Search
Filters
total: 1543
displaying 1000 best results Help
Search results for: tandem mass spectrometry
-
Novel decahedral TiO2 photocatalysts modified with Ru or Rh NPs: Insight into the mechanism
PublicationNovel decahedral TiO2 modified with Ru or Rh NPs were successfully synthesized by hydrothermal method. The effect of metal type as well as amount of noble metal precursor (0.05, 0.1, 0.2, 0.3 and 0.5 wt.%) on the photocatalytic activity were investigated. Decahedral TiO2 decorated by Ru and Rh nanoparticles was prepared by photodeposition method, whereas Rh doped TiO2 was obtained by onestep hydrothermal method with introduction...
-
Quality of limes juices based on the aroma and antioxidant properties
PublicationKaffir (Citrus hystrix) and Key (Citrus aurantifolia) limes juices were investigated and compared. Two dimensional gas chromatography coupled with time-of-flight mass spectrometry (GC×GC-TOF-MS) was applied to assess the botanical origin of Kaffir and Key limes juices, based on volatile substances. The biggest differences in the contents of selected terpenes in Kaffir and Key limes occur in chemical compounds such as Limonene,...
-
Electrochemical simulation of metabolic reduction and conjugation reactions of unsymmetrical bisacridine antitumor agents, C-2028 and C-2053
PublicationElectrochemistry (EC) coupled with analysis techniques such as liquid chromatography (LC) and mass spectrometry (MS) has been developed as a powerful tool for drug metabolism simulation. The application of EC in metabolic studies is particularly favourable due to the low matrix contribution compared to in vitro or in vivo biological models. In this paper, the EC(/LC)/MS system was applied to simulate phase I metabolism of the representative...
-
Diamond Nanofilm Normalizes Proliferation and Metabolism in Liver Cancer Cells
PublicationPurpose: Surgical resection of hepatocellular carcinoma can be associated with recurrence resulting from the degeneration of residual volume of the liver. The objective was to assess the possibility of using a biocompatible nanofilm, made of a colloid of diamond nanoparticles (nfND), to fill the side after tumour resection and optimize its contact with proliferating liver cells, minimizing their cancerous transformation. Methods:...
-
Uptake, accumulation, and translocation of Zn, Cu, Pb, Cd, Ni, and Cr by P. australis seedlings in an urban dredged sediment mesocosm: impact of seedling origin and initial trace metal content
PublicationThe study presents results from 6 months of phytoremediation of sediments dredged from three urban retention tanks carried out in a mesocosm setup with the use of P. australis. Two kinds of P. australis seedlings were considered: seedlings originating from natural (uncontaminated - Suncont) and anthropogenically changed environments (contaminated – Scont); this distinction was reflected in the baseline concentrations of trace metals...
-
Synthesis and Structure of Novel Hybrid Compounds Containing Phthalazin-1(2H)-imine and 4,5-Dihydro-1H-imidazole Cores and Their Sulfonyl Derivatives with Potential Biological Activities
PublicationA novel hybrid compound—2-(4,5-dihydro-1H-imidazol-2-yl)phthalazin-1(2H)-imine (5) was synthesized and converted into di-substituted sulfonamide derivatives 6a–o and phthalazine ring opening products—hydrazonomethylbenzonitriles 7a–m. The newly prepared compounds were characterized using elemental analyses, IR and NMR spectroscopy, as well as mass spectrometry. Single crystal X-ray diffraction data were collected for the representative...
-
Anti-cancer effect of Rumex obtusifolius in combination with arginase/nitric oxide synthase inhibitors via downregulation of oxidative stress, inflammation, and polyamine synthesis
PublicationCancer continues to be a leading cause of death worldwide, making the development of new treatment methods crucial in the fight against it. With cancer incidence rates increasing worldwide, ongoing research must focus on identifying new and effective ways to prevent and treat the disease. The combination of herbal extracts with chemotherapeutic agents has gained much interest as a novel strategy to combat cancer. Rumex obtusifolius...
