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Search results for: GENRE RECOGNITION
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Keratinocyte-derived small extracellular vesicles supply antigens for CD1a-resticted T cells and promote their type 2 bias in the context of filaggrin insufficiency
PublicationIntroduction: Exosome-enriched small extracellular vesicles (sEVs) are nanosized organelles known to participate in long distance communication between cells, including in the skin. Atopic dermatitis (AD) is a chronic inflammatory skin disease for which filaggrin (FLG) gene mutations are the strongest genetic risk factor. Filaggrin insufficiency affects multiple cellular function, but it is unclear if sEV-mediated cellular communication...
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Drug-resistant and hospital-associated Enterococcus faecium from wastewater, riverine estuary and anthropogenically impacted marine catchment basin.
PublicationEnterococci, ubiquitous colonizers of humans and other animals, play an increasingly important role in health-care associated infections (HAIs). Acquisition of resistance determinants not only seriously limits available therapeutic options but also increases available gene pool for other species. It is believed that the recent evolution of two clinically relevant species, Enterococcus faecalis and Enterococcus faecium occurred...
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Sequence-dependent structural properties of B-DNA: what have we learned in 40 years?
PublicationThe structure of B-DNA, the physiological form of the DNA molecule, has been a central topic in biology, chemistry and physics. Far from uniform and rigid, the double helix was revealed as a flexible and structurally polymorphic molecule. Conformational changes that lead to local and global changes in the helix geometry are mediated by a complex choreography of base and backbone rearrangements affecting the ability of the B-DNA...
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Poloxamer: A versatile tri-block copolymer for biomedical applications
PublicationPoloxamers, also called Pluronic, belong to a unique class of synthetic tri-block copolymers containing central hydrophobic chains of poly(propylene oxide) sandwiched between two hydrophilic chains of poly(ethylene oxide). Some chemical characteristics of poloxamers such as temperature-dependent self-assembly and thermo-reversible behavior along with biocompatibility and physiochemical properties make poloxamer-based biomaterials...
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“Shadow” vs. “Phase 3D” method within endoscopic examinations of marine engines
PublicationA visual investigation of surfaces creating internal, working spaces of marine combustion engines by means of specialized view-finders so called endoscopes is at present almost a basic method of technical diag-nostics. The surface structure of constructional material is visible during investigations like through the magnifying glass (usually with a precisely determined magnification), which makes possible a detection, recognition...
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Myrosinase activity in different plant samples; optimisation of measurement conditions for spectrophotometric and pH-stat methods
PublicationMyrosinase found in Brassicaceae plants, is the enzyme responsible for hydrolysis of glucosinolates. As a result a variety of biologically active metabolites are liberated, whose importance in crop protection and especially in cancer chemoprevention is rapidly gaining recognition. The growing practical application of glucosinolate degradation products requires that sensitive and reliable methods of myrosinase activity determination...
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Visual Features for Endoscopic Bleeding Detection
PublicationAims: To define a set of high-level visual features of endoscopic bleeding and evaluate their capabilities for potential use in automatic bleeding detection. Study Design: Experimental study. Place and Duration of Study: Department of Computer Architecture, Faculty of Electronics, Telecommunications and Informatics, Gdansk University of Technology, between March 2014 and May 2014. Methodology: The features have...
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Molecularly imprinted polymers for the detection of volatile biomarkers
PublicationIn the field of cancer detection, the development of affordable, quick, and user-friendly sensors capable of detecting various cancer biomarkers, including those for lung cancer (LC), holds utmost significance. Sensors are expected to play a crucial role in the early-stage diagnosis of various diseases. Among the range of options, sensors emerge as particularly appealing for the diagnosis of various diseases, owing to their cost-effectiveness,...
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Determination of long-chain aldehydes using a novel quartz crystal microbalance sensor based on a biomimetic peptide
PublicationThere is an increasingly popular trend aimed at improvement of fundamental metrological parameters of sensors via implementation of materials mimicking biological olfactory systems. This study presents investigation on usefulness of the peptide mimicking HarmOBP7 region as a receptor element of the piezoelectric sensor for selective analysis of long-chain aldehydes. Identification of odorant binding proteins creates new possibilities...
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A framework for Air Quality Management Zones - Useful GIS-based tool for urban planning: Case studies in Antwerp and Gdańsk
PublicationThere is a growing recognition of the importance of proper urban design in the improvement of air flow and pollution dispersion and in reducing human exposure to air pollution. However, a limited number of studies have been published so far focusing on the development of standard procedures which could be applied by urban planners to effectively evaluate urban conditions with respect to air quality. To fill this gap, a new approach...
