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Search results for: INVERSE AGONIST
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Hysteresis modelling of a medium frequency single-phase transformer
PublicationThe article describes a feedback Preisach hysteresis model equivalent circuit implementation of a medium frequency single-phase transformer being a part of a high power and high efficiency DC-DC converter. The macroscopic models of magnetic hysteresis are introduced and the feedback Preisach model is selected for further analysis. The hysteresis model is developed for a prototype transformer and the hysteresis loops are compared...
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Some problems of slide bearing material fatigue evaluation.
PublicationA slide bearing alloy resistance against fatigue failures have been investigated for three different lubricants, different heat loadings and different stress ratio κ values. The research methods and data handling procedures for determination of particular parameter effects on fatigue strength have been described and analysed for experiments that were set and performed in laboratory tester SKMR-2. Main and interaction effects of...
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Empirical analysis of tree-based classification models for customer churn prediction
PublicationCustomer churn is a vital and reoccurring problem facing most business industries, particularly the telecommunications industry. Considering the fierce competition among telecommunications firms and the high expenses of attracting and gaining new subscribers, keeping existing loyal subscribers becomes crucial. Early prediction of disgruntled subscribers can assist telecommunications firms in identifying the reasons for churn and...
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Rhythm and Colours of the Angles
PublicationABSTRACT The game of space was and still is a crucial aspect of visual arts. The aim of this study is to examine how the arrangement of hues, rhythms and angles of various polygons can create an impression of depth and movement on a flat surface. The so-called Penrose tiling and Ulam's spiral are mathematical models that have been applied for the painting experiment. There is a vast amount of evidence gathered over the ages that...
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The Immunogenic and Immunoprotective Activities of Recombinant Chimeric T. gondii Proteins Containing AMA1 Antigen Fragments
PublicationToxoplasmosis, one of the most common parasitoses worldwide, is potentially dangerous for individuals with a weakened immune system, but specific immunoprophylaxis intended for humans is still lacking. Thus, efforts have been made to create an efficient universal vaccine for both animals and humans to overcome the shortcomings of currently used treatment methods and protect all hosts against toxoplasmosis. The current work represents...
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The Effect of Conjugation with Octaarginine, a Cell-Penetrating Peptide on Antifungal Activity of Imidazoacridinone Derivative
PublicationAcridine cell-penetrating peptide conjugates are an extremely important family of compounds in antitumor chemotherapy. These conjugates are not so widely analysed in antimicrobial therapy, although bioactive peptides could be used as nanocarriers to smuggle antimicrobial compounds. An octaarginine conjugate of an imidazoacridinone derivative (Compound 1-R8) synthetized by us exhibited high antifungal activity against reference...
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The Influence of Antitumor Unsymmetrical Bisacridines on 3D Cancer Spheroids Growth and Viability
PublicationThe culture of 3D spheroids is a promising tool in drug development and testing. Recently, we synthesized a new group of compounds, unsymmetrical bisacridines (UAs), which exhibit high cytotoxicity against various human cell lines and antitumor potency against several xenografts. Here, we describe the ability of four UAs—C-2028, C-2041, C-2045, and C-2053—to influence the growth of HCT116 and H460 spheres and the viability of HCT116...
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The Synergistic Microbiological Effects of Industrial Produced Packaging Polyethylene Films Incorporated with Zinc Nanoparticles
PublicationZinc compounds in polyolefin films regulate the transmission of UV-VIS radiation, affect mechanical properties and antimicrobial activity. According to hypothesis, the use of zinc- containing masterbatches in polyethylene films (PE) with different chemical nature—hydrophilic zinc oxide (ZO) and hydrophobic zinc stearate (ZS)—can cause a synergistic effect, especially due to their antimicrobial properties. PE films obtained on an...
