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Search results for: middle mile delivery
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Encapsulation of Amikacin into Microparticles Based on Low-Molecular-Weight Poly(lactic acid) and Poly(lactic acid-co-polyethylene glycol)
PublicationThe aim of this study was to fabricate novel microparticles (MPs) for efficient and long-term delivery of amikacin (AMI). The emulsification method proposed for encapsulating AMI employed low-molecular-weight poly(lactic acid) (PLA) and poly(lactic acid-co-polyethylene glycol) (PLA−PEG), both supplemented with poly(vinyl alcohol) (PVA). The diameters of the particles obtained were determined as less than 30 μm. Based on an in-vitro...
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Electrically Conductive Carbon‐based (Bio)‐nanomaterials for Cardiac Tissue Engineering
PublicationA proper self-regenerating capability is lacking in human cardiac tissue which along with the alarming rate of deaths associated with cardiovascular disorders makes tissue engineering critical. Novel approaches are now being investigated in order to speedily overcome the challenges in this path. Tissue engineering has been revolutionized by the advent of nanomaterials, and later by the application of carbon-based nanomaterials...
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Diatomaceous earth as a drug-loaded carrier in a glass-ionomer cement
PublicationThe effect of a natural filler (diatomaceous earth [DE], a promising drug-delivery agent) and its content was investigated on the performance of a model glass-ionomer cement (GIC). Three sample series, differing in DE content (0, 2.5 and 5 wt%), were prepared using a commercial GIC as a matrix (3M Ketac Molar Easymix). The resultant surface microhardness and roughness, wear performance, and compressive strength of the samples were...
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Polysaccharide-based Nanocomposites for Biomedical Applications: A Critical Review
PublicationPolysaccharides (PSA) are taking specific position among biomaterials for advanced applications in medicine. Nevertheless, poor mechanical properties is known as the main drawback of PSA, which highlights need for PSA modification. Nanocomposites PSA (NPSA) are a class of biomaterials widely used as biomedical platforms, but despite their importance and worldwide use have not been reviewed. Herein we critically reviewed application...
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Criteria for evaluation and selection of the best offer for the Contract Engineer service
PublicationThe purpose of the legal regulations regarding public procurement in EU countries is to ensure effective funds' spending. When assessing and selecting the best offer, the contracting entities have at their disposal many different criteria, including non-price criteria. Their proper selection and application is necessary to ensure the high quality of the ordered product, delivery or service. Making an order for intellectual services,...
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Fabrication methods of smart composite coatings - review
PublicationPostoperative bacterial infections are one of the main reasons for unsuccessful implantation of long-term implants. The development of bacterial infection requires antibiotic therapy, in extreme cases a reimplantation procedure is necessary. In order to provide materials for implants with antibacterial properties, they are subjected to modifications to create a coating that will release the drug substance, when the inflammation...
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Stable and degradable microgels linked with cystine for storing and environmentally triggered release of drugs
PublicationEnvironmentally sensitive, degradable microgels based on poly(N-isopropylacrylamide) (pNIPA) crosslinked with the diacryloyl derivative of cystine (BISS) were synthesized by applying surfactant-free emulsion polymerization. pNIPA contributed the sensitivity to temperature to the microgels and the cross-linker made them degradable and sensitive to pH. The morphology of the microgels was investigated by using scanning and transmission...
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Potential for ITS/ICT Solutions in Urban Freight Management
PublicationThe article presents a study on applying ITS solutions in planning and management of urban freight transport in Gdynia. The traffic management system Tristar which is under implementation and its related systems show a potential to assist in development of freight transport measures. Recommendations for urban freight policy development supplementing Gdynia's Sustainable Urban Mobility Plan were used as a basis for identification...
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Time window based features extraction from temperature modulated gas sensors for prediction of ammonia concentration
PublicationElectronic gas recognition systems, in literature commonly referred as electronic noses, enable the recognition of a type and a concentration of various volatile compounds. Typical electronic gas-analyzing device consists of four main elements, namely, gas delivery subsystem, an array of gas sensors, data acquisition and power supply circuits and data analysis software. The commercially available metal-oxide TGS sensors are widely...
