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Percepcja jakości usług zdrowotnych w ujęciu relacyjnym
PublikacjaW artykule zostały zaprezentowane podstawowe aspekty dotyczące jakości usług zdrowotnych. Autor odniósł się do głównych grup interesariuszy tego typu usług, a nastepnie zaprezentował model powiązań pomiędzy tego typu grupami a pacjentem. Zaprezentowane zostały także badania związane z głównymi determinantami jakości usług zdrowotnych w percepcji pacjentów, odnosząc się jednocześnie do ich oczekiwań względem poszczególnych grup...
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Diaryl Sulfide Derivatives as Potential Iron Corrosion Inhibitors: A Computational Study
PublikacjaThe present work aimed to assess six diaryl sulfide derivatives as potential corrosion inhibitors. These derivatives were compared with dapsone (4,4′-diaminodiphenyl sulfone), a common leprosy antibiotic that has been shown to resist the corrosion of mild steel in acidic media with a corrosion efficiency exceeding 90%. Since all the studied compounds possess a common molecular backbone (diphenyl sulfide), dapsone was taken as the...
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ROYAL CHAPEL IN GDANSK. STUDY OF FACILITY INVENTORY WITH THE USAGE OF LASER SCANNING WITHIN THE FRAMES OF STUDENT PROJECT
PublikacjaThis article presents the photogrammetric works carried out during the architectural inventory of the Royal Chapel in the Main Town of Gdansk (Poland). The facility has the status of a monument of architecture and since decades it is covered by geodetic monitoring, realized with the participation of the Department of Geodesy of Faculty of Civil and Environmental Engineering of Gdańsk University of Technology . For several years,...
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Products of Photo- and Thermochemical Rearrangement of 19-Membered di-tert-Butyl-Azoxybenzocrown
PublikacjaThe preparation and characterization of products of the photochemical and thermochemical rearrangements of 19-membered azoxybenzocrowns with two, bulky, tert-butyl substituents in benzene rings in the para positions to oligooxyethylene fragments (meta positions to azoxy group, i.e., t-Bu-19-Azo-O have been presented. In photochemical rearrangement, two colored typical products were expected, i.e., 19-membered o-hydroxy-m,m′-di-tert-butyl-azobenzocrown...
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Aktualne zagadnienia stosowania kanalizacyjnej studzienki rewizyjnej. Cz. III
PublikacjaZagadnienia szczególnych wymagań charakterystycznych dla grup konstrukcji. Problemy, konsekwencje. Charakterystyczne przykłady awarii.
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Motyw autonomii a oczekiwany i faktyczny poziom satysfakcji z prowadzenia działalności gospodarczej
PublikacjaMotyw autonomii jest niejednokrotnie wskazywany jako jeden z istotniejszych czynników skłaniających ludzi do założenia własnej działalności gospodarczej, choć nie dla każdego przedsiębiorcy jest równie ważny. W opracowaniu zaprezentowano wyniki badań przeprowadzonych w grupie początkujących przedsiębiorców. Osoby deklarujące kierowanie się motywem autonomii oczekiwały, że uzyskają wyższy poziom satysfakcji po roku prowadzenia działalności...
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Nietypowe próbne obciążenia pali prefabrykowanych
PublikacjaOsiadanie grup palowych wciąż stanowi problem naukowy i inżynierski. Dotyczy to również małych grup palowych, dla pali usytuowanych w jednym rzędzie. W pracy przedstawiono wyniki próbnych obciążeń statycznych dwóch pali. W programie badawczym wykonano testy dla obu pali łącznie oraz oddzielnie. Różna charakterystyka krzywych osiadania wymaga dalszych weryfikacji przy uwzględnieniu zmiennych parametrów geotechnicznych i geometrycznych.
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Badanie stabilności prepolimerów estrouretanowych
PublikacjaPrepolimery estrouretanowe otrzymywano na podstawie oligoeestrolu ("Poles 55/20) i użytego w nadmiarze 4,4-iizocyjanianodifenylometanu. Określono wpływ szybkości obrotów trzpienia wiskozymetru, temperatury, procentowej zawartości grup NCO na wartości lepkości tych produktów. Oceniono stabilność prepolimerów w toku przechowywania w ciągu 4 tygodni (zmiana zawartości grup NCO). Budowę chemiczną uzyskanych prepolimerów ustalono...
