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Search results for: glutathione-gated potassium efflux (ggke)
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An Intelligent Approach to Short-Term Wind Power Prediction Using Deep Neural Networks
PublicationIn this paper, an intelligent approach to the Short-Term Wind Power Prediction (STWPP) problem is considered, with the use of various types of Deep Neural Networks (DNNs). The impact of the prediction time horizon length on accuracy, and the influence of temperature on prediction effectiveness have been analyzed. Three types of DNNs have been implemented and tested, including: CNN (Convolutional Neural Networks), GRU (Gated Recurrent...
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Justifying the prolongation of the service life of the bearing structure of a tank car when using Y25 bogies
PublicationThis paper substantiates the use of Y25 bogies under tank cars in order to prolong their service life. The reported study has been carried out for a tank car with rated parameters, as well as the actual ones, registered during full-scale research. Mathematical modeling was performed to determine the basic indicators of the tank car dynamics. The differential equations of motion were solved by a Runge-Kutta method using the Mathcad...
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Antifungal dipeptides incorporating an inhibitor of homoserine dehydrogenase
PublicationThe antifungal activity of 5‐hydroxy‐4‐oxo‐L‐norvaline (HONV), exhibited under conditions mimicking human serum, may be improved upon incorporation of this amino acid into a dipeptide structure. Several HONV‐containing dipeptides inhibited growth of human pathogenic yeasts of the Candida genus in the RPMI‐1640 medium, with minimal inhibitory concentration values in the 32 to 64 μg mL−1 range. This activity was not affected by multidrug...
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ACTIVATED BIOCHAR AS AN ADSORBENT OF ORGANIC POLLUTANTS FOR WATER AND WASTEWATER TREATMENT
PublicationThe use of biomass, especially waste biomass, as an alternative energy source is a very important issue today. Pyrolysis is a process of thermal degradation of raw material and one of its products is biochar. This product is mainly distinguished by its high carbon content, and by improving its quality through activation, it can be more widely used. Activated biocarbon has a strongly developed surface and porous structure, and as...
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A comparative study on the decolorization of Tartrazine, Ponceau 4R, and Coomassie Brilliant Blue using persulfate and hydrogen peroxide based Advanced Oxidation Processes combined with Hydrodynamic Cavitation
PublicationDecolorization of Ponceau 4R, Tartrazine, and Coomassie Brilliant Blue (CBB) was studied using hybrid processes of hydrodynamic cavitation (HC) with potassium persulfate (KPS) and hydrogen peroxide (H2O2). The different properties of these dyes such as hydrophobicity, molecular structures, and molecular weights provided this opportunity to investigate the effects of these factors by comparing the decolorization values of the dyes....
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Optimization of electrochemical doping approach resulting in highly photoactive iodine-doped titania nanotubes
PublicationThe paper focuses on the optimization procedure concerning the synthesis method resulting in highly ordered titania nanotubes doped with iodine atoms. The doping process was based on the electrochemical treatment of a titania nanotube layer immersed in a potassium iodide (KI) solution acting as an iodine precursor. A number of endeavors were undertaken in order to optimize the doping conditions. Electrolyte concentration, reaction...
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Interoperability Description of Web Services Based Application Servers
PublicationWeb services standards were designed to enable interoperability of heterogeneous application servers in the Service Oriented Architecture. Although the standards proved to be highly successful, there are still difficulties in effective services integration. The paper presents a methodology that enables description of application servers interoperability in order to improve the service integration process. The methodology proposes...
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Multi-pulse VSC arrangements with coupled reactors
PublicationThis paper presents a novel approach to the multipulse VSC (Voltage Source Converter) arrangements based on several conventional inverter modules connected in parallel by using coupled reactors. This solution reduces the THD of the output voltage, despite the low switching frequency of transistors. The advantage of the proposed solution is also a relatively small rated power of the reactors. Proposed new arrangements for different...