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Sustainable polymers targeted at the surgical and otolaryngological applications: Circularity and future
PublicationThe ongoing climate changes, high air and noise pollution have significant impact on humans’ health. This influence is especially visible in otolaryngology, which focuses on respiratory and hearing systems disfunctions. However, even though surgeries are done in response to diseases related to climate changes, they also have a negative impact on the environment, mostly connected with the inherence of single-use fossil fuel derived...
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Zdolni z Pomorza 2017/18 - Java i Android - podstawy programowania
e-Learning CoursesCel kursu: Celem kursu jest zapoznanie uczniów z podstawami w zakresie programowania w języku Java oraz z podstawami tworzenia aplikacji w środowisku Android. Opis kursu: Materiał przedstawiany na kursie będzie wprowadzał do zagadnień programowania w języku Java oraz środowiska Android. Od uczniów wymagana jest podstawowa wiedza w zakresie obsługi komputerów. Mile widziane są wcześniejsze doświadczenia w zakresie programowania...
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Zdolni z Pomorza 2018/19 - Java i Android - podstawy programowania
e-Learning CoursesCel kursu: Celem kursu jest zapoznanie uczniów z podstawami w zakresie programowania w języku Java oraz z podstawami tworzenia aplikacji w środowisku Android. Opis kursu: Materiał przedstawiany na kursie będzie wprowadzał do zagadnień programowania w języku Java oraz środowiska Android. Od uczniów wymagana jest podstawowa wiedza w zakresie obsługi komputerów. Mile widziane są wcześniejsze doświadczenia w zakresie programowania...
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ZzP - Podstawy budowania stron przy pomocy PHP7 - Spotkanie Akademickie 21.11.2020 r.
e-Learning CoursesSpotkanie poświęcone będzie zapoznaniu uczniów z podstawami w zakresie programowania w języku PHP7 przy tworzeniu dynamicznie generowanych treści stron internetowych. Przedstawiany materiał będzie wprowadzał do zagadnień programowania w języku PHP. Od uczniów wymagana jest podstawowa wiedza w zakresie obsługi komputerów, oraz tworzenia prostych stron internetowych za pomocą technologii HTML, CSS i JavaScript. Mile widziane są...
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From the Concept to Results: A Case Study on the Collection Development for the ODC–Opening Day Collection at Qatar National Library
Publication"A library collection should fit the mission for which it is created. The number of books it holds does not determine its worth." (E. J. Loveland, 2000) If so, how do we create a national library, and how do we build its collection from scratch without making many mistakes? Since 2012, when the plans for the new national library were announced, Qatar National Library (QNL) envisioned as carrying out its mission to "spread knowledge,...
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Circularly Polarized Antenna Array design with the Potential of Gain-Size Trade-off and Omnidirectional Radiation for Millimeter-Wave Small Base Station Applications
PublicationThis paper presents the design and validation of a slot-patch-hybrid circularly polarized antenna array for 28 GHz millimeter (mm) wave (mm-wave) applications. The proposed design has a simple geometry that facilitates the fabrication process, which is otherwise a challenging task due to the sub-mm dimensions of the circuit in the mm-wave band. In the proposed structure, aperture-coupled series slot-fed array is utilized to excite...
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ARCHITECTURE OF HYDROPOWER PLANTS IN POMORZE
PublicationThe history of energetic use of the rivers of Pomerania (Pomorze) is traced from the late Middle Ages. Their potential due to geographical specificity of the region was still attractive in the era of electricity of the19th and the first half of the 20th century. Configuration of the terrain, geological, and natural restrictions, but mainly energetic potential of particular localization were crucial for economical success of the...