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Improvement of glass break acoustic signal detection via application of wavelet packet decomposition
PublicationThe main subject of the authors' research are non-contact methods of glass break detection based on analysis of the acoustic signal generated during the event. This problem has essential meaning for modern cost- effective alarm systems, particularly those installed into big buildings. The main difficulties of the matter are: transient character of the signal, great number of similar sounds (false signals, mainly accidental glass...
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KONCEPCJA DWU-ŚMIGŁOWEJ ELEKTROWNI WIATROWEJ I ELEKTROWNI SZCZYTOWO-POMPOWEJ NA WZGÓRZU SZUBIENICZNYM
PublicationDogodne warunki terenowe Wzgórza Szubienicznego w Gdańsku oraz istniejąca tam infrastruktura stanowią podstawę do rozważenia koncepcji doposażenia instalacji badawczej Laboratorium Innowacyjnych Technologii Elektroenergetycznych i Integracji Odnawialnych Źródeł Energii LINTE^2 w skojarzony, hydro-wiatrowy zespół wytwórczy. W artykule zaproponowano koncepcję budowy elektrowni pompowo-szczytowej z turbinami Francisa oraz elektrowni...
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Metodyka projektowania i eksploatacji dróg szynowych z wykorzystaniem mobilnych pomiarów satelitarnych
PublicationW pracy zostały przedstawione aplikacyjne możliwości metody mobilnych pomiarów satelitarnych w projektowaniu i eksploatacji dróg szynowych. Pokazano wizualizację położenia toru kolejowego, omówiono sposoby oceny odcinków prostych toru i odcinków położonych w łuku oraz tworzenie poligonu kierunków głównych trasy. Szczególną uwagę poświęcono opracowanej analitycznej metodzie projektowania, omawiając jej algorytmy obliczeniowe: projektowania...
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Sektorowe zróżnicowanie płynności finansowej przed-siębiorstw
PublicationPłynność finansowa warunkuje prawidłowość funkcjonowania całej firmy. Uzależniona jest od niej możliwość przetrwania przedsiębiorstwa na rynku oraz perspektywa jego rozwoju. Artykuł podejmuje tematykę zróżnicowania płynności finansowej przedsiębiorstw w zależności od ich przynależności sek-torowej. Z przeprowadzonych badań wynika, że wartość wskaźników z obsza-ru płynności finansowej jest silnie zróżnicowana w przekroju sektorowym....
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Particle Shape Effect on Macroscopic Behaviour of Underground Structures: Numerical and Experimental Study
PublicationThe mechanical performance of underground flexible structures such as buried pipes or culverts made of plastics depend not only on the properties of the structure, but also the material surrounding it. Flexible drains can deflect by 30% with the joints staying tight, or even invert. Large deformations of the structure are difficult to model in the framework of Finite Element Method, but straightforward in Discrete Element Methods....
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Particle Shape Effect on Macroscopic Behaviour of Underground Structures: Numerical and Experimental Study
PublicationAbstract: The mechanical performance of underground flexible structures such as buried pipes or culverts made of plastics depend not only on the properties of the structure, but also on the material surrounding it. Flexible drains can deflect by 30% with the joints staying tight, or even invert. Large deformations of the structure are difficult to model in the framework of Finite Element Method, but straightforward in Discrete...
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Kod fontannowy z przyrastającą liczbą symboli źródłowych
PublicationKody fontannowe zabezpieczające transmisję przed wymazaniami wyróżnia brak określonej z góry długości i losowy sposób generacji kolejnych pakietów kodowych. W pracy pokazano jak właściwości tych kodów zależą od rozkładu macierzy generującej dla dwóch wariantów dostarczania pakietów do kodera. Szczególnie interesujący jest przypadek, gdy pakiety źródłowe trafiają do kodera stopniowo podczas transmisji. Uzyskane wyniki wskazują na...