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Glucosinolates from lepidium peruvianum as potential antiamnestic drugs
PublikacjaLepidium peruvianum (maca) (Brassicaceae) is a naturally occurring plant mainly in the high Andes of Peru. In recent years, it has been intensively researched in terms of its influence on various diseases and towards health improvement. Alzheimer’s disease is an incurable disease that most often affects adults over the age of 60. As since 2003 the US Food and Drug Administration (FDA) did not approve any new drug for Alzheimer’s...
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Raman spectroscopic investigation of blood and related materials
PublikacjaThis paper reports preliminary studies on use of Raman spectroscopy for investigation of blood. High quality blood spectra were recorded in-vitro with excitation wavelengths of 830 nm. Because of complex composition of the blood as well as by light attenuation and scattering in the tissues, spectra set up from wide, low-intensive Raman bands and intensive optical background. To get information about origin of bands in Raman spectra...
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The atherosclerotic heart disease and protecting properties of garlic: contemporary data
PublikacjaArtykuł jest pracą przeglądową zawierającą najnowsze dane dotyczące choroby serca w przebiegu miażdżycowym oraz ochonnych właściwości czosnku. Obecnie prowadzone badania wykazały fundamentalną rolę jaką odgrywa czosnek we wszystkich stadiach choroby. Liczne badania in-vitro potwierdzają zdolność czosnku do redukcji parametrów zachorowania na choroby serca w przebiegu miażdżycy: całkowity cholesterol, LDL, trigliceryny, utlenione...
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Pre-clinical evaluation of 1-nitroacridine derived chemotherapeutic agent that has preferential cytotoxic activity towards prostate cancer
PublikacjaPraca zawiera wyniki badań przedklinicznych pochodnej 1-nitroakrydyny C-1748 wobec komórek ludzkiego raka prostaty CaP in vitro, jak i przeszczepialnego na zwierzęta. W oparciu o fosforylację histonu H2AX jako markera podwójnych cięć DNA wykazano, że C-1748 jest bardziej aktywny w komórkach CaP niż HL60. Zidentyfikowano poza tym receptor androgenny (AR) jako cel molekularny badanego związku. W doświadczeniach na zwierzętach stwierdzono...
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Gold nanoparticles and their coatings, their effect on cells and their interaction with radiation
PublikacjaTwo nanometre gold nanoparticles (AuNPs), bearing sugar moieties and/or polyethylene glycolamine (PEG-amine), were synthesised and evaluated for their in vitro toxicity and ability to radiosensitise cells with 220 kV and 6 MV X-rays, using four cell lines representing normal and cancerous skin and breast tissues. In addition to the observed intrinsic cancer-selective chemotoxicity, these AuNPs acted as radiosensitisers in combination with...
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Immunosuppressive properties of amino acid and peptide derivatives of mycophenolic acid
PublikacjaMycophenolic acid (MPA) was coupled with amino acids and biologically active peptides including derivatives of tuftsin to modify its immunosuppressive properties. Both amino acid unit in the case of simple MPA amides and modifications within peptide moiety of MPA - tuftsin conjugates influenced the observed activity. Antiproliferative potential of the obtained conjugates was investigated in vitro and MPA amides with threonine methyl...
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Computational intelligence methods in production management
PublikacjaThis chapter presents a survey of selected computational intelligence methods used in production management. This group of methods includes, among others, approaches based on the artificial neural networks, the evolutionary algorithms, the fuzzy logic systems and the particle swarm optimization mechanisms. From the abovementioned methods particularly noteworthy are the evolutionary and the particle swarm algorithms, which are successfully...
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Emotion Recognition Based on Facial Expressions of Gamers
PublikacjaThis article presents an approach to emotion recognition based on facial expressions of gamers. With application of certain methods crucial features of an analyzed face like eyebrows' shape, eyes and mouth width, height were extracted. Afterwards a group of artificial intelligence methods was applied to classify a given feature set as one of the following emotions: happiness, sadness, anger and fear. The approach presented in this...