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Ripple oscillations in the left temporal neocortex are associated with impaired verbal episodic memory encoding
PublicationBACKGROUND: We sought to determine if ripple oscillations (80-120 Hz), detected in intracranial electroencephalogram (iEEG) recordings of patients with epilepsy, correlate with an enhancement or disruption of verbal episodic memory encoding. METHODS: We defined ripple and spike events in depth iEEG recordings during list learning in 107 patients with focal epilepsy. We used logistic regression models (LRMs) to investigate the...
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Urban Mentoring as a new polish management technique in participatory planning
PublicationA decade of experience in implementation of numerous urban modernization projects in Poland resulted in a lively debate on socialization of the planning process, in which the matter of the public space quality has become the center of gravity. In those years, transformation from the classic administrative model of „bureaucracy planning” to the model of „management planning” has not been complete. The socialist primacy of the public...
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AeroSense Measurements: Wind Tunnel EPFL
Open Research DataData from wind tunnel tests of Aerosesne measurement system installed on NACA63418 at EPFL wind tunnel.
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Recent Advances in Polymer Nanocomposites: Unveiling the Frontier of Shape Memory and Self-Healing Properties—A Comprehensive Review
PublicationShape memory and self-healing polymer nanocomposites have attracted considerable attention due to their modifiable properties and promising applications. The incorporation of nanomaterials (polypyrrole, carboxyl methyl cellulose, carbon nanotubes, titania nanotubes, graphene, graphene oxide, mesoporous silica) into these polymers has significantly enhanced their performance, opening up new avenues for diverse applications. The...
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No Evidence for Sex-specificity in Vitamin C, E and Fatty Acid Content of Human Milk from Healthy Polish Mothers
PublicationHuman milk (HM) is a complex fluid that meets the nutritional needs of infants. Its composition idrfs associated with environmental, maternal, and foetal variables. It provides nutrients and bioactive substances, including cytokines, immunoglobulins, and constituents with antioxidative properties. Boys are reportedly more susceptible to oxidative stress. This study aimed to determine the relationship between infant sex and the...
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FFT analysis of temperature modulated semiconductor gas sensor response for the prediction of ammonia concentration under humidity interference
PublicationThe increasing environmental contamination forces the need to design reliable devices for detecting of the volatile compounds present in the air. For this purpose semiconductor gas sensors, which have been widely used for years, are often utilized. Although they have many advantages such as low price and quite long life time, they still lack of long term stability and selectivity. Namely, environmental conditions have significant...
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Transport of Particles in Intestinal Mucus under Simulated Infant and Adult Physiological Conditions: Impact of Mucus Structure and Extracellular DNA
PublicationThe final boundary between digested food and the cells that take up nutrients in the small intestine is a protective layer of mucus. In this work, the microstructural organization and permeability of the intestinal mucus have been determined under conditions simulating those of infant and adult human small intestines. As a model, we used the mucus from the proximal (jejunal) small intestines of piglets and adult pigs. Confocal...
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Molecular transformation of dissolved organic matter in manganese ore-mediated constructed wetlands for fresh leachate treatment
PublicationThe organic matter (OM) and nitrogen in Fresh leachate (FL) from waste compression sites pose environmental and health risks. Even though the constructed wetland (CW) can efficiently remove these pollutants, the molecular-level transformations of dissolved OM (DOM) in FL remain uncertain. This study reports the molecular dynamics of DOM and nitrogen removal during FL treatment in CWs. Two lab-scale vertical-flow CW systems were...
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Green porous benzamide-like nanomembranes for hazardous cations detection, separation, and concentration adjustment
PublicationGreen biomaterials play a crucial role in the diagnosis and treatment of diseases as well as health-related problem-solving. Typically, biocompatibility, biodegradability, and mechanical strength are requirements centered on biomaterial engineering. However, in-hospital therapeutics require an elaborated synthesis of hybrid and complex nanomaterials capable of mimicking cellular behavior. Accumulation of hazardous cations like...