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FPGA realization of an improved alpha max plus beta min algorithm
PublicationThe generalized improved version of the alpha max plus beta min square-rooting algorithm and its realization in the Field Programmable Gate Array (FPGA) are presented. The algorithm computes the square root to calculate the approximate magnitude of a complex sample. It is especially useful for pipelined calculations in the DSP. In case of four approximation regions it is possible to reduce the peak error form 3.95% to 0.33%. This...
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Elimination of Impulsive Disturbances From Stereo Audio Recordings Using Vector Autoregressive Modeling and Variable-order Kalman Filtering
PublicationThis paper presents a new approach to elimination of impulsive disturbances from stereo audio recordings. The proposed solution is based on vector autoregressive modeling of audio signals. Online tracking of signal model parameters is performed using the exponential ly weighted least squares algo- rithm. Detection of noise pulses an d model-based interpolation of the irrevocably distorted sampl es is realized using an adaptive, variable-order...
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Stable and degradable microgels linked with cystine for storing and environmentally triggered release of drugs
PublicationEnvironmentally sensitive, degradable microgels based on poly(N-isopropylacrylamide) (pNIPA) crosslinked with the diacryloyl derivative of cystine (BISS) were synthesized by applying surfactant-free emulsion polymerization. pNIPA contributed the sensitivity to temperature to the microgels and the cross-linker made them degradable and sensitive to pH. The morphology of the microgels was investigated by using scanning and transmission...
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Historical records of organic pollutants in sediment cores
PublicationAnalyses of sediment core samples are primary sources of historical pollution trends in aquatic systems. Determining organic compounds, such as POPs, in the dated sediments enables the estimation of their temporal concentration changes and the identification of the contaminant origin in local regions. Wars, large-scale fires, economical transitions, and bans on certain chemicals are reflected in the sediment organic compound concentrations....
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Comparison of luminescence (TL and OSL) dating results from selected loess profiles in SE Poland and the NW Ukraine
PublicationFive periglacial loess profiles, three from Poland and two from the Ukraine, were selected from dating luminescence methods (TL and OSL). In regional terms, they include loess of the Carpathin, peri-Carpathian and Podalia facies. 89 samples were collected for dating purposes from five profiles. Of these samples, 19 were OSL-dated. The function of TL and OSL date distribution for the same samples was presented on one chart. The...
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A simplified behavioral MOSFET model based on parameters extraction for circuit simulations.
PublicationThe paper presents results on behavior modeling of general purpose Metal-Oxide Semiconductor Field-Effect Transistor (MOSFET) for simulation of power electronics systems requiring accuracy both in steady-state and in switching conditions. Methods of parameters extraction including nonlinearity of parasitic capacitances and steady-state characteristics are based on manufacturer data sheet and externally measurable characteristics....
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Radioactivity of drilling cuttings from shale resources of the Lower Paleozoic Baltic Basin, Poland
PublicationFractionated drilling wastes originating from shale gas exploration in the Baltic Basin in Pomerania were subjected to the measurements of mean activity concentrations of naturally occurring radioactive materials (NORMs).To better understand rock structure and texture, the X-ray diffraction analysis (XRD) and scanning electron microscopy(SEM) observation were used. To compare activity concentration of radionuclides in bulk wastes...
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Novel 2-alkythio-4-chloro-N-[imino(heteroaryl)methyl]benzenesulfonamide Derivatives: Synthesis, Molecular Structure, Anticancer Activity and Metabolic Stability
PublicationA series of novel 2-alkythio-4-chloro-N-[imino-(heteroaryl)methyl]benzenesulfonamide derivatives, 8–24, were synthesized in the reaction of the N-(benzenesulfonyl)cyanamide potassium salts 1–7 with the appropriate mercaptoheterocycles. All the synthesized compounds were evaluated for their anticancer activity in HeLa, HCT-116 and MCF-7 cell lines. The most promising compounds, 11–13, molecular hybrids containing benzenesulfonamide...