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Emotion Recognition Based on Facial Expressions of Gamers
PublikacjaThis article presents an approach to emotion recognition based on facial expressions of gamers. With application of certain methods crucial features of an analysed face like eyebrows' shape, eyes and mouth width, height were extracted. Afterwards a group of artificial intelligence methods was applied to classify a given feature set as one of the following emotions: happiness, sadness, anger and fear.The approach presented in this...
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Using phase of short-term Fourier transform for evaluation of spectrogram performance
PublikacjaThe concept of spectrogram performance evaluation which exploits information on phase of short-term Fourier transform (STFT) is presented. A spectrograph which is time-frequency analyzing tool, is compared to a filter bank that demultiplexes a signal. Local group delay (LGD) and channelized instantaneous frequency (CIF) is obtained for each filtered component signal. In presented solution the performance is evaluated using so-called...
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The homometallic warwickite V 2 OBO 3
PublikacjaThe synthesis, structure and elementary magnetic characterization of the homometallic warwickite V2OBO3 are reported. The material adopts the orthorhombic warwickite structure type at room temperature, space group Pnma (No. 62) with lattice parameters a = 9.2317(1) Å, b = 3.1172(1) Å, and c = 9.5313(1) Å. Temperature-dependent magnetic susceptibility, electrical resistivity, and specific heat measurements show anomalies near 35 K,...
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Badanie stabilności chemicznej prepolimerów etero-uretanowych
PublikacjaPrepolimery eterouretanowe otrzymywano na podstawie oligoeterolu (Rokopolu D2002 lub PTMG 1000) i użytego w nadmiarze 4,4-diizocyjanianodifenylometanu. Określono wpływ szybkości obrotów trzpienia wiskozymetru, temperatury, procentowej zawartości grup NCOoraz rodzaju użytego oligoeterolu na lepkość otrzymanych produktów. Oceniono stabilność omawianych prepolimerów w toku przechowywania ich w ciągu 4 tygodni (zmiana zawartości...
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Deposition and characterization of organic polymer thin films using a dielectric barrier discharge with different C2Hm/N2 (m = 2, 4, 6) gas mixtures
PublikacjaOrganic polymer thin films have been deposited on Si(100) and aluminum coated glass substrates by a dielectric barrier discharge (DBD) operated at medium pressure using different C2Hm/N2 (m = 2, 4, 6) gas mixtures. The deposited films were characterized by various spectroscopic techniques. Fourier transform infrared reflection absorption spectroscopy (FT-IRRAS) revealed the chemical functional groups present in the films. The surface...
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Electrochemical synthesis and characterization of nanocomposites based on poly(3,4-ethylenedioxythiophene) and functionalized carbon nanotubes
PublikacjaThis work is focused on new composite materials consisting of poly(3,4-ethylenedioxythiophene) (pEDOT) and functionalized multi-walled carbon nanotubes synthesized electrochemically. Three types of composites were synthesized: the first one containing carbon nanotubes with carboxyl groups (covalent functionalization), the second one containing oxidized carbon nanotubes ox-MWCNTs (with different oxygen-rich polar groups) (covalent...
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International architectural - urban - landscape design workshops to strengthen students’ education, capabilities and mobility
PublikacjaFive international architectural/urban/landscape workshops in Poland and Portugal between 2011 and 2015 are discussed in this article. The general aims of the workshops were to plan to connect divided city spaces, to harmonise them and make them attractive for different uses. The main task was to create in multicultural groups of students the vision of sustainable development in the context of architecture, urban and landscape...
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Antiproliferative, Antiangiogenic, and Antimetastatic Therapy Response by Mangiferin in a Syngeneic Immunocompetent Colorectal Cancer Mouse Model Involves Changes in Mitochondrial Energy Metabolism
PublikacjaIn spite of the current advances and achievements in cancer treatments, colorectal cancer (CRC) persists as one of the most prevalent and deadly tumor types in both men and women worldwide. Drug resistance, adverse side effects and high rate of angiogenesis, metastasis and tumor relapse remain one of the greatest challenges in long-term management of CRC and urges need for new leads of anticancer drugs. We demonstrate that CRC...