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Zdolni z Pomorza 2018/19 - HTML5 - podstawy programowania
e-Learning CoursesCel kursu: Celem kursu jest zapoznanie uczniów z podstawami w zakresie programowania w języku HTML5 oraz z podstawami tworzenia aplikacji w środowisku JavaScript. Opis kursu: Materiał przedstawiany na kursie będzie wprowadzał do zagadnień programowania w języku HTML5 oraz CSS3 i Java Script. Od uczniów wymagana jest podstawowa wiedza w zakresie obsługi komputerów. Mile widziane są wcześniejsze doświadczenia w zakresie programowania...
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Zdolni z Pomorza 2017/18 - HTML5 - podstawy programowania
e-Learning CoursesCel kursu: Celem kursu jest zapoznanie uczniów z podstawami w zakresie programowania w języku HTML5 oraz z podstawami tworzenia aplikacji w środowisku JavaScript. Opis kursu: Materiał przedstawiany na kursie będzie wprowadzał do zagadnień programowania w języku HTML5 oraz CSS3 i Java Script. Od uczniów wymagana jest podstawowa wiedza w zakresie obsługi komputerów. Mile widziane są wcześniejsze doświadczenia w zakresie programowania...
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Permanent traffic count stations - expressway S6 Poland 2016
Open Research DataThe data includes traffic data from permanent traffic count stations located on the expressway S6 in the Tri-City Agglomeration area in Poland. The data covers the 12 months of 2016.
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History of World Architecture I 2022/23
e-Learning CoursesThe course History of World Architecture I (HWA I) is obligatory on the first semester of study at the Faculty of Architecture at Gdańsk University of Technology. It lasts 15 weeks , finishes with the exam and consists of 15 two-hour lectures and 15 two-hour exercises. The merit of the course includes the Western World architecture, beginning from Prehistory and Antiquity (Sumer, Egypt, Greece, Rome), up to the end of the Middle...
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Pregnane X receptor dependent up-regulation of CYP2C9 and CYP3A4 in tumor cells by antitumor acridine agents, C-1748 and C-1305, selectively diminished under hypoxia
PublicationInduction of proteins involved in drug metabolism and in drug delivery has a significant impact on drug-drug interactions and on the final therapeutic effects. Two antitumor acridine derivatives selected for present studies, C-1748 (9-(2’-hydroxyethylamino)-4-methyl-1-nitroacridine) and C-1305 (5-dimethylaminopropylamino-8-hydroxy-triazoloacridinone), expressed high and low susceptibility to metabolic transformations with liver...
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Progress in ATRP-derived materials for biomedical applications
PublicationThe continuing wave of technological breakthroughs and advances is critical for engineering well- defined materials, particularly biomaterials, with tailored microstructure and properties. Over the last few decades, controlled radical polymerization (CRP) has become a very promising option for the synthesis of precise polymeric materials with an unprecedented degree of control over mo lecular architecture. Atom transfer radical...
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Effect of pH on optical sensing with poly-L-lysine-modified nanodiamonds
PublicationNitrogen-vacancy (NV) centers are crystallographic defects which provide diamonds with unique physical properties. The centers are known for their intensive, time-stable fluorescence, and an electron spin, which exhibits long coherence time and may be manipulated using external stimuli. Nanodiamonds containing the NV centers are promising tools in biolabeling, biosensing, and drug delivery due to the aforementioned properties of...
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Muramyl dipeptide-based analogs as potential anticancer compounds: Strategies to improve selectivity, biocompatibility, and efficiency
PublicationAccording to the WHO, cancer is the second leading cause of death in the world. This is an important global problem and a major challenge for researchers who have been trying to find an effective anticancer therapy. A large number of newly discovered compounds do not exert selective cytotoxic activity against tumorigenic cells and have too many side effects. Therefore, research on muramyl dipeptide (MDP) analogs has attracted interest...
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Investigation on domestic fruits seed oils in personal care emulsion systems
PublicationThe use of fruit seed oils in personal care products is of significance to both their function and image. Poland is an important processor of fruit products within the EU, and thus has a large availability of seeds from domestic fruits, which are normally considered to be a waste material. Unfortunately, current literature is scarce of the suitability of these oils for topical use in the form of cosmetic emulsions. Published data...