-
Unlocking the Secrets of River Pollution: Analyzing Organic Pollutants in Sediments—Experimental Study
PublicationUntreated wastewater released into rivers can result in water pollution, the spread of waterborne diseases, harm to ecosystems, contamination of soil and groundwater, as well as air pollution and respiratory problems for nearby humans and animals due to the release of greenhouse gases. The current study aims to investigate the recent input of anthropogenic loads into the rivers using linear alkylbenzene (LAB), which is one of the...
-
An experimental investigation on the effect of new continuous core-baffle geometry on the mixed convection heat transfer in shell and coil heat exchanger
PublicationIn the article, the authors presented the influence of continuous core-baffle geometry at mixed convection heat transfer in shell and coil heat exchanger. Experiments were carried out for a large power range, i.e. from 100W to 1200W and mass flow rates ranging from 0.01 kg/s to 0.025 kg/s. During the experiments, the mass flow rate of cooling water, the temperature of water at the inlet and outlet as well as the wall temperature...
-
Parametric optimization of sandwich composite footbridge with U-shaped cross-section
PublicationParametric optimization of sandwich composite footbridge was presented in the paper. Composite footbridge has 14,5 m long and has U-shaped cross-section with inner dimensions 2,6 × 1,3 m. The sandwich structure in made from GFRP laminate as a faces and PET foam as a core. The aim of analysis was to minimize the mass of the new footbridge that can lead to minimize the cost of structure. After optimization was conducted, the new...
-
How proteins bind to DNA: target discrimination and dynamic sequence search by the telomeric protein TRF1
PublicationTarget search as performed by DNA-binding proteins is a complex process, in which multiple factors contribute to both thermodynamic discrimination of the target sequence from overwhelmingly abundant off-target sites and kinetic acceleration of dynamic sequence interrogation. TRF1, the protein that binds to telomeric tandem repeats, faces an intriguing variant of the search problem where target sites are clustered within short fragments...
-
DYNWIR S-70 program for modal analysis of multisupported and multimass rotors
PublicationThe article provides a brief description of the program Dynwir-S-70 (currently being developed in the Rotor Dynamics and Slide Bearings Department in the Institute of Fluid-Flow Machinery Polish Academy of Sciences in Gdansk) which is a program for analysis of multi-supported and multi-mass rotors. Used algorithms and the construction of mass and stiffness matrix were presented. Damping matrix structure based on Rayleigh damping...
-
Ionization and fragmentation of furan molecules by electron collisions
PublicationCation mass spectra obtained by electron impact were measured to investigate the ionization and ionic fragmentation of furan, C4H4O, molecules in the gas phase. The most abundant cations, with comparable intensities in the mass spectra, were the parent, C4H4O+, cation (68 amu) and the C3H3+ fragment (39 amu). The appearance energies of most of the observed ionic fragments were determined and the possible fragmentation processes...
-
MONTE CARLO MODELING OF OPTICAL SENSOR FOR POST-OPERATIVE FREE FLAP MONITORING
PublicationAfter a preliminary study of the currently employed methods in vitality monitoring of the tissue flaps (TRAM, DIEP, SIEA), a usefulness of optical techniques is discussed. It seems that one of the most promising in monitoring tissue flaps blood flow is a near infrared spectrometry (NIRS). However, a special design of a measurement sensor has to be developed. First, basing on the literature study an optical “window” is characterized....
-
Flow Maps and Flow Patterns of R1233zd(E) in a Circular Minichannel at Low, Medium and High Values of Saturation Pressure
PublicationThere is a gap in knowledge regarding the flow pattern of low-boiling working fluids in the range of high saturation temperatures (above 120°C) and medium and high reduced pressures (0.5-0.9). Data are present in the literature for similar values of reduced pressures, but for lower values of saturation temperature. This is due to the existing refrigeration applications of these working fluids. At high values of reduced pressure,...