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Resonant and nonresonant excitation of waves in a planar magnetosonic flow
PublicationForced propagation of perturbations in a magnetosonic wave are considered. The driving force may be caused by stimulated Mandelstam–Brillouin scattering of optic waves or by intense magnetosonic exciter. Some heating-cooling function which takes into account radiative cooling and unspecified heating is taken into consideration, as well as nonlinearity of a medium. Both these factors make the excitation particular. The analytical...
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Inorganic membrane: a game changer for gas separation and purification
PublicationThis review explores the advancements and remaining challenges in inorganic membrane science, particularly focusing on their potential for industrial applications. It delves into the fundamental principles of inorganic membrane design, fabrication, and characterization techniques. The review also critically analyzes key challenges faced by inorganic membranes, such as physical aging, plasticization, defective formation, and fouling....
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Efficient Use of Capital: Paradox of Real Estate and Industry in Turkey
PublicationIn recent years, one of the hottest debates on Turkish economy is the conflict on resource allocation between real estate and industry sectors. The debate was so intense that ex-minister of Economy Mr. Ali Babacan declared his opinions. Mr. Babacan’s statements about the creation of fixed capital by the private sector is not promising, and private sector fixed capital expenditures are not in the desired level. This situation is...
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THE EFFECT OF DRYING INTENSITY ON THE COLOR CHANGES OF PINE WOOD (PINUS SYLVESTRIS L.)
PublicationThe effect of the selection of drying process parameters on the color change of Scots pine wood (Pinus Sylvestris L.) is presented. In this work the experimental studies have been performed. The research focused on the influence of drying intensity on the changes of color after drying process. Intensity of drying process was determined on the basis of the average drying gradient. To determine the color of wood before and after...
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Adaptive Optimal Discrete-Time Output-Feedback Using an Internal Model Principle and Adaptive Dynamic Programming
PublicationIn order to address the output feedback issue for linear discrete-time systems, this work suggests a brand-new adaptive dynamic programming (ADP) technique based on the internal model principle (IMP). The proposed method, termed as IMP-ADP, does not require complete state feedback, merely the measurement of input and output data. More specifically, based on the IMP, the output control problem can first be converted into a stabilization...
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Own or public? Later livelihoods of Ukrainian war migrant households in Poland
PublicationThis paper presents empirical research on the livelihood resources of Ukrainian households that fled to Poland due to the Russian invasion and reside there long term. Using a nationwide sample of these households and an accurate econometric framework, we investigate the factors influencing the role of income from work, other private resources and public assistance in covering their living costs in exile. Our findings confirm the...
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About definition of modes and magnetosonic heating in a plasma’s flow: Especial cases of perpendicular and nearly perpendicular wave vector and magnetic field
PublicationDynamics of hydrodynamic perturbations in a plasma depend strongly on an angle between the wave vector and equilibrium straight magnetic field. The case of perpendicular propagation is especial. There are only two (fast) magnetosonic modes since two (slow) ones degenerate into the stationary one with zero speed of propagation. This demands individual definition of wave modes by the links of hydrodynamic relations. These links are...
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How Swiss Watchmaking Brands are Communicating Made in Switzerland
PublicationCountry-of-origin indications, also called “made in” labeling [35], are utilized in marketing strategies by companies to distinguish themselves from others, trying to associate their products with positive characteristics [9]. Swiss watchmaking companies have an iconic status that is essential to their reputation - mainly due to their high quality, precision, innovation, and craftsmanship [7]. They are also using country-of-origin...
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Shielded HMSIW-Based Self-Triplexing Antenna With High Isolation for WiFi/WLAN/ISM Band
PublicationThis article presents a novel design of a miniaturized self-triplexing antenna (STA) based on the shielded half-mode substrate integrated waveguide (S-HMSIW) for WiFi/WLAN/ISM-band applications. The S-HMSIW is constructed by assembling one row of vias and an open slot at the open-ended side of the conventional HMSIW. This configuration increases the quality factor and minimizes unwanted radiation loss, which allows for achieving...