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Synthesis, Chemical Characterization and Multiscale Biological Evaluation of a dimericcRGD Peptide for Targeted Imaging of αVβ3 Integrin Activity
PublikacjaCyclic peptides containing the Arg-Gly-Asp (RGD) sequence have been shown to specifically bind the angiogenesis biomarker α V β3 integrin. We report the synthesis, chemical characterization, and biological evaluation of two novel dimeric cyclic RGD-based molecular probes for the targeted imaging of α V β3 activity (a radiolabeled version, 64Cu-NOTA-PEG4-cRGD2, for PET imaging, and a fluorescent version, FITC-PEG4-cRGD2, for in...
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Conjugates of Ciprofloxacin and Levofloxacin with Cell-Penetrating Peptide Exhibit Antifungal Activity and Mammalian Cytotoxicity
PublikacjaSeven conjugates composed of well-known fluoroquinolone antibacterial agents, ciprofloxacin (CIP) or levofloxacin (LVX), and a cell-penetrating peptide transportan 10 (TP10-NH2) were synthesised. The drugs were covalently bound to the peptide via an amide bond, methylenecarbonyl moiety, or a disulfide bridge. Conjugation of fluoroquinolones to TP10-NH2 resulted in congeners demonstrating antifungal in vitro activity against human...
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Upward convergence patterns in chosen environmental-related SDGs
PublikacjaSustainable development is a challenge facing humanity. EU countries not only strive to reach their specific objectives, but they also work collaboratively towards shared goals. There is a need to balance synergies and compromises to address these objectives effectively. When discussing countries' development and people's well-being, one often focuses on socio-economic development. However, it is crucial not to overlook the environmental...
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Electrical properties and structure of lead-borate glass containing iron ions.
PublikacjaThe ac and dc conductivity in iron–lead-borate glass samples was investigated in the frequency range from 1 mHz to 1 MHz and in the temperature range from 153 K to 423 K. The structure was investigated by the means of atomic force microscopy (AFM) and the crystalline phases (if present) were identified by the means of X-ray diffractometry. Two types of ac electrical behaviour were observed. The first group of glass samples which...
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Evaluation of flavour profiles in e-cigarette refill solutions using gas chromatography–tandem mass spectrometry
PublikacjaMany flavour compounds that are present in e-liquids for e-cigarettes are responsible for specific tastes and smoking sensations for users. Data concerning content and specific types of flavours is often limited and unknown to users. The aim of the research was to define and compare flavour profiles of e-liquids with the same group taste from different manufacturers. Gas chromatography coupled with tandem mass spectrometry (GC–MS/MS)...
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Psychosocial risks associated with the profession of train driver
PublikacjaExcellent competencies as well as a good physical and mental health are required in train drivers’ profession. Despite the changes in the structure of employment the train drivers above 46 years and job tenure longer than 30 years are the largest group. The generation gap is becoming more pronounced, and its fulfilment will not be easy. It is related not only to training of new personnel but also promotion of healthy work environment...
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Soft-mode enhanced type-I superconductivity in LiPd2Ge
PublikacjaThe synthesis, crystal structure, and physical properties (magnetization, resistivity, heat capacity) in combination with theoretical calculations of the electronic structure and phonon properties are reported for intermetallic compounds LiPd2X (X = Si, Ge, and Sn). LeBail refinement of powder x-ray diffraction data confirms that all compounds belong to the Heusler family (space group Fm-3m, No. 225). The lattice parameter increases...
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Chemical Pressure Tuning Magnetism from Pyrochlore to Triangular Lattices
PublikacjaGeometrically frustrated lattices combined with magnetism usually host quantum fluctuations that suppress magnetic orders and generate highly entangled ground states. Three-dimensionally (3D) frustrated magnets generally exist in the diamond and pyrochlore lattices, while two-dimensionally (2D) frustrated geometries contain Kagomé, triangular, and honeycomb lattices. In this work, we reported using chemical pressure to tune the magnetism...
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Grupy producenckie jako beneficjenci restrukturyzacji rynków rolnych
PublikacjaW artykule przedstawiono zagadnienie integracji rynku na przykładzie funkcjonowania grup producenckich na rynkach rolnych, ze szczególnym uwzględnieniem roli producentów zbóż. Grupy producenckie ze względu na swoje zalety są ważnym podmiotem wokół którego można by stworzyć dobrze funkcjonujący system skupu i przechowalnictwa zbóż. Grupy producenckie działając w otoczeniu instytucjonalnym agrobiznesu są w kręgu oddziaływania różnych...
