Search results for: major depressive disorder
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The importance of anchoring ligands of binuclear sensitizers on electron transfer processes and photovoltaic action in dye-sensitized solar cells
PublicationThe relatively low photon-to-current conversion efficiency of dye-sensitized solar cells is their major drawback limiting widespread application. Light harvesting, followed by a series of electron transfer processes, is the critical step in photocurrent generation. An in-depth understanding and fine optimization of those processes are crucial to enhance cell performance. In this work, we synthesize two new bi-ruthenium sensitizers...
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Earthquake-induced pounding between asymmetric steel buildings
PublicationEarthquake-induced pounding between buildings has been the subject of numerous numerical and experimental studies in the resent years. The phe-nomenon may cause severe damage to structural elements as well as may also lead to the total collapse of colliding structures. A major reason leading to pounding between adjacent, insufficiently separated buildings results from the differences in their dynamic properties. The aim of this...
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MSRL and the Real-Life Processes of Capturing and Implementing the "Urban Innovation"
PublicationResult of the MSRL workshop, five research projects, reflect on a broader process of exchange of the ideas between the cities, that is occurring in the real life and became one of the driving factors of the urban development nowadays. The objective of the MSRL research - concepts, which help to advance the development of the cities, support the improvement of the quality of urban environment or meet the future challenges, can be...
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Rapid simulation-driven design of miniaturised dual-band microwave couplers by means of adaptive response scaling
PublicationOne of the major challenges in the design of compact microwave structures is the necessity of simultaneous handling of several objectives and the fact that expensive electromagnetic (EM) analysis is required for their reliable evaluation. Design of multi-band circuits where performance requirements are to be satisfied for several frequencies at the same time is even more difficult. In this work, a computationally efficient design...
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A case study of odour nuisance evaluation in the context of integrated urban planning
PublicationOdour nuisance poses a serious problem in many urban areas, yet its evaluation and mitigation is often omitted in the urban planning process. By identifying its range and spatio-temporal variations, it could be taken into consideration by planners in urban development strategies and land use decisions. The aim of the study was to present the application of odour evaluation techniques in the improvement of the quality of life in...
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Modulation of CYP1A1, CYP1A2 and CYP1B1 expression by cabbage juices and indoles in human breast cell lines
PublicationEpidemiological studies have shown that consumption of cab- bage and sauerkraut is connected with significant reduction of breast cancer incidences. Estrogens are considered a major breast cancer risk factor and their metabolism by P450 enzymes substan- tially contributes to carcinogenic activity. The aim of this study was to investigate the effect of cabbage and sauerkraut juices of differ- ent origin on the expression profile...
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Behaviour of deformed steel columns exposed to impact load during earthquakes - experimental study
PublicationIt has been observed during major earthquakes that the so called soft-storey failure of an upper floor of a structure results in large impact load acting on structural members of the lower storeys. It may further lead to progressive collapse of the whole structure substantially intensifying human and material losses. The aim of this paper is to investigate experimentally the behaviour of horizontally deformed columns (deformation...
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Composition of fatty acids in selected sorts of biscuits, offered for children
PublicationThe fatty acid (FA) composition, especially total trans-fatty acids (TFA) content in 12 assortments of biscuits offered for children, produced by four different companies, were determined by gas chromatography. Total fat content of the biscuit samples ranged from 2.2 to 22.8 g/100 g of product. The major FAs were palmitic C16:0, oleic C18:1, and linoleic C18:2 acids. Depending on the biscuit type, the total saturated fatty acids...
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Molecular hydrogen solvated in water – A computational study
PublicationThe aqueous hydrogen molecule is studied with molecular dynamics simulations at ambient temperature and pressure conditions, using a newly developed flexible and polarizable H2 molecule model. The design and implementation of this model, compatible with an existing flexible and polarizable force field for water, is presented in detail. The structure of the hydration layer suggests that first-shell water molecules accommodate the...