-
OTHER AN UNSPECIFIED FEMALE GENITAL ORGANS, Fallopian tube - Female, 39 - Tissue image [3300730069394241]
Open Research DataThis is the histopathological image of OTHER AN UNSPECIFIED FEMALE GENITAL ORGANS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Structure analysis and thermal degradation characteristics of bio-based poly(propylene succinate)s obtained by using different catalyst amounts
PublicationLinear bio-based polyester polyols were prepared with the use of succinic acid and 1.3-propanediol (both with natural origin). As a catalyst was used tetraisopropyl orthotitanate (TPT). In order to determine the effect of various catalyst content on the thermal degradation characteristics, three different TPT amounts, as a 1.3-propanediol equivalent, were used, namely 0.1 mass% (PPS-0.1), 0.2 mass% (PPS-0.2) and 0.25 mass% (PPS-0.25)....
-
Spinning Fluids Reactor: A new design of a gas – liquid contactor
PublicationCurrent trends in chemical reactor design are based on adapting these to the requirements of a particular chemical process. Processes involving reactions between the gas and liquid phase in particular require precise adjustment of all parameters. The common denominator for most modern design solutions is enhancement of the mass transfer area and the overall volumetric mass transfer coefficient. Gas – liquid contactors evolved from...
-
Wpływ sposobu odwzorowania pojazdu szynowego na odpowiedź dynamiczną przęsła mostowego
PublicationW pracy przedstawiono rezultaty analiz numerycznych oraz badań eksploatacyjnych dwóch przęseł mostowych wymuszonych ruchomym pojazdem szynowym. Pojazd odwzorowano za pomocą czterech modeli uproszczonych: strumienia sił skupionych, strumienia mas skupionych oraz strumieni oscylatorów jedno- i dwumasowych. Analizy numeryczne wykonano przy wykorzystaniu MES. Potrzebne parametry dynamiczne wyznaczono na podstawie wyników identyfikacji...
-
Isotope shifts of multipole lines of Pb I and Pb II
PublicationStudies of isotope shifts of three multipole lines between levels of the ground configuration 6s26p2 of Pb I, i.e.: 461.9 nm(1S0→3P1), 531.5 nm(1S0→3P2) and 733.2 nm(1D2→3P1), as well as 710.2 nm line (6s26p2P3∕2→6s26p2P1∕2) of Pb II are presented. We determined the isotope shifts between four stable isotopes: 204, 206, 207, 208. By the use of King plot analysis we were able to separate the mass and the field shifts. We found that...
-
Implementation of DEIS for reliable fault monitoring and detection in PEMFC single cells and stacks
PublicationDynamic Electrochemical Impedance Spectroscopy (DEIS) was presented as novel method for diagnostic and monitoring of PEMFC stack and single cells operation. Impedance characteristics were obtained simultaneously with current - voltage characteristics for stack and each individual cell. Impedance measurements were performed in galvanodynamic mode. It allowed to compare performance of each cell and identification of faulty cell operation...
-
Dissociation of furan-2-carboxylic acid by low energy electrons
PublicationElectron attachment to molecular target can lead to a variety of negative fragment ions. We experi- mentally probe the main dissociative electron attachment channels in furan-2-carboxylic acid (C3H3O2 − COOH) - a molecular target composed of two important structural units: a furan ring and a carboxylic group. In our studies we utilise nearly mono-energetic electrons at electron energies from 0 eV up to 15 eV. Our detection setup...
-
Channel Blockage and Flow Maldistribution during Unsteady Flow in a Model Microchannel Plate heat Exchanger
PublicationThis paper describes the problem of channel blockage as a result of flow maldistribution between the channels of a model mini channel plate heat exchanger consisting of one pass on each leg. Each leg of the heat exchanger contains 51 parallel and rectangular minichannels of four hydraulic diameters namely 461 μm, 571 μm, 750 μm and 823 μm. In addition, a more complex geometry has been investigated where for the sake of breaking...
