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Search results for: human topoisomerase II
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Pojazdy elektryczne - część II
PublicationW drugim tomie książki Pojazdy elektryczne omówiono szczegółowo problematykę hamowania elektrycznych pojazdów szynowych oraz zaprezentowano typy i cechy poszczególnych rodzajów odbieraków prądu.
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In search of molecular precursors for cadmium sulfide-new complexes with a sulfur-rich kernel: cadmium(II) tri-tert-butoxysilanethiolates with additional diethyldithiocarbamato ligand
PublicationW ramach rozprawy opracowano metodę syntezy związków koordynacyjnych kadmu zawierających mieszane ligandy S-donorowe, które stanowią reszta tri-tert-butoksysilanotiolanowa oraz ditiokarbaminianowa. Zostały one poddane badaniom za pomocą analizy składu pierwiastkowego, metod spektroskopowych (FTIR, FIR, UV-Vis, NMR, MS) oraz termicznych. W celu osadzenia cienkich warstw wybranych związków posłużono się techniką nakładania obrotowego...
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Effect of microwave and convection heating on selected nutrients of human milk
PublicationThe aim of this study was to determine the influence of the microwave heating method (MWH) on selected determinants of the nutritional value of human milk (HM) and compare to the effect exerted by the standard convection heating (CH) method, including holder pasteurization (HoP). It was showed that using MWH under conditions assumed to ensure microbiological safety, changes in the level of the nutrients were not observed. In these...
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CD99 correlates with low cyclin D1, high topoisomerase 2 status and triple negative molecular phenotype but is prognostically irrelevant in breast carcinoma
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Reducing nighttime light exposure in the urban environment to benefit human health and society
PublicationNocturnal light pollution can have profound effects on humans and other organisms. Recent research indicates that nighttime outdoor lighting is increasing rapidly. Evidence from controlled laboratory studies demonstrates that nocturnal light exposure can strain the visual system, disrupt circadian physiology, suppress melatonin secretion, and impair sleep. There is a growing body of work pointing to adverse effects of outdoor lighting...
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Tymieniecka's conception of ''the moral sence''in the life of the human person
PublicationW artykule, pt. "Tymieniecka's Conception of "the Moral Sense" in the Life of the Human Person" ("Tymienieckiej koncepcja "moralnego sensu" w życiu ludzkiej osoby") pokazałem, że koncepcja ta przybliża nas do znaczącego novum, którym jest zmysł moralny. Następnie pokazałem, że filozofka odkrywa jego obecność w oszacowującym procesie ze strony osoby ludzkiej. Z kolei uwypukliłem znaczenie "doświadczenia...
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Blood equivalent phantom vs whole human blood, a comparative study
PublicationPreclinical research of biomedical optoelectronic devices is often performed with the use of blood phantoms — a simpli¯ed physical model of blood. The aim of this study is the comparison and distinction between blood phantoms as well as whole human blood measurements. We show how the use of such phantoms may in°uence the incorrect interpretation of measured signal. On the other hand, we highlight how the use of blood phantoms enables...
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Widma elektronowe kompleksów miedzi(II) z imidazolem w ciele stałym i w roztworze
PublicationZsyntetyzowano szereg związków kompleksowych miedzi(II) z ligandami chlorkowymi i różnymi alkilowymi pochodnymi imidazolu: 4(5) metyloimidazolem, 2-etyloimidazolem, 2-izopropyloimidazolem i 2-etylo-4-metyloimidazolem. Otrzymane głównie kompleksy jednordzeniowe oraz jeden kompleks dwurdzeniowy (z 2-etyloimidazolem). Zbadano widma elektronowe otrzymanych kompleksów w roztworach metanolowych i porównano je z widmami otrzymanymi z...
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Genetic programming extension to APF-based monocular human body pose estimation
PublicationNew method of the human body pose estimation based on a single camera 2D observation is presented, aimed at smart surveillance related video analysis and action recognition. It employs 3D model of the human body, and genetic algorithm combined with annealed particle filter for searching the global optimum of model state, best matching the object's 2D observation. Additionally, new motion cost metric is employed, considering current...