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Weldability of pipe grade polyethylenes as realized from thermal and mechanical properties assessments
PublicationSince polyethylene (PE) has been widely accepted for the production of high-pressure fluid conveying pipelines, studies devoted to weldability of PE connections were always of major importance. In this study, two industrial PE grades designed for pipe production, namely PE80 and PE100, were injection molded, cut, and then welded as PE100-PE100, PE100-PE80, and PE80-PE80. The heat-welded joints were assessed by differential scanning...
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Untargeted Lipidomics Reveals Differences in the Lipid Pattern among Clinical Isolates of Staphylococcus aureus Resistant and Sensitive to Antibiotics
PublicationStaphylococcus aureus resistance to antibiotics is a significant clinical problem worldwide. In this study, an untargeted lipidomics approach was used to compare the lipid fingerprints of S. aureus clinical isolates that are resistant and sensitive to antibiotics. High-performance liquid chromatography coupled with time-of-flight mass spectrometry was employed to rapidly and comprehensively analyze bacterial lipids. Chemometric...
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Synthesis and characterisation of polyurethane elastomers with semi-products obtained from polyurethane recycling
PublicationIn this work polyurethane elastomers were synthesised by using different mixtures of a petrochemical and glycerolysate polyols and 4,4-diphenylmethane diisocyanate (MDI). Glycerolysate polyol was produced from polyurethane foam decomposition using crude glycerine as a decomposition agent. The structure and thermal properties of obtained semi-product were similar to the polyol used in the synthesis of original foam. Glycerolysate...
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Thermoplastic polyurethanes with glycolysate intermediates from polyurethane waste recycling
PublicationThe polyol is a major component in polyurethane formulations and therefore introducing to the formulation recycled polyol (obtained during decomposition process) allows decreasing the usage of pure petrochemical components. In this work, thermoplastic polyurethanes were prepared using various mixtures of a petrochemical macrodiol poly(ethylene-butylene adipate)diol (PEBA) and a recycled glycolysate intermediate, called glycolysate...
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THE COST ANALYSIS OF CORROSION PROTECTION SOLUTIONS FOR STEEL COMPONENTS IN TERMS OF THE OBJECT LIFE CYCLE COST
PublicationSteel materials, due to their numerous advantages - high availability, easiness of processing and possibility of almost any shaping are commonly applied in construction for carrying out basic carrier systems and auxiliary structures. However, the major disadvantage of this material is its high corrosion susceptibility, which depends strictly on the local conditions of the facility and the applied type of corrosion protection system....
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Domain segmentation for low-cost surrogate-assisted multi-objective design optimisation of antennas
PublicationAbstract: Information regarding the best possible design trade-offs of an antenna structure can be obtained through multiobjective optimisation (MO). Unfortunately, MO is extremely challenging if full-wave electromagnetic (EM) simulation models are used for performance evaluation. Yet, for the majority of contemporary antennas, EM analysis is the only tool that ensures reliability. This study introduces a procedure for accelerated...
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The Analysis of Overall Ship Fuel Consumption in Acceleration Manoeuvre using Hull-Propeller-Engine Interaction Principles and Governor Features
PublicationThe problem of reduction of greenhouse gas emissions in shipping is currently addressed by many research works and related industries. There are many existing and visionary technologies and ideas, which are conceptually defined or practically realised. This goal can be achieved in different ways, and reducing fuel consumption is one of the major methods. In these circumstances, the aim of this study is to analyse the possibility...
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How Can We Identify Electrophysiological iEEG Activities Associated with Cognitive Functions?
PublicationElectrophysiological activities of the brain are engaged in its various functions and give rise to a wide spectrum of low and high frequency oscillations in the intracranial EEG (iEEG) signals, commonly known as the brain waves. The iEEG spectral activities are distributed across networks of cortical and subcortical areas arranged into hierarchical processing streams. It remains a major challenge to identify these activities in...