-
Biomass estimation using a length-weight relationship in beetle larvae (Coleoptera: Aphodiidae, Histeridae, Hydrophilidae, Staphylinidae) obtained from cow dung
PublicationThis research enabled the relationship between length and dry body mass to be determined for 158 beetle larvaetaken from cow dung in north-eastern Poland. The larvae were divided into three morphological types, for which the power and linear function of the body length-weight relationship were determined. The linear regression equation characterizes the relationship between body weight and...
-
Evaluation of the Greenness of Analytical Procedures
PublicationThis contributions introduces the need to develop the methods to evaluate analytical procedures in the light of green analytical chemistry. Green chemistry metrics are not applicable in analytical chemistry because they refer to the mass of product and no product with mass is generated during analytical determination. Analytical greenness evaluations are based on scoring - such as NEMI or Eco-scale or comparative analysis as it...
-
Teratoma, malignant, NOS - Female, 39 - Tissue image [3300730069393181]
Open Research DataThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Teratoma, malignant, NOS - Female, 39 - Tissue image [3300730069392881]
Open Research DataThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Teratoma, malignant, NOS - Female, 39 - Tissue image [3300730069393031]
Open Research DataThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Teratoma, malignant, NOS - Female, 39 - Tissue image [3300730069395221]
Open Research DataThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Teratoma, malignant, NOS - Female, 39 - Tissue image [3300730069395471]
Open Research DataThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Teratoma, malignant, NOS - Female, 39 - Tissue image [330073006939961]
Open Research DataThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Teratoma, malignant, NOS - Female, 39 - Tissue image [3300730069399491]
Open Research DataThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Teratoma, malignant, NOS - Female, 39 - Tissue image [3300730069394661]
Open Research DataThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Teratoma, malignant, NOS - Female, 39 - Tissue image [3300730069393991]
Open Research DataThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Teratoma, malignant, NOS - Female, 39 - Tissue image [3300730069394531]
Open Research DataThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Teratoma, malignant, NOS - Female, 39 - Tissue image [3300730069398381]
Open Research DataThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Teratoma, malignant, NOS - Female, 39 - Tissue image [3300730069394761]
Open Research DataThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Chemical and biological stability of polyene macrolides
PublicationThe polyene macrolide antibiotics have been used in an-tifungal therapy since first o f them were discovered in 1950's. Up to now, four polyene macrolides are being used in medical practice, namely amphotericin B, nystatin, candi-cidin and pimaricin.The antifungal activity and mode of ac-tion of polyene macrolides is determined by their structure, chemical and physical properties.The main fragment of polyene...
-
Prediction of Overall In Vitro Microsomal Stability of Drug Candidates Based on Molecular Modeling and Support Vector Machines. Case Study of Novel Arylpiperazines Derivatives
PublicationOther than efficacy of interaction with the molecular target, metabolic stability is the primary factor responsible for the failure or success of a compound in the drug development pipeline. The ideal drug candidate should be stable enough to reach its therapeutic site of action. Despite many recent excellent achievements in the field of computational methods supporting drug metabolism studies, a well-recognized procedure to model...
-
Identification of plate dynamic parameters for structural health monitoring
PublicationPraca przedstawia technikę wyznaczania parametrów modalnych wykorzystywanych w diagnostyce konstrukcji. Modalna masa, sztywność, tłumienie i postacie drgań wyznaczone są dla prostokątnej stalowej płyty na podstawie badań eksperymentalnych. Teoretyczne parametry modalne otrzymaneo z modelu MES. Omówiony został wpływ dodatkowej masy na parametry modalne konstrukcji.This paper presents a technique for modal parameters estimation for...
-
Maximum transportation growth in energy and solute particles in Prandtl martial across a vertical 3D-heated surface: Simulations achieved using by finite element approach
PublicationThe goal of this study is to determine the maximum energy and solute particles' transportation growth in a 3D-heated region of Prandtl martial through a dynamic magnetic field. The effects of this field on the properties of solvent molecules and heat conduction are studied. A correctly stated functional method and a finite element approach are comparable to a certain type of differential equations. In order demonstrate the effects...
