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The biological role of prolyl oligopeptidase and the procognitive potential of its peptidic inhibitors from food proteins
PublicationProlyl oligopeptidase (POP) is a conserved serine protease belonging to proline-specific peptidases. It has both enzymatic and non-enzymatic activity and is involved in numerous biological processes in the human body, playing a role in e.g., cellular growth and differentiation, inflammation, as well as the development of some neurodegenerative and neuropsychiatric disorders. This article describes the physiological and pathological...
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Geo-Questionnaire for Environmental Planning: The Case of Ecosystem Services Delivered by Trees in Poland
PublicationStudies on society and the environment interface are often based on simple questionnaires that do not allow for an in-depth analysis. Research conducted with geo-questionnaires is an increasingly common method. However, even if data collected via a geo-questionnaire are available, the shared databases provide limited information due to personal data protection. In the article, we present open databases that overcome those limitations....
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Shear Cap Size Selection Method Based on Parametric Analysis of ACI-318 Code and Eurocode 2 Standard
PublicationThe scope of the paper is to propose a method for determining the size of shear caps in a slab–column-connections-reinforced concrete structure. Usually, shear heads are used to enhance slab–column connection, especially when the transverse reinforcement does not give the required punching shear load capacity. The dimensions of the shear head should provide the punching shear resistance of the connection inside and outside the...
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Airfoil Design Under Uncertainty Using Non-Intrusive Polynomial Chaos Theory and Utility Functions
PublicationFast and accurate airfoil design under uncertainty using non-intrusive polynomial chaos (NIPC) expansions and utility functions is proposed. The NIPC expansions provide a means to efficiently and accurately compute statistical information for a given set of input variables with associated probability distribution. Utility functions provide a way to rigorously formulate the design problem. In this work, these two methods are integrated...
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Zastosowanie technik dwuwymiarowych w analizie frakcji lotnej i oznaczaniu związków bioaktywynych owoców jagody kamczackiej
PublicationDotychczasowe doniesienia literaturowe wskazują, że owoce strefy borealnej, do których należy popularna w Polsce aronia, są źródłem cennych składników odżywczych i prozdrowotnych. Podobnie jagoda kamczacka, należąca do tej grupy owoców, może stanowić źródło substancji istotnych dla ludzkiej diety. Jednakże aktualny stan wiedzy o składzie chemicznym owoców jagody kamczackiej ogranicza się głównie do informacji dotyczących całkowitej...
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Equitable colorings of some variation of corona products of cubic graphs
PublicationThe problem of determining the value of equitable chromatic number for multicoronas of cubic graphs is studied. We provide some polynomially solvable cases of cubical multicoronas and give simple linear time algorithms for equitable coloring of such graphs which use almost optimal number of colors in the remaining cases.
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Navigating the complexities of altruistic helping in Nonprofit Organizations: An analysis of Benefits, Burdens and managerial challenges
PublicationWe investigate how individuals cope with side effects of altruistic behaviour at work, i.e. genuine helping behaviour which is not part of any job description, and what role the organizational context plays in these dynamics. Employing simultaneous dyadic interviews, we show how employees of non-profit organizations cope with undesired effects of altruistic help. Our data provides evidence of unintended outcomes for the individual...
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Asymmetric Renyi Problem and > PATRICIA Tries
PublicationIn 1960 R´enyi asked for the number of random queries necessary to recover a hidden bijective labeling of n distinct objects. In each query one selects a random subset of labels and asks, what is the set of objects that have theselabels? Weconsider here anasymmetric version of the problem in which in every query an object is chosenwith probability p > 1/2 and we ignore “inconclusive” queries. We study the number of queries needed...
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Method of lines for physiologically structured models with diffusion
PublicationWe deal with a size-structured model with diffusion. Partial differential equations are approximated by a large system of ordinary differential equations. Due to a maximum principle for this approximation method its solutions preserve positivity and boundedness. We formulate theorems on stability of the method of lines and provide suitable numerical experiments.
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Roof over PGE Arena in Gdansk. Review of structure and monitoring system
PublicationThis paper presents general structural assumptions of the steel construction designed for a newfootball stadium to be built for UEFA Championship 2012 in the city of Gdańsk. The superstructureis founded directly on the modified abutment. The facade and the roof are collected from 82 steelgirders made of tube profiles. The girders are braced by circular beams and X tension rods. All thiscreates a quasi - dome covered by polycarbonate...
