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Search results for: whole-genome sequencing
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Deep Learning-Based, Multiclass Approach to Cancer Classification on Liquid Biopsy Data
PublicationThe field of cancer diagnostics has been revolutionized by liquid biopsies, which offer a bridge between laboratory research and clinical settings. These tests are less invasive than traditional biopsies and more convenient than routine imaging methods. Liquid biopsies allow studying of tumor-derived markers in bodily fluids, enabling the development of more precise cancer diagnostic tests for screening, disease monitoring, and...
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Licht, Luft, Sonne und Farbe. Ucząc się dziś od Gustava Oelsnera
PublicationArtykuł przedstawia główne przesłanki podjęcia tematu całego tomu. Jest kluczem do powiązania wszystkich zamieszczonych w tomie prac, poruszających temat współczesnych interpretacji miasta, czerpiących z dorobku modernistycznych planistów i architektów - reformatorów miasta, oraz modernistycznej myśli architektonicznej i urbanistycznej. Główną postacią nie tylko tego artykułu, ale i całego tomu, jest Gustav Oelsner, architekt miejski...
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Prognozowanie wpływu drgań komunikacyjnych na budynki mieszkalne za pomocą sztucznych sieci neuronowych i maszyn wektorów wspierających
PublicationDrgania komunikacyjne mogą stanowić duże obciążenie eksploatacyjne budynku, powodując zarysowania i spękania tynków, odpadanie wypraw, zarysowania konstrukcji, pękanie elementów konstrukcji lub nawet zawalenie się budynku. Pomiary drgań na rzeczywistych konstrukcjach są pracochłonne i kosztowne, a co ważne nie w każdym przypadku są one uzasadnione. Celem pracy jest analiza autorskiego algorytmu, dzięki któremu z dużym prawdopodobieństwem...
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Uniwersalny program komputerowy do projektowania zmiany kierunku trasy
PublicationW pracy przedstawiono kolejny program komputerowy stanowiący implementację algorytmu obliczeniowego dotyczącego projektowania zmiany kierunku trasy kolejowej, dostosowanego do techniki ciągłych pomiarów satelitarnych. Program ten ma charakter uniwersalny, gdyż w ogólnym przypadku obejmuje wprowadzenie do układu geometrycznego dwóch łuków kołowych o różnym promieniu, czyli zastosowanie łuku koszowego. Może się to okazać szczególnie...
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Impact of adverse winter weather on traffic flow
PublicationThe paper aims to analyse the impact of adverse weather in winter on traffic flow using data from a dual carriageway section of an express road located in Gdansk. For the purposes of the analysis, traffic and meteorological data were collected for a period of 15 months in 2014-2015 and aggregated to 5 minutes intervals. The impact of winter weather conditions on traffic flow was assessed by comparing aggregated traffic stream parameters...
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Uniqueness or uniformity - studies of media architecture
PublicationA development of media architecture is presented in light of to such phenomena as aesthetization, consumerism and digitization. This article deals with media architecture in commercial spaces. Media solutions impact on the architectural skin, making it into visible and dynamic points of the image of a post-modern city. This article presents the specificity of media solutions, depending on the function of commercial activity buildings...
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Adaptabilność obiektów architektonicznych we współczesnym projektowaniu / The adaptability of architectural objects in contemporary design
PublicationThe article discusses the issue of adaptability - the ability to modify modern architectural objects to a changing context - as an important element of contemporary design. Adaptability can take on different forms. It is most commonly understood as a change in the architectural form in reaction to various stimuli from the environment through transformative structures, or as an object's ability to adapt to climatic conditions, providing...
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Peripheral industrial NUTS 3 sub-regions in the European Union – identification and typology
PublicationA common phenomenon of development is the big difference in its levels, especially between metropolitan and non-metropolitan areas. Non-metropolitan areas are also very different. In some of them, industry plays a big role. European Union’s NUTS 3 non-metropolitan low developed sub-regions, whose gross domestic product per capita in 2011 was below 75% of the EU average, were the subject of research. It is based on the data and...