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Application of the Anammox Process for Treatment of Liquid Phase Digestate
PublicationThe liquid phase of the digestate (LPD) contains a relatively high concentration of nitrogen, with total ammonium nitrogen being the dominant form of nitrogen, as well as other essential nutrients such as phosphorus and potassium. Consequently, it must be treated before it is released into the environment. However, there are no reports of co-purification of LPD in the anammox process in sequencing batch reactor with granular sludge,...
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Przegląd metod monitorowania stanu technicznego tranzystorów mocy
PublicationW artykule przedstawiono kilka metod monitorowania stanu technicznego tranzystorów mocy, które są lub mogą być wbudowane w układy przekształtnikowe. Celem artykułu jest określenie aktualnego stanu badań na ten temat. Prezentowane metody przeznaczone są do monitorowania istotnych objawów starzenia modułów mocy: rozwarstwiania struktury modułu na skutek termomechanicznego zmęczenia stopu lutowniczego, uszkodzeń połączeń drutowych...
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Measurements of Dispersed Phase Velocity in Two-Phase Flows in Pipelines Using Gamma-Absorption Technique and Phase of the Cross-Spectral Density Function
PublicationThis paper concerns the application of the gamma radiation absorption method in the measurements of dispersed phase velocity in two-phase flows: liquid–gas flow in a horizontal pipe- line and liquid–solid particles in a vertical pipe. Radiometric sets containing two linear 241Am gamma radiation sources and two NaI(Tl) scintillation detectors were used in the research. Due to the stochastic nature of the signals obtained from the...
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Remarks on the Subject of Back-Up Protection of Residual Current Devices
PublicationResidual current devices without integral overcurrent protection (RCCBs) are back-up protected by fuses or miniature circuit-breakers (MCBs). If the latter are used, special attention must be given to the coordination between an RCCB and an MCB. This paper indicates probable cases of the aforementioned devices coordination, in which back-up protection of the RCCB is not adequate. A laboratory test has shown that depending on the...
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Influence of Toll Collection Method on Motorways on Traffic Safety and Efficiency
PublicationThe paper presents the results of the effectiveness analysis for various forms of toll collection on motorway gates and their impact on safety and efficiency of traffic. The results from field tests that were performed on the A1 motorway in Rusocin were used for the analysis. The research included the analysis of the video image of driver behaviour on the way to the toll booths and at toll booths. The PTV VISSIM tool was used to...
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Modular power converter topologies for energy storage and electric power distribution systems
PublicationThis paper describes selected issues concerning realization of energy storage system (ESS) designed to operate in power distribution system. In order to achieve scalability of the system a modular approach is proposed. In addition to this different configuration of the system are analyzed, where depending on requirements and application a scalability in power, in energy capacity of energy storage resource and both in power and...
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Low speed permanent magnet synchronous generator for vertical axis wind turbine
PublicationThe paper presents design process and tests of a prototype low speed permanent magnet synchronous generator (PMSG) dedicated for the innovative vertical-axis wind turbine. The rated data of the designed generator are following: power - 15 kVA, voltage - 400 V (Y), rotation speed - 93.75 rpm. The design assumptions, chosen results of the design process and experimental tests of the prototype PMSG are presented. The considered PMSG...
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Experimental verification of a new method of loop resistance testing in low voltage systems with residual current devices
PublicationA periodical verification of the effectiveness of protection against electric shock shall be performed in low voltage systems. The scope of this verification includes loop impedance/resistance testing. If a residual current device is installed in a tested circuit, this testing is problematic. A residual current device trips out during the test, because of the high value of measurement current. This precludes the execution of the...
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A Note on Fractional Curl Operator
PublicationIn this letter, we demonstrate that the fractional curl operator, widely used in electromagnetics since 1998, is essentially a rotation operation of components of the complex Riemann–Silberstein vector representing the electromagnetic field. It occurs that after the wave decomposition into circular polarisations, the standard duality rotation with the angle depending on the fractional order is applied to the left-handed basis vector...