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Experimental investigation of M-shape heat transfer coefficient distribution of R123 flow boiling in small-diameter tubes
PublicationW publikacji przedstawiono wyniki badań wrzenia czynnika R123 w srebrnych rurkach o małych średnicach (średnice wewnętrzne wynosiły odpowiednio 1.15 mm i 2.3 mm). Badania przeprowadzono w szerokim zakresie stopnia suchości pary (0.01-0.9), gęstości strumienia masy (650-3000 kg/(m2s)) oraz gęstości strumienia ciepła (40-80 kW/m2). W badaniach wykazano, że istnieją dwa lokalne maksima współczynnika przejmowania ciepła w jego profilu...
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Assessment of atmospheric inorganic pollution in the urban region of Gdańsk, Northern Poland
PublicationProjekt wykonano w przemysłowej części Gdańska w celu zidentyfikowania głównych źródeł zanieczyszczeń. Próbki suchego oraz żywego (w hodowli hydroponicznej) mchu eksponowano równolegle w celu określenia ich właściwości kumulacji w aspekcie badań biomonitoringowych. Analizę chemiczną składu próbek mchu wykonano dzięki zastosowaniu techniki aktywacji neutronowej i reaktorze badawczym w Delft (Holandia). Uzyskane wyniki wskazują,...
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Thickness monitoring of thin lamellae by optical measurement method
PublicationDo dnia dziesiejszego do pomiaru grubosci tarcicy używa się głównie suwmiarek. Celem projektu było opracowanie skanera, nie wymagajacego wysokich nakładów finansowych, do pomiarów grubości lameli po operacji rozpiłowywania drewna. Opracowany system jest zdolny do wykrywania elementów odbiegajacych od okreslonych tolerancji wymiarowych. zastosowano metodę pomiaru typu sandwich wykorzystująca 4 głowice laserowe. Wyazano, że przy...
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Stability of cylindrical steel silos composed of corrugated sheets and columns based on FE analyses versus Eurocode 3 approach
PublicationComprehensive static and dynamic 3D stability finite element analyses of a cylindrical steel silo composed of corrugated sheets and open thin-walled vertical stiffener profiles were carried out by taking the geometric and material non-linearity into account. The silowas subjected to axisymmetric and non-axisymmetric loads imposed by a bulk solid following Eurocode 1. Theoretical and measured initial geometric imperfections were...
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INTENSYFIKACJA WYMIANY CIEPŁA W WYMIENNIKU WĘŻOWNICOWYM Z WYKORZYSTANIEM PRZEGRÓD O RÓŻNEJ GEOMETRII
PublicationW pracy zaprezentowano możliwości wykorzystania pasywnej intensyfikacji wymiany ciepła w postaci przegród dla podniesienia efektywności energetycznej wymiennika wężownicowego. Badania zostały przeprowadzone z wykorzystaniem modułowego wymiennika z wężownicą w postaci grzałki elektrycznej. Medium odbierającym ciepło była woda o stałych parametrach cieplnoprzepływowych na wlocie do modułu. Pomiary przeprowadzono dla szerokiego zakresu...
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Analiza symulacyjna wybranych algorytmów dostarczania paczek wiadomości w sieci DTN na Bałtyku
PublicationJedną z dróg zwiększania bezpieczeństwa żeglugi morskiej jest zapewnienie powszechnej dostępności usług e-nawigacji na obszarach morskich pozbawionych dostępu do Internetu. W artykule opisano wyniki symulacji wybranych algorytmów przekazywania wiadomości usług niewrażliwych na opóźnienia w znacznej odległości od lądu, w sieci o nieciągłej i sporadycznej łączności.
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Knowledge Societies Policy Handbook
PublicationThe Handbook builds upon existing knowledge and practices to provide policy-makers with an actionable conceptual framework for understanding and assessing the relationships between the Sustainable Development Goals and Knowledge Societies. By identifying gaps as well as strengths, the Handbook will enable countries to more effectively deploy resources and implement appropriate policy measures.
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Seismic response and performance prediction of steel buckling-restrained braced frames using machine-learning methods
PublicationNowadays, Buckling-Restrained Brace Frames (BRBFs) have been used as lateral force-resisting systems for low-, to mid-rise buildings. Residual Interstory Drift (RID) of BRBFs plays a key role in deciding to retrofit buildings after seismic excitation; however, existing formulas have limitations and cannot effectively help civil engineers, e.g., FEMA P-58, which is a conservative estimation method. Therefore, there is a need to...
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Modeling and simulation of blood flow under the influence of radioactive materials having slip with MHD and nonlinear mixed convection
PublicationRadioactive materials are widely in industry, nuclear plants and medical treatments. Scientists and workers in these fields are mostly exposed to such materials, and adverse effects on blood and temperature profiles are observed. In this regard, objective of the current study is to model and simulate blood based nanofluid with three very important radioactive materials, named as Uranium dioxide (UO2), Thorium dioxide (ThO2) and...
