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Search results for: Human Development
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To donate or not to donate? Future healthcare professionals’ opinions on biobanking of human biological material for research purposes
PublicationBackground Over the last few decades biobanks have been recognised as institutions that may revolutionisebiomedical research and the development of personalised medicine. Poland, however, still lacks clear regulationsregarding the running of biobanks and the conducting of biomedical research. While the awareness of the generalpublic regarding biobanks is low, healthcare professions and medical students also...
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Adopting Collaborative Games into Agile Requirements Engineering
PublicationIn agile software development, where great emphasis is put on effective informal communication involving diverse stakeholders, success depends on human and social factors. Not surprisingly, the Agile Manifesto advocates principles and values such as “individuals and interactions over processes and tools”, “focus on the customer”, “collaborate regularly”, “communicate face-to-face within the team” and “have regular team introspection”....
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Xanthone synthetic derivatives with high anticandidal activity and positive mycostatic selectivity index values
PublicationWith the current massive increases in drug-resistant microbial infection as well as the significant role of fungal infections in the death toll of COVID-19, discovering new antifungals is extremely important. Natural and synthetic xanthones are promising derivatives, although only few reports have demonstrated their antifungal mechanism of action in detail. Newly synthetized by us xanthone derivative 44 exhibited strong antifungal...
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Arsenic-Based Warfare Agents: Production, Use, and Destruction
PublicationSince the beginning of time, civilizations have looked for more creative ways to dominate and defeat their enemies. The rapid development of the chemical industry just before the Second World War started the era of modern chemical weapon production based on poisons, including toxic arsenic compounds. This paper provides a detailed overview of the production, usage and destruction of this dangerous chemical weapon. Milestones include:...
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Factors hindering and boosting SDG7 implementation in EU countries
PublicationOne of the sustainable development goals (SDG7) is to ensure access to clean and affordable energy, which is related to most other SDGs and plays a crucial role in eco - nomic development and human well-being. The aim of the article is to identify factors that enhance and delay one of the most crucial goals of sustainable development, SDG7. The study’s originality lies in the spatiotemporal approach to analysing the impact of...
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Tacit knowledge influence on intellectual capital and innovativeness in the healthcare sector: A cross-country study of Poland and the US
PublicationThis study provides empirical proof that whole organizational innovativeness is rooted in tacit knowledge due to its potency of human capital creation and, that a learning culture composed of a learning climate and mistakes acceptance component fosters human capital development. The main practical implication is that if the IC components are externally rather than internally determined in the particular organization embedded in...
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CULTURAL DETERMINANTS OF EVIDENCE-BASED HUMAN RESOURCES MANAGEMENT: A CROSS-COUNTRY ANALYSIS
PublicationPurpose: This paper aims at providing comparative analysis of the influence of cultural determinants on the managers’ perceptions of human resources management practices, as a factor conditioning application of evidence-based management. Design/methodology/approach: This article presents the study of 121 managers in Poland, on their perception of HRM practices and analyses the consistency of findings with the Hofstede cultural...
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Electronic nose algorithm design using classical system identification for odour intensity detection
PublicationThe two elements considered crucial for constructing an efficient environmental odour intensity monitoring systems are sensors and algorithms typically addressed to as electronic nose sensor (e-nose). Due to operational complexity of biochemical sensors developed in human bodies algorithms based on computational methods of artificial intelligence are typically considered superior to classical model based approaches in development...
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Analytical aspects of model compounds toxicity assessment using MTT and Microtox bioanalytica assays
PublicationMore and more increased intensity of anthropopressure processes can be observed, among other things, in the release of great quantities of synthetic substances into the environment, including the Endocrine Disrupting Compounds. The effects of the above-mentioned human impact on the environment not only can be noticed in the homeostasis disturbance in ecosystems, but they are also visible with respect to human. The high incidence...
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Virtual Sightseeing in Immersive 3D Visualization Lab
PublicationThe paper describes the modern Immersive 3D Visualization Lab (I3DVL) established at the Faculty of Electronics, Telecommunications and Informatics of the Gdańsk University of Technology (GUT) and its potential to prepare virtual tours and architectural visualizations on the example of the application allowing a virtual walk through the Coal Market in Gdańsk. The paper presents devices of this laboratory (CAVE, walk simulator etc.),...
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Sophistication assessment of existing FEM models of orbital blowout trauma: Is models valuation justified?