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Comparative Study on Assisted Solvent Extraction Techniques for the Extraction of Biologically Active Compounds from Sideritis raeseri and Sideritis scardica
PublicationThe plants in the Sideritis genus are postulated to exhibit several important medicinal properties due to their unique chemical composition. To isolate the targeted phytochemical compounds, the selection of a suitable extraction method is of primary importance. In this work, a comparative study on the phytochemical profiles of various Sideritis raeseri and Sideritis scardica extracts has been carried out. An untargeted metabolomics...
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Concentration‐Induced Hetero‐Valent Partial‐Inverse Occupation of Infrared Phosphor
PublicationInfrared luminescent materials have evoked much attention from chemists and material scientists. Although substantial progress is made in materials design, the luminescent mechanism remains ambiguous in the complex structures, presenting major barriers to developing novel infrared luminescent materials. Herein, this study aims to deliberate a complete discussion on infrared phosphors with concentration-induced hetero-valent partial-inverse...
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Deep eutectic solvents – Ideal solution for clean air or hidden danger?
PublicationThe industrial sector is one of the fastest-growing sources of greenhouse gases, due to its excessive energy consumption to meet the rapidly growing demand for energy-intensive products. The use of deep eutectic solvents (DESs) has been studied extensively in order to cope with these harmful gases, but their usage can be an issue in respect to ecological reasons. Do deep eutectic solvents harm the atmosphere? Yes, these solvents...
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Security of Cryptocurrencies: A View on the State-of-the-Art Research and Current Developments
Publication[Context] The goal of security is to protect digital assets, devices, and services from being disrupted, exploited or stolen by unauthorized users. It is also about having reliable information available at the right time. [Motivation] Since the inception in 2009 of the first cryptocurrency, few studies have been undertaken to analyze and review the state-of-the-art research and current developments with respect to the security...
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Reactive imines: Addition of 2-aminopyrimidine to the imine bond and isolation of the aminal from the equilibrium mixture aminal/imine
PublicationThe reaction between o-vanillin and 2-aminopyrimidine leads to the formation of a single crystalline product: aminal, 1, which results from the reaction of the initially formed imine with 2-aminopyrimidine. The reaction was followed by the NMR spectroscopy. VT NMR studies prove that in solution two major species are observed: aminal and imine and their ratio depends on the time or/and temperature with the imine content increasing...
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Metoda i algorytmy modyfikacji sygnału do celu wspomagania rozumienia mowy przez osoby z pogorszoną rozdzielczością czasową słuchu
PublicationPrzedmiotem badań przeprowadzonych w ramach rozprawy są metody modyfikacji czasu trwania sygnału (ang. Time Scale Modification –TSM) mowy operujące w czasie rzeczywistym oraz ocena ich wpływu na rozumienie wypowiedzi przez osoby z pogorszoną rozdzielczością czasową słuchu. Pogorszona rozdzielczość słuchu jest jednym z symptomów związanych z ośrodkowymi zaburzeniami słuchu (ang. Cetnral Auditory Processing Disorder – CAPD). W odróżnieniu...
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Powikłania po rekonstrukcji piersi: problem zakażeń i strategii prewencyjnej - przegląd literaturowy
PublicationW niniejszej pracy przedstawiono dane dotyczące powikłań po rekonstrukcji piersi. Manuskrypt ma na celu usystematyzowanie wyników badań z ostatnich lat wraz z aspektami, takimi jak: częstotliwość występowania powikłań oraz ich rodzaj, czynniki predysponujące, a także możliwości profilaktyki. Przeanalizowano dane literaturowe z ogólnie dostępnych artykułów z okresu ostatnich pięciu lat, ze szczególnym uwzględnieniem zakażeń. Do...
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Identification of Substrates of Cytoplasmic Peptidyl-Prolyl Cis/Trans Isomerases and Their Collective Essentiality in Escherichia Coli
PublicationProtein folding often requires molecular chaperones and folding catalysts, such as peptidyl-prolyl cis/trans isomerases (PPIs). The Escherichia coli cytoplasm contains six well-known PPIs, although a requirement of their PPIase activity, the identity of their substrates and relative enzymatic contribution is unknown. Thus, strains lacking all periplasmic and one of the cytoplasmic PPIs were constructed. Measurement of their PPIase...