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Forced degradation studies of ivabradine and in silico toxicology predictions for its new designated impurities
PublicationAll activities should aim to eliminate genotoxic impurities and/or protect the API againstdegradation. There is a necessity to monitor impurities from all classification groups,hence ivabradine forced degradation studies were performed. Ivabradine was provedto be quite durable active substance, but still new and with insufficient stability data.Increased temperature, acid, base, oxidation reagents and...
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Improved methods for stator end winding leakage inductance calculation
PublicationCalculating the stator end-winding leakage inductance, taking into account the rotor, is difficult due to the irregular shape of the end-winding. The end-winding leakage may distribute at the end of the active part and the fringing flux of the air gap. The fringing flux belongs to the main flux but goes into the end-winding region. Then, not all the magnetic flux occurring in the end region is the end-winding leakage flux. The...
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Excitation-independent constant conductance isfet driver
PublicationA new constant conductance driver for ISFETs sensors has been developed. The proposed circuit maintains the sensor operating point at constant drain-source conductance. The combination of a simple, self-balancing resistance bridge and the subtraction half (or similar fraction) of source-drain voltage from the gate-source voltage provides the independence of output signal from current and voltage drivers instability. The use of...
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Routing Method for Interplanetary Satellite Communication in IoT Networks Based on IPv6
PublicationThe matter of interplanetary network (IPN) connection is a complex and sophisticated topic. Space missions are aimed inter alia at studying the outer planets of our solar system. Data transmission itself, as well as receiving data from satellites located on the borders of the solar system, was only possible thanks to the use of powerful deep space network (DSN) receivers, located in various places on the surface of the Earth. In...
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MIASTO PORTOWE – STRUKTURA, WYZWANIA FUNKCJONALNE I MODELE ROZWOJU
PublicationPort cities are having different spatial structure than those located inlands. As a result of their seaside location, they face specific administrative and functional problems on a daily basis. In the economic and settlement structure of the country, they usually play the role of a "gate" through which streams of cargo are distributed further over the whole hinterland. It is the transport and logistics function of port cities,...
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High Efficiency Dual-Active-Bridge Converter with Triple-Phase-Shift Control for Battery Charger of Electric Vehicles
PublicationAn optimal modulation scheme with triple-phase-shift (TPS) control could increase the efficiency in the entire load range for a dual-active-bridge (DAB) converter under wide output voltage range conditions. Therefore, this study proposes a convergent approach to TPS mode selection, coupled with an optimal modulation scheme, ensuring the circuit’s efficiency over the entire range in the realm of a high-power and high-efficiency...
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Evaluation of applicability of classic methods of a fault loop impedance measurement to circuits with residual current devices
PublicationMeasurement of fault loop impedance in low voltage grids and systems is in most cases performed to verify the effectiveness of protection against electric shock by automatic disconnection of supply. For the sake of measurement accuracy, it is advisable to perform it using large current. Unfortunately, in circuits with residual current devices which are very widely used nowadays, a large measurement current may trigger those devices...
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Reconstruction of 3D image of corona discharge streamer
PublicationIn this paper, the method of reconstruction of the 3D structure of streamers in DC positive corona discharge in nozzle-to-plate electrode configuration is presented. For reconstructing of 3D image of corona discharge streamer we propose a stereographical method, where streamers are observed from several directions simultaneously. The multi-directional observation enabled to obtain fine positional coordinates of streamers for a...
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Gesture Recognition With the Linear Optical Sensor and Recurrent Neural Networks
PublicationIn this paper, the optical linear sensor, a representative of low-resolution sensors, was investigated in the multiclass recognition of near-field hand gestures. The recurrent neural network (RNN) with a gated recurrent unit (GRU) memory cell was utilized as a gestures classifier. A set of 27 gestures was collected from a group of volunteers. The 27 000 sequences obtained were divided into training, validation, and test subsets....