PublicationAfter a thorough study of the work entitled “Development and validation of an optimized finite element model of the human orbit”, some doubts aroused concerning the sophistication assessment of the existing finite element method (FEM) models of orbital blow-out. Although the work was unquestionably innovative, and the results were not only fascinating but also invaluable, the authors stated that their model was the most sophisticated...
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Peptidoglycan hydrolases - potential weapons against Staphylococcus aureus
PublicationBacteria of the genus Staphylococcus are common pathogens responsible for a broad spectrum of human and animal infections and belong to most important etiological factors causing food poisoning. Because of rapid increase in prevalence of isolation of staphylococci resistant to many antibiotics, there is an urgent need for development of new alternative chemotherapeutics. A number of studies have recently demonstrated the strong...
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DNA-damaging imidazoacridinone C-1311 induces autophagy followed by irreversible growth arrest and senescence in human lung cancer cells
PublicationImidazoacridinone 5-diethylaminoethylamino-8-hydroxyimidazoacridinone (C-1311) is an antitumor inhibitor of topoisomerase II and FMS-like tyrosine kinase 3 receptor. In this study, we describe the unique sequence of cellular responses to C-1311 in human non-small cell lung cancer (NSCLC) cell lines, A549 and H460. In A549 cells, C-1311 (IC80 = 0.08 µM) induced G1 and G2/M arrests, whereas H460 cells (IC80 = 0.051 µM) accumulated...
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Development of Biocompatible Fe3O4@SiO2 Nanoparticles as Subcellular Delivery Platform for Glucosamine-6-phosphate Synthase Inhibitors
PublicationNumerous inhibitors of glucoseamine-6-phophate synthase (GlcN-6-P), the enzyme responsible from catalysis of the first step of metabolic pathway leading to metabolism 5’-diphospho-N-acetyl-D- glucosamine, were reported as effective agents for inhibiting the growth of various fungal pathogens. Among the reported inhibitors,...
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Butyrylcholinesterase signal sequence self-aggregates and enhances amyloid fibril formation in vitro
PublicationAlzheimer’s disease (AD) pathogenesis has been attributed to extracellular aggregates of amyloid β (Aβ) plaques and neurofibrillary tangles in the human brain. It has been reported that butyrylcholinesterase (BChE) also accumulates in the brain Aβ plaques in AD. We have previously found that the BChE substitution in 5′UTR caused an in-frame N-terminal extension of 41 amino acids of the BChE signal peptide. The resultant variant...
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Concept of 'Good Urban Governance' and Its Application in Sustainable Urban Planning
PublicationContemporary urban theory and practice in the post-industrial era is increasingly often turning towards an approach based on sustainable development. That concept bearing the traits of a paradigm has grown on the ground of broad quest for an alternative to the existing development model of the industrial civilisation. It has gained wide social acceptance and is the basis for many development and environmental programmes at the...
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Indykatory dla modelu społeczeństwa informacyjnego.
PublicationW dobie postępującej informatyzacji, w czasach nazywanych często trzecią rewolucją technologiczną, synonimem ich jest społeczeństwo informacyjne IS (Information Society). Najpopularniejszy obecnie sposób, służący do szeregowania społeczeństw według ich stopnia rozwoju, jest oparty na HDI (Human Development Index). HDI jest wyliczany jako kombinacja trzech wyznaczników: longevity, knowledge, and a decent standard of living. Postanowiono,...
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Critical review of electronic nose and tongue instruments prospects in pharmaceutical analysis
PublicationElectronic nose (enose, EN) and electronic tongue (etongue, ET) have been designed to simulate human senses of smell and taste in the best possible way. The signals acquired from a sensor array, combined with suitable data analysis system, are the basis for holistic analysis of samples. The efficiency of these instruments, regarding classification, discrimination, detection, monitoring and analytics of samples in different types...
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Induction of G2/M phase arrest and apoptosis of human pancreatic cancer BxPC-3 cells by potenet antitumor 1-nitroacridine derivative C-1748
PublicationPancreatic ductal adenocarcinoma (PDA) is among the most lethal human cancers, in part because it is insensitive to many chemotherapeutic drugs. Gemcitabine still remains the best chemotherapeutic agent available for the treatment of advanced pancreatic cancer. However, gemcitabine treatment results in only a marginal survival advantage. Thus, there is a strong need for the continuous development of novel therapeutic agents...