-
Use of response surface methodology in characterization of properties of recycled high density polyethylene/ground tire rubber compositions
PublicationSearching for newways to utilize rubber and polymerwaste has been the focus of many studies conducted by research centers and companies worldwide. In this study, the influence of extrusion conditions on the properties of thermoplastic compositions containing post-production recycled high density polyethylene (PE-HD) and ground tire rubber (GTR) at 50:50 mass ratiowas examined. Response Surface Methodology (RSM) was used to determine...
-
A risk comparison framework for autonomous ships navigation
PublicationMaritime autonomous surface ships (MASS) may operate in three predefined operational modes (OM): manual, remote, or autonomous control. Determining the appropriate OM for MASS is important for operators and competent authorities that monitor and regulate maritime traffic in given areas. However, a science-based approach to this respect is currently unavailable. To assist the selection of the proper OM, this study presents a risk-based...
-
Teratoma, malignant, NOS - Female, 39 - Tissue image [3300730069396001]
Open Research DataThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Balance error generated by numerical diffusion in the solution of Muskingum equation
PublicationIn the paper the conservative properties of the lumped hydrological models with variable parameters are discussed. It is shown that in the case of the non-linear Muskingum equation the mass balance is not satisfied. The study indicates that the mass balance errors are caused by the improper form of equation and by the numerical diffusion which is generated in the solution. It has been shown that the classical way of derivation...
-
Hydrogen production from wood waste by mean of dark fermentation
PublicationThe utilization of wood wastes in clean and green chemistry method like by mean of dark fermentation, is a highly desired solution of waste management. In the article model for the estimation hydrogen potential of wood waste is given. The model has been used to calculate the potential theoretical hydrogen mass that can be produced from wood wastes in Pomerania and Silesia: pine, spruce, fir, beech and oak. In the introduction,...
-
Stability Investigation of the PCM Nanocomposites
PublicationEnsuring the stability is a key issue to be solved for the technical application of nanocomposites. In this work, fatty acid P1801 served as base phase change material (PCM)P1801, and its main ingredients are palmitic acid (58%) and stearic acid (38%). Titania (TiO2) and alumina (Al2O3) with mass concentrations of 1% and 5% were selected as nanoparticles, while polyvinylpyrrolidone (PVP) or oleic acid (OA) with mass concentrations...
-
Ozone nanobubble technology as a novel AOPs for pollutants degradation under high salinity conditions
PublicationConventional water treatment systems frequently exhibit diminished efficiency at high salinity - a significant issue especially for real industrial effluents - mostly due to the creation of intricate structures between pollutants and salts. One of the primary obstacles associated with high salinity conditions is the generation of by-products that pose additional hurdles for treatment. In this work, we have investigated the novel...
-
Przyczółki mostowe z konstrukcją odciążającą z gruntu zbrojonego geosyntetykami
PublicationPrzegląd najważniejszych cech geotekstyliów i wyrobów pokrewnych, zastosowanych do budowy bloków odciążających ze szczególnym uwzględnieniem ich wytrzymałości długo i krótkookresowej oraz reologii. Określenie obciążeń działających na konstrukcję gruntową współpracującą z przyczółkiem; obciążenia normowe i rzeczywiste. Obliczenia konstrukcji z gruntu zbrojonego współpracującej z przyczółkiem
-
Effect of Vascular Lumen Reduction on the Performance and Energy Consumption of an Innovative Implantable LVAD
PublicationThis paper presents the results of a study on the effect of vascular lumen reduction on the performance of an innovative implantable LVAD (left ventricular assist device). It details the pressures in the individual cardiac chambers as a function of device frequency. In addition, mass flow rates and energy consumption of the device are examined, varying with lumen reduction and operating frequency. While the lumen reduction of the...