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Authentication of whisky due to its botanical origin and way of production by instrumental analysis and multivariate classification methods
PublikacjaHeadspacemass-spectrometry (HS-MS), mid infrared (MIR) and UV–vis spectroscopywere used to authenticate whisky samples from different origins and ways of production ((Irish, Spanish, Bourbon, TennesseeWhisky and Scotch). The collected spectra were processed with partial least-squares discriminant analysis (PLS-DA) to build the classification models. In all cases the five groups ofwhiskieswere distinguished, but the best resultswere...
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Fatigue strength determination of ship structural joints. Part I - Analytical methods for determining fatigue strength of ship tructures
PublikacjaSpectacular accidents at sea which have happened for a few last years show that hull structures of contemporary sea-going ships are not perfect and must be systematically improved. Fatigue strength is one of the groups of strength problems which affect design of contemporary ship's structures and greatly contribute in their improvement process. In this paper several approaches to estimation of fatigue life of hull structural...
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The Bridge of Data Project Objectives
PublikacjaOpen Research Data (ORD) is one of the emerging trends for researchers across the globe. However, it has to be stressed that the level of implementation and awareness of ORD varies between countries. Many initiatives have been created in Polish scientific institutions to support the process of opening publications. These are mainly Open Access (OA) repositories, implementing the so-called green road of OA. However, only a few universities...
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Recent advances on magnetic carbon-related materials in advanced oxidation processes of emerging pollutants degradation
PublikacjaRecently, carbon-related materials have been proposed to improve the charge separation of the photogenerated carriers in the semiconductor matrices’ and surface properties. Carbon-related materials may act as co-catalysts, enhancing the pollutants adsorption on the surface, improving the charge carriers separation and photocatalyst stability and providing more active centres for photocatalytic reactions. This review summarizes...
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Influence of synthesis conditions on glass formation, structure and thermal properties in the Na 2 O-CaO-P 2 O 5 system doped with Si 3 N 4 and Mg
PublikacjaOxynitride phosphate glasses and glass-ceramics were prepared using new synthesis routes for phosphate glasses. Materials were melted from pre-prepared glass samples in the system Na-Ca-P-O with addition of Mg and/or Si3N4 powders under different preparation conditions. The melting process was conducted at 1000–1500 °C either under air or nitrogen atmosphere to obtain materials with different nitrogen content. Their topography...
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Framework for gamification of specialized subjects within engineering studies
PublikacjaGamification is a relatively new term forged along with the occurrence of new information technology, especially easy access to internet and smartphones. Gamification is a use of game mechanics, to modify the behavior of people in non-games situations to increase the involvement of individuals. The method is based on the pleasure that comes from overcoming the obstacles to reach next achievable level, which consists of challenges,...
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Voriconazole and multidrug resistance in Candida albicans
PublikacjaPorównano aktywność grzybostatyczną in vitro worikonazolu, flukonazolu, ketokonazolu i klotrimazolu wobec opornych na flukonazol szczepów klinicznych Candida albicans oraz rekombinowanych szczepów Saccharomyces cerevisiae eksprymujących jeden z genów kodujących białka oporności wielolekowej (MDR) C. albicans: Cdr1p. Cdr2p lub CaMdr1p. Stwierdzono, że nadekspresja genów MDR czyni komórki drożdżaków mniej wrażliwymi na działanie...
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Initial Report on Numerical Modeling of Blood Flow in Myocardial Bridge Region of Coronary Artery: Concept of Model Validation
PublikacjaThe paper presents a numerical method of blood flow simulation within the coronary artery covered by the myocardial bridge. The myocardial bridge is a congenital coronary abnormality caused by the blood vessel location under one of the heart muscles. In this case, the blood flow within the vessel is partially disturbed which can cause several consequences. The presented numerical simulation allowed us to estimate the blood flow...
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Cluster organization as a form of non-technological innovation
PublikacjaThe paper aims to investigate the relationships that cluster enterprises develop with their environment through participation in cluster organization (CO). The authors report the findings from a qualitative study carried out in the Lubusz Metal Cluster. The main research strategy is case study. An in-depth individual interview was used to collect the data, and qualitative content analysis and coding for its analysis. The study...