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Fluorescence studies by quenching and protein unfolding on the interaction of bioactive compounds in water extracts of kiwi fruit cultivars with human serum albumin
PublicationThe main aim of this investigation was to characterize new kiwi fruit cultivars after cold storage treatment and to determine the similarities and differences between them, using spectroscopic methods. The chemometric comparison of kiwi fruit cultivars based on physicochemical indices during cold storage was carried out. All kiwi fruit cultivars showed a high level of correlation between the contents of phenolic compounds (polyphenols,...
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Reactive Processing and Functionalization of Ground Tire Rubber
PublicationThe dynamic development of the automotive industry resulted in a sig- nificant increase in rubber wastes, especially end-of-life tires, which are a serious threat to the natural environment and human health. This situation has enforced the industry and academic research groups to search new and cost-effective methods for recycling waste tires. In this field of research, reactive processing and functionaliza- tion seem to be a...
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Antioxidants: a premature scientific hypothesis that reshuffled the traditional food pyramid
PublicationAntioxidants present in substantial amounts in foods, plant-based products in particular, have been suggested as chemopreventive agents that can curb the development of undesirable health effects caused by oxidative stress simply by enriching diet in such compounds. This idea has been enthusiastically accepted by consumers, as well as food and pharmaceutical industry, and created great demand for products containing antioxidant...
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FEX a Fingers Extending eXoskeleton for Rehabilitation and Regaining Mobility
PublicationThis paper presents the design process of an exoskeleton for executing human fingers’ extension movement for the rehabilitation procedures and as an active orthosis purposes. The Fingers Extending eXoskeleton (FEX) is a serial, under-actuated mechanism capable of executing fingers’ extension. The proposed solution is easily adaptable to any finger length or position of the joints. FEX is based on the state-of-art FingerSpine serial...
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Trade differentiation and the characteristics of new imported and exported products - international panel data analysis
PublicationDrawing on o large panel of international economies we have shown how the set of imported and exported products evolves in economic growth process. Strong activity at the extensive margin, manifested through the rise in the number of active export and import lines, is typical for early stages of development. Trade diversification tendency, typical for a predominant mass of observations in our panel, is associated with changes in...
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Addressing the Weaknesses of Multi-Criteria Decision-Making Methods using Python
PublicationThe book aims to draw attention to the weaknesses in Multi-Criteria Decision-Making (MCDM) methods and provide insights to improve the decision-making process. By addressing these weaknesses, it seeks to enhance the accuracy and effectiveness of MCDM methods in selecting the best alternatives in various fields. The book covers popular MCDM methods such as TOPSIS, ELECTRE, VIKOR, and PROMETHEE. It compares traditional methods with...
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Digital Gaps and Economic Inequalities in MENA Countries: An Empirical Investigation
PublicationThis research contributes to the present state of the art by examining changes in cross-country inequalities in digital technologies deployment and economic performance. Our empirical target builds on the hypothesis that rapid global diffusion of digital technologies unequivocally leads to gradual eradication of cross-country digital gaps and cross-country inequalities in terms of deployment of ICT; the technology convergence occurs....
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A case study of odour nuisance evaluation in the context of integrated urban planning
PublicationOdour nuisance poses a serious problem in many urban areas, yet its evaluation and mitigation is often omitted in the urban planning process. By identifying its range and spatio-temporal variations, it could be taken into consideration by planners in urban development strategies and land use decisions. The aim of the study was to present the application of odour evaluation techniques in the improvement of the quality of life in...
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An electronic nose based on the semiconducting and electrochemical gas sensors
PublicationThe practical application of human nose for fragrance recognition is severely limited by the fact that our sense of smell is subjective and gets tired easily. Consequently, there is a significant need for an instrument that can be a substitution of the human sense of smell. Development of an electronic nose devices is an active area of research starting from pioneering research of Dodd and Persuad in the mid-1980s. Such systems...
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Mutagenic and Carcinogenic Compounds in Food
PublicationFood is a major environmental human cancer risk factor. One of the reasons for this is that food products contain substances that exhibit mutagenic and carcinogenic potential which may induce the transformation of normal somatic cells into cancerous cells. These compounds occur in food as a result of microbial contaminations (mycotoxins produced by molds), are generated from natural food components upon processing (e.g. heterocyclic...