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N,N’-Bis(salicylidene)ethylenediamine (Salen) as an Active Compound for the Recovery of Ni(II), Cu(II), and Zn(II) Ions from Aqueous Solutions
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Colloidal transport of lipid digesta in human and porcine small intestinal mucus
PublicationSmall intestinal mucus transport of food-derived particulates has not been extensively studied, despite mucus being a barrier nutrients need to cross before absorption. We used complex dispersions of digesta obtained from simulated, dynamic gastrointestinal digestion of yogurt to examine the penetrability of human and porcine mucus to the particles formed of lipolysis products. Quantitative, time-lapse confocal microscopy revealed...
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Dissecting gamma frequency activities during human memory processing
PublicationGamma frequency activity (30-150 Hz) is induced in cognitive tasks and is thought to reflect underlying neural processes. Gamma frequency activity can be recorded directly from the human brain using intracranial electrodes implanted in patients undergoing treatment for drug-resistant epilepsy. Previous studies have independently explored narrowband oscillations in the local field potential and broadband power increases. It is not...
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Thermal analysis of manganese(II) complexes of general formula (Bu4N)2[MnBrnCl4−n]
PublicationBadano termiczną dekompozycję związków zawierających aniony tetrahalogenomanganese(II), [MnBrnCl4−n]2−(n = 0-4) i kationy tetrabutylammonium. Stosowane metody to: DSC, TG-FTIR, TG-MS i DTA. Pomiary prowadzono w argonie i powietrzu w zakresie temperatur 173-450K (DSC) i 300-1073K (TG). Stałe produkty dekompozycji identyfikowano metodami spektroskopii FT-FIR i dyfraktometrii rentgenowskiej.
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High frequency oscillations are associated with cognitive processing in human recognition memory
PublicationHigh frequency oscillations are associated with normal brain function, but also increasingly recognized as potential biomarkers of the epileptogenic brain. Their role in human cognition has been predominantly studied in classical gamma frequencies (30-100 Hz), which reflect neuronal network coordination involved in attention, learning and memory. Invasive brain recordings in animals and humans demonstrate that physiological oscillations...
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Thermostability and photophysical properties of mixed-ligand carboxylate/benzimidazole Zn(II)-coordination polymers
PublicationThe reaction between Zn(NO3)2*6H2O or Zn(CH3COO)2*2H2O and isophthalic acid (1,3-H2bdc) in the presence of benzimidazole (Hbzim) in dimethylformamide (DMF)/ethanol (EtOH)/H2O solvent mixture at room temperature yielded two structurally different coordination polymers: [Zn2(1,3-bdc)2(Hbzim)2] (1) and [Zn2(1,3-bdc)(bzim)2] (2). (1) is a 2D-layered framework with a molecule of benzimidazole coordinated to the Zn center, whereas (2)...
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Serum trace elements in animal models and human depression: Part III. Magnesium. Relationship with copper
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Application of 3D Whole Body Scanning in Research on Human Body Surface Area
PublicationHuman body surface area (BSA) is one of the major parameters used in several medical fields. Its heterogeneity caused by individual human characteristics sustains a many-decades-long research on the matter. Today’s technology allows to create exact body models in mere seconds. However, an extensive research that includes scanning people with major disfigurements or people suffering from diseases, which often prevent their mobility,...
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Studies of the effects of antifungal cationic derivatives of amphotericin B on human erythrocytes.
PublicationBadano nową grupę kationowych pochodnych amfoterycyny B pod kątem zależności pomiędzy ich zdolnością do asocjacji i selektywną toksycznością. We wszystkich przypadkach stosowano amfoterycynę B jako związek odniesienia. Jako miarę efektu toksycznego in vitro badanych związków stosowano wypływ wewnątrzkomórkowego potasu oraz hemolizę. Miarą aktywności przeciwgrzybowej był MIC i utrata potasu wewnatrzkomórkowego. Do oceny stopnia...
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Physicochemical and Biological Properties of Oxovanadium(IV), Cobalt(II) and Nickel(II) Complexes with Oxydiacetate Anions
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Complexes of manganese(II) tri-tert-butoxysilanethiolate with chelating N-donor ligands.
PublicationTri-tert-butoksysilanotiolan manganu(II) jest związkiem wrażliwym i rozkładającym się w warunkach atmosferycznych. Z tego względu synteza jego pochodnych z chelatującymi zasadami heterocyklicznymi takimi jak 1,10-fenantrolinaza czy 2,2'-bipirydyl wydawał się dogodną metodą otrzymania bardziej stabilnych układów. Otrzymane w ten sposób krystaliczne proszki wykazują znacznie wyższą stabilność temperaturową, możliwe jest więc przechowywanie...