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Mechanism of Binding of Antifungal Antibiotic Amphotericin B to Lipid Membranes: An Insight from Combined Single-Membrane Imaging, Microspectroscopy, and Molecular Dynamics
PublicationAmphotericin B is a lifesaving polyene antibiotic used in the treatment of systemic mycoses. Unfortunately, the pharmacological applicability of this drug is limited because of its severe toxic side effects. At the same time, the lack of a well-defined mechanism of selectivity hampers the efforts to rationally design safer derivatives. As the drug primarily targets the biomembranes of both fungi and humans, new insights into the...
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A Concept of Freight Traffic Flow Regulations in the City of Gdansk
PublicationThis paper presents a review of state-of-art efforts in urban freight transport modelling in the context of their requirements and applicability as a basis for evaluation of city's freight transport policy. Freight transport mirrors all aspects of the city's economic activity and for that reason its proper planning is of extreme importance. However, urban freight system may be considered as the most varied and fragmented element...
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Nutrient transport and acquisition by diatom chains in a moving fluid
PublicationThe role of fluid motion in delivery of nutrients to phytoplankton cells is a fundamental question in biological and chemical oceanography. In the study of mass transfer to phytoplankton, diatoms are of particular interest. They are non-motile, are often the most abundant components in aggregates and often form chains, so they are the ones expected to benefit most from enhancement of nutrient flux due to dissipating turbulence....
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Release systems based on self-assembling RADA16-I hydrogels with a signal sequence which improves wound healing processes
PublicationSelf-assembling peptides can be used for the regeneration of severely damaged skin. They can act as scaffolds for skin cells and as a reservoir of active compounds, to accelerate scarless wound healing. To overcome repeated administration of peptides which accelerate healing, we report development of three new peptide biomaterials based on the RADA16-I hydrogel functionalized with a sequence (AAPV) cleaved by human neutrophil elastase...
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Zdolni z Pomorza 2019/20 - Podstawy budowania stron przy pomocy PHP7
e-Learning CoursesCel kursu: Celem kursu jest zapoznanie uczniów z podstawami w zakresie programowania w języku PHP7 przy tworzeniu dynamicznie generowanych treści stron internetowych. Opis kursu: Materiał przedstawiany na kursie będzie wprowadzał do zagadnień programowania w języku PHP. Od uczniów wymagana jest podstawowa wiedza w zakresie obsługi komputerów, oraz tworzenia prostych stron internetowych za pomocą technologii HTML, CSS i JavaScript....
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Zdolni z Pomorza 2020/21 - Rozszerzenie możliwości prezentacji treści stron internetowych przy użyciu skryptów PHP
e-Learning CoursesCel kursu: Celem kursu jest zapoznanie uczniów z podstawami w zakresie programowania w języku PHP7 przy tworzeniu dynamicznie generowanych treści stron internetowych. Opis kursu: Materiał przedstawiany na kursie będzie wprowadzał do zagadnień programowania w języku PHP. Od uczniów wymagana jest podstawowa wiedza w zakresie obsługi komputerów, oraz tworzenia prostych stron internetowych za pomocą technologii HTML, CSS i JavaScript....
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Heart rate PPG signals with acceleration captured at wrist during small and moderate body movements
Open Research DataHeart rate PPG signals with acceleration captured at wrist during small and moderate body movements
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Database of the thermal ablation model
Open Research DataThermal ablation is a low invasive technique which eliminates cancerous tissue using high temperature. The presented database was used to show the temperature distribution for t=600[s] in two cases: when the value of the thermal conductivity of tissue k(x;T) is constant and for the variable k(x;T). In addition, using these data we showed the difference...