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Accurate Computation of IGBT Junction Temperature in PLECS
PublicationIn the article, a new method to improve the accuracy of the insulated-gate bipolar transistor (IGBT) junction temperature computations in the piecewise linear electrical circuit simulation (PLECS) software is proposed and described in detail. This method allows computing the IGBT junction temperature using a nonlinear compact thermal model of this device in PLECS. In the method, a nonlinear compact thermal model of the IGBT is...
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Power equalization of AES FPGA implementation
PublicationThis paper briefly introduces side channel attacks on cryptographic hardware with special emphasis on differential power analysis(DPA). Based on existing countermeasures against DPA, design method combining power equalization for synchronous and combinatorialcircuits has been proposed. AES algorithm has been implemented in Xilinx Spartan II-E field programmable gate array (FPGA) deviceusing the standard and power-equalized methods....
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Chemical, Aroma and Pro-Health Characteristics of Kaffir Lime Juice—The Approach Using Optimized HS-SPME-GC-TOFMS, MP-OES, 3D-FL and Physiochemical Analysis
PublicationThe study aimed to provide the chemical, aroma and prohealth characteristics of the kaffir lime juice. A procedure using solid-phase microextraction with gas chromatography (SPME-GC-TOFMS) was optimized and validated for the determination of terpenes of kaffir lime. Main physicochemical parameters: pH, vitamin C, citric acid and °Brix were evaluated. Micro- and macro elements were determined using microwave plasma optic emission...
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Genotoxicity of selected pharmaceuticals, their binary mixtures, and varying environmental conditions – study with human adenocarcinoma cancer HT29 cell line
PublicationPharmaceutical residues are present in the environment in mixtures and their adverse effects may also result from interactions that occur between compounds. Studies presented in this work focus on genotoxicity of pharmaceuticals from different therapeutic groups in mixtures and in individual solutions impacted with different environmental conditions assessed using comet assay (alkaline approach). Binary mixtures of pharmaceuticals...
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New kagome prototype materials: discovery of KV3Sb5, RbV3Sb5, and CsV3Sb5
PublicationIn this work, we present our discovery and characterization of a new kagome prototype structure, KV3Sb5. We also present the discovery of the isostructural compounds RbV3Sb5 and CsV3Sb5. All materials exhibit a structurally perfect two-dimensional kagome net of vanadium. Density-functional theory calculations indicate that the materials are metallic, with the Fermi level in close proximity to several Dirac points. Powder and single-crystal...
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Magazynowanie energii elektrycznej i gospodarka wodorowa
PublicationW artykule dokonano przegl ą du aktualnych technologii magazynowania energii elektrycznej oraz zestawiono uzyskiwane parametry w aspekcie zastosowa ń w zasobnikach systemowych. Przedstawiono studium mo ż liwo ś ci magazynowania energii z odnawialnych ź róde ł energii (O Ź E) w zasobnikach akumulatorowych i elektrowniach szczytowo-pompowych w Polsce. Omówiono tak ż e mo ż liwo ś ci wykorzystania...
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Sprzętowa implementacja koprocesora dla zastosowań kryptograficznych
PublicationW pracy przedstawiono procedurę implementacji elektronicznej skrzynki podawczej z wykorzystaniem zasobów sprzętowych na płytce FPGA (Filed Programmable Gate Array) typu Virtex 4. Przedstawiono ogólna zasadę działania skrzynki podawczej oraz opisano parametry i właściwości poszczególnych modułów funkcjonalnych systemu tj.: modułu TFTP Trivia File Transfer Protocol), serwera WWW, funkcji skrótu oraz asymetrycznego algorytm kryptograficznego....
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Pulsed UV-irradiated Graphene Sensors for Ethanol Detection at Room Temperature
PublicationA graphene-based gas sensor fabricated in a FET (GFET) configuration and its sensitivity towards ethanol and methane is reported. Detection of ethanol at the level of 100 ppm was observed under pulsed UV irradiation and after cleaning by UV light in the N2 ambient. Reduction of the frequency of UV irradiation pulses resulted in increased changes in sensor resistance in the presence of ethanol. Improved sensing behavior was ascribed...