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Long‐time scale simulations of virus‐like particles from three human‐norovirus strains
PublicationThe dynamics of the virus like particles (VLPs) corresponding to the GII.4 Houston, GII.2 SMV, and GI.1 Norwalk strains of human noroviruses (HuNoV) that cause gastroenteritis was investigated by means of long-time (about 30 μs in the laboratory timescale) molecular dynamics simulations with the coarse-grained UNRES force field. The main motion of VLP units turned out to be the bending at the junction between the P1 subdomain (that...
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Cloud solutions as a platform for building advanced learning platform, that stimulate the real work environment for project managers
PublicationImproving skills of managers and executives require, that during the transfer of knowledge (in different ways: during studies, trainings, workshops and other forms of education) it is necessary to use tools and solutions that are (or will be) used in real world environments, where people being educated are working or will work. Cloud solutions allow educational entities (universities, training companies, trainers, etc.) to provide...
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A Self-Equalized Waveguide Filter With Frequency-Dependent (Resonant) Couplings
PublicationThis letter presents a design of a fifth-order linear phase filter with frequency-dependent couplings. The filter is composed of a triplet that is directly coupled to two resonators at the input and output. To provide group delay flattening a cross-coupling in the trisection has a strongly dispersive character with a negative slope parameter. To achieve this, an E-plane stub with a septum was used. To further improve the filter...
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Assessment of under power ed propulsion machinery in electrically driven small inland waterway passenger ships from classification society point of view
PublicationPaper presents short operat ional a nd engineering analysis of underpowered propulsion in small electrically propelled small inland passenger ships. There is evidence that in certain weather conditions the phenomena of added aerodynamic resistance of small water crafts may have seriou s influence on their speed and manoeuvrability. Existing regulations like class societies rules for ship classification and construction or EU Directive 2006/87/EC do...
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Integrating web site services into application through user interface
PublicationThe issue of integrating applications which are only accessible through visual user interface is not thoroughly researched. Integration of web applications running remotely and controlled by separate organizations becomes even more complicated, as their user interface can display differently in different browsers or change without prior notification as a result of application maintenance. While possible, it is generally not common...
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ASSESSMENT OF UNDERPOWER ED PROPULSION MACHINERY IN ELECTRICALLY DRIVEN SMALL INLAND WATERWAY PASSENGER SHIPS FROM CLASSIFICATION SOCIETY POINT OF View
PublicationPaper presents short operat ional a nd engineering analysis of underpowered propulsion in small electrically propelled small inland passenger ships. There is evidence that in certain weather conditions the phenomena of added aerodynamic resistance of small water crafts may have serious influence on their speed and manoeuvrability. Existing regulations like class societies rules for ship classification and construction or EU Directive 2006/87/EC do...
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Exploring Relationships Between Data in Enterprise Information Systems by Analysis of Log Contents
PublicationEnterprise systems are inherently complex and maintaining their full, up-to-date overview poses a serious challenge to the enterprise architects’ teams. This problem encourages the search for automated means of discovering knowledge about such systems. An important aspect of this knowledge is understanding the data that are processed by applications and their relationships. In our previous work, we used application logs of an enterprise...
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Analyzing Preconditions to Introduce Internet Voting in Portugal: Insights from the Estonian Model
PublicationInternet voting has been trialed or introduced for several countries, including Norway, Portugal, United States, United Kingdom and Switzerland as an additional voting channel to increase voter turnout and, also to modernize the electoral process. However, only Estonia has successful introduced internet voting, deploying e-enabled elections in general governmental levels. This paper aims to provide an exploratory study on the Estonian...
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Zero-Visibility Cops and Robber Game on a Graph
PublicationWe examine the zero-visibility cops and robber graph searching model, which differs from the classical cops & robber game in one way: the robber is invisible. We show that this model is not monotonic. We also provide bounds on both the zero-visibility copnumber and monotonic zero-visibility copnumber in terms of the pathwidth.
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Silence/noise detection for speech and music signals
PublicationThis paper introduces a novel off-line algorithm for silence/noise detection in noisy signals. The main concept of the proposed algorithm is to provide noise patterns for further signals processing i.e. noise reduction for speech enhancement. The algorithm is based on frequency domain characteristics of signals. The examples of different types of noisy signals are presented.
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The Impact of Information and Communication Technology on the Rise of Urban Social Movements in Poland
PublicationThe chapter examines the relationship between the use of Information and Communications Technology (ITC) and the emergence of social movements focused on urban agenda in Poland. The aim is to investigate how and to what extent a growing body of smaller activist groups use opportunities provided by the ITC to achieve their political objectives. The research results indicate that Web-based media have helped to raise the profile...