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The Product of Matrix Metalloproteinase Cleavage of Doxorubicin Conjugate for Anticancer Drug Delivery: Calorimetric, Spectroscopic, and Molecular Dynamics Studies on Peptide–Doxorubicin Binding to DNA
PublicationMatrix metalloproteinases (MMPs) are extracellular matrix degradation factors, promoting cancer progression. Hence, they could provide an enzyme-assisted delivery of doxorubicin (DOX) in cancer treatment. In the current study, the intercalation process of DOX and tetrapeptide-DOX, the product of the MMPs' cleavage of carrier-linked DOX, into dsDNA was investigated using stationary and time-resolved fluorescence spectroscopy, UV-Vis...
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Impact of soluble organic matter and particulate organic matter on anammox system: Performance, microbial community and N2O production
PublicationIn this study, the effects of soluble readily biodegradable COD (sCOD) and particulate slowly biodegradable COD (pCOD) on anammox process were investigated. The results of the longterm experiment indicated that a low sCOD/N ratio of 0.5 could accelerate the anammox and denitrification activity, to reach as high as 84.9% ±2.8% TN removal efficiency. Partial denitrification-anammox (PDN/anammox) and denitrification were proposed...
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The comparison of cytotoxic and genotoxic activities of glucosinolates, isothiocyanates, and indoles
PublicationChemopreventive properties of Brassica vegetables are attributed mainly to their characteristic compounds—glucosinolates (GLs) and their main hydrolysis products—isothiocyanates (ITCs) and indoles. In this study, we compared antiproliferative activity (MTT test in HT29 cells) and genotoxic effects (comet assay in HT29 cells and restriction analysis in a cell-free system) of three GLs (sinigrin (SIN), glucotropaeolin (GTL), and...
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Individual entrepreneurial orientation: comparison of business and STEM students
PublicationAbstract Purpose – The purpose of this study is to determine whether there are differences in Individual Entrepreneurial Orientation (IEO) between students who are doing their major in business studies and the ones whose areas of study are science, technology, engineering, and mathematics (STEM). Design/methodology/approach – The current research investigates which factors and components contribute to EO orientation development...
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Fatty acyl benzamido antibacterials based on inhibition of DnaK-catalyzed protein folding
PublicationWe have reported that the hsp70 chaperone DnaK from Escherichia coli might assist protein folding by catalyzing the cis/trans isomerization of secondary amide peptide bonds in unfolded or partially folded proteins. In this study a series of fatty acylated benzamido inhibitors of the cis/trans isomerase activity of DnaK was developed and tested for antibacterial effects in E. coli MC4100 cells. Nα-[Tetradecanoyl-(4-aminomethylbenzoyl)]-l-asparagine...
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The influence of ILs on TiO2 microspheres activity towards 5-FU removal under artificial sunlight irradiation
PublicationIn this work, the effect of various ionic liquids (ILs), namely, choline chloride [Chol][Cl], hexadecylpyridynium chloride [HDPy][Cl], and tributylmethylammonium chloride [TBMA][Cl], on the morphology, surface compo-sition in relation to photocatalytic oxidation of 5-fluorouracil (5-FU) and phenol in the presence of TiO2 pho-tocatalysts under artificial sunlight conditions was investigated. The highest photoactivity towards cytostatic...
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Towards azeotropic MeOH-MTBE separation using pervaporation chitosan-based deep eutectic solvent membranes
PublicationDeep eutectic solvents (DESs) are a new class of solvents that can offset some of the major drawbacks of common solvents and ionic liquids. When dealing with the preparation of dense membranes, the use of DESs is still challenging due to their low compatibility with the polymer phase. In this research, a novel L-proline:sulfolane (molar ratio 1:2) DES was synthesized and used for the preparation of more sustainable bio-based membranes...