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The emissions of monoaromatic hydrocarbons from small polymeric toys placed in chocolate food products
PublicationThe article presents findings on the emissions of selected monoaromatic hydrocarbons from children's toys placed in chocolate food products. The emission test system involved the application of a new type of microscale stationary emission chamber, μ-CTE™ 250. In order to determine the type of the applied polymer in the manufacture of the tested toys, Fourier transform infrared spectroscopy and thermogravimetric analysis coupled...
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HIERARCHICAL CYCLES IN MODERN POWER SYSTEMS – EXERGY ANALYSIS UNDER PART LOADS
PublicationThe aim of the paper is to investigate thermodynamic efficiency of advanced hierarchic power cyclesunder partial loads by using of exergy analyze. Advanced hierarchical power systems arecomposed of few energy conversion cycles, most common are steam and gas cycles in various configurations, but they may contain fuel cells, ORC, lithium bromide absorption chillers and others. Moreover hierarchical cycles can be powered by several...
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Polychlorinated biphenyls (PCBs) and polychlorodibenzo-p-dioxins (PCDDs) determination in disposable baby diapers with the application of natural deep eutectic solvent
PublicationIn this work a new method involving solvent extraction of porous membrane-packed solid samples (SE-PMSS) coupled to gas chromatography-mass spectrometry (GC–MS) has been developed for the determination of six polychlorinated biphenyls (PCBs) and five polychlorodibenzo-p-dioxines (PCDDs) in disposable baby diapers. In that aim, a terpenoid-based natural deep eutectic solvent (NADES) composed of carvone and camphor in a 1:1 M ratio...
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Numerical modelling of different airbag folding patterns and their influence on occupant responses in frontal vehicle impact
PublicationThis paper presented a procedure for airbag folding for the application in occupant safety studies and analysed the influence of different airbag folding patterns on the occupant severity in frontal impact. Airbags were folded in two patterns: zig-zag and top-roll, using two folding techniques: Initial Metric Method and Explicit Folding. The explicit folding was found to be more expensive in terms of preparation time. However,...
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Reception of Terrestrial DAB+ and FM Radio with a Mobile Device: A Subjective Quality Evaluation
PublicationNowadays, terrestrial broadcasting enables to receive content anytime and everywhere. People can obtain information both with a portable or desktop receiver, which include pocket-sized devices as well as high-end Hi-Fi equipment, not to mention car audio systems. Numerous manufacturers include FM-compatible chipsets in a variety of user equipment (UE), including mobile phones. However, digital radio signal processing modules, such...
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Macroeconomic functions of the Russian stock market
PublicationThe purpose of this article is to present the structure of the stock market in the Russian Federation and the significance of this part of national financial system for the whole economy, particularly the degree of main macroeconomic functions fulfillment. First part of the text includes an overview of the main theoretical concepts linked with the stock market roles as well as a brief description of results of selected studies...
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Late cultivars of cabbage can better cope with cadmium- involved stress than early one
PublicationThe usefulness of white cabbage (Brassica oleracea ssp. capitata L. f. alba) for phytoremediation of heavy metals (cadmium and zine) due to the rapid growth and a large biomass of its heads has been already described (Bączek-Kwinta et al., 2011. Kusznierewicz et al., 2012). As the photosynthetic apparatus supplies the whole plant with sugars necessary for various physiological processes and, in consequence, results in the yield,...
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Unusual structural properties of water within the hydration shell of hyperactive antifreeze protein
PublicationMany hypotheses can be encountered explaining the mechanism of action of antifreeze proteins. One widespread theory postulates that the similarity of structural properties of solvation water of antifreeze proteins to ice is crucial to the antifreeze activity of these agents. In order to investigate this problem, the structural properties of solvation water of the hyperactive antifreeze protein from Choristoneura fumiferana were...