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FPGA-Based System for Electromagnetic Interference Evaluation in Random Modulated DC/DC Converters
PublicationField-Programmable Gate Array (FPGA) provides the possibility to design new “electromagnetic compatibility (EMC) friendly” control techniques for power electronic converters. Such control techniques use pseudo-random modulators (RanM) to control the converter switches. However, some issues connected with the FPGA-based design of RanM, such as matching the range of fixed-point numbers, might be challenging. The modern programming...
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FPGA Acceleration of Matrix-Assembly Phase of RWG-Based MoM
PublicationIn this letter, the field-programmable-gate-array accelerated implementation of matrix-assembly phase of the method of moments (MoM) is presented. The solution is based on a discretization of the frequency-domain mixed potential integral equation using the Rao-Wilton-Glisson basis functions and their extension to wire-to-surface junctions. To take advantage of the given hardware resources (i.e., Xilinx Alveo U200 accelerator card),...
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Quantum-correlation breaking channels, broadcasting scenarios, and finite Markov chains
PublicationOne of the classical results concerning quantum channels is the characterization of entanglementbreakingchannels [M. Horodecki et al., Rev. Math. Phys 15, 629 (2003)]. We address the questionwhether there exists a similar characterization on the level of quantum correlations which may gobeyond entanglement. The answer is fully affirmative in the case of breaking quantum correlationsdown to the, so called, QC (Quantum-Classical)...
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THE GENE CLONING, OVEREXPRESSION, PURIFICATION AND BIOCHEMICAL CHARACTERISATION OF A NEW COLD-ADAPTED β–GALACTOSIDASE FROM ARTHROBACTER SP. VII-4
PublicationINTRODUCTION. β-Galactosidase [EC 3.2.1.23] is an enzyme that catalyzes the hydrolysis of O-glycosidic linkages in galactosides. It is commercially used in dairy industry for the production of milk with reduced lactose content. Potentially, the best method for lactose removal under cooling conditions should be carried out with a cold-adapted enzyme. AIM. The aim of this study was to determine the taxonomic affiliation of the isolate...
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New Chalcones Derivatives With Potent Antitumor Activity And Their Metabolism In Vitro
PublicationChalcone derivatives exhibit a broad range of biological activities, with antioxidant and cytotoxic properties among the most studied. Despite numerous reports on chalcones as cytotoxic, and potentially anticancer agents, very little is know on their actual mechanism of activity. Generally, chalcones are considered as antimitotic agents, which interfere with tubulin assembly.We have recently developed a new class of chalcones with...
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Electrochemical simulation of metabolic reduction and conjugation reactions of unsymmetrical bisacridine antitumor agents, C-2028 and C-2053
PublicationElectrochemistry (EC) coupled with analysis techniques such as liquid chromatography (LC) and mass spectrometry (MS) has been developed as a powerful tool for drug metabolism simulation. The application of EC in metabolic studies is particularly favourable due to the low matrix contribution compared to in vitro or in vivo biological models. In this paper, the EC(/LC)/MS system was applied to simulate phase I metabolism of the representative...
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The relationship between standard reduction potentials of catechins and biological activities involved in redox control
PublicationRedox homeostasis involves factors that ensure proper function of cells. The excess reactive oxygen species (ROS) leads to oxidative stress and increased risk of oxidative damage to cellular components. In contrast, upon reductive stress, insufficient ROS abundance may result in faulty cell signalling. It may be expected that dietary antioxidants, depending on their standard reduction potentials (E°), will affect both scenarios....
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The site at the cape Zidine in Lopar in the context of coastal residential and commercial complexes of Rab Island
PublicationSince 2013, the “Archaeological topography of the island of Rab” project has approached the island’s archaeology holistically and interdisciplinary, tackling all periods and archaeological evidence present on the island. Nevertheless, mostly due to a large amount of new data, a significant segment of research is devoted to Roman residential and production complexes, located either in the island’s fields or along the coast. Thus,...