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On Unsupervised Artificial-Intelligence-Assisted Design of Antennas for High-Performance Planar Devices
PublicationDesign of modern antenna structures is a challenging endeavor. It is laborious, and heavily reliant on engineering insight and experience, especially at the initial stages oriented towards the devel-opment of a suitable antenna architecture. Due to its interactive nature and hands-on procedures (mainly parametric studies) for validating suitability of particular geometric setups, typical antenna development requires many weeks...
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Dowodzenie w Policji – koncepcja zmian w zakresie dowodzenia formacją
PublicationThe dynamic development of human civilization at the turn of the 20th and 21st centuries unfortunately generates not only positive developments. So we need to constantly improve crisis management systems. The purpose of the research was to improve the police command system. Primarily, the research was based on the methods of non-standard observation and analysis and logical construction. The article presents the command in the...
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Emotion Recognition - the need for a complete analysis of the phenomenon of expression formation
PublicationThis article shows how complex emotions are. This has been proven by the analysis of the changes that occur on the face. The authors present the problem of image analysis for the purpose of identifying emotions. In addition, they point out the importance of recording the phenomenon of the development of emotions on the human face with the use of high-speed cameras, which allows the detection of micro expression. The work that was...
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Collective citizens' behavior modelling with support of the Internet of Things and Big Data
PublicationIn this paper, collective human behaviors are modelled by a development of Big Data mining related to the Internet of Things. Some studies under MapReduce architectures have been carried out to improve an efficiency of Big Data mining. Intelligent agents in data mining have been analyzed for smart city systems, as well as data mining has been described by genetic programming. Furthermore, artificial neural networks have been discussed...
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From Knowledge based Vision Systems to Cognitive Vision Systems: A Review
PublicationComputer vision research and applications have their origins in 1960s. Limitations in computational resources inherent of that time, among other reasons, caused research to move away from artificial intelligence and generic recognition goals to accomplish simple tasks for constrained scenarios. In the past decades, the development in machine learning techniques has contributed to noteworthy progress in vision systems. However,...
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A prototype information system for managing and pricing e-waste
PublicationThere is no doubt that innovation drives development in all areas of human activity, including electrical and electronic equipment. However, the production of new equipment has a significant impact on the natural environment and a relatively high consumption of natural resources. To address these issues, the circular economy has been implemented in recent years by promoting and introducing numerous measures to facilitate the recycling...
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In vitro biological evaluation of a novel folic acid-targeted receptor quantum dot−β−cyclodextrin carrier for C-2028 unsymmetrical bisacridine in the treatment of human lung and prostate cancers
PublicationTraditional small-molecule chemotherapeutics usually do not distinguish tumors from healthy tissues. However, nanotechnology creates nanocarriers that selectively deliver drugs to their site of action. This work is the next step in the development of the quantum dot−β−cyclodextrin−folic acid (QD−β−CD−FA) platform for targeted and selected delivery of C−2028 unsymmetrical bisacridine in cancer therapy.Herein, we report an initial...
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Development and validation of lumbar spine finite element model
PublicationThe functional biomechanics of the lumbar spine have been better understood by finite element method (FEM) simulations. However, there are still areas where the behavior of soft tissues can be better modeled or described in a different way. The purpose of this research is to develop and validate a lumbar spine section intended for biomechanical research. A FE model of the 50th percentile adult male (AM) Total Human Model for Safety...
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New Trends in Sample Preparation Techniques for the Analysis of the Residues of Pharmaceuticals in Environmental Samples
PublicationPharmaceutical residues in the environment is a field of special interest due to the adverse effects to either human health or aquatic and soil environment. Pharmaceuticals have been already detected in underground, surface and wastewaters, soils, manure and sediments. The growing awareness of environmental pollution arising from human activity forces the need for their comprehensive determination. Environmental samples are complex...
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The Chernobyl effect
PublicationThe 1986 Chernobyl catastrophe was not only a human and ecological disaster, but also a political-ideological one, severely discrediting Soviet governance and galvanizing dissidents in the Eastern Bloc. In the case of Poland, what began as isolated protests against the Soviet nuclear site grew to encompass domestic nuclear projects in general, and in the process spread across the country and attracted new segments of society. This...
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Validated GC–MS method for determination of bisphenol a and its five analogues in dietary and nutritional supplements
PublicationBisphenol A (BPA) and its analogues showing structural and functional similarity to BPA are commonly applied in various industrial applications and thus are becoming ubiquitous in the environment. At the same time there is increasing scientific evidence that exposure to these chemicals may lead to adverse health effects in human and wildlife. In recent years dietary and nutritional supplements dedicated for athletes have become...