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The Impact of Information and Communications Technology on the Rise of Urban Social Movements in Poland
PublicationThe chapter examines the relationship between the use of Information and Communications Technology (ITC) and the emergence of social movements focused on urban agenda in Poland. The aim is to investigate how and to what extent a growing body of smaller activist groups use opportunities provided by the ITC to achieve their political objectives. The research results indicate that Web-based media have helped to raise the profile of...
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Innovative cold-formed GEB section under compression
PublicationCold-formed steel sections extensively affect the modern steel construction industry. Not only are they used as secondary elements like purlins or sheeting, but also they can serve as primary load-bearing members in fabricated steel panels and trusses. A new cross-section called shortly a GEB may serve as that member. However, its existence of the metal building structures industry depends on the exact, optimal dimensional parameters...
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Conception for diagnosing SI engines fed with biofuel in operation conditions
PublicationThe article deals with the question of diagnosing the high power self ignition (SI) engines fed with pro-ecologic fuels in an aspect of appearing operation problems. There has been presented the specific of action and techno-operation profile of the combustion engine foreseen as an investigations object. The preliminary conception of diagnostic investigations of the engine 7L35MC type produced in H. Cegielski - Poznan S.A. factory...
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Towards β-selectivity in functional estrogen receptor antagonists
PublicationBased on the benzo[b]naphtho[1,2-d]furan and benzo[b]naphtho[1,2-d]thiophene frameworks, a series of ligands with different basic side chains (BSCs) has been synthesized and pharmacologically evaluated. Also, their binding modes have been modelled using docking techniques. It was found that the introduction of a BSC in these systems brings about a decrease of affinity for both estrogen receptors α and β in an in vitro competitive...
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Health-Promoting Effects of Ethylene-Treated Kiwifruit ‘Hayward’ from Conventional and Organic Crops in Rats Fed an Atherogenic Diet
PublicationKiwifruit is a subtropical fruit that is very popular among consumers. Kiwifruit ‘Hayward’ (Actinidia deliciosa C.F. Liang et A.R. Ferguson) is an important source of bioactive compounds and possesses high antioxidant capacity, but its value can be changed during ripening. The aim of this study was to compare the levels of total polyphenols (TP), ascorbic acid (AA), and total antioxidant capacities (TACs) of ethylene-treated and...
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Specific Binding of Cholesterol to the Amyloid Precursor Protein: Structure of the Complex and Driving Forces Characterized in Molecular Detail
PublicationC99 is the C-terminal membrane-bound fragment of the amyloid precursor protein that is cleaved by γ-secretase to release Aβ peptides, the hallmark of Alzheimer’s disease (AD). Specific interactions of C99 with cholesterol have been proposed to underlie the recognized role of cholesterol in promoting amyloidogenesis. By using molecular dynamics simulations, we studied cholesterol binding to C99 in a lipid bilayer. We determined...
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Selected aspects of the surface quality of the wooden elements after planing
PublicationThe quality of the surface of wooden elements, that have been planed, has got a crucial meaning in the whole production process flow, since the obtained effects affect the quality of wooden surface after painting. The emergence of defects in most cases causes need to qualify workpiece as a scrap part or additional work activity must be done. In the paper selected results of the investigation of the effect of the cutting tool wear...
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Topography measurement methods evaluation for entire bending-fatigued fracture surfaces of specimens obtained by explosive welding
PublicationIn this paper, the methods of compensation of differences in the results of entire bending-fatigued fracture surface topographies were presented. The roughness evaluation was performed with a focus variation microscope and confocal surface topography measurement techniques. The differences in the ISO 25178 roughness parameters were investigated and procedures for their compensation were studied. It was found that various types...
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The impact of cold plasma on the phenolic composition and biogenic amine content of red wine
PublicationThe effect of cold plasma (CP) on phenolic compound (PC) and biogenic amine (BA) contents of red wine was investigated for the first time. The influence of CP was compared with the effects of a wine preservation using potassium metabisulfite and a combined method. The PC profile was determined by UPLC-PDA-MS/MS while BAs using DLLME-GC–MS. Chemometric analysis also was used. The content of PCs was 3.1% higher in the sample preserved...
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Roughness evaluation of turned composite surfaces by analysis of the shape of Autocorrelation Function
PublicationIn this paper, the application of an Autocorrelation Function for the characterisation of surface topography was validated. The roughness evaluation of turned composite surfaces was supported by sophisticated studies of the Autocorrelation Function properties, considering especially the shape of the function. Details were measured with the optical method. The selection of the surface roughness evaluation procedures was carried...