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Synteza i badania strukturalne związków kompleksowych miedzi(I) i rtęci(II) z wybranymi ligandami tioamidowymi
PublicationPrzedstawiona rozprawa doktorska poświęcona jest związkom tiokarbonylowym (wybranym tioamidom i tiomocznikom) oraz ich połączeniom kompleksowym z halogenkami miedzi(I) i rtęci(II). Istota i cel takich badań przedstawione są we wstępie pracy. W części teoretycznej opisane zostały kluczowe pierwiastki wchodzące w skład syntezowanych związków kompleksowych (siarka, miedź i rtęć), jak również tioamidy i tiomoczniki. Szczególna uwaga...
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Osady denne, ściekowe i przemysłowe. II Ogólnopolska Konferencja Naukowo-Techniczna ''Gospodarka osadami OSAD2006''
PublicationPrzedstawiono relację z II Ogólnopolskiej Konferencji Naukowo-Technicznej ''Gospodarka osadami OSAD2006'', która uwzględniała problematykę osadów, od mechanizmów powstawania osadów do rozwiązań procesowych ich zagospodarowania lub unieszkodliwiania.
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π-Stacking attraction vs. electrostatic repulsion: competing supramolecular interactions in a tpphz-bridged Ru(ii)/Au(iii) complex
PublicationThe synthesis and characterization of a mixed metal ruthenium(II)/gold(III) complex bridged by tetrapyridophenazine (tpphz) are described. It is isostructural and isoelectronic to the well-known photocatalysts with palladium(II) or platinum(II). Concentration dependent 1H-NMR spectroscopy and XRD studies show that the electrostatic repulsion between the gold(III) moieties exceeds the attractive π-stacking interaction. Theoretical...
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New sample preparation strategies for comprehensive lipidomics of human breast milk
PublicationGLOBAL PROFILING ANALYSIS OF HUMAN BREAST MILK (HBM) LIPIDS IS HINDERED BY COMPLEX COMPOSITION OF HBM. THIS PROBLEM IS HUGE FROM ANALYTICAL POINT OF VIEW, SINCE DUE TO THAT DETECTION OF ALL HBM LIPIDS DURING ONE ANALYTICAL RUN IS LIMITED. THUS, SAMPLE PREPARATION STEP CONSTITUTES A CRUCIAL STEP IN UNTARGETED LIPIDOMIC ANALYSIS OF HBM, ESPECIALLY WHEN SEMI-QUANTITATIVE ANALYSIS IS ASSUMED. HEREIN, WE PRESENT A COMPARISON OF PUBLISHED...
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In vivo imaging of the human eye using a two-photon excited fluorescence scanning laser ophthalmoscope
PublicationBACKGROUND. Noninvasive assessment of metabolic processes that sustain regeneration of human retinal visual pigments (visual cycle) is essential to improve ophthalmic diagnostics and to accelerate development of new treatments to counter retinal diseases. Fluorescent vitamin A derivatives, which are the chemical intermediates of these processes, are highly sensitive to UV light; thus, safe analyses of these processes in humans...
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Raport z II etapu badań eksperymentalnych żelbetowych płyt prefabrykowanych z łącznikami balkonowymi
PublicationNiniejsze opracowanie stanowi raport z II etapu badań prefabrykowanych zestawów balkonowych o wymiarach (szerokość × długość × wysokość): 2,0 m × 2,78 m × 0,186 m (w spadku do 0,17 m) składających się z żelbetowych płyt połączonych ze sobą łącznikami balkonowymi typu 1 lub typu 2.
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A novel in vivo approach to assess strains of the human abdominal wall under known intraabdominal pressure
PublicationThe study concerns mechanical behaviour of a living human abdominal wall. A better mechanical understanding of a human abdominal wall and recognition of its material properties is required to find mechanically compatible surgical meshes to significantly improve the treatment of ventral hernias. A non-invasive methodology, based on in vivo optical measurements is proposed to determine strains of abdominal wall corresponding to...
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Influence of accelerometer signal pre-processing and classification method on human activity recognition
PublicationA study of data pre-processing influence on accelerometer-based human activity recognition algorithms is presented. The frequency band used to filter-out the accelerometer signals and the number of accelerometers involved were considered in terms of their influence on the recognition accuracy. In the test four methods of classification were used: support vector machine, decision trees, neural network, k-nearest neighbor.