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Induction Generator with Direct Control and a Limited Number of Measurements on the Side of the Converter Connected to the Power Grid
PublicationThe article presents an induction generator connected to the power grid using the AC/DC/AC converter and LCL coupling filter. Three-level inverters were used in the converter, both from the generator side and the power grid side. The algorithm realizing Pulse Width Modulation (PWM) in inverters has been simplified to the maximum. Control of the induction generator was based on the Direct Field-Oriented Control (DFOC) method. At...
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Recent Advances in Nanocomposite Membranes for Organic Compound Remediation from Potable Waters
PublicationWater treatment is one of the main approaches for producing drinking water from contaminated water sources which is challenging due to the presence of a variety of substances requiring removal. The fabrication of nanocomposite membranes relies either on filling nanomaterials into polymeric phases before membrane fabrication, or coating of nanomaterials on the fabricated membrane surface. The removal of organic compounds from potable...
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Organic Vapor Sensing Mechanisms by Large-Area Graphene Back-Gated Field-Effect Transistors under UV Irradiation
PublicationThe gas sensing properties of graphene back-gated field-effect transistor (GFET) sensors toward acetonitrile, tetrahydrofuran, and chloroform vapors were investigated with the focus on unfolding possible gas detection mechanisms. The FET configuration of the sensor device enabled gate voltage tuning for enhanced measurements of changes in DC electrical characteristics. Electrical measurements were combined with a fluctuation-enhanced...
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INFORMATION ABOUT DYNAMICS OF THE SEA SURFACE AS A MEANS TO IMPROVE SAFETY OF THE UNMANNED VESSEL AT SEA
PublicationOne of the fundamental states of the sea surface is its heave. Despite of years of the intense scientific inquiry, no clear understanding of the influence of this aspect on the dynamics of the sea environment has emerged. The separation of two nearby fluid elements which one may observed for example as a free floating of small objects on the sea surface (rescuers on the rough sea or small research vessels) is caused by the interaction...
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Bilateral multi-issue negotiation of execution contexts by proactive document agents
PublicationA proactive document can react to its actual environment by autonomously selecting and performing actions integrated into its body and interact with its user. When migrating over a network of execution devices it may encounter diverse execution contexts, each one set up according to temporal characteristics of a receiving device and preferences of its owner. A concept to augment proactive documents with negotiation capability is...
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The Touristification of Italian Historic City Centres: The Lesson for Central Europe about the Airbnb Eruption
PublicationThe unparalleled scale of the recent growth in tourism – the rise of the number of temporary visitors – could not have emerged without the impact on other socio‑economic aspects, namely, a change on the part of the destinations. Especially historic city centres are vulnerable to such an impact that could be manifested through diverse transformations of public space usage, housing market economics, availability of services, employment...
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Study on applicability of two modal identification techniques in irrelevant cases
PublicationStudy on applicability of two modal identification techniques in irrelevant cases is made in this paper. The following techniques are considered: Peak Picking based on correlation analysis (PP-CA), dedicated for ambient vibrations and Eigensystem Realization Algorithm (ERA), formulated for free decay vibrations investigation. Irrelevant cases are found when analyzed signals are different than recommended to a given technique. The...
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Numerical Study on Seismic Response of a High-Rise RC Irregular Residential Building Considering Soil-Structure Interaction
PublicationThe objective of the present study is to investigate the importance of soilstructure interaction effects on the seismic response of a high-rise irregular reinforced-concrete residential building. In order to conduct this research, a detailed three-dimensional structure model was subjected to various earthquake excitations, also including a strong mining tremor. Soil-foundation flexibility was represented using the spring-based...
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On the Dynamics of a Visco–Piezo–Flexoelectric Nanobeam
PublicationThe fundamental motivation of this research is to investigate the effect of flexoelectricity on a piezoelectric nanobeam for the first time involving internal viscoelasticity. To date, the effect of flexoelectricity on the mechanical behavior of nanobeams has been investigated extensively under various physical and environmental conditions. However, this effect as an internal property of materials has not been studied when the...