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Active Power Quality Controllers
PublicationDynamic Static Synchronous Compensator is the most important controller for distribution networks and probably in SEEN. It has been widely used since the 1990s to regulate system voltage precisely, improve voltage profile, reduce voltage harmonics, reduce transient voltage disturbances and load compensation. Rather than using conventional capacitors and inductors combined with fast switches, the D-STATCOM uses a power-electronics...
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Improvement of opipramol base solubility by complexation with β-cyclodextrin
PublicationOpipramol (OPI), a tricyclic antidepressant and anxiolytic compound, is administered orally in the form of a dihydrochloride. Salt form of the drug has a higher solubility in water and hence bioavailability and stability. A similar effect can be achieved by closing the hydrophobic part of the drug molecule in the cyclodextrin cavity. The paper presents opipramol inclusion complexes with beta-cyclodextrin (β-CD) in 1:1 molar ratio....
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The Influence of the Co-Dopant Dexamethasone Phosphate on the Electrodeposition Process and Drug-Release Properties of Polypyrrole-Salicylate on Iron
PublicationIn this work, the influence of incorporation of two anti-inflammatory drugs dexamethasone phosphate and sodium salicylate on the electrodeposition process of polypyrrole (PPy) film on iron has been studied. The incorporation of the agents into PPy has been carried out in a one-step electropolymerization process on oxidizable iron. The role of each drug agent during the deposition process has been discussed. The morphological and...
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Theoretical and Economic Evaluation of Low-Cost Deep Eutectic Solvents for Effective Biogas Upgrading to Bio-Methane
PublicationThis paper presents the theoretical screening of 23 low-cost deep eutectic solvents (DESs) as absorbents for effective removal of the main impurities from biogas streams using a conductor-like screening model for real solvents (COSMO-RS). Based on thermodynamic parameters, i.e., the activity coefficient, excess enthalpy, and Henry’s constant, two DESs composed of choline chloride: urea in a 1:2 molar ratio (ChCl:U 1:2), and choline...
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Numerical Study on Seismic Response of a High-Rise RC Irregular Residential Building Considering Soil-Structure Interaction
PublicationThe objective of the present study is to investigate the importance of soilstructure interaction effects on the seismic response of a high-rise irregular reinforced-concrete residential building. In order to conduct this research, a detailed three-dimensional structure model was subjected to various earthquake excitations, also including a strong mining tremor. Soil-foundation flexibility was represented using the spring-based...
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Drainage and capillary rise components in water balance of alluvial soils
PublicationPrzepływ wody przez dolny brzeg profilu glebowego stanowi ważny element wielu modeli pracy drenażu. Przeciekanie wody w głąb albo podsiąk kapilarny ku górze mierzone były metodą lizymetryczną w warunkach polowych podczas 4 lat (1972-1975). Podsiąk kapilarny wynosił 40-50% ogólnego zasilania w wodę w glebach typu Histosols, natomiast prawie zero w glebach typu Inceptisols. Pomierzone wartości pozwalaja na ocenę wymiany wody pomiedzy...
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Social development and ICT adoption. Recent evidence from developing world
PublicationThis paper is designed to provide empirical evidence on the relationship between the process of ICT diffusion and social development across selected low-income and lowermiddle- income countries during the period of 2000 and 2014. It main target it so identify whether in low-income and lower-middle-income economies, ICT development and social development (social empowerment) are correlated.
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THE INFLUENCE OF QUESTION SET ON STUDENT QUIZ RESULTS
PublicationThe advent of e-Learning tools allowing for automated online test grading will probably increase the frequency of using tests in technical education. The same tools may provide for measures of test question quality. By purposely crafting question sets, test grading may serve different goals. The paper contains examples and test study with score histograms.
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Metals in the environment as risk factors for infectious diseases: gaps and opportunities
PublicationThis chapter aims to provide insights into current knowledge and gaps in our understanding of the influence that trace metals in the environment have on the pathogenesis of infectious diseases. By reducing immune function, trace metal deficiencies may substantially contribute to the global burden of diarhea, pneumonia, and malaria. Improved methods and biomarkers for assessing the risk of trace metals deficiencies and toxicities...
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Supporting First Year Students Through Blended-Learning - Planning Effective Courses and Learner Support
PublicationHigher education has been actively encouraged to find more effective and flaxible delivery models to provide all students with access to good quality learning experiences. This paper describes students opinion about using e-learning techniques and their participation in courses provided in different ways as additional help and expectations of first year students.