters. However, their relatively low reactivity has thus far hampered large-scale industrial applications in the polymer field. Recently, with the aim to increase reactivity while at the same time retain rigidity, we have developed a new isoidide dicarboxylic acid...