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Application of Aqueous Biphasic Systems Extraction in Various Biomolecules Separation and Purification: Advancements Brought by Quaternary Systems
PublicationAqueous biphasic systems (ABS) extraction is a simple, selective, efficient and easy to scale-up technology that, over the years, has attracted a considerable attention from the researcher community as an alternative methodology in downstream processing of a wide variety of biomolecules. This review summarizes and discusses the fundamental features of ABS, as well as its advantages and disadvantages, as a separation and purification...
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Negative impact of constant RPM control strategy on ship NOx emission in waves
PublicationIn severe wave conditions, the ship propulsion system is loaded with high fluctuations due to external disturbances. The highly fluctuating loads enforce radical changes in the main engine torque, which in turn demands variation of the fuel rate injected into the cylinders if a constant rotational speed strategy is applied. Therefore, the temperature of gases varies to a large extent during the combustion process in the cylinders....
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Modernization and adaptation of historical interiors
PublicationModernization of the historical building's interior entails the need to take many decisions, often conflicting. Operational requirements, protection of the architectural heritage, fire-safety recommendations, construction regulations, all these aspects involve a whole set of problems that require a rational solution, respecting ambient architectural and historical value, as well as the needs arising from the planned transformation....
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Shaping New Generations of Managers and Consumers: CSR Implementation and Higher Education System in Poland
PublicationConsidering the Corporate Social Responsibility as a significant research and education topic for university staff, students, graduates and the whole society, has become a sign of our times. Universities and other education institutions, including the third sector, play an important role, incorporating CSR as a crosscutting issue, in particular into the curricula of future managers and graduate students, no matter the country we...
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Transport properties of microemulsions with ionic liquid apolar domains as a function of ionic liquid content
PublicationThe specific conductivity, dynamic viscosity and apparent diffusion coefficient of each of four aqueous ionic liquid microemulsions (IL-MEs) were measured as a function of ionic liquid (IL) content. The investigated systems were composed of water, hydrophobic ILs (1-butyl-3-methylimidazolium hexafluorophosphate or bis(trifluoromethanesulphonyl)imide) and the nonionic surfactant Triton X-100 or its mixture with cosurfactant (butanol)....
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Biomarkers of alcohol consumption in body fluids - possibilities and limitations of application in toxicological analysis
PublicationEthyl alcohol is the most popular legal drug, but its excessive consumption causes social problems. Despite many public campaigns against alcohol use, car accidents, instances of aggressive behaviour, sexual assaults and deterioration in labor productivity caused by inebriated people is still commonplace. Fast and easy diagnosis of alcohol consumption is required in order to introduce proper and effective therapy, and is crucial...
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Model of an Integration Bus of Data and Ontologies of Smart Cities Processes
PublicationThis paper presents a model of an integration bus used in the design of Smart Cities system architectures. The model of such a bus becomes necessary when designing high-level architectures, within which the silo processes of the organization should be seen from the perspective of its ontology. For such a bus to be used by any city, a generic solution was proposed which can be implemented as a whole or in part depending on the requirements...
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Nanostructuring of thin Au films deposited on ordered Ti templates for applications in SERS
PublicationIn this work the results on thermal nanostructuring of the Au films on Ti templates as well as morphology and optical properties of the obtained structures are reported. The bimetal nanostructures are fabricated in a multi-step process. First, the titania nanotubes are produced on the surface of Ti foil by anodization in an ethylene glycol-water solution containing fluoride ions. This is followed by chemical etching in oxalic acid...
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Optimization of Data Assignment for Parallel Processing in a Hybrid Heterogeneous Environment Using Integer Linear Programming
PublicationIn the paper we investigate a practical approach to application of integer linear programming for optimization of data assignment to compute units in a multi-level heterogeneous environment with various compute devices, including CPUs, GPUs and Intel Xeon Phis. The model considers an application that processes a large number of data chunks in parallel on various compute units and takes into account computations, communication including...