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Thermal Image Processing for Respiratory Estimation from Cubical Data with Expandable Depth
PublicationAs healthcare costs continue to rise, finding affordable and non-invasive ways to monitor vital signs is increasingly important. One of the key metrics for assessing overall health and identifying potential issues early on is respiratory rate (RR). Most of the existing methods require multiple steps that consist of image and signal processing. This might be difficult to deploy on edge devices that often do not have specialized...
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Activation of Metabotropic Glutamate Receptor (mGlu2) and Muscarinic Receptors (M1, M4, and M5), Alone or in Combination, and Its Impact on the Acquisition and Retention of Learning in the Morris Water Maze, NMDA Expression and cGMP Synthesis
PublicationThe Morris water maze (MWM) is regarded as one of the most popular tests for detecting spatial memory in rodents. Long-term potentiation and cGMP synthesis seem to be among the crucial factors involved in this type of learning. Muscarinic (M1, M4, and M5 receptors) and metabotropic glutamate (mGlu) receptors are important targets in the search for antipsychotic drugs with the potency to treat cognitive disabilities associated with...
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The energy concept of money
PublicationPurpose: This paper aims to provide the literature review seeking an answer whether energy can be used as a universal equivalent instead of money. Methodology: The author conducted a review of available literature and data sources related to the money theory and energy concept of money. Findings: It was found that the definition of energy as a general equivalent has a contextual and dynamic nature, and this field’s consolidation...
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Convolutional Neural Networks for C. Elegans Muscle Age Classification Using Only Self-Learned Features
PublicationNematodes Caenorhabditis elegans (C. elegans) have been used as model organisms in a wide variety of biological studies, especially those intended to obtain a better understanding of aging and age-associated diseases. This paper focuses on automating the analysis of C. elegans imagery to classify the muscle age of nematodes based on the known and well established IICBU dataset. Unlike many modern classification methods, the proposed...
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Genetic programming extension to APF-based monocular human body pose estimation
PublicationNew method of the human body pose estimation based on a single camera 2D observation is presented, aimed at smart surveillance related video analysis and action recognition. It employs 3D model of the human body, and genetic algorithm combined with annealed particle filter for searching the global optimum of model state, best matching the object's 2D observation. Additionally, new motion cost metric is employed, considering current...
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Chemical hazard in glacial melt? The glacial system as a secondary source of POPs (in the Northern Hemisphere). A systematic review
PublicationToxicity of compounds belonging to persistent organic pollutants (POPs) iswidely known, and their re-emission from glaciers has been conclusively demonstrated. However, the harmful effects associated with such secondary emissions have yet to be thoroughly understood, especially in the spatial and temporal context, as the existing literature has a clear sampling biaswith the best recognition of sites in the European Alps. In this...
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Highly selective impedimetric determination of Haemophilus influenzae protein D using maze-like boron-doped carbon nanowall electrodes
PublicationThis study reports a novel impedimetric immunosensor for protein D detection in purified and bacterial (Haemophilus influenzae, Hi) samples. The detection was based on antigen recognition by anti-protein D antibodies (apD) immobilised at the maze-like boron-doped carbon nanowall electrodes (B:CNW). The B:CNW electrodes were synthesised, and their surface was characterised by scanning electron microscopy (SEM) and X-ray photoelectron...
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Potentiometric sensor containing set of ion selective electrodes with lipid modified membranes for quality assessment of tested non-alcoholic beverages
PublicationPotentiometric sensors may be a good tool for fast quality control of commercial drinks. In this work, such a sensor, containing a set of ion-selective electrodes with lipid-modified membranes (benzylhexadecyldimethylammonium chloride monohydrate, hexadecylamine, 1-dodecanol, elaidic acid, cholesterol) was used for discrimination and quality control of non-alcoholic beverages, mainly composed of sugar and citric acid. It was found...
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Fully Automated AI-powered Contactless Cough Detection based on Pixel Value Dynamics Occurring within Facial Regions
PublicationIncreased interest in non-contact evaluation of the health state has led to higher expectations for delivering automated and reliable solutions that can be conveniently used during daily activities. Although some solutions for cough detection exist, they suffer from a series of limitations. Some of them rely on gesture or body pose recognition, which might not be possible in cases of occlusions, closer camera distances or impediments...