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A note on the applications of artificial intelligence in the hospitality industry: preliminary results of a survey
PublicationIntelligent technologies are widely implemented in different areas of modern society but specific approaches should be applied in services. Basic relationships refer to supporting customers and people responsible for services offering for these customers. The aim of the paper is to analyze and evaluate the state-of-the art of artificial intelligence (AI) applications in the hospitality industry. Our findings show that the major...
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Antibiotic resistance in wastewater, does the context matter? Poland and Portugal as a case study
PublicationAntibiotic resistance has been considered a major human health threat that may endanger the success of medicine. Recent studies have unveiled worldwide asymmetries of antibiotic resistance occurrence, being factors as diverse as climate, socioeconomic, or antibiotic use possible drivers of such asymmetric distribution. In Europe, where clinical antibiotic resistance is surveyed for more than 20 years, the European Center for Disease...
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Influence of Surface Modification of Titanium and Its Alloys for Medical Implants on Their Corrosion Behavior
PublicationTitanium and its alloys are often used for long-term implants after their surface treatment. Such surface modification is usually performed to improve biological properties but seldom to increase corrosion resistance. This paper presents research results performed on such metallic materials modified by a variety of techniques: direct voltage anodic oxidation in the presence of fluorides, micro-arc oxidation (MAO), pulse laser treatment,...
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Expedited Globalized Antenna Optimization by Principal Components and Variable-Fidelity EM Simulations: Application to Microstrip Antenna Design
PublicationParameter optimization, also referred to as design closure, is imperative in the development of modern antennas. Theoretical considerations along with rough dimension adjustment through supervised parameter sweeping can only yield initial designs that need to be further tuned to boost the antenna performance. The major challenges include handling of multi-dimensional parameter spaces while accounting for several objectives and...
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Robust Parameter Tuning of Antenna Structures by Means of Design Specification Adaptation
PublicationParameter tuning through numerical optimization has become instrumental in the design of high-performance antenna systems. Yet, practical optimization faces several major challenges, including high cost of massive evaluations of antenna characteristics, normally involving full-wave electromagnetic (EM) analysis, large numbers of adjustable variables, the shortage of reasonable initial solutions in the case of topologically complex...
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Mining Knowledge of Respiratory Rate Quantification and Abnormal Pattern Prediction
PublicationThe described application of granular computing is motivated because cardiovascular disease (CVD) remains a major killer globally. There is increasing evidence that abnormal respiratory patterns might contribute to the development and progression of CVD. Consequently, a method that would support a physician in respiratory pattern evaluation should be developed. Group decision-making, tri-way reasoning, and rough set–based analysis...
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Sources and composition of chemical pollution in Maritime Antarctica (King George Island), part 2: Organic and inorganic chemicals in snow cover at the Warszawa Icefield
PublicationThe study area is located on King George Island, where 90% of the area is permanently glaciated. This study provides a comprehensive analysis of the inorganic and organic chemistry of snow cover in the icefield and a comparison against previous results obtained in fresh water. Snow samples were collected in the summer of 2017 in the Warszawa Icefield area. Sampling points are located along two transects: between the Arctowski Polish...
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Albumin–Hyaluronan Interactions: Influence of Ionic Composition Probed by Molecular Dynamics
PublicationThe lubrication mechanism in synovial fluid and joints is not yet fully understood. Nevertheless, intermolecular interactions between various neutral and ionic species including large macromolecular systems and simple inorganic ions are the key to understanding the excellent lubrication performance. An important tool for characterizing the intermolecular forces and their structural consequences is molecular dynamics. Albumin...
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Analytical design method for widening the intertrack space
PublicationThe paper involved the issue of arching of the railway turnouts. This is an issue which is given relatively less attention to scientific and research activities. Reference has been made to the book by Wladyslaw Rzepka, under the title „Curved turnouts in plan and profile”, which has been used in Poland for more than 50 years as the main source of information relating to the turnouts on the curve. The book is a compilation of elaborations...