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Mathematical modelling and computer simulation of activated sludge systems.Second edition
PublicationMathematical Modelling and Computer Simulation of Activated Sludge Systems – Second Edition, provides, from the process engineering perspective, a comprehensive and up-to-date overview regarding various aspects of the mechanistic (“white box”) modelling and simulation of advanced activated sludge systems performing biological nutrient removal. In the new edition of the book, a special focus is given to nitrogen removal and an overview...
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Detection of the Plant Pathogen Pseudomonas Syringae pv. Lachrymans on Antibody-Modified Gold Electrodes by Electrochemical Impedance Spectroscopy
PublicationThe present work describes an impedimetric immunosensor for Pseudomonas syringae pv. lachrymans (Psl) detection. This pathogen infects many crop species causing considerable yield losses, thus fast and cheap detection method is in high demand. In the assay, the gold disc electrode was modified with 4-aminothiophenol (4-ATP), glutaraldehyde (GA), and anti-Psl antibodies, and free-sites were blocked with bovine serum albumin (BSA)....
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Mural - kiedy wandalizm staje się sztuką
PublicationCałość mojego referatu rozpoczęłam od przytoczenia opinii na temat tego czym tak naprawdę jest mural. Następnie skupiłam się na pochodzeniu współczesnego muralu. Odpowiedziałam na pytanie skąd, w jaki sposób i dlaczego pojawiły się rysunki ścienne. Przechodząc od malarstwa jaskiniowego sprzed 32 tysięcy lat, przez malarstwo starożytnego Egiptu, hasła wypisywane na murach starożytnego Rzymu, mural propagandowy Meksyku z lat 20....
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Cast iron in the 19th-century building equipment
PublicationCast iron is a material, characteristics of which enable to receive extremely artistic elements. It maintains good strength properties at the same time. That combination of these seemingly contrary traits makes it a commodity that was widely used in the 19th century industry and architecture. These usages were not only as decorative elements, technical and structural ones. The production of new household utilities started, which...
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Pavilion Hospitals Of West Prussia In The 19th Century – Evolution Of The Idea
PublicationIn the 19th century a number of modern curative and healthcare hospitals with complex functional and spatial layout were erected in the territory of the West Prussia. The largest of them were specialist centers treating physical and mental illnesses and disabilities: institutions for mentally ill patients (including addicts), epileptics and disabled people. Apart from the medical treatment section, there were administrative, social...
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IDENTIFICATION AND COMPARATIVE ANALYSIS OF FACTORS INFLUENCING ROAD SAFETY IN US REGIONS AND IN POLISH VOIVODESHIPS
PublicationAnalyses of road safety at national level have been run for many years and large number of publications concerning them appeared so far. How interdisciplinary the issue is, has been shown by literature studies done by the author of the paper. It appears that economists, mathematicians, doctors as well as engineers have studied the issue. It is not an easy one, as results of many analyses lead to conflicting conclusions and...
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The oil film parameters of the wankel engine apex seal in aspects of durability of mating elements
PublicationThe Wankel engine is one of only few alternatives to the reciprocating engines. The advantages such as good value of maximum engine power to its mass ratio are still present and can have great sense in selected fields of application, for example General Aviation. Nevertheless the disadvantages of the Wankel engine design have never lost its importance and still pose an obstacle to wider use of the Wankel engine. One of the main...
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Economical wood sawing with circular saw blades of a new design (Ekonomicno piljenje drva kruznom pilom novog dezajna)
PublicationMaterial-saving and energy-saving belong to the basic requirements imposed on contemporary manufacturing processes. The realization of these processes gives measurable profi ts, not only economical butalso ecological. In the case of wood sawing with circular saw blades, material- and energy-savings are dependent on total overall set of teeth (theoretical kerf) and teeth position accuracy in relation to the workpiece. Hence, it...