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Using Convolutional Neural Networks for Corneal Arcus Detection Towards Familial Hypercholesterolemia Screening
PublicationFamilial hypercholesterolemia (FH) is a highly undiagnosed disease. Among FH patients, the onset of premature coronary artery disease is 13 times higher than in the general population. Early diagnosis and treatment is essential to prevent cardiovascular diseases and their complications, and to prolong life. One of the clinical criteria of FH is the occurrence of a corneal arcus (CA) among patients, especially those under 45 years...
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The Bridge to Knowledge – Open Access to Scientific Research Results on Multidisciplinary Open System Transferring Knowledge Platform
PublicationThe European policy of Open Access to scientific research is now one of the key issues discussed in public debates on the future development of scientific communication. The implementation of Open Access tools has significant impact on scientific and economic growth. On the one hand, Open Access accelerates disseminating new research findings and facilitates recognition of authors on a more global scale. On the other hand, Open...
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Deep CNN based decision support system for detection and assessing the stage of diabetic retinopathy
PublicationThe diabetic retinopathy is a disease caused by long-standing diabetes. Lack of effective treatment can lead to vision impairment and even irreversible blindness. The disease can be diagnosed by examining digital color fundus photographs of retina. In this paper we propose deep learning approach to automated diabetic retinopathy screening. Deep convolutional neural networks (CNN) - the most popular kind of deep learning algorithms...
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Progressing Pollutant Elution from Snowpack and Evolution of its Physicochemical Properties During Melting Period— a Case Study From the Sudetes, Poland
PublicationMain aim of the work assumed recognition of physicochemical changes in snowpack occurring during the melting period. Properties of snow cover had been identified at two sites in Western Sudetes mountains (860 and 1228 m asl) in SW Poland since the end of January, and monitored until the disappearance of snow in late Spring. Snow pit measurements and sample collection at both sites were made followed by chemical analyses with the...
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The optimisation of analytical parameters for routine profiling of antioxidants in complex mixture by HPLC coupled post-column derivatisation
PublicationIntroduction: The wide application of natural and artificial antioxidants in food, cosmetic and pharmaceutical industry as well as the recognition of the importance of food antioxidants for supporting human health created demand for reliable and industrially applicable methods of determining antioxidative activity. This requirement can be fullfilled with the recently proposed HPLC-post-column derivatisation approach enabling the...
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Information retrieval with semantic memory model
PublicationPsycholinguistic theories of semantic memory form the basis of understanding of natural language concepts. These theories are used here as an inspiration for implementing a computational model of semantic memory in the form of semantic network. Combining this network with a vector-based object-relation-feature value representation of concepts that includes also weights for confidence and support, allows for recognition of concepts...
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Interdisciplinary research as a form of monument protection and preparation for the investment process on the example of the former Gdańsk Shipyard complex
PublicationThe multi-layered heritage of many industrial plants operating until the end of the 20th century creates a particular challenge for conservators, designers and investors. In the process of protecting its values, displaying qualities and managing the property, it is necessary to recognize a wider transformation of technology of the entire plant and the individual functions of its buildings, as well as the context of intangible...
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Psychological and physical components in forming preferences on urban greenery management – The case of trees
PublicationPublic opinion is increasingly important in managing urban greenery. In this regard, this study demonstrates the importance of sociological (environmental worldviews), psychological (place attachment, perceived benefits of trees), and physical factors (type of building people live in, and urban greenery) in forming residents’ opinions on whether the municipality or landowners should decide about tree removal on private land. Logistic...
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Recent advancements in molecularly imprinted polymers for the removal of heavy metal ions and dyes
PublicationContamination set off by highly toxic metal ions and dyes is a big threat to the environment and living beings. Various industries like metal plating, mining, pesticides, battery manufacturing, and dyeing release metal ions and toxic dyes directly into the water. It is necessary to remove these toxic substances from the environment. Molecular imprinting technology (MIT) got a lot of attention in the last two decades because of...
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Usługi ośrodków podregionalnych w Polsce
PublicationOśrodki podregionalne definiowane są jako miasta, w których skoncentrowane są takie usługi, które w Polsce mogą być w kilku miastach województwa, ale nie w każdym mieście powiatowym. Usługi zawsze miały tendencję do koncentracji, tworząc ośrodki różnych poziomów w hierarchicznej sieci osadniczej. Celem prezentowanych badań było: (1) określenie usług typowych dla poziomu podregionalnego; (2) rozpoznanie koncentracji tych usług,...
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Międzymiasto: Nowa formuła ładu przestrzennego trefy podmiejskiej
Publication.