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The role of ergonomics in architectonic and marketing operations
PublicationThe 20th century, along with the development of mass culture, brought a rapid increase of marketing communications significance. At first, this branch of art had an informational function associated with advertising operations. Nowadays, an increase of marketing specialists’ interest in influencing a human being by the space they stay in may be observed. Ergonomics plays an important role in such operations. The aim of this article...
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Evolution of End-User Participation in IT Projects.
PublicationThis chapter is aimed at presenting a review of evolutionary design paradigms which determine the end-user’s role in IT (Information Technology) projects across recent decades. This review covers different perspectives starting from technology-oriented sequential software development lifecycles, through user-centred approaches, ending finally in contemporary service design approaches supported by e-business and social media. Finally,...
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In search of a new relationship between nature and society
PublicationWe live in an era of breakthrough- not only in the literal sense of the word, but the breakthrough of the century or the millennium. New discoveries and the crisis present in the economy, society, religion and ecology forces a review of all universally accepted theories. Nature, ecology and environment are the key words used in every area of human activity. It has led to the development of a new scientific field- the philosophy...
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Virtual reality as a tool for development and simulation. Research projects and experience of the Gdańsk University of Technology
PublicationBy supporting the human imagination, virtual reality technology can be applied in almost every human activity. This is evidenced by the cooperation of the Immersive 3D Visualization Lab with specialists representing such different professions from architects and artists, astronomers and chemists, through historians and museologists, criminologists and military educators, mechanical and ship engineers, up to physicians and psychologists....
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Biometryczna kontrola dostępu
PublicationOpisano szczegółowo algorytm detekcji oraz identyfikacji człowieka na podstawie punktów nodalnych twarzy. Zdefiniowano pojęcia: biometria, proces pomiaru biometrycznego, metody biometrycznej identyfikacji oraz kontrola dostępu. Przedstawiono opis opracowanego systemu biometrycznej identyfikacji wykorzystującego sztuczne sieci neuronowe. Podano wyniki badań oraz przeprowadzono ich wnikliwą dyskusję.Biometrics is the study of automated...
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Cognitive motivations and foundations for building intelligent decision-making systems
PublicationConcepts based on psychology fit well with current research trends related to robotics and artificial intelligence. Biology-inspired cognitive architectures are extremely useful in building agents and robots, and this is one of the most important challenges of modern science. Therefore, the widely viewed and far-reaching goal of systems research and engineering is virtual agents and autonomous robots that mimic human behavior in...
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Specific detection of Alternaria alternata by PCR and real-time PCR
PublicationFungi of Alternaria genus are cosmopolitan organisms, which spores can be found in the air, soil, water, clothing and food. They commonly occur as saprotrophs on the plant remains, contributing to the decomposition of organic matter. Additionally, they are components of the normal human and animal skin flora. Alternaria spp. are also known human allergens, causing hay fever and allergic reactions that can lead to the development...
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Birds' feathers – Suitable samples for determination of environmental pollutants
PublicationThe intensive development of industry and human population results in large amounts of different xenobiotic emitted into individual ecosystem components. As a consequence, monitoring of the level of pollution of particular elements of the environment by exotoxins has become a common interest. The determination of environmental changes by different types of biological indicators is called bioindication, which is used as one of the...
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Koncepcja analizy stanów emocjonalnych użytkowników w kontekście systemów zabezpieczeń transportowych
PublicationAutorzy, przywołując własne i światowe badania nad rozpoznawaniem emocji ludzkich z obrazu twarzy, wskazują na możliwość zastosowania algorytmów komputerowych i ich implementacji w komputerach osobistych (i innych urządzeniach personalnych wyposażonych w dostatecznie silny procesor obliczeniowy). Zastosowanie takiego rozwiązania może poprawić bezpieczeństwo użytkowania urządzeń, maszyn i pojazdów, których operatorzy muszą gwarantować...
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Borders of Digital Art in the Context of the Information Society
PublicationThe article shows the relationship between the development of information technologies, the characteristics of the information society and digital art. The broad possibilities of the digital world related to recording, storing and processing data (cyber text, big data, smart services) and the creation of virtual worlds are pointed out. The influence of the development of information technologies on the character of the works of...