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High frequency oscillations in human memory and cognition: a neurophysiological substrate of engrams?
PublicationDespite advances in understanding the cellular and molecular processes underlying memory and cognition, and recent successful modulation of cognitive performance in brain disorders, the neurophysiological mechanisms remain underexplored. High frequency oscillations beyond the classic electroencephalogram spectrum have emerged as a potential neural correlate of fundamental cognitive processes. High frequency oscillations are detected...
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Synteza i właściwości warstw poli(3,4-etylenodioksytiofenu) modyfikowanego heksacyjanożelazianami (II/III) wybranych metali przejściowych
PublicationPraca dotyczy modyfikacji warstw polimeru elektroatywnego poli(3,4-etylenodioksytiofenu) heksacyjanożelazianami (II/III) wybranych metali przejściowych (Fe, Co, Ni).
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Vitamin D and Human Health
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The Evolutionary Concept of Human Death
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Human emotion recognition with biosignals
PublicationThis chapter presents issues in the field of affective computing. Basic preliminary information for the recognition of emotions is given and models of emotions, various ways of evoking emotions, as well as their theoretical foundations are discussed. The particular attention is given to the use of physiological signals in recognizing emotions. This subject is outlined further below by presenting selected biosignals, their relationship...
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Analysis of human behavioral patterns
PublicationWidespread usage of Internet and mobile devices entailed growing requirements concerning security which in turn brought about development of biometric methods. However, a specially designed biometric system may infer more about users than just verifying their identity. Proper analysis of users’ characteristics may also tell much about their skills, preferences, feelings. This chapter presents biometric methods applied in several...
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Histogram of Oriented Gradients with Cell Average Brightness for Human Detection
PublicationA modification of the descriptor in a human detector using Histogram of Oriented Gradients (HOG) and Support Vector Machine (SVM) is presented. The proposed modification requires inserting the values of average cell brightness resulting in the increase of the descriptor length from 3780 to 3908 values, but it is easy to compute and instantly gives ≈ 25% improvement of the miss rate at 10‒4 False Positives Per Window (FPPW). The...
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Influence of Escherichia coli on Expression of Selected Human Drug Addiction Genes
PublicationThe impact of enteric microflora on the expression of genes associated with cocaine and amphetamine addiction was described. Human genome-wide experiments on RNA transcripts expressed in response to three selected Escherichia coli strains allowed for significant alteration (p > 0.05) of the linear regression model between HT-29 RNA transcripts associated with the KEGG pathway:hsa05030:Cocaine addiction after 3 h stimulation with...
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Struktury fotowoltaiczne z planarnym heterozłączem półprzewodnik II-VI / półprzewodnik molekularny
PublicationArtykuł przedstawia wybrane wyniki badań własnych nad układami hybrydowymi zbudowanymi na bazie złącza półprzewodnik nieorganiczny II-VI/półprzewodnik organiczny. Na podstawie analizy położenia pasm energetycznych warstw wchodzących w skład wytworzonych ogniw oraz charakterystyk spektralnych prądu zwarcia tych urządzeń określone zostały procesy prowadzące do fotogeneracji nośników ładunku w badanych układach. W ogniwach zbudowanych...
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Determination of thiocyanate as a biomarker of tobacco smoke constituents in selected biological materials of human origin
Publicationn order to protect human health, it is necessary to biomonitor toxic substances originating from tobacco smoke in biological materials sampled from persons with different exposures to tobacco smoke constituents. Thiocyanate anion is a biomarker of exposure to tobacco smoke components which is characterized by a relatively long half‐life in the human body, i.e. 6 days. In this work, we present the results of thiocyanate determinations...
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Analysis of the enthalpies of transfer of Co(II) ion in mixed solvents by means of the theory of preferential solvation.
PublicationZa pomocą teorii solwatacji preferencyjnej zanalizowano entalpie przeniesienia jonu Co(II) w kilku mieszaninach wodno-organicznych i organicznych, wyznaczając parametry, które w sposób ilościowy opisują solwatację preferencyjną jonu i jego wpływ na oddziaływania między cząsteczkami rozpuszczalnika. Przeprowadzono porównanie właściwości solwatacyjnych mieszanin. Wyznaczono także średni skład sfery solwatacyjnej jonu w zależności...