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Rewitalizacja dróg wodnych delty Wisły jako podstawa nowej perspektywy osiedleńczej
PublicationW artykule opisano badania dotyczące rewitalizacji dróg wodnych Delty Wisły. Problematyka badawcza dotyczy rozwoju obszaru na styku lądu i wody. Wpływ lokalizacji nadmorskiej, i związana z nią problematyka wynikająca z położenia poniżej poziomu morza są dostrzegalne nawet do stu kilometrów od wybrzeża. Dodatkowym aspektem, który ujemnie wpływa na rozwój obszaru delty po II wojnie światowej jest utrata tożsamości regionalnej. Dlatego...
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Molecularly targeted nanoparticles: an emerging tool for evaluation of expression of the receptor for advanced glycation end products in a murine model of peripheral artery disease
PublicationAbstract Background: Molecular imaging with molecularly targeted probes is a powerful tool for studying the spatio-temporal interactions between complex biological processes. The pivotal role of the receptor for advanced glycation end products (RAGE) in numerous pathological processes, aroused the demand for RAGE targeted imaging in various diseases. In the study, we evaluated the use of a diagnostic imaging agent for RAGE quantification...
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Why Are Left-Handed G-Quadruplexes Scarce?
PublicationG-quadruplexes (G4s) are nucleic acid structures crucial for the regulation of gene expression and genome maintenance. While they hold promise as nanodevice components, achieving desired G4 folds requires understanding the interplay between stability and structural properties, like helicity. Although right-handed G4 structures dominate the experimental data, the molecular basis for this preference over left-handed helicity is unclear....
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Customizing nano-chitosan for sustainable drug delivery
PublicationChitosan is a natural polymer with acceptable biocompatibility, biodegradability, and mechanical stability; hence, it has been widely appraised for drug and gene delivery applications. However, there has been no comprehensive assessment to tailor-make chitosan cross-linkers of various types and functionalities as well as complex chitosan-based semi- and full-interpenetrating networks for drug delivery systems (DDSs). Herein, various...
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Pathogenesis of psoriasis in the “omic” era. Part III. Metabolic disorders, metabolomics, nutrigenomics in psoriasis
PublicationPsoriasis is a systemic disease that is strictly connected with metabolic disorders (insulin resistance, atherogenic dyslipidemia, arterial hypertension, and cardiovascular diseases). It occurs more often in patients with a more severe course of the disease. Obesity is specially an independent risk factor and it is associated with a worse treatment outcome because of the high inflammatory activity of visceral fatty tissue and...
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A breath of fresh air - social cognitive career theory in studying entrepreneurial intentions
PublicationA pinch of robustness and a pinch of freshness create an interesting story. That is why this study focuses on entrepreneurial intentions from an alternative theoretical perspective in an underexplored context. In this paper, it is argued that social cognitive career theory is relevant to the study of individual entrepreneurial cognition and behaviour, and it offers a solid framework in entrepreneurship research. This paper expands...
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Identifying and Mitigating the Negative Effects of Power in Organizations
PublicationThis article investigates the possible negative effects of power in organizations. It demonstrates how holding power may affect an individual’s perception of others, actions, and cognition. Ways in which power may have a detrimental effect on different aspects of a manager’s functioning within an organization, including building relationships, communication, and performance are analyzed. It is argued that individuals are unaware...
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The biological role of prolyl oligopeptidase and the procognitive potential of its peptidic inhibitors from food proteins
PublicationProlyl oligopeptidase (POP) is a conserved serine protease belonging to proline-specific peptidases. It has both enzymatic and non-enzymatic activity and is involved in numerous biological processes in the human body, playing a role in e.g., cellular growth and differentiation, inflammation, as well as the development of some neurodegenerative and neuropsychiatric disorders. This article describes the physiological and pathological...
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Time-frequency analysis in optical coherence tomography for technical objects examination
PublicationOptical coherence tomography (OCT) is one of the most advanced optical measurement techniques for complex structure visualization. The advantages of OCT have been used for surface and subsurface defect detection in composite materials, polymers, ceramics, non-metallic protective coatings, and many more. Our research activity has been focused on timefrequency spectroscopic analysis in OCT. It is based on time resolved spectral analysis...
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Serotonergic–Muscarinic Interaction within the Prefrontal Cortex as a Novel Target to Reverse Schizophrenia-Related Cognitive Symptoms
PublicationRecent studies revealed that the activation of serotonergic 5-HT1A and muscarinic M1, M4, or M5 receptors prevent MK-801-induced cognitive impairments in animal models. In the present study, the effectiveness of the simultaneous activation of 5-HT1A and muscarinic receptors at preventing MK-801-induced cognitive deficits in novel object recognition (NOR) or Y-maze tests was investigated. Activators of 5-HT1A (F15599), M1 (VU0357017),...