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Permeability of sandy soils estimated from particle size distribution and field measurements
PublikacjaAccurate estimation of soil permeability is crucial in many geotechnical applications. Empirical and theoretical equations based on soil particle size distribution (PSD) offer a fast and cheap way for preliminary estimation of permeability in granular soils, however the results obtained from various formulas available in the literature often show significant discrepancies. While several comparative studies on this topic have been...
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Untargeted Lipidomics Reveals Differences in the Lipid Pattern among Clinical Isolates of Staphylococcus aureus Resistant and Sensitive to Antibiotics
PublikacjaStaphylococcus aureus resistance to antibiotics is a significant clinical problem worldwide. In this study, an untargeted lipidomics approach was used to compare the lipid fingerprints of S. aureus clinical isolates that are resistant and sensitive to antibiotics. High-performance liquid chromatography coupled with time-of-flight mass spectrometry was employed to rapidly and comprehensively analyze bacterial lipids. Chemometric...
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High-precision bearing estimation for active sonar with cylindrical array performed by interpolated array transformation
PublikacjaThe article presents a method for improving the accuracy of bearing in multibeam sonar with a cylindrical array. The antenna’s non-linear shape and the resulting non-uniform sampling of the signal in space, mean that known methods of high-resolution spectral analysis cannot be used. In order to apply an algorithm from this group, a linear virtual antenna must be produced. The paper presents a technique of mapping a cylindrical...
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Pomoszcz Ministerstwa Inostrannych del Polszy Armenji, Azerbejdzżany i Gruzji = Polish Development Assistance for Armenia, Azerbaijan and Georgia
PublikacjaGeorgia has been one of the priority areas of development assistance of Polish Ministry of Foreign Affairs from 2004, because it plays a important role in Polish forsign policy in the framework of the Eastern Partnership. The largest amounts of development aid supporting the transformation were allocated for this country. Since founding the Eastern Partnership initiative in 2009 also Azerbaijan and Armenia have been included to...
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Design, synthesis, and molecular docking of new 5-HT reuptake inhibitors based on modified 1,2-dihydrocyclopenta[b] indol-3(4H)-one scaffold
PublikacjaA new group of serotonin reuptake inhibitors containing 1,2-dihydrocyclopenta[b]indol-3(4H)-one scaffoldwas synthesized, starting from indole 5-((1H-indol-3-yl)(1,3-dioxane-4,6-diones as a key intermediates. Following three transformations including intramolecular cyclization and formation of imines, a series of new ligand for human serotonin transporter was obtained. The ability of these ligands to inhibit human TS3 serotonin transporter...
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DEEP CONVOLUTIONAL NEURAL NETWORKS AS A DECISION SUPPORT TOOL IN MEDICAL PROBLEMS – MALIGNANT MELANOMA CASE STUDY
PublikacjaThe paper presents utilization of one of the latest tool from the group of Machine learning techniques, namely Deep Convolutional Neural Networks (CNN), in process of decision making in selected medical problems. After the survey of the most successful applications of CNN in solving medical problems, the paper focuses on the very difficult problem of automatic analyses of the skin lesions. The authors propose the CNN structure...
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Auditory-visual attention stimulator
PublikacjaNew approach to lateralization irregularities formation was proposed. The emphasis is put on the relationship between visual and auditory attention stimulation. In this approach hearing is stimulated using time scale modified speech and sight is stimulated by rendering the text of the currently heard speech. Moreover, displayed text is modified using several techniques i.e. zooming, highlighting etc. In the experimental part of...
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Synthesis of 2-amino-2,6-dideoxy-D-glucitol-6-sulfonic acid as a potential antifungal agent.
PublikacjaGlucosamine-6P (GlcN-6P) synthase catalyzes the first committed step in the biosynthetic pathway leading to the formation of UDP-GlcNAc, a sugar nucleotide precursor providing D-glucosamine for the formation of chitin and manoproteins. 2-Amino-2,6-dideoxy-D-glucitol-6-sulfonic acid is an analog of 2-amino-2-deoxy-D-glucitol 6-phosphate (GlcN-ol-6-P), a known inhibitor of GlcN-6-P synthase, in which the phosphate group of the latter...