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The long-term properties of mineral-cement-emulsion mixtures
PublicationThis publication presents evaluation of long-term behavior of mineral-cement-emulsion (MCE) mixtures. MCE mixtures are among the major products of cold recycling of old asphalt pavements. They are composed by binding of the old materials reclaimed from the pavement and new mineral aggregate using two different binding agents – cement and bituminous emulsion. While bituminous emulsion dissolutes and binds materials quite fast, it...
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Linear revitalization - problems and challenges. Discursive article
PublicationThe aim of the article, defined by the author as discursive, is to give the answer as to whether within ‘revitalization’ we should distinguish the notion of ‘linear revitalization’ – not yet defined in Polish and English-language literature. The author presents the thesis that we should do so by presenting the idea, its specific character and its role. This kind of action seems to have, in the author’s opinion, a positive influence...
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Thermal and physical properties of ZrO2–AlO(OH) nanopowders synthesised by microwave hydrothermal method
PublicationIndustrially relevant nanopowder was synthesised by microwave hydrothermal synthesis to obtain well-controlled composition (ZrO2–AlO(OH) system) which was found to determine a number of physical and thermal characteristics. This study reports variation of particle size, density, specific surface area (SSABET), as well as thermal behaviour of nanopowder mixtures of ZrO2–AlO(OH) in the whole range of compositions. It was found that...
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Applications of Raman spectroscopy for detection of selected substances in tissues
PublicationThis dissertation explores the applications of Raman spectroscopy for biological tissue analysis. Basics of Raman and surface-enhanced Raman spectroscopy (SERS) are described, along with an analysis of the literature on biodetection and non-invasive blood analysis with emphasis on glucose detection. Instrumentation for Raman measurements is described. The sources of noise and interferences occurring in biological tissue measurements...
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INFOGEST static in vitro simulation of gastrointestinal food digestion
PublicationDeveloping a mechanistic understanding of the impact of food structure and composition on human health has increasingly involved simulating digestion in the upper gastrointestinal tract. These simulations have used a wide range of different conditions that often have very little physiological relevance, and this impedes the meaningful comparison of results. The standardized protocol presented here is based on an international consensus...
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Deep Learning Optimization for Edge Devices: Analysis of Training Quantization Parameters
PublicationThis paper focuses on convolution neural network quantization problem. The quantization has a distinct stage of data conversion from floating-point into integer-point numbers. In general, the process of quantization is associated with the reduction of the matrix dimension via limited precision of the numbers. However, the training and inference stages of deep learning neural network are limited by the space of the memory and a...
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The Idea of Using Bayesian Networks in Forecasting Impact of Traffic-Induced Vibrations Transmitted through the Ground on Residential Buildings
PublicationTraffic–induced vibrations may constitute a considerable load to buildings. In this paper, vibrations transmitted through the ground caused by wheeled vehicles are considered. This phenomenon may cause cracking of plaster, cracks in load-bearing elements or even, in extreme cases, collapse of the whole structure. Measurements of vibrations of real structures are costly and laborious. Therefore, the aim of the present paper is to...
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Electron scattering from 2-methyl–1,3-butadiene,C5H8, molecules: Role of methylation
PublicationWe report cross-section results from experimental and theoretical investigations into electron collisions with the 2-methyl–1,3-butadiene [C5H8] molecule. The current results are compared with our previous results for the 1,3-butadiene [C4H6] molecule, a structural homologue of 2-methyl–1,3-butadiene, to investigate how the methylation (the substitution of hydrogen atom by a methyl group) affects the shape and/or magnitude of the...
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Ionic liquids-based microextraction techniques
PublicationIn recent years, the development of highly efficient analytical techniques is of great importance, however, the direct analysis of complex sample matrix is still impossible in many cases. Therefore, the step of sample preparation is commonly involved in an analytical procedure. Over the years, it has been realized that the major source of inaccuracy and imprecision on general analysis results from the operations associated to sample...