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Intracranial hemorrhage detection in 3D computed tomography images using a bi-directional long short-term memory network-based modified genetic algorithm
PublicationIntroduction: Intracranial hemorrhage detection in 3D Computed Tomography (CT) brain images has gained more attention in the research community. The major issue to deal with the 3D CT brain images is scarce and hard to obtain the labelled data with better recognition results. Methods: To overcome the aforementioned problem, a new model has been implemented in this research manuscript. After acquiring the images from the Radiological...
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How do responsible universities perceive their social engagement? In search of signs of Creating Shared Value by the University
PublicationObjectives: University social responsibility still lacks legitimisation and is perceived as a burden that hinders academics from doing research and teaching. Creating Shared Value by the University may serve as a tool to motivate universities to engage in initiatives for society, as this is beneficial for both parties. Yet, some researchers perceive the creation of economic value as inappropriate for academia. Thus, it was interesting...
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Detecting Apples in the Wild: Potential for Harvest Quantity Estimation
PublicationKnowing the exact number of fruits and trees helps farmers to make better decisions in their orchard production management. The current practice of crop estimation practice often involves manual counting of fruits (before harvesting), which is an extremely time-consuming and costly process. Additionally, this is not practicable for large orchards. Thanks to the changes that have taken place in recent years in the field of image...
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Advanced polarization sensitive analysis in optical coherence tomography
PublicationThe optical coherence tomography (OCT) is an optical imaging method, which is widely applied in variety applications. This technology is used to cross-sectional or surface imaging with high resolution in non-contact and non-destructive way. OCT is very useful in medical applications like ophthalmology, dermatology or dentistry, as well as beyond biomedical fields like stress mapping in polymers or protective coatings defects detection....
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Modernization of historic healthcare buildings
PublicationThe practice of transforming and adapting the existing healthcare facilities to meet the growing demands of modern medicine applies not only to buildings of historical value. Of course, one can set a time point from which hospitals, erected mostly with industrialized technologies, undergo upgrades for better or worse effect. Existing healthcare buildings or facilities, including historic ones, have to be refurbished and adapted...
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Blood concentrations of a new psychoactive substance 4-chloromethcathinone (4-CMC) determined in 15 forensic cases
PublicationPurpose: The 4-chloromethcathinone (4-CMC) is a synthetic derivative of cathinone and belongs to new psychoactive substances. Neither data on the effects of 4-CMC on the human body, nor on nontoxic, toxic and lethal concentrations in biological materials have been published in the literature. This paper describes the results of an analysis of the blood concentrations of 4-CMC determined in 15 forensic cases related to nonfatal...
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DIAGNOSIS OF MALIGNANT MELANOMA BY NEURAL NETWORK ENSEMBLE-BASED SYSTEM UTILISING HAND-CRAFTED SKIN LESION FEATURES
PublicationMalignant melanomas are the most deadly type of skin cancer but detected early have high chances for successful treatment. In the last twenty years, the interest of automated melanoma recognition detection and classification dynamically increased partially because of public datasets appearing with dermatoscopic images of skin lesions. Automated computer-aided skin cancer detection in dermatoscopic images is a very challenging task...
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Marking the Allophones Boundaries Based on the DTW Algorithm
PublicationThe paper presents an approach to marking the boundaries of allophones in the speech signal based on the Dynamic Time Warping (DTW) algorithm. Setting and marking of allophones boundaries in continuous speech is a difficult issue due to the mutual influence of adjacent phonemes on each other. It is this neighborhood on the one hand that creates variants of phonemes that is allophones, and on the other hand it affects that the border...
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Modeling the Customer’s Contextual Expectations Based on Latent Semantic Analysis Algorithms
PublicationNowadays, in the age of Internet, access to open data detects the huge possibilities for information retrieval. More and more often we hear about the concept of open data which is unrestricted access, in addition to reuse and analysis by external institutions, organizations and people. It’s such information that can be freely processed, add another data (so-called remix) and then published. More and more data are available in text...
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Molecular dynamics simulations reveal the balance of forces governing the formation of a guanine tetrad—a common structural unit of G-quadruplex DNA
PublicationG-quadruplexes (G4) are nucleic acid conformations of guanine-rich sequences, in which guanines are arranged in the square-planar G-tetrads, stacked on one another. G4 motifs form in vivo and are implicated in regulation of such processes as gene expression and chromosome maintenance. The structure and stability of various G4 topologies were determined experimentally; however, the driving forces for their formation are not fully...