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Climate Change Impacts on Environmental and Human Exposure to Mercury in the Arctic
PublicationThis paper reviews information from the literature and the EU ArcRisk project to assess whether climate change results in an increase or decrease in exposure to mercury (Hg) in the Arctic, and if this in turn will impact the risks related to its harmful effects. It presents the state-of-the art of knowledge on atmospheric mercury emissions from anthropogenic sources worldwide, the long-range transport to the Arctic, and it discusses...
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Investigation of photothermolysis therapy of human skin diseases using optical phantoms
PublicationDermatological diseases, such as neurofibroma (Recklinghausen disease) or hemangiomas can be efficiently treated using photothermolysis from laser irradiation. We have utilized a developed 975 nm fiber diode laser as a low-cost alternative over common Nd:YAG lasers. This paper describes the investigations of interaction of 975 nm diode laser radiation-pulses with optical skin phantoms which were designed and manufactured in our...
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The X-ray crystallographic structures, spectral and magnetic properties of nickel(II), copper(II) and cobalt(II) complexes with tetra(3-iso-propylpyrazol-1-yl)borate
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Hierarchical Estimation of Human Upper Body Based on 2D Observation Utilizing Evolutionary Programming and 'Genetic Memory'
PublicationNew method of the human body pose estimation based on single camera 2D observation is presented. It employs 3D model of the human body, and genetic algorithm combined with annealed particle filter for searching the global optimum of model state, best matching the object's 2D observation. Additionally, motion cost metric is employed, considering current pose and history of the body movement, favouring the estimates with the lowest...
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Chemistry of human breast milk – a comprehensive review of the composition and role of milk metabolites in child development
PublicationEarly nutrition has an enormous influence on a child's physiological function, immune system maturation and cognitive development. Human breast milk (HBM) is recognized as the gold standard for human infant nutrition. Accordingly to WHO report breastfeeding is consider as an unequalled way of providing ideal food to the infant, which is required for his healthy growth and development. HBM contains various macronutrients (carbohydrates,...
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HUMAN & EXPERIMENTAL TOXICOLOGY
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Managing safety of industrial hazardous installations with emphasis on the control systems, interfaces and human factors
PublicationIn the paper a procedure for the layer of protection analysis (LOPA) as a tool to evaluate the risk of accident scenarios occurrence in hazardous installations is outlined. In such installations several protection layers exist. Human operator performance in each layer is unavoidable, but the role and tasks are different and depend on the context of situation. Based on suggestions form literature (EEMUA, CREAM) and own proposals...
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Can high hydrostatic pressure processing be the best way to preserve human milk?
PublicationBreastfeeding is one of the most important factors influencing proper child development. When a mother cannot breastfeed, the best alternative, especially for feeding premature infants, is to then use of human milk (HM) which has been collected, preserved and stored in Human Milk Banks (HMB). Scope and approach: In this review, the impact of some stages of the management of HM in HMB on its final biological value and microbiological...
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Beneficial effects and potential risks of tomato consumption for human health: An overview
PublicationTomato and its derived products have a very interesting nutritional value in addition to prominent antioxidant,anti-inflammatory, and anticancer activities. In terms of tomatoes are generally quite safe to eat. However,overall consumption varies from individual to individual. Indeed, either beneficial or harmful effects of plantsor their derived products are closely related to quality, including the presence of biologically active...
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Technologie recyklingu zużytych i odpadowych modułów fotowoltaicznych I i II generacji
PublicationW związku z rosnącą produkcją modułów fotowoltaicznych i faktem, że czas życia pierwszych montowanych modułów dobiega końca w najbliższej przyszłości na wysypiskach będą zalegać duże ilości zużytych modułów fotowoltaicznych. Odzysk metali z uszkodzonych i zużytych modułów pozwoliłby na obniżenie kosztu produkcji ogniw, oraz na ograniczenie zużycia surowców. I generacja obejmuje moduły wykonane z mono- i polikrystalicznego krzemu,...
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Toxoplasma gondii recombinant antigens as tools for serodiagnosis of human toxoplasmosis: current status of studies
PublicationToxoplasma gondii is a parasitic protozoan which is the cause of toxoplasmosis. Although human toxoplasmosis in healthy adults is usually asymptomatic, serious disease can occur in the case of congenital infections and immunocompromised individuals. Furthermore, despite the exact recognition of its etiology, it still presents a diagnostic problem. Diagnosis of toxoplasmosis is mainly based on the results of serological tests detecting...