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The evaluation of eGlasses eye tracking module as an extension for Scratch
PublicationIn this paper we present the possibility of using eGlasses eye tracking module as an extension for Scratch programming tool which is a visual programming language supporting computer skills learning. The main concept behind this project is to setup the interface for rapid interaction design. Eye tracking is a powerful tool for hands free communication but for that requires a dedicated software. This software is rarely tailored...
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Circular saw vibrations or dynamics of the spindle
PublicationSawing of wood with circular saws is a typical example of cutting with multi-blade tools. In that kind of cutting, theposition accuracy of following tool blades is a crucial factor which affects the cutting process and machining final effects.Position tooth errors may cause deterioration in cutting conditions, changes in loads of individual teeth and the tool as a whole,and also a decrease in accuracy and surface quality after...
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Aquaponics Based Artificial Biosphere Included in Architecture: From Mitigation of Negative Impacts to Positive Added Values of Urban Spatial Structures on Local, Regional and Global Scale
PublicationTechnologies may appear faster than spatial planning can afford it. Alt hough applying new technologies solve particular problems, it may also create new ones. Many negative consequences of implementing new technologies are visible a fter years or decades – they accumulate until the need of solving them. According to The Hannover Principles (McDonough & Braungart 2013) one should, by example not think about...
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Selected aspects of performance of organic Rankine cycles incorporated into bioenergy with carbon capture and storage using gasification of sewage sludge
PublicationThe study aims to investigate the application of the Organic Rankine Cycle (ORC) in the bioenergy with carbon capture and storage (BECCS) using gasification of sewage sludge. The tool used in the investigation is the Aspen Plus software with REFPROP property methods for calculating fluid properties. The reason for this study is that a detailed analysis of the proposed BECCS process flow diagram indicates that a certain amount of...
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Assessment, optimisation and working fluid comparison of organic rankine cycle combined with negative CO2 gas power plant system
PublicationThis study aims to investigate the application of the Organic Rankine Cycle (ORC) as an alternative to low-pressure expansion in the negative CO2 power plant (nCO2PP). The reason for this study is that a detailed analysis of nCO2PP indicates a certain amount of waste heat present in the exhaust gas from the high-to-intermediate pressure gas turbine. Some of this energy can be used by the application of the expansion in a low-pressure...
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Multi-core processing system for real-time image processing in embedded computer vision applications
PublicationW artykule opisano architekturę wielordzeniowego programowalnego systemu do przetwarzania obrazów w czasie rzeczywistym. Dane obrazu są przetwarzane równocześnie przez wszystkie procesory. System umożliwia niskopoziomowe przetwarzanie obrazów,np. odejmowanie tła, wykrywanie obiektów ruchomych, transformacje geometryczne, indeksowanie wykrytych obiektów, ocena ich kształtu oraz podstawowa analiza trajektorii ruchu. Ang:This paper...
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Post processing and selecting data obtain with parametric sub-bottom profiler SES-2000 Standard during sounding the Gulf of Gdansk
PublicationThe main goal of the paper is to describe the results of sounding the Gulf of Gdansk seabed using a parametric sub-bottom profiler SES-2000 Standard. Quality of obtained during trials data depends inter alia on proper location of antenna to reduce influence of pitch, roll, heave and ship noise (bubbles from propeller and a hull flow, vibration from main engine and peripheral devices). Furthermore calibration of complementary units...
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Differential expression profile between amygdala and blood during chronic lithium treatment in a rat model of depression – a pilot study
PublicationLithium is a mood stabilizer widely used in the pharmacotherapy of bipolar disorder and treatment‑resistant depression. Taking into account dysregulated inflammatory activity in depression and the immunomodulatory role of lithium, we hypothesized that genes associated with inflammatory responses may be potential biomarkers of lithium action. We aimed to compare gene expression changes between the brain and the periphery after...