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Linkages between services and manufacturing as a new channel for GVC growth: evidence from CEE countries
PublicationThe aim of this paper is to use a panel Granger causality test to verify the hypothesis of the existence of a causal relationship between forward linkages from domestic services to manufacturing and a country’s participation and position in GVCs in selected central and eastern European economies – the Czech Republic, Estonia, Hungary, Latvia, Lithuania, Poland and Slovakia – for the period 2000-2014. Our results show that the Baltic...
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Buzz-based recognition of the honeybee colony circadian rhythm
PublicationHoneybees are one of the highly valued pollinators. Their work as individuals is appreciated for crops pollination and honey production. It is believed that work of an entire bee colony is intense and almost continuous. The goal of the work presented in this paper is identification of bees circadian rhythm with a use of sound-based analysis. In our research as a source of information on bee colony we use their buzz that have been...
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Various cases of preservation and adaptive reuse Heritage Buildings in the Port of Gdynia
PublicationThe port of Gdynia contains a diverse range of heritage assets, starting with its spatial layout which is an urban concept designed in the first half of the 1920s. It is important to point out, this historically-shaped harbor space is preserved in its general idea and still functioning in port activities. Another significant element is the structural, technological solution which was the basis for constructing the entire port area...
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Determination of pesticide residues in fruits and vegetables using QuEChERS sample preparation method
PublicationThe intensive development of agriculture means that more and more toxic organic and inorganic compounds are entering the environment. Because of their widespread use, environmental stability, selective toxicity and bioaccumulative capability, pesticides belong to the most hazardous substances contaminating the environment. They are particularly dangerous in fruits and vegetables, because they are one of the reasons why people are...
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Determination of Butyltin Species in Sea Water Samples Using Solid Phase Extraction Followed by Liquid Chromatography - Tandem Mass Spectrometry
PublicationReverse phase liquid chromatography (RP-HPLC)-electrospray ionization-tandem mass spectrometry (ESI-MS-MS) was evaluated for the analysis of TBT using solid phase extraction as sample preparation method. TBT was extracted from acidified water samples (spiked with tripropyltin as internal standard) using reversed phase polymeric Strata-X cartridges. Analytes were eluted from cartridges using acetonitrile-water mixture and the volume...
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Evaluation of excessive noise effects on hearing employing psychoacoustic dosimetry
PublicationResearch results regarding the noise impact on hearing applying the concept of the Psychoacoustic Noise Dosimetry (PND) are presented. The general characteristics of the PND algorithm are discussed. Additionally, the results of hearing examinations conducted in the laboratory conditions are shown. The main objective of the research was to determine the time needed for the Temporary Threshold Shift to reverse. The results were used...
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Municipal wastewater reclamation: Reclaimed water for hydrogen production by electrolysis – A case study
PublicationThis paper presents an analysis of a treatment system selection for municipal wastewater stream based on the DuPont Water Solutions WAVE software. The results obtained based on an analysis of 7 different processing cases studies (ultrafiltration and reverse osmosis) confirmed that the application of 2-pass membrane systems enables the reclamation of water from municipal wastewater that fulfills the requirements concerning the...
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Acoustic heating produced in the thermoviscous flow of a Bingham plastic
PublicationThis study is devoted to the instantaneous acoustic heating of a Bingham plastic. The model of the Bingham plastic's viscous stress tensor includes the yield stress along with the shear viscosity, which differentiates a Bingham plastic from a viscous Newtonian fluid. A special linear combination of the conservation equations in differential form makes it possible to reduce all acoustic terms in the linear part of of the final equation...
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A Triplet-Learnt Coarse-to-Fine Reranking for Vehicle Re-identification
PublicationVehicle re-identification refers to the task of matching the same query vehicle across non-overlapping cameras and diverse viewpoints. Research interest on the field emerged with intelligent transportation systems and the necessity for public security maintenance. Compared to person, vehicle re-identification is more intricate, facing the challenges of lower intra-class and higher inter-class similarities. Motivated by deep...