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Theory and application of Near-infrared spectroscopy
PublicationIn recent years one can observe a significant increase in the requirements on quality control in all industrial sectors. The growing number of involved analyses makes the traditional, time consuming, requiring use of large quantities of reagents, thus expansive methods inconvenient especially for industrial applications. Fortunately, there is a very fast, cheap and not invasive analytical method that is increasingly used in qualitative...
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INFOGEST inter-laboratory recommendations for assaying gastric and pancreatic lipases activities prior to in vitro digestion studies
PublicationIn vitro digestion studies often use animal digestive enzyme extracts as substitutes of human gastric and pancreatic secretions. Pancreatin from porcine origin is thus commonly used to provide relevant pancreatic enzymes such as proteases, amylase and lipase. Rabbit gastric extracts (RGE) have been recently introduced to provide gastric lipase in addition to pepsin. Before preparing simulated gastric and pancreatic extracts with...
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Comparing the permeability of human and porcine small intestinal mucus for particle transport studies
PublicationThe gastrointestinal mucus layer represents the last barrier between ingested food or orally administered pharmaceuticals and the mucosal epithelium. This complex gel structure plays an important role in the process of small intestinal absorption. It provides protection against hazardous particles such as bacteria but allows the passage of nutrients and drug molecules towards the intestinal epithelium. In scientific research, mucus...
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URBAN MENTORING JAKO NOWA TECHNIKA WPRÓŁPRACY W PROCESIE PLANOWANIA PARTCYPACYJNEGO
PublicationW 25 lat od powrotu demokracji opierającej się o neoliberalny paradygmat rozwoju kraju, Polska przyjęła Krajową Politykę Miejską 2030. Wraz z ustawą o rewitalizacji w nowoczesny sposób określa ona pole współpracy władz samorządowych i administracji z mieszkańcami, przejście do drugiej fazy rozwoju społeczeństwa demokratycznego – mieszkańców współgospodarzy przestrzeni miast. Powolna ewolucja tej relacji, silnie obarczonej dziedzictwem...
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A multi‑criteria approach to investigate spatial distribution,sources, and the potential toxicological effect of polycyclic aromatic hydrocarbons (PAHs) in sediments of urban retention tanks
PublicationBottom sediments deposited in retention tanks (RTs) located on two urban streams (Oliwski and Strzyza) in the central part of Gdansk (Poland) were analysed for polycyclic aromatic hydrocarbons’ (PAHs) content. PAHs were extracted from samples with methylene chloride, then the extracts were subjected to clean-up applying the solid phase extraction (SPE) method. Quantitative and qualitative determination of 16 PAHs was performed...
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Bacteriophages as potential tools for use in antimicrobial therapy and vaccine development
PublicationThe constantly growing number of people suffering from bacterial, viral, or fungal infections, parasitic diseases, and cancers prompts the search for innovative methods of disease prevention and treatment, especially based on vaccines and targeted therapy. An additional problem is the global threat to humanity resulting from the increasing resistance of bacteria to commonly used antibiotics. Conventional vaccines based on bacteria...
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Electrophoretic Deposition of Chitosan/Eudragit E 100/AgNPs Coatings for Controlled Release of Antibacterial Substance
PublicationThe development of bacterial infection of the tissues surrounding an implant is one of the leading causes of implant surgery failure. In order to prevent the deposition of bacteria on the implant surface and the formation of biofilm, coatings that exhibit antibacterial properties are manufactured. However, the problem is the controlled release of the therapeutic substance from the coating over the extended life of the implant [1],...
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Quantum dots conjugates with unsymmetrical bisacridines enhance cytotoxicity of these antitumor compounds in lung cancer cells and have protecting effects on normal cells
PublicationBackground: In recent years, with the rapid development of nanotechnology and its extensive applications in the medicine, nanocarriers for anticancer drug delivery have gained a great importance. Spherical semiconductor nanocrystals, frequently called quantum dots (QDs) are very attractive nanomaterials for bioimaging applications and they possess properties as potential candidates for drug carrier. Unsymmetrical bisacridines (UAs),...