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Reclaimed rubber in-situ grafted with soybean oil as a novel green reactive plasticizer in SBR/silica compounds
PublicationPolymer recycling and biodegradable polymeric materials are two major routes towards the sustainable development of polymer materials which contributes to the management of waste. In this regard, an eco-friendly approach is presented wherein high reclaiming degree of ground tire rubber (GTR) was achieved by low-temperature oxidation under swollen action of soybean oil. In-situ reclaimed GTR with soybean oil was cured into reactive...
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Non-conventional approach in single-sided lapping process: kinematic analysis and parameters optimization
PublicationThe lapping process is strongly affected by a number of input parameters. One of the fundamental mechanical processes in lapping is the abrasive effect of particles. In order to examine the influence of the kinematic parameters on the lapping uniformity of unconventional single-sided machine, numerical simulations of particles sliding trajectories are performed. Changing the kinematic parameters, e.g., rotational velocities or...
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Endothelial dysfunction due to eNOS uncoupling: molecular mechanisms as potential therapeutic targets
PublicationNitric oxide (NO) is one of the most important molecules released by endothelial cells, and its antiatherogenic properties support cardiovascular homeostasis. Diminished NO bioavailability is a common hallmark of endothelial dysfunction underlying the patho‑ genesis of the cardiovascular disease. Vascular NO is synthesized by endothelial nitric oxide synthase (eNOS) from the substrate L‑arginine (L‑Arg), with tetrahydrobiopterin...
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Short-Term Observations of Rainfall Chemistry Composition in Bellsund (SW Spitsbergen, Svalbard)
PublicationGlobal warming results in increasingly widespread wildfires, mostly in Siberia, but also in North America and Europe, which are responsible for the uncontrollable emission of pollutants, also to the High Arctic region. This study examines 11 samples of rainfall collected in August in a coastal area of southern Bellsund (Svalbard, Norway). It covers detailed analysis of major ions (i.e., Cl−, NO3−, and SO42−) and elements (i.e.,...
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An improvement of body surface area formulas using the 3D scanning technique
PublicationObjectives: Body surface area (BSA) is one of the major parameters used in several medical fields. However, there are concerns raised about its usefulness, mostly due to the ambiguity of its estimation. Material and Methods: Authors have conducted a voluntary study to investigate BSA distribution and estimation in a group of 179 adult people of various sex, age, and physique. Here, there is provided an extended analysis of the...
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Protection and renovation of public areas in a modernist city: the case of three streets in the historic City Centre of Gdynia
PublicationThis article concerns issues related to the preservation and restoration of public space in Gdynia’s city centre, which was designed and built mainly in the 1920s and 1930s. In 2007, a major part of the city centre was entered into the register of monuments asa historic complex of urban architecture. Moreover, in 2015, the area was declared a Monument of History. Protection of a complex of urban architecture covers not only the...
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Expedited antenna optimization with numerical derivatives and gradient change tracking
PublicationDesign automation has been playing an increasing role in the development of novel antenna structures for various applications. One of its aspects is electromagnetic (EM)-driven design closure, typically applied upon establishing the antenna topology, and aiming at adjustment of geometry parameters to boost the performance figures as much as possible. Parametric optimization is often realized using local methods given usually reasonable...
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ROYAL CHAPEL IN GDANSK. STUDY OF FACILITY INVENTORY WITH THE USAGE OF LASER SCANNING WITHIN THE FRAMES OF STUDENT PROJECT
PublicationThis article presents the photogrammetric works carried out during the architectural inventory of the Royal Chapel in the Main Town of Gdansk (Poland). The facility has the status of a monument of architecture and since decades it is covered by geodetic monitoring, realized with the participation of the Department of Geodesy of Faculty of Civil and Environmental Engineering of Gdańsk University of Technology . For several years,...
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Arching of railway turnouts by analytical design method
PublicationThe paper involved the issue of arching of the railway turnouts. This is an issue which is given relatively less attention to scientific and research activities. Reference has been made to the book by Wladyslaw Rzepka, under the title „Curved turnouts in plan and profile”, which has been used in Poland for more than 50 years as the main source of information relating to the turnouts on the curve. The book is a compilation of elaborations...