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Acoustic heating produced in the thermoviscous flow of a bingham plastic
PublicationThis study is devoted to the instantaneous acoustic heating of a Bingham plastic. The model of the Bingham plastic's viscous stress tensor includes the yield stress along with the shear viscosity, which differentiates a Bingham plastic from a viscous Newtonian fluid. A special linear combination of the conservation equations in differential form makes it possible to reduce all acoustic terms in the linear part of of the final equation...
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Direct brain stimulation modulates encoding states and memory performance in humans
PublicationPeople often forget information because they fail to effectively encode it. Here, we test the hypothesis that targeted electrical stimulation can modulate neural encoding states and subsequent memory outcomes. Using recordings from neurosurgical epilepsy patients with intracranially implanted electrodes, we trained multivariate classifiers to discriminate spectral activity during learning that predicted remembering from forgetting,...
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Identification of the mechanical properties of the skin by electromechanical impedance analysis of resonant piezoelectric actuator
PublicationThis paper is devoted to the analysis and verification of developed piezoelectric sensor/actuator for measuring the mechanical properties of soft tissues, especially human skin. The key element of the measurement structure is an electromechanical system that uses both the reverse piezoelectric effect (vibration generation – stimulation of the tissues in the appropriate frequency range) and direct piezoelectric effect (system response...
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Globalisation and world economic poverty: The significance of hidden dimensions
PublicationThe aim of our research is to examine how individual dimensions of globalization affect economic poverty in the World. for this, regression models are estimated with FGT0 or FGT1 poverty measures as dependent variables and KOF indices of globalization as despendent variables. The poverty indices are estimated for 119 countries' income didtributions assuming log-normality and using Gini estimates from the WID2 database and GDP/capita...
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SENSITIVITY OF PUBLIC PLACES IN GDAŃSK OSOWA DISTRICT
PublicationThis paper summarises the results of the research carried out at the University of Ljubljana, Faculty of Architecture, Slovenia, during the PhD visiting period of the first author from the Gdansk University of Technology, Poland, in the framework of the PhD course "Sensitive urban places", leaded by the second author. Focusing to the specific problems of the Gdansk Osowa district in Poland, this research develops the idea of sensitivity...
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Potencjał strategii slow city dla rozwoju miast kształtujących się metropolii polskich. Na przykładzie Pucka i Kartuz miast Obszaru Metropolitalnego Gdańsk-Sopot-Gdynia
PublicationW artykule wskazano możliwości wykorzystania filozofii ruchu Slow, do wykształcenia nowego modelu Metropolitalnych Slow City (MSC). Odniesiono się do założeń ruchu Cittaslow, pokazując potencjały dla alternatywnego kierunku strategii rozwojowej w duchu „miast dobrego życia” dla ośrodków w granicach obszarów metropolitalnych. W podsumowaniu założenia teoretyczne zilustrowano przykładem innowacyjnego modelu projektu rewitalizacji...
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Fatty acids as molecular carriers in cleavable antifungal conjugates
PublicationConjugates composed of C2-18 fatty acid (FA) residues as a molecular carrier and 5-fluorocytosine (5-FC) as an active agent, released upon the action of intracellular esterases on the ester bond between FA and “trimethyl lock” intramolecular linker, demonstrate good in vitro activity against human pathogenic yeasts of Candida spp. The minimal inhibitory concentrations (MIC) values for the most active conjugates containing caprylic...
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On the problem of optimised allocation of water quality sensors and actuators in DWDS
PublicationThe problems of water quality sensors and actuators placement in drinking water distribution systems (DWDSs) are addressed as separate, primarily. However, against the background of control systems theory, the nature of DWDSs dynamics indicates that these both problems are interdependent and impact the design of related water quality monitoring and control structures and algorithms. The